Vfaba.Hedin2.R1.4g219800.2

Query:    5 KGEINVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            K E NV+K LHVA+LAFPFGTHA+PL+S+VRKIA E P VTFSFF+T  SNATLFS +++  LPNIKHY+V DGLPEGYVPSGHPLEPIF FIKAMPEN+K V+ EAV ET K ITC VTDAFYWF ADLA ++NAKWVP+WTAGPHALLTH YTDL+R        DV+    +PGFPEL+  DLPEGVI+D DGPF TMLHKMG  LPRATA++INSF+T+H +IEN+LNSKFKLLLNVGPF+LTTPQ  ISDE  CL WLN+H++FSVVYISFGS+IIPPPHEL+ALAESLEECGFPF+WA RG+P+E+ P GF+ERT  +GKIV+WAPQMEILKHSSVGVCLTH GWNSVL+CIVGGVPMISRPFFGDQK+NARM+ESVWEIGV V++GVL+KES +K L+L MSSE+G  MR+NIVKLKESAL+AV +NGTS KN  TLIQIVT
Sbjct:    7 KDETNVEK-LHVAILAFPFGTHASPLLSLVRKIAGEVPKVTFSFFTTTASNATLFSPNNDC-LPNIKHYNVDDGLPEGYVPSGHPLEPIFLFIKAMPENFKSVMDEAVAETGKDITCLVTDAFYWFAADLAQQINAKWVPLWTAGPHALLTHIYTDLLRHA-CKQVHDVQNVDLIPGFPELKVCDLPEGVIDDTDGPFATMLHKMGLELPRATAIAINSFATIHPLIENDLNSKFKLLLNVGPFMLTTPQPLISDEQGCLEWLNQHKNFSVVYISFGSTIIPPPHELIALAESLEECGFPFIWALRGDPKEKLPNGFLERTITKGKIVSWAPQMEILKHSSVGVCLTHCGWNSVLECIVGGVPMISRPFFGDQKLNARMLESVWEIGVGVDHGVLTKESTVKALKLIMSSEKGGVMRQNIVKLKESALKAVEQNGTSTKNFTTLIQIVT 452          

Query:    1 MSNSKGE-INVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSS---DEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNK-DDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            MS  KGE +NV+K LHVAVLAFPFGTHA PL+++ R+IA +A  VTFSF  T ++NA LFS S   DEF LPNIKHYDV DGLPEGYVPSGHPLEPIF FIKAMP+NYK V+ +AV ET K ITC VTDAFYWFGADLA EM+AKWVP+WTAGPH+LLTH +TDLIREK G+ + DD +   FLPGFPEL  SD PEGVI DIDGPF TMLHKMG  LPRATAV+INSFST+H +IENELNS+FKLLLNVGPFILTTPQR +SDEH CLAWLN+ E FSVVYISFGS I+PPPHEL ALAE LEECG PF+W F+GNPEE  P GF ERT+ +GK VAWAPQMEILKHS+VG+CLTHSGWNSVLDCIVGGVPM+SRPFFGDQ++NARM+ES+W IGV V+NGVL+KES +K L L MS+E G+ MR+ I+KLKESAL+AV  NGTSA N +TLI+IVT
Sbjct:   11 MSRDKGESVNVEK-LHVAVLAFPFGTHAGPLLNLARRIAVDAHKVTFSFLCTSRTNAALFSGSKDYDEF-LPNIKHYDVHDGLPEGYVPSGHPLEPIFIFIKAMPDNYKSVMVKAVAETGKNITCLVTDAFYWFGADLAKEMHAKWVPLWTAGPHSLLTHVFTDLIREKIGSKEVDDTKTVDFLPGFPELHVSDFPEGVIGDIDGPFSTMLHKMGLELPRATAVAINSFSTVHPLIENELNSQFKLLLNVGPFILTTPQRMVSDEHGCLAWLNQCEKFSVVYISFGSRIVPPPHELNALAECLEECGCPFIWVFKGNPEETLPNGFTERTKTKGKFVAWAPQMEILKHSAVGMCLTHSGWNSVLDCIVGGVPMVSRPFFGDQRLNARMLESIWGIGVGVDNGVLTKESTMKALNLIMSTEEGKIMREKILKLKESALKAVERNGTSANNFDTLIKIVT 466          

Query:    1 MSNSKGE-INVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSS---DEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNK-DDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            MS  KGE +NV+K LHVAVLAFPFGTHA PL+++ R+IA +A  VTFSF  T ++NA LFS S   DEF LPNIKHYDV DGLPEGYVPSGHPLEPIF FIKAMP+NYK V+ +AV ET K ITC VTDAFYWFGADLA EM+AKWVP+WTAGPH+LLTH +TDLIREK G+ + DD +   FLPGFPEL  SD PEGVI DIDGPF TMLHKMG  LPRATAV+INSFST+H +IENELNS+FKLLLNVGPFILTTPQR +SDEH CLAWLN+ E FSVVYISFGS I+PPPHEL ALAE LEECG PF+W F+GNPEE  P GF ERT+ +GK VAWAPQMEILKHS+VG+CLTHSGWNSVLDCIVGGVPM+SRPFFGDQ++NARM+ES+W IGV V+NGVL+KES +K L L MS+E G+ MR+ I+KLKESAL+AV  NGTSA N +TLI+IVT
Sbjct:    1 MSRDKGESVNVEK-LHVAVLAFPFGTHAGPLLNLARRIAVDAHKVTFSFLCTSRTNAALFSGSKDYDEF-LPNIKHYDVHDGLPEGYVPSGHPLEPIFIFIKAMPDNYKSVMVKAVAETGKNITCLVTDAFYWFGADLAKEMHAKWVPLWTAGPHSLLTHVFTDLIREKIGSKEVDDTKTVDFLPGFPELHVSDFPEGVIGDIDGPFSTMLHKMGLELPRATAVAINSFSTVHPLIENELNSQFKLLLNVGPFILTTPQRMVSDEHGCLAWLNQCEKFSVVYISFGSRIVPPPHELNALAECLEECGCPFIWVFKGNPEETLPNGFTERTKTKGKFVAWAPQMEILKHSAVGMCLTHSGWNSVLDCIVGGVPMVSRPFFGDQRLNARMLESIWGIGVGVDNGVLTKESTMKALNLIMSTEEGKIMREKILKLKESALKAVERNGTSANNFDTLIKIVT 456          

Query:    9 NVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFG-NNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            NV K LHVAVLAFPFGTHAAPL+S+VR+IA EAPN+TFSF ST+K NATLFS   +  +PNIKHY V DGLPEGYVPSG+P EP+F FI AMPE YK  + EAV +T K ITC VTDAFYWF ADLA +M+AKWVP+WTAGPH+LLTH YTDLIRE+ G  N  D +K  FLPGFPEL+A DLPEGVI+D DGPF TMLHKMG  LPRATA++INSF T+H+ IENE+ S FKLLLNVGPFILTTPQ  ISDEH CL WLNKHE+ SVVYISFGSS+ PPPHEL ALAESLEECGFPF+WA RG+P+E+ P+GF ERTR +GKIVAWAPQMEILKHS++GVCLTHSGWNSVLDCIVGGVP+ISRPFFGDQ++N+RM+ES+W+IGV V++GVL+KES +  L+L MSSE+G  MR+N+ KL+ESAL+AV +NG+SAKN  TLIQIVT
Sbjct:   21 NVDK-LHVAVLAFPFGTHAAPLLSLVRRIAGEAPNITFSFLSTRKLNATLFSGPYDEFIPNIKHYSVHDGLPEGYVPSGNPQEPVFMFINAMPEMYKRAMDEAVADTGKNITCLVTDAFYWFAADLAQKMHAKWVPLWTAGPHSLLTHVYTDLIRERIGGTNVRDAQKVDFLPGFPELKACDLPEGVIDDTDGPFATMLHKMGLELPRATAIAINSFETVHTRIENEVGSNFKLLLNVGPFILTTPQNLISDEHGCLEWLNKHENASVVYISFGSSVTPPPHELAALAESLEECGFPFIWALRGDPKEKLPEGFTERTRTQGKIVAWAPQMEILKHSAIGVCLTHSGWNSVLDCIVGGVPIISRPFFGDQRLNSRMLESIWDIGVGVDHGVLTKESTVNALKLIMSSEKGMVMRQNVAKLQESALQAVEQNGSSAKNFLTLIQIVT 465          

Query:    1 MSNSKGEINVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNK-DDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            MS  K E+N    LHVAVLAFPFGTHAAPL+S+V+KIA EAP VTFSFF T  +N TLFS S+EF LPNIK+Y+V DGLP+GYV SG+P EPIF FIKAM EN+K V+ EAV ET K ITC VTDAF+WFGADLA+EM+AKWVP+WTAGPH+LLTH YTDLIREK G+ +  DV+    LPGFPEL+ASDLPEGVI+DID PF TMLHKMG  LPRA AV+INSF+T+H +IENELNSKFKLLLNVGPF LTTPQR +SDEH CL WL++HE+ SVVYISFGS + PPPHEL ALAESLEECGFPF+W+FRG+P+E+ PKGF+ERT+ +GKIVAWAPQ+EILKHSSVGV LTHSGWNSVL+CIVGGVPMISRPFFGDQ +N  + ESV EIGV V+NGVL+KESI K LELTMSSE+G  MR+ IVKLKESA +AV +NGTSA +  TLIQIVT
Sbjct:    1 MSTFKNEMNGNNLLHVAVLAFPFGTHAAPLLSLVKKIATEAPKVTFSFFCTTTTNDTLFSRSNEF-LPNIKYYNVHDGLPKGYVSSGNPREPIFLFIKAMQENFKHVIDEAVAETGKNITCLVTDAFFWFGADLAEEMHAKWVPLWTAGPHSLLTHVYTDLIREKTGSKEVHDVKSIDVLPGFPELKASDLPEGVIKDIDVPFATMLHKMGLELPRANAVAINSFATIHPLIENELNSKFKLLLNVGPFNLTTPQRKVSDEHGCLEWLDQHENSSVVYISFGSVVTPPPHELTALAESLEECGFPFIWSFRGDPKEKLPKGFLERTKTKGKIVAWAPQVEILKHSSVGVFLTHSGWNSVLECIVGGVPMISRPFFGDQGLNTILTESVLEIGVGVDNGVLTKESIKKALELTMSSEKGGIMRQKIVKLKESAFKAVEQNGTSAMDFTTLIQIVT 453          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKAK---FLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFP+GTHAAPL+S+VR+ A E+P V+FSFFSTK+SNA++F+  DE  L NI+ YD+ DGLPE +VPSG+P +P+  F+KAMP NY+  + EAV +T ++ITC V+DAF+WF AD+A+E++AKW+P+WTAGPH LL H  +  IREK G   D V + K   FL GF  L+A DLPEG++E  + PF  ML KMG ALPRATAV+INSFS +HS I  EL S+F +LLNVGPFILTTPQ    D+  CL WLN  E  SVVYISFGS I+PPP EL ALAE+LEE  +PF+WAFRGNP++Q P GF+ERTR +GK+V WAPQM+ILKH++VGVC+TH GWNS+LDCIVGGVPMI RPFFGDQ +N   +E VWEIGV +EN V +KE  ++ LE+ MSSE+G  MR+ +++LK+SA+EA G  G S KN  T   I++
Sbjct:   10 HVAVLAFPYGTHAAPLLSLVRRAAAESPEVSFSFFSTKRSNASVFAGLDEEQLLNIRPYDIEDGLPEDFVPSGNPQDPVAYFVKAMPANYRTAMDEAVAKTGRQITCLVSDAFFWFCADMAEELHAKWIPLWTAGPHPLLAHISSHQIREKLG--PDGVRENKEIDFLTGFNGLKAGDLPEGLVEVPEEPFSMMLDKMGDALPRATAVAINSFSAVHSPIAQELESRFHMLLNVGPFILTTPQSVTLDDEGCLPWLNSQEERSVVYISFGSVIMPPPDELTALAEALEEGRYPFIWAFRGNPDKQLPDGFMERTRMQGKVVGWAPQMQILKHAAVGVCITHGGWNSILDCIVGGVPMICRPFFGDQSLNTATLEHVWEIGVGLENNVFTKEETVRVLEIVMSSEQGMMMREKVLQLKDSAMEAAGPEGDSTKNFCTFADILS 449          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKAK---FLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFP+GTHAAPL+++VR+ A EAP VTFSFFSTK+SNA++F+  +E  L NI+ YD+ DGLPEG+VPSG+P +P+  F+KAMP NY+  + EAV +T ++ITC V+DAF+WF AD+A+EM+AKWVP+WTAGPH LL H  +  IREK G   D V + K   FL GF  L+A DLPEG++E  + PF  ML KMG+ALPRATAV+INSFS +H  I  EL ++F++LLNVGPFILTTPQ    D+  CL WLN  E  SVVYISFGS I+PPP EL A+A++LEE  +PF+WAFRGNPE+Q P GF+ERT+  GK+V WAPQM+ILKHS+VGVC+TH GWNSVLDCIVGGVPMI RPFFGDQ +N   +E VWEIGV +E+ V +KE  L+ LE+ MSSE+G  MR+ +++LK+ A+EA G  G S KN  T   I++
Sbjct:   10 HVAVLAFPYGTHAAPLLNLVRRAAAEAPEVTFSFFSTKRSNASVFAGLNEEQLLNIRPYDIEDGLPEGFVPSGNPQDPVAYFVKAMPANYRTAMNEAVEKTGRQITCLVSDAFFWFCADMAEEMHAKWVPLWTAGPHPLLAHISSQQIREKLG--PDGVRENKEIDFLTGFNGLKAGDLPEGLVEMAEDPFSMMLEKMGEALPRATAVAINSFSAVHIRIGQELETRFQMLLNVGPFILTTPQSVTLDDEGCLPWLNSQEDKSVVYISFGSVIMPPPDELTAIADALEEGKYPFIWAFRGNPEKQLPDGFMERTKTHGKVVGWAPQMQILKHSAVGVCITHGGWNSVLDCIVGGVPMICRPFFGDQSLNTATLEHVWEIGVGLEDNVFTKEETLRVLEIVMSSEKGMMMREKVLELKDLAMEAAGPEGDSTKNFCTFADILS 449          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFG-NNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFP+GTHAAPL+++VR++A EAP VTFSFFSTK+SNA++F+  +E  L NIK Y+V DGLPE YVPS +P + +  F+K+MP NY   + EAV +T + ITC V+DAF+WF ADLADEM+AKWVP+WTAGPH LL H  +  IREK G     + ++  FL GF  L+ASDLP G+ E+ + P   ML KMG+ALPRATAV+INSF+T+H  I +EL S+F  LLNVGPFILTTPQ    DE  CL WLNK E  SVVY+SFGSSI+PPPHEL A+AE+LEE  +PF+WAFRGNPE++ P+GF+ERT  +GK+V WAPQM IL+HS+VGVC+TH GWNSVLDCIVGGVPMISRPFFGDQ +N   +E VWEIGV +ENG+ +KE  L+ LEL MSSE+G+ MR+ + +LK+ A+ A G  G S KN  T  +IVT
Sbjct:   10 HVAVLAFPYGTHAAPLLNLVRRVAAEAPQVTFSFFSTKRSNASVFAGLNEEQLFNIKPYEVDDGLPENYVPSKNPKDAVEFFVKSMPMNYMTSMDEAVAKTGRHITCLVSDAFFWFCADLADEMHAKWVPLWTAGPHPLLAHISSKHIREKLGPEGVRENKEIDFLTGFSGLKASDLPGGLTEEPEDPISMMLEKMGEALPRATAVAINSFATVHLPIAHELESRFHKLLNVGPFILTTPQTVPPDEEGCLPWLNKQEDRSVVYLSFGSSIMPPPHELAAIAEALEEGKYPFIWAFRGNPEKELPQGFLERTNTQGKVVGWAPQMLILRHSAVGVCMTHGGWNSVLDCIVGGVPMISRPFFGDQMLNTATMEHVWEIGVGLENGIFTKEETLRALELIMSSEKGKMMRQKMDELKDFAMAAAGHEGDSTKNFCTFSEIVT 449          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFG-NNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFP+GTHAAPL+++VR++A EAP VTFSFFSTK+SNA++F+  +E  L NIK Y+V DGLPE YVPS +P + +  F+K+MP NY   + EAV +T + ITC V+DAF+WF ADLADEM+AKWVP+WTAGPH LL H  +  IREK G     + ++  FL GF  L+ASDLP G+ E+ + P   ML KMG+ALPRATAV+INSF+T+H  I +EL S+F  LLNVGPFILTTPQ    DE  CL WLNK E  SVVY+SFGSSI+PPPHEL A+AE+LEE  +PF+WAFRGNPE++ P+GF+ERT  +GK+V WAPQM IL+HS+VGVC+TH GWNSVLDCIVGGVPMISRPFFGDQ +N   +E VWEIGV +ENG+ +KE  L+ LEL MSSE+G+ MR+ + +LK+ A+ A G  G S KN  T  +IVT
Sbjct:   10 HVAVLAFPYGTHAAPLLNLVRRVAAEAPQVTFSFFSTKRSNASVFAGLNEEQLFNIKPYEVDDGLPENYVPSKNPKDAVEFFVKSMPMNYMTSMDEAVAKTGRHITCLVSDAFFWFCADLADEMHAKWVPLWTAGPHPLLAHISSKHIREKLGPEGVRENKEIDFLTGFSGLKASDLPGGLTEEPEDPISMMLEKMGEALPRATAVAINSFATVHLPIAHELESRFHKLLNVGPFILTTPQTVPPDEEGCLPWLNKQEDRSVVYLSFGSSIMPPPHELAAIAEALEEGKYPFIWAFRGNPEKELPQGFLERTNTQGKVVGWAPQMLILRHSAVGVCMTHGGWNSVLDCIVGGVPMISRPFFGDQMLNTATMEHVWEIGVGLENGIFTKEETLRALELIMSSEKGKMMRQKMDELKDFAMAAAGHEGDSTKNFCTFSEIVT 449          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNN--KDDVEKAKFLPGFPELEASDLPEGVIEDI-DGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFP+GTHAAPL+++VR+ A EAP V FSFFSTK+SNA++F+  +E  L NIK YDV DGLPE YVPSG+P +PI  FIKA+P NYK  + EAV +T + ITC VTDAFYWF ADLA+E++AKWVP+WTAGPH LL H    LIREK G +  ++D E   FL GF  L AS+LPEG+ E+I D PF  ML KMG+ALPRATAV+INSF+ +H  I  +L SKF ++LN+GPFILT PQ    DE  CL WLNK E  SVVYISFGS I+PPPHELVALAE+LEE   PFLWAFRGNPE+Q P+GF+ERT  +GK+V WAPQM+IL+HS+V +C+ H GWNS+LDCIVGG+PM+SRPFFGDQ +N   +E VW IGV +ENGV +KE  ++ LE   S+E+G+ MR+ I +LK++A+++ G  G S +N      IVT
Sbjct:   10 HVAVLAFPYGTHAAPLLNLVRRTAAEAPEVAFSFFSTKRSNASVFAGLNEEQLLNIKPYDVEDGLPEDYVPSGNPQDPIGYFIKALPGNYKTGINEAVAKTGRNITCLVTDAFYWFCADLAEELHAKWVPLWTAGPHPLLAHISVHLIREKLGPDGVREDKE-VDFLTGFSGLRASNLPEGIAEEIADDPFSNMLEKMGEALPRATAVAINSFTAVHLPIAQDLESKFHMVLNIGPFILTMPQSVTPDEQGCLPWLNKQEGESVVYISFGSVIMPPPHELVALAEALEEGKHPFLWAFRGNPEKQLPQGFLERTSTQGKVVGWAPQMQILRHSAVALCMMHGGWNSILDCIVGGIPMVSRPFFGDQMLNTATLEHVWGIGVGLENGVFAKEDTMRVLESIKSTEKGKIMRQKIEELKDAAMDSAGPEGDSIRNFCVFSDIVT 450          

Query:    1 MSNSKGEINVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNK-DDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            MS  K E+N    LHVAVLAFPFGTHAAPL+S+V+KIA EAP VTFSFF T  +N TLFS S+EF LPNIK+Y+V DGLP+GYV SG+P EPIF FIKAM EN+K V+ EAV ET K ITC VTDAF+WFGADLA+EM+AKWVP+WTAGPH+LLTH YTDLIREK G+ +  DV+    LPGFPEL+ASDLPEGVI+DID PF TMLHKMG  LPRA AV+INSF+T+H +IENELNSKFKLLLNVGPF LTTPQR +SDEH CL WL++HE+ SVVYISFGS + PPPHEL ALAESLEECGFPF+W+FRG+P+E+ PKGF+ERT+ +GKIVAWAPQ+EILKHSSVGV LTHSGWNSVL+CIVGGVPMISRPFFGDQ +N  + ESV EIGV V+NGVL+KESI K LELTMSSE+G  MR+ IVKLKESA +AV +NGTSA +  TLIQIVT
Sbjct:    1 MSTFKNEMNGNNLLHVAVLAFPFGTHAAPLLSLVKKIATEAPKVTFSFFCTTTTNDTLFSRSNEF-LPNIKYYNVHDGLPKGYVSSGNPREPIFLFIKAMQENFKHVIDEAVAETGKNITCLVTDAFFWFGADLAEEMHAKWVPLWTAGPHSLLTHVYTDLIREKTGSKEVHDVKSIDVLPGFPELKASDLPEGVIKDIDVPFATMLHKMGLELPRANAVAINSFATIHPLIENELNSKFKLLLNVGPFNLTTPQRKVSDEHGCLEWLDQHENSSVVYISFGSVVTPPPHELTALAESLEECGFPFIWSFRGDPKEKLPKGFLERTKTKGKIVAWAPQVEILKHSSVGVFLTHSGWNSVLECIVGGVPMISRPFFGDQGLNTILTESVLEIGVGVDNGVLTKESIKKALELTMSSEKGGIMRQKIVKLKESAFKAVEQNGTSAMDFTTLIQIVT 453          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLP-NIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDV---EKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL--TTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIV 452
            HVAVLAFPFGTHAAPL+++ R++A  +P+  FSFF+T +SN++LFSS DE   P NI+ YD+ DG+PEGYV SG P E I  F++A PEN++  + +A  E   ++ C +TDAF+WF AD+A E+NA W+  WTAG ++L  H YTDLIRE  G  +      E    + G  ++   D PEGV+  ++D  F  MLH+MG ALPRATAV INSF  L   + N L S+FK  LN+GP  L  +T Q+ + D H CLAW+ K  S SV YISFG+ + PPP EL A+AE LE    PF+W+ +     Q PKGF++RTR +G +V WAPQ+E+LKH + GV +TH GWNSVL+ + GGVPMI RPFFGDQ++N R +E VWEIG+ + NGV +K+   K L+  +  + G+ M+ N  KLKE A EAV   G S++N   L+  V
Sbjct:   12 HVAVLAFPFGTHAAPLLTVTRRLASASPSTVFSFFNTAQSNSSLFSSGDEADRPANIRVYDIADGVPEGYVFSGRPQEAIELFLQAAPENFRREIAKAETEVGTEVKCLMTDAFFWFAADMATEINASWIAFWTAGANSLSAHLYTDLIRETIGVKEVGERMEETIGVISGMEKIRVKDTPEGVVFGNLDSVFSKMLHQMGLALPRATAVFINSFEDLDPTLTNNLRSRFKRYLNIGPLGLLSSTLQQLVQDPHGCLAWMEKRSSGSVAYISFGTVMTPPPGELAAIAEGLESSKVPFVWSLKEKSLVQLPKGFLDRTREQGIVVPWAPQVELLKHEATGVFVTHCGWNSVLESVSGGVPMICRPFFGDQRLNGRAVEVVWEIGMTIINGVFTKDGFEKCLDKVLVQDDGKKMKCNAKKLKELAYEAVSSKGRSSENFRGLLDAV 456          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFG----NNKDDVEKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVTR 454
            HVAVLAFPF THAAPL+++VR++A  AP+  FSFFST +SNA++F  S      NIK YD+ DG+PEGYV +G P E I  F +A PE+++  +  AV ET + ++C V DAF WF AD+A EM   W+P WTAGP++L TH Y D IREK G      ++D E   F+PG  ++   DL EG++  +++  F  MLH+MGQ LP+ATAV INSF  L   + N+L SK K  LN+GPF L TP   + +   CL WL + +  SVVYISFG+   PPP E+VAL+E+LE    PF+W+ R       P+GF+E+TR  G +V WAPQ E+L H +VG  +TH GWNS+ + + GGVP+I RPFFGDQ++N RM+E V EIGVR+E GV +K  ++   +  +S E+G+ +R+N+  L+E+A  AVG  G+S +N  TL+ +V++
Sbjct:    9 HVAVLAFPFSTHAAPLLAVVRRLAAAAPHAVFSFFSTSQSNASIFHDSMHTMQCNIKSYDISDGVPEGYVFAGRPQEDIELFTRAAPESFRQGMVMAVAETGRPVSCLVADAFIWFAADMAAEMGLAWLPFWTAGPNSLSTHVYIDEIREKIGVSGIQGRED-ELLNFIPGMSKVRFRDLQEGIVFGNLNSLFSRMLHRMGQVLPKATAVFINSFEELDDSLTNDLKSKLKTYLNIGPFNLITPPPVVPNTTGCLQWLKERKPTSVVYISFGTVTTPPPAEVVALSEALEASRVPFIWSLRDKARVHLPEGFLEKTRGYGMVVPWAPQAEVLAHEAVGAFVTHCGWNSLWESVAGGVPLICRPFFGDQRLNGRMVEDVLEIGVRIEGGVFTKSGLMSCFDQILSQEKGKKLRENLRALRETADRAVGPKGSSTENFITLVDLVSK 452          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVW-TAGPHALLTHFYTDLIREKFG---NNKDDVEKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQ-RTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFPF TH  PL+++V+++A EAP+V FSF ST KSN +LFS  +     NIK Y V DG+PEGYV +  P E I  F+K   + +K+ +    +ET ++I   + DAF WF +D+A+E    WVP+W + G  +L  H YTDLIRE  G    +    E  KF+PGF EL   DLP GV+  ++  PF  MLHK+GQALP+AT V INSF  L   +   LNS F   LN+GP  LT+P   + SDE+ C+ WL K  S SV YI FGS   P P E+VA+AE+LE    PFLW+ R   ++  P+GF++RT   GKIV WAPQ+++L HSS+GV +TH GWNSVL+ I GGVPMI RPFFGD  +N  M+E+VW+IGVRVE GV +K S ++ LEL +S E+G+ ++  I  L+E AL+AVG  G+S++N N L++++T
Sbjct:   11 HVAVLAFPFSTHPGPLLNLVQRLAVEAPDVIFSFISTAKSNESLFSVPNP---ENIKPYPVWDGVPEGYVFARKPQEDINLFLKVAAKGFKLAMQAVEVETRRRIGWVMADAFLWFSSDMAEERGISWVPIWMSGGACSLSVHLYTDLIRETVGFSGISGRQNELLKFIPGFSELRLGDLPSGVLLGNLKSPFSIMLHKIGQALPKATTVLINSFEELDPELNKVLNSNFGKFLNIGPSNLTSPHPLSNSDEYGCIPWLAKQRSASVAYIGFGSVAKPKPDEVVAIAEALEASSTPFLWSLRDTSKQYLPEGFLKRTSELGKIVPWAPQVQVLAHSSIGVFITHCGWNSVLETIAGGVPMIGRPFFGDHPINTWMVENVWKIGVRVEGGVFTKSSTMRALELVLSHEKGKKLKDQIGHLRELALKAVGPKGSSSQNFNNLLEVIT 452          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFR-FIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKF---GNNKDDVEKAKFLPGFPELEASDLPEGVIE-DIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTP--QRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSE-RGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            HVAVLAFPF THA  L+ +V+++A   PNVTF+FF+T KSN++LF++    H  NIK +++ DG+PEGYV     +E +   F K+  EN +  +  AV E+ KKITC + DAF WF  ++A+E++  W+P+WT+   +L  H YTDLIRE     G    + E   F+PGF EL    LP GV+  D++ PF  MLHKMG+ + +ATA+ +NSF  L   I  +L SKF   LNVGPF LTTP     I+DE+ C+AWL+K E  SV YI FG+   PPP+EL A+AE+LEE   PFLW+ +   +  FP+GF+ERT   GKIV+WAPQ+++L H SVGV + H GWNSVL+ I  GVP+I RPFFGD ++NA M+E VW+IGV++E GV +K+  +  L+L +S + R   +++ I   KE AL AVG +G+SA+N   L+ I+T
Sbjct:    5 HVAVLAFPFATHAGLLLGLVQRLANALPNVTFTFFNTSKSNSSLFTTP---HDNNIKPFNISDGVPEGYVVGKGGIEALIGLFFKSAKENIQNAMAAAVEESGKKITCVMADAFMWFSGEIAEELSVGWIPLWTSAAGSLSVHVYTDLIRENVEAQGIAGREDEILTFIPGFAELRLGSLPSGVVSGDLESPFSVMLHKMGKTIGKATALPVNSFEELDPPIVEDLKSKFNNFLNVGPFNLTTPPPSANITDEYGCIAWLDKQEPGSVAYIGFGTVATPPPNELKAMAEALEESKTPFLWSLKDLFKSFFPEGFLERTSEYGKIVSWAPQVQVLSHGSVGVFINHCGWNSVLESIAAGVPVICRPFFGDHQLNAWMVEKVWKIGVKIEGGVFTKDGTMLALDLVLSKDKRNTELKQQIGMYKELALNAVGPSGSSAENFKKLVDIIT 448          

Query:    8 INVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDE-FHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNA-KWVPVWTAGPHALLTHFYTDLIREKF-GNNKDDVEKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL---------TTPQRTISDEHD-CLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            ++ Q   HVAVLAFPF THAAPL++IV ++A  AP+  FSFF+TK+SN+++ +S        N+   +V DG+PEGYV  G P E I  F+KA P+N++  +  +V E+ ++++C VTDAF+WFGA +AD+M    WVP WTAGP +L  H +TDLIR    G+  D+ E    + G  ++   DLPEG+I  +++  F  MLH+MG  LP ATAV INSF  L  +I N+L SKFK  LNVGP  L         TTPQ   +   D CL+WL+K ++ SVVY+SFGS   P P EL+ALAE+LE    PFLW+ R N +      F+ + +  G +V WAPQ ++L H SVG  +TH GWNSVL+ + GGVP+I RPFFGDQK+NARM+E VW+IG+R+E GV +K  +LK L++ +S ++G  M+  I  LK+ A +AV   G+S +N  +L+++ T
Sbjct:    4 VSNQAGGHVAVLAFPFSTHAAPLLNIVCRLAAAAPSTLFSFFNTKQSNSSILASDTSVLRYTNVCVCEVADGVPEGYVFVGKPQEDIELFMKAAPDNFRKCLEASVAESGREVSCLVTDAFFWFGAHMADDMGGVPWVPFWTAGPASLSAHVHTDLIRNTTSGDCHDEKETITVIAGMSKVRPQDLPEGIIFGNLESLFSRMLHQMGLMLPLATAVFINSFEELDPVITNDLKSKFKRFLNVGPLDLLEPTASAATTTPQTAEAVAGDGCLSWLDKQKAASVVYVSFGSVTRPSPEELMALAEALEASRVPFLWSLRDNLKNPQLDEFLSKGKLNGMVVPWAPQPQVLAHGSVGAFVTHCGWNSVLESVAGGVPLICRPFFGDQKLNARMVEDVWKIGLRLEGGVFTKNGMLKSLDMLLSQDKGTKMKNKIHTLKQLAQQAVEPKGSSTRNFESLLEMAT 463          

Query:   11 QKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKA---KFLPGFPELEASDLPEGVIE-DIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIV 452
             K+LHVAVLAFPFG+HAAPL+++V ++A   P V FSF ST +SN   F S+      N++ Y+V DG+PEG+  SG+P      F+KA+P N+K  + +A  E+   I C +TDAF+WF  DLA+EM   WVP WTAG  +L  H  TD+IR   G+ +          F+PG   +  +DLP GV+  D++ PF  MLHKMG  LPRATAV +NSF  L   I  +L  + + +L+VGP  L++   +  DE  CL WL+KHE+ SV YISFG+ I PPP+EL+ALAE+L     PFLW+ R +    FP+GF+E   A GK+V+WAPQ ++L H S+GV +TH GWNS+L+ I GGVPMI RPFFGDQ +N+RM++  W IGVR++ GV +K S++  +EL  S E G+ +R+NI+ LK+ A +AVG +G+S +N N L++++
Sbjct:    5 SKALHVAVLAFPFGSHAAPLLALVCRLATSNPTVRFSFLSTAQSNTHTFPSTRTNEFDNVRPYNVWDGVPEGHQISGNPHVGTGFFLKALPHNFKAGMAKAEEESGATINCLLTDAFFWFAGDLAEEMGVPWVPYWTAGACSLSAHVNTDVIRITLGSTRTTQNTNQTLNFIPGLSAVHMNDLPGGVLHGDLESPFAQMLHKMGLNLPRATAVVLNSFEELEPAITTDLKLRLQKVLHVGPPSLSSSPTSSLDESGCLLWLDKHEAASVAYISFGTIITPPPNELLALAEALRASKIPFLWSLRDHSRPIFPEGFLENVLAFGKVVSWAPQSQVLAHPSIGVFVTHCGWNSILESITGGVPMICRPFFGDQTLNSRMVQDAWRIGVRLDGGVFTKSSMMSAVELIFSREEGKKLRENIILLKQKATDAVGASGSSTENFNVLLEVI 450          

Query:    8 INVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDE-FHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNA-KWVPVWTAGPHALLTHFYTDLIREKF-GNNKDDVEKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFILTTPQRTISDE-----------HDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVT 453
            ++ Q   HVAVLAFPF THAAPL++IV ++A  AP+  FSFF+TK+SN+++ + +       N+   +V DG+PEGYV  G P E I  F+KA P+N++  +  +V E+ ++++C VTDAF+WFG  +AD+M    WVP WTAGP +L  H +TDLIR    G   D+ E    + G  ++   DLPEG+I  +++  F  MLH+MGQ  P ATAV INSF  L  +I N+L SKFK  LNVGP  L  P  + +               CL+WL++ +  SVVY+SFGS   P P EL+ALAE+LE    PFLW+ R N + +    F+ + +  G +V WAPQ ++L H SVG  +TH GWNSVL+ + GGVP+I RPFFGDQK+NARM+E VW+IG+R+E GV +K  +LK L++ +S ++G  M+  I  LK+ A +AV   G+SA+N  +L+++ T
Sbjct:    4 VSNQVGGHVAVLAFPFSTHAAPLLNIVCRLAAAAPSTLFSFFNTKQSNSSILAGNTSVLRYSNVSVCEVADGVPEGYVFVGKPQEDIELFMKAAPDNFRRCLEASVAESGREVSCLVTDAFFWFGVHMADDMGGVPWVPFWTAGPASLSAHVHTDLIRSTTSGGCHDEKETITVIAGMSKVRPQDLPEGIIFGNLESLFSRMLHQMGQMPPLATAVFINSFEELDPVITNDLKSKFKRFLNVGPLDLLEPPASAATTTPQTAAEAVAGDGCLSWLDEQKVASVVYVSFGSVTRPSPEELMALAEALEASRVPFLWSLRDNLKNRQLDEFLSKGKLNGMVVPWAPQPQVLAHGSVGAFVTHCGWNSVLESVAGGVPLICRPFFGDQKLNARMVEDVWKIGLRLEGGVFTKNGMLKSLDMLLSQDKGTKMKNKINTLKQFAKQAVEPKGSSARNFESLLEMTT 464          

Query:   15 HVAVLAF-PFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKA-KFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL--TTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVTR 454
            HVAVLAF P G HA PL+++ R++A  +P+  FSFF+T +SNA+LFSS    H  NIK +DV DG+PEG +  G+PLE +  F++A P  ++  +  A IE  KK+TC +TDAF+WF AD+A E+NA WV  W  G ++L  H YTDLIRE  G     +E+   F+PG       D+PE V+ ED+D  F   L++M  ALPRA+AV I+SF  L   +   L SK K  LN+ P  L  +T ++ + D H C AW+ K  + SV YISFG+ + PPP ELVA+A+ LE    PF+W+ +       PKGF++RTR +G +V WAPQ+E+LKH ++GV +TH GWNSVL+ +  GVPMI RP   D ++N R +E VW++GV ++NGV +KE   K L      + G+ M+ N  KLKE   E     G+S +N   L+  + +
Sbjct:   12 HVAVLAFFPVGAHAGPLLAVTRRLAAASPSTIFSFFNTARSNASLFSSD---HPENIKVHDVSDGVPEGTM-LGNPLEMVELFLEAAPRIFRSEIAAAEIEVGKKVTCMLTDAFFWFAADIAAELNATWVAFWAGGANSLCAHLYTDLIRETIGLKDVSMEETLGFIPGMENYRVKDIPEEVVFEDLDSVFPKALYQMSLALPRASAVFISSFEELEPTLNYNLRSKLKRFLNIAPLTLLSSTSEKEMRDPHGCFAWMGKRSAASVAYISFGTVMEPPPEELVAIAQGLESSKVPFVWSLKEKNMVHLPKGFLDRTREQGIVVPWAPQVELLKHEAMGVNVTHCGWNSVLESVSAGVPMIGRPILADNRLNGRAVEVVWKVGVMMDNGVFTKEGFEKCLNDVFVHDDGKTMKANAKKLKEKLQEDFSMKGSSLENFKILLDEIVK 452          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHL-PNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKAK----FLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKL-LLNVGPFILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLI 449
            HVAVLAFPFGTHAAPL+++V ++A  AP++ FSFFST  S  T+FS ++   +  NIK Y V DG PEG+V SG+P EPI  F+ A P+N+   + +AV +T   I+C +TDAF WF AD ++++   W+PVWTA   +L  H YTD IR +F    D  EKA+    F+PG   +  SDLPE +I ED    F   LH MG  L +ATAV++NSF  +  II N L S  +L +LN+GP + T       ++++CL WL   +  SVVY+SFG+ I PPP+E+ ALA +LE    PFLW+ R    +  P+ FI+RT   GKIV+WAPQ+ +L++ ++GV +TH GWNS L+ I   VP+I RPFFGDQK+NARM+E VW+IGV V+ GV +++   + LEL + S++G+ MR+N+ +LKE A +AV  NG+S +N  +L+
Sbjct:    6 HVAVLAFPFGTHAAPLLTLVNRLAASAPDIIFSFFSTSSSITTIFSPTNLISIGSNIKPYAVWDGSPEGFVFSGNPREPIEYFLNAAPDNFDKAMKKAVEDTGVNISCLLTDAFLWFAADFSEKIGVPWIPVWTAASCSLCLHVYTDEIRSRFAE-FDIAEKAEKTIDFIPGLSAISFSDLPEELIMEDSQSIFALTLHNMGLKLHKATAVAVNSFEEIDPIITNHLRSTNQLNILNIGP-LQTLSSSIPPEDNECLKWLQTQKESSVVYLSFGTVINPPPNEMAALASTLESRKIPFLWSLRDEARKHLPENFIDRTSTFGKIVSWAPQLHVLENPAIGVFVTHCGWNSTLESIFCRVPVIGRPFFGDQKVNARMVEDVWKIGVGVKGGVFTEDETTRVLELVLFSDKGKEMRQNVGRLKEKAKDAVKANGSSTRNFESLL 445          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLP-NIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDV---EKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL--TTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIV 452
            HVAVLAFPFGTHAAPL+++ R++A  +P+  FSFF+T +SN++LFSS DE   P NI+ YD+ DG+PEGYV SG P E I  F++A PEN++  + +A  E   ++ C +TDAF+WF AD+A E+NA W+  WTAG ++L  H YTDLIRE  G  +      E    + G  ++   D PEGV+  ++D  F  MLH+MG ALPRATAV INSF  L   + N L S+FK  LN+GP  L  +T Q+ + D H CLAW+ K  S SV YISFG+ + PPP EL A+AE LE    PF+W+ +     Q PKGF++RTR +G +V WAPQ+E+LKH + GV +TH GWNSVL+ + GGVPMI RPFFGDQ++N R +E VWEIG+ + NGV +K+   K L+  +  + G+ M+ N  KLKE A EAV   G S++N   L+  V
Sbjct:   12 HVAVLAFPFGTHAAPLLTVTRRLASASPSTVFSFFNTAQSNSSLFSSGDEADRPANIRVYDIADGVPEGYVFSGRPQEAIELFLQAAPENFRREIAKAETEVGTEVKCLMTDAFFWFAADMATEINASWIAFWTAGANSLSAHLYTDLIRETIGVKEVGERMEETIGVISGMEKIRVKDTPEGVVFGNLDSVFSKMLHQMGLALPRATAVFINSFEDLDPTLTNNLRSRFKRYLNIGPLGLLSSTLQQLVQDPHGCLAWMEKRSSGSVAYISFGTVMTPPPGELAAIAEGLESSKVPFVWSLKEKSLVQLPKGFLDRTREQGIVVPWAPQVELLKHEATGVFVTHCGWNSVLESVSGGVPMICRPFFGDQRLNGRAVEVVWEIGMTIINGVFTKDGFEKCLDKVLVQDDGKKMKCNAKKLKELAYEAVSSKGRSSENFRGLLDAV 456          

Query:   15 HVAVLAF-PFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKA-KFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL--TTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVTR 454
            HVAVLAF P G HA PL+++ R++A  +P+  FSFF+T +SNA+LFSS    H  NIK +DV DG+PEG +  G+PLE +  F++A P  ++  +  A IE  KK+TC +TDAF+WF AD+A E+NA WV  W  G ++L  H YTDLIRE  G     +E+   F+PG       D+PE V+ ED+D  F   L++M  ALPRA+AV I+SF  L   +   L SK K  LN+ P  L  +T ++ + D H C AW+ K  + SV YISFG+ + PPP ELVA+A+ LE    PF+W+ +       PKGF++RTR +G +V WAPQ+E+LKH ++GV +TH GWNSVL+ +  GVPMI RP   D ++N R +E VW++GV ++NGV +KE   K L      + G+ M+ N  KLKE   E     G+S +N   L+  + +
Sbjct:   12 HVAVLAFFPVGAHAGPLLAVTRRLAAASPSTIFSFFNTARSNASLFSSD---HPENIKVHDVSDGVPEGTM-LGNPLEMVELFLEAAPRIFRSEIAAAEIEVGKKVTCMLTDAFFWFAADIAAELNATWVAFWAGGANSLCAHLYTDLIRETIGLKDVSMEETLGFIPGMENYRVKDIPEEVVFEDLDSVFPKALYQMSLALPRASAVFISSFEELEPTLNYNLRSKLKRFLNIAPLTLLSSTSEKEMRDPHGCFAWMGKRSAASVAYISFGTVMEPPPEELVAIAQGLESSKVPFVWSLKEKNMVHLPKGFLDRTREQGIVVPWAPQVELLKHEAMGVNVTHCGWNSVLESVSAGVPMIGRPILADNRLNGRAVEVVWKVGVMMDNGVFTKEGFEKCLNDVFVHDDGKTMKANAKKLKEKLQEDFSMKGSSLENFKILLDEIVK 452          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLP-NIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLAD-EMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDV---EKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPF-ILTTPQRT---ISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIV 452
            HVAVL FPFGTHAAPL+++  ++A  AP+  FSFFST +SN++L SS     +P NI+ ++V DG+PEG+V +G+P   +  F++A PE ++  +  A  E  +K  C +TDAF W  A+ A  EM A WV  +  G  +L  H YTD IRE  G  +      E   F+ G  ++   D  EGV+  ++D  F   LH+MG ALPRATAV INSF  L     N+  S+FK  LN+GP  +L++P +T   + D H CLAW+ K  + SV YI+FG    PPP ELVA+A+ LE    PF+W+ +       P+GF++RTR +G +V WAPQ+E+L H ++GV ++H GWNSVL+ +  GVPMI RP FGD  +NAR +E+VWEIGV + +GV +K+   + L+  +  + G+ M+ N  KL+E A EAV   G+S +N   L+  V
Sbjct:   12 HVAVLVFPFGTHAAPLLAVTCRLATAAPSTVFSFFSTARSNSSLLSSD----IPTNIRVHNVDDGVPEGFVLTGNPQHAVELFLEAAPEIFRREIKAAETEVGRKFKCILTDAFLWLAAETAAAEMKASWVAYYGGGATSLTAHLYTDAIRENVGVKEVGERMEETIGFISGMEKIRVKDTQEGVVFGNLDSVFSKTLHQMGLALPRATAVFINSFEELDPTFTNDFRSEFKRYLNIGPLALLSSPSQTSTLVHDPHGCLAWIEKRSTASVAYIAFGRVATPPPVELVAIAQGLESSKVPFVWSLQEMKMTHLPEGFLDRTREQGMVVPWAPQVELLNHEAMGVFVSHGGWNSVLESVSAGVPMICRPIFGDHAINARSVEAVWEIGVTISSGVFTKDGFEESLDRVLVQDDGKKMKVNAKKLEELAQEAVSTKGSSFENFGGLLDEV 455          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKAKFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL--TTPQRT--ISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVTR 454
            HVAVLAFPFG+H   ++++ R++A  AP+  FSF +T +SN +L SS      PNI+ +DV DG+PEGYV S +P E +  F++A PE ++  +  A  E  +K+TC +TDAF WF  D+A EM   WV  WT+G  +LL    T +  EK   +K   E    + G  ++   D PEGV+  ++D  F  MLH+MG ALPRAT V +NSF  L   + + L  KFK  L++GP  L  +T QR   + D H CLAW+ K  + SVVYI+FG  + PPP ELV +A+ LE    PF+W+ +       PKGF++ TR +G +V WAPQ+E+L H ++GV ++H GWNSVL+ +  GVPMI RP FGD  +NAR +E+VWEIG+ + +GV +K+   + L+  +  + G+ M+ N  KLKE A EAV   G+S +N   L+  V +
Sbjct:    5 HVAVLAFPFGSHGQAILAVTRRLATAAPSTVFSFLNTSQSNFSLLSSDLP---PNIRVHDVSDGVPEGYVLSRNPQEAVELFLEAAPEIFRRELAVAETEVGRKVTCMLTDAFIWFAGDMAAEMKVSWVAFWTSGTRSLL--ISTQISSEKQSLSK---ETLGCISGMEKIRVKDTPEGVVFGNLDSVFSKMLHQMGLALPRATTVYMNSFEELDPTLTDNLRLKFKRYLSIGPLALLFSTSQRETPLHDPHGCLAWIKKRSTASVVYIAFGRVMTPPPGELVVVAQGLESSKVPFVWSLQEKNMVHLPKGFLDGTREQGMVVPWAPQVELLNHEAMGVFVSHGGWNSVLESVSAGVPMICRPIFGDHALNARSVEAVWEIGMTISSGVFTKDGFEESLDRVLVQDDGKKMKFNAKKLKELAQEAVSTEGSSFENFKGLLDEVMK 441          

Query:  151 HALLTHFYTDLIREKFGNNKDDVEKA-KFLPGFPELEASDLPEGVI-EDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFIL--TTPQRT--ISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIVTR 454
            ++L  H YTDLIRE        +E+    + G  ++   D PEGV+  ++D  F  MLH+MG ALPRAT V +NSF  L   + + L  KFK  L++GP  L  +T QR   + D H CLAW+ K  + SVVYI+FG  + PPP ELV +A+ LE    PF+W+ +       PKGF++ TR +G +V WAPQ+E+L H ++GV ++H GWNSVL+ +  GVPMI RP FGD  +NAR +E+VWEIG+ + +GV +K+   + L+  +  + G+ M+ N  KLKE A EAV   G+S +N   L+  V +
Sbjct:   30 NSLTAHLYTDLIRETIAVKDGRMEETLGCISGMEKIRVKDTPEGVVFGNLDSVFSKMLHQMGLALPRATTVYMNSFEELDPTLTDNLRLKFKRYLSIGPLALLFSTSQRETPLHDPHGCLAWIKKRSTASVVYIAFGRVMTPPPGELVVVAQGLESSKVPFVWSLQEKNMVHLPKGFLDGTREQGMVVPWAPQVELLNHEAMGVFVSHGGWNSVLESVSAGVPMICRPIFGDHALNARSVEAVWEIGMTISSGVFTKDGFEESLDRVLVQDDGKKMKFNAKKLKELAQEAVSTEGSSFENFKGLLDEVMK 339          

Query:   12 KSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIE-TEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREK--FGNNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQAL--PRATAVSINSFSTLHSIIENELNSKFKL-LLNVGPFILTT--PQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNP------EEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLI 449
            K   + ++  P   H  P++ + + +  +  ++T     + +      SSS +F   +     +P  L E  + +  P + + +  +    ++K  +G+ + E     I C V D + +F      E     V   T    A +       +  +    + KD   + K  PG   L   DLP  V     GP  + L    + +    A+AV INS S L S     L  + ++ +  +GP  +T   P   + ++  C+ WLNK +S SV+YIS GS  +    +++ +A  L     PFLW  R          E  P+ F      RG IV WAPQME+L+H +VG   +H GWNS ++ I  GVPMI RPF GDQK+NAR +E VW IGV++E G L KE++ + +E  +  E G  MRK  + LKE    +V   G+S  +L+  +
Sbjct:    7 KETRIVLVPVPAQGHVTPMMQLGKALHSKGFSITVVLTQSNR-----VSSSKDFS--DFHFLTIPGSLTESDLQNLGPQKFVLKLNQICEASFKQCIGQLLHEQCNNDIACVVYDEYMYFSHAAVKEFQLPSVVFSTTSATAFVCRSVLSRVNAESFLIDMKDPETQDKVFPGLHPLRYKDLPTSVF----GPIESTLKVYSETVNTRTASAVIINSASCLESSSLARLQQQLQVPVYPIGPLHITASAPSSLLEEDRSCVEWLNKQKSNSVIYISLGSLALMDTKDMLEMAWGLSNSNQPFLWVVRPGSIPGSEWTESLPEEFNRLVSERGYIVKWAPQMEVLRHPAVGGFWSHCGWNSTVESIGEGVPMICRPFTGDQKVNARYLERVWRIGVQLE-GDLDKETVERAVEWLLVDEEGAEMRKRAIDLKEKIETSVRSGGSSCSSLDDFV 446          

Query:    7 EINVQKSLHVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREK--FGNNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQA--LPRATAVSINSFSTLHSIIENELNSKFKL-LLNVGPFIL--TTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNP------EEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLI 449
            E+ V++   + ++  P   H  P++ + + +  +  ++T       +      SSS +F   +     +P  L E  + +  P + +F+  +    ++K  +G+ + E    I C V D + +F      E     V   T    A +       +  +    + KD     K  PG   L   DLP        GP  ++L    +   +  A+AV INS S L S     L  + ++ +  +GP  +  + P   + ++  CL WLNK +  SV+YIS GS  +    +++ +A  L     PFLW  R          E  P+ F      RG IV WAPQ+E+L+H +VG   +H GWNS L+ I  GVPMI RPF GDQK+NAR +E VW IGV++E G L K ++ + +E  +  E G  MRK ++ LKE    +V   G+S  +L+  +
Sbjct:    3 ELGVKR--RIVLVPVPAQGHVTPIMQLGKALYSKGFSITVVLTQYNR-----VSSSKDFS--DFHFLTIPGSLTESDLKNLGPFKFLFKLNQICEASFKQCIGQLLQEQGNDIACVVYDEYMYFSQAAVKEFQLPSVLFSTTSATAFVCRSVLSRVNAESFLLDMKDPKVSDKEFPGLHPLRYKDLPTSAF----GPLESILKVYSETVNIRTASAVIINSTSCLESSSLAWLQKQLQVPVYPIGPLHIAASAPSSLLEEDRSCLEWLNKQKIGSVIYISLGSLALMETKDMLEMAWGLRNSNQPFLWVIRPGSIPGSEWTESLPEEFSRLVSERGYIVKWAPQIEVLRHPAVGGFWSHCGWNSTLESIGEGVPMICRPFTGDQKVNARYLERVWRIGVQLE-GELDKGTVERAVERLIMDEEGAEMRKRVINLKEKLQASVKSRGSSFSSLDNFV 444          

Query:   16 VAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAV---IETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFGNNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKL-LLNVGPF---ILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFR------GNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIV 452
            + +  FP   H  P+  +         N+ F+   +     T F+S +  + P+     +PD L E   P  +P   +   +  +        G+ +   I  E    C + DA ++F  DL ++ N   + + T    A +      ++REK   +  + +    +P  P L   DLP    ED        +  M ++L  ++ +  N+   L +   +E   +F + L  +GPF   +  +    ++ +  CL+WL+K  + SV+Y S GS       E + +A  L     PFLW  R          E  PKGFIE    RGKIV WAPQ E+L H + G  LTH GWNS L+ I   +PMI RP FGDQ++NAR I  VW+IG+ +EN V  +  I   +   M+S  G  +RK I+ +KE+  + +   G+S +NL  LI  +
Sbjct:   10 IFLFPFPLQGHLNPMFQLA--------NIFFNRGFSITVIHTEFNSPNSSNFPHFTFVSIPDSLSE---PESYP--DVIEILHDLNSKCVAPFGDCLKKLISEEPTAACVIVDALWYFTHDLTEKFNFPRIVLRTVNLSAFVAFSKFHVLREKGYLSLQETKADSPVPELPYLRMKDLPWFQTEDPRSGDKLQIGVM-KSLKSSSGIIFNAIEDLETDQLDEARIEFPVPLFCIGPFHRYVSASSSSLLAHDMTCLSWLDKQATNSVIYASLGSIASIDESEFLEIAWGLRNSNQPFLWVVRPGLIHGKEWIEILPKGFIENLEGRGKIVKWAPQPEVLAHRATGGFLTHCGWNSTLEGICEAIPMICRPSFGDQRVNARYINDVWKIGLHLENKV-ERLVIENAVRTLMTSSEGEEIRKRIMPMKETVEQCLKLGGSSFRNLENLIAYI 444          

Query:   16 VAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKSNATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHA-----LLTHFYTDLIREKFGNNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGPFGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLL--LNVGPF--ILTTPQRTISDEHDCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPE------EQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVENGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQIV 452
            V ++ FP   H +P++ + + +  +  ++T       ++    FS SD+F   + +   +P+ LPE    +  P++ +F+  K    ++K  +G+ V++   +I+C + D F +F    A E     +   T    A     +    Y + ++      K   E+   +P F  L   D P      ++       + + +    A++V IN+ S L S   + L  +   +    +GP   + + P   + +   C+ WLNK +  SV+YIS GS  +   +E++ +A  L      FLW  R          E  P+ F +    RG IV WAPQ E+L H +VG   +H GWNS L+ I  GVPMI RPF GDQK+NAR +E VW+IG++VE G L +  + + ++  M  E G  MRK    LKE    +V   G+S  +L   +  +
Sbjct:   15 VVLVPFPAQGHISPMMQLAKTLHLKGFSIT-----VVQTKFNYFSPSDDF-THDFQFVTIPESLPESDFKNLGPIQFLFKLNKECKVSFKDCLGQLVLQQSNEISCVIYDEFMYFAEAAAKECKLPNIIFSTTSATAFACRSVFDKLYANNVQAPLKETKGQQEE--LVPEFYPLRYKDFPVSRFASLESIMEVYRNTVDKR--TASSVIINTASCLESSSLSFLQQQQLQIPVYPIGPLHMVASAPTSLLEENKSCIEWLNKQKVNSVIYISMGSIALMEINEIMEVASGLAASNQHFLWVIRPGSIPGSEWIESMPEEFSKMVLDRGYIVKWAPQKEVLSHPAVGGFWSHCGWNSTLESIGQGVPMICRPFSGDQKVNARYLECVWKIGIQVE-GELDRGVVERAVKRLMVDEEGEEMRKRAFSLKEQLRASVKSGGSSHNSLEEFVHFI 455          

Query:   15 HVAVLAFPFGTHAAPLVSIVRKIAEEAPNVTFSFFSTKKS--------NATLFSSSDEFHLPNIKHYDVPDGLPEGYVPSGHPLEPIFRFIKAMPENYKIVVGEAVIETEKKITCFVTDAFYWFGADLADEMNAKWVPVWTAGPHALLTHFYTDLIREKFG--NNKDDVEKAKFLPGFPELEASDLPEGVIEDIDGP--FGTMLHKMGQALPRATAVSINSFSTLHSIIENELNSKFKLLLNVGPFI--LTTPQRTISDEH-----------DCLAWLNKHESFSVVYISFGSSIIPPPHELVALAESLEECGFPFLWAFRGNPEEQFPKGFIERTRARGKIVAWAPQMEILKHSSVGVCLTHSGWNSVLDCIVGGVPMISRPFFGDQKMNARMIESVWEIGVRVE---NGVLSKESILKGLELTMSSERGRFMRKNIVKLKESALEAVGENGTSAKNLNTLIQI 451
            H+ VL FP   H  P+    +++A +   +T    S K S        + T+F  S+ F        D+ D +        + L  +   +K      + +V ++ +        ++ D  + +G   A      W          L+T  Y  + +  F   + K         P FP L A+DLP  + E    P     ++ ++   + R   V  N+F  L   +   + S + +L N+GP +  +   +R   D++           +C+ WLN  E  SVVY+SFGS +I    +++ LA  L++ G  FLW  R     + P+ ++E    +G IV+W+PQ+++L H S+G  LTH GWNS L+ +  GVPMI  P + DQ  NA+ ++ VW++GVRV+   +G + +E I++ +E  M  E+G+ +RKN  K K  A EAV E G+S K++N  + +
Sbjct:    6 HLIVLPFPGQGHITPMSQFCKRLASKGLKLTLVLVSDKPSPPYKTEHDSITVFPISNGFQEGEEPLQDLDDYMERVETSIKNTLPKLVEDMKLSGNPPRAIVYDSTMP-------WLLDVAHSYGLSGAVFFTQPW----------LVTAIYYHVFKGSFSVPSTKYGHSTLASFPSFPMLTANDLPSFLCESSSYPNILRIVVDQLSN-IDRVDIVLCNTFDKLEEKLLKWVQSLWPVL-NIGPTVPSMYLDKRLSEDKNYGFSLFNAKVAECMEWLNSKEPNSVVYLSFGSLVILKEDQMLELAAGLKQSGRFFLWVVRETETHKLPRNYVEEIGEKGLIVSWSPQLDVLAHKSIGCFLTHCGWNSTLEGLSLGVPMIGMPHWTDQPTNAKFMQDVWKVGVRVKAEGDGFVRREEIMRSVEEVMEGEKGKEIRKNAEKWKVLAQEAVSEGGSSDKSINEFVSM 451