Vfaba.Hedin2.R1.3g193040.1

Query:    3 NSTYFIWWVLCIV---PL----IHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCP-------KQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSVSTDSL 582
            +ST +IWW+LC++   PL    IH LTPQSPIQCNQTICTL+NSYGTWNDRK CYALNVTYPT E++LRLAV++VVQNNLKAK+VTKFSHTIP LSCP         N   N AF ISTEKY+SGI+IDA NL VTVDSGV L  LID+VEKNGFSL  VPYWEGV++GGV+S+GAHGSSWWGKGGAFH+ VL I +VVP SKSEGYAK+LRL+ + PL  AAKVSLGVLGAISKVKLSIE RFKRSIT+NFTDDTDIEN+YI+HAKKYEFADITWY SR+TAVYRYDFRVPLN SGDG +DFIGFQAN I I ESVRGAEKLLEN  ++KGKCLTA+TTL FKKLTANGLKNNG IFTGYPVIGYQGKMQTSGSCLYS++ DTSCAWDPRIKGLFFYESTAIFPASKF DFI DVKKLRDI+P+ FCGID YNGILIRYIKAS+AYLG  EDSIVIDFNYYRAND FTPRLNQDVWEELEQ+AFFKYGAKPHWAKNRNLAFLGVQ+KYPKFN FI+AK ++DPQ+VFSGDWSDEILYGK+ +K+DGCALEG CICSEDRHCSPQKGY C +GLVY EARVCR  STS S DSL
Sbjct:    4 SSTNWIWWILCVIHTLPLFIKTIHGLTPQSPIQCNQTICTLQNSYGTWNDRKICYALNVTYPTNEEELRLAVSYVVQNNLKAKVVTKFSHTIPKLSCPLQQQNIINNNNNVNSAFLISTEKYNSGIEIDAKNLFVTVDSGVGLRPLIDEVEKNGFSLGGVPYWEGVSVGGVISTGAHGSSWWGKGGAFHDHVLGINLVVPASKSEGYAKVLRLEPNDPLLKAAKVSLGVLGAISKVKLSIEPRFKRSITYNFTDDTDIENIYIDHAKKYEFADITWYPSRNTAVYRYDFRVPLNTSGDGHFDFIGFQANPIFISESVRGAEKLLENMRSTKGKCLTAATTLGFKKLTANGLKNNGLIFTGYPVIGYQGKMQTSGSCLYSTKSDTSCAWDPRIKGLFFYESTAIFPASKFKDFIIDVKKLRDIDPQKFCGIDIYNGILIRYIKASDAYLGQIEDSIVIDFNYYRANDPFTPRLNQDVWEELEQLAFFKYGAKPHWAKNRNLAFLGVQKKYPKFNLFIEAKNKLDPQSVFSGDWSDEILYGKDSIKYDGCALEGQCICSEDRHCSPQKGYYCKNGLVYNEARVCRYSSTSASLDSL 597          

Query:    5 TYFIWWVLCIV---------PLI---HSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSVSTDSL 582
            +++IWW++ ++         PLI   H+ TPQSP+QCNQ+ CTL+NSYG W DRK CYALN+TYPTTE+QLRLAV++ VQNNLK K+VTK SHTIP L+CP+  T   +   ISTEKYDSGIQIDA NLAVT DSGV L  LID VE  GFSLV  PYWEGV+IGG++S+GAHGSSWWGKGGA H+ VL + V+VP S+SE YAKIL L+   PLFNAAKVSLGVLGAISKVKLS+EHRFKRSI++NFTDD  IE+VYI HAK+YEFADITWY S+HTAVYRYD RVPL+ASG+G+YDFIGFQANSILI ESVR AE LLENT +  GKCLTA+TTL +KKL  NGLKNNG IFTGYPV+G+QGKMQTSGSCLYS+R DT+CAWDPRIKGLFFYESTAIFPAS+FG+FI+DV+KLRD+NP+NFCG+DNYNGILIR+IKAS+AYLG SEDS+VIDFNYYRAND  TPRLN+DVWEE+EQ+AFFKYGAKPHWAKNRNLAFLGVQ KYPKFN FI  K ++DPQ+VFS  WS+EILYGKE  KFDGCALEG+CICSEDRHCSPQ GY C  GLVYKEARVCR  S+S++T S+
Sbjct:    3 SFWIWWIVAVIHILPFYDSNPLIQTIHARTPQSPVQCNQSGCTLQNSYGAWGDRKDCYALNITYPTTEEQLRLAVSYAVQNNLKVKVVTKLSHTIPKLACPEGKT---NTLLISTEKYDSGIQIDAANLAVTADSGVGLRALIDAVESAGFSLVAAPYWEGVSIGGLISTGAHGSSWWGKGGAVHDHVLGLKVIVPASESERYAKILWLEALDPLFNAAKVSLGVLGAISKVKLSLEHRFKRSISYNFTDDAHIEDVYINHAKQYEFADITWYPSKHTAVYRYDSRVPLDASGNGIYDFIGFQANSILISESVRAAENLLENTKSVNGKCLTAATTLEYKKLVGNGLKNNGLIFTGYPVVGHQGKMQTSGSCLYSTRFDTACAWDPRIKGLFFYESTAIFPASRFGNFIRDVRKLRDLNPENFCGVDNYNGILIRFIKASDAYLGQSEDSVVIDFNYYRANDALTPRLNEDVWEEVEQLAFFKYGAKPHWAKNRNLAFLGVQHKYPKFNQFIAIKHKLDPQSVFSSTWSEEILYGKESEKFDGCALEGLCICSEDRHCSPQMGYYCRQGLVYKEARVCR-YSSSITTTSI 588          

Query:    1 MSNSTYFIWWVL---------CIVPLIHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSVS 578
            + +  Y++ W L         C++  +H   PQSP++C+ + CTL NSYG W DRK C ALNVTYPTTE+QLRLAV++ V+NNLKAK+VT+FSHTIP L+CP+    NN    ISTEKYDSGIQIDA N+AVT D+GV L +LID VE +GFSLV  PYWEGVT+ G++S+GAHGSSWWGKGGA H+ +L I++VVP SKSEGYAKILR +   PL NAAK+SLGVLGAISKVKLS+E+RFKRSIT+NFT+D +IE+VY++HAK+YEFADITWY SRHTAVYRYD R+PLNASGDGV DFIGFQANSILI ESVR AEKLLE+T N+ GKCLTA TTL FKKL  NGLKNNGQIFTGYPV+GYQGKMQTSGSCLYS+   T+CAWDPRI GLFFYESTAIFPAS+FGDFI+DV+KLRD+ P+NFCGIDNYNG+LIR+IKAS AYLG  EDS+VIDFNYYRAN+   PRLNQDVWEE+EQ+AFFKYGAKPHWAKNRN+AFLGVQ+KYPKFN FI AK+++DPQNVFS  WSD+ILYGKE  KFDGCALEG+CICSEDRHCSPQ GY C HGL+YKEARVCR L +S++
Sbjct:   32 LMDGGYWLCWFLGVIHAVQFTCLIKTVHGKIPQSPVECSSSGCTLRNSYGAWGDRKDCSALNVTYPTTEEQLRLAVSYAVRNNLKAKVVTRFSHTIPKLACPQ---GNNATLLISTEKYDSGIQIDAANMAVTADAGVGLRQLIDAVEGSGFSLVAAPYWEGVTVAGLISTGAHGSSWWGKGGAVHDHLLGISIVVPASKSEGYAKILRFEAQDPLLNAAKLSLGVLGAISKVKLSLEYRFKRSITYNFTEDNNIEDVYVDHAKQYEFADITWYPSRHTAVYRYDSRIPLNASGDGVNDFIGFQANSILISESVRAAEKLLESTRNAIGKCLTADTTLGFKKLVGNGLKNNGQIFTGYPVVGYQGKMQTSGSCLYSTNFGTACAWDPRINGLFFYESTAIFPASRFGDFIRDVRKLRDLKPENFCGIDNYNGLLIRFIKASSAYLGQPEDSVVIDFNYYRANNPSNPRLNQDVWEEVEQLAFFKYGAKPHWAKNRNIAFLGVQQKYPKFNMFIGAKQKLDPQNVFSSKWSDDILYGKESEKFDGCALEGLCICSEDRHCSPQNGYYCRHGLIYKEARVCRYLPSSIA 615          

Query:    5 TYFIWWVLCIV---------PLI---HSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCR 571
            +Y+IWW++ ++         PLI   H+ TPQSP+QC+Q+ CTL+NSYG W DRK C ALN+TYPTTE++ RLAV+  VQNNLK K+VTKFSHTIP L+CP+     N++  ISTEKYDSGIQIDA NLAVT DSGV L  LID VE  GFSLV  PYWEGV+IGG++S+GAHGSSWWGKGGA H+ VL ++++VP S+SEGYAKILRL+   PLFNAA+VSLGVL AISKVKLS+E RFKRSIT+NFTDD  IE+VY +HAK+YEFADITWY S++T+VYRYD RVPLNASGDGVYDFIGFQANSILI +SVR AEKLLEN  N KGKCLTA+TTL FKKL  NGLKNN  +FTGYPV+GYQGKMQTSGSCLYS++ DT+CAWDPRIKGLFFYESTAIFPASKFGDFI+DV+KLRD+NP+NFCGIDNYNGILIR+IKAS+AYLG SEDS+VIDFNYYRAND   PRLNQDVWEE+EQ+AFFKYGAKPHWAKNR LAFLGVQ+KYPKF+ FI AK+Q+DPQ+VFS  WS+EILYG E  KFDGCALEG+CICSED+HCSPQ GY C  GL+YKEARVCR
Sbjct:    3 SYWIWWIIAVIHILPIFDSNPLIQTIHARTPQSPVQCDQSGCTLQNSYGAWGDRKDCNALNITYPTTEEEFRLAVSQAVQNNLKVKVVTKFSHTIPKLACPE---GKNNSLLISTEKYDSGIQIDAANLAVTADSGVGLRALIDAVESAGFSLVAAPYWEGVSIGGLISTGAHGSSWWGKGGAVHDHVLGLSIIVPASESEGYAKILRLEAQDPLFNAARVSLGVLCAISKVKLSLEPRFKRSITYNFTDDAHIEDVYTDHAKQYEFADITWYPSKNTSVYRYDSRVPLNASGDGVYDFIGFQANSILISKSVRAAEKLLENAKNVKGKCLTAATTLGFKKLMGNGLKNNALLFTGYPVVGYQGKMQTSGSCLYSTKFDTACAWDPRIKGLFFYESTAIFPASKFGDFIQDVRKLRDLNPENFCGIDNYNGILIRFIKASDAYLGQSEDSVVIDFNYYRANDASAPRLNQDVWEEVEQLAFFKYGAKPHWAKNRKLAFLGVQKKYPKFDQFIAAKQQLDPQSVFSSTWSEEILYGNESEKFDGCALEGLCICSEDKHCSPQMGYYCKEGLIYKEARVCR 578          

Query:    4 STYFIWWVLCIV----PLI---HSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCR 571
            S+Y IWW++ ++    PLI   H+ TPQSP+QCN++ CTL+NSYG W DRK C ALN+TYPTTE++ RLAV++ VQNNLK K+VTKFSHTIP L+CP+   T      ISTEKY S IQIDA NLAVT DSGV L  LID VE  GFSLV  PYWEGV+IGG++S+GAHGSSWWGKGGA H+ VL ++++VP S+SEGYAKILRL+   PLFNAAKVSLGVLGAISKVKLS+E RFKRSIT+NFTDD +IE+V+ +HAK+YEFADITWY S++TAVYRYD RVPLNASGDG+YDFIGFQANSILI ESVRGAEKLLEN  N  GKCLTA+TTLAFKKLT NGLKNNG +FTGYPV+GYQGK+QTSGSCLYS++ D SCAWDPRIKGLFFYESTA FPASKFGDFI+DV+KLRD+ P+NFCGIDNYNGILIR+IKAS+AYLG +EDS+VIDFNYYRAND  TPRLNQDVWEE+EQ+AFFKYGAKPHWAKNR LAFL VQ+KYPKFN FI AK+Q+DPQ+VFS  WSDEIL GKE  KFDGCALEG CIC+ED+HCSPQ GY C  GL+Y +ARVCR
Sbjct:    3 SSYCIWWIIAVIHISNPLIQTIHAKTPQSPVQCNESGCTLQNSYGAWGDRKDCIALNITYPTTEEEFRLAVSNAVQNNLKVKVVTKFSHTIPKLACPEGKNT----LLISTEKYGSDIQIDAANLAVTADSGVGLRALIDAVENAGFSLVAAPYWEGVSIGGLISTGAHGSSWWGKGGAVHDHVLGLSLIVPASQSEGYAKILRLEAQDPLFNAAKVSLGVLGAISKVKLSLEPRFKRSITYNFTDDANIEDVFTDHAKQYEFADITWYPSKNTAVYRYDSRVPLNASGDGIYDFIGFQANSILISESVRGAEKLLENAKNVNGKCLTAATTLAFKKLTGNGLKNNGMLFTGYPVVGYQGKIQTSGSCLYSTKFDNSCAWDPRIKGLFFYESTAFFPASKFGDFIRDVRKLRDLKPENFCGIDNYNGILIRFIKASDAYLGQAEDSVVIDFNYYRANDASTPRLNQDVWEEVEQLAFFKYGAKPHWAKNRKLAFLDVQKKYPKFNQFIAAKQQLDPQSVFSSTWSDEILNGKESEKFDGCALEGQCICTEDKHCSPQNGYYCKQGLIYTDARVCR 573          

Query:    5 TYFIWWVLCIV---------PLI---HSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCR 571
            +++IWW++ ++         PLI   H+ TPQSPIQCN++ CTL+NSYG W DRK CYAL++TYPTTE+QLRLAV+H VQN LK K+VTKFSHTIP L+CP+     N+   ISTEKYDSGIQIDA NLAVT DSGV L  LID VE  GFSLV  PYWEGV+IGG++S+GAHGSSWWGKGGA H+ VL ++++VP S+SEGYAKIL L+  +PL NAAKVSLGVLGAISKVKLS+E RFKRSIT+NFTDD +IE+VYI+HAK+YEFADITWY S++TAVYRYD RVPL+ASG+G+YDFIGFQANSILI +SVR AEKLLE+  +  GKCLTA+TTL +KKL  NGLKNNG IFTGYPV+GYQGKMQTSGSCLYS+R DT+CAWDPRI GLFFYESTAIFPASKFGDFI+DV+KLRD+ P+NFCGIDNYNGILIR+IKAS AYLG SEDS+VIDFNYYRAND  TPRLNQDVWEE+EQ+AFFKYGAKPHWAKNRN+AFLGVQ KYPKF+ FI  K ++DPQ+VFS  WS+EILYGKE  K+DGCALEG+CICSED+HCSPQ GY C  GLVYKEARVCR
Sbjct:    3 SFWIWWIIAVIHILPLFDSNPLIQTIHAKTPQSPIQCNESGCTLQNSYGAWGDRKDCYALDITYPTTEEQLRLAVSHAVQNKLKVKVVTKFSHTIPKLACPE---GKNNTLLISTEKYDSGIQIDAANLAVTADSGVGLRSLIDAVESEGFSLVAAPYWEGVSIGGLISTGAHGSSWWGKGGAVHDHVLGLSLIVPASESEGYAKILWLEAQNPLLNAAKVSLGVLGAISKVKLSLEPRFKRSITYNFTDDANIEDVYIDHAKQYEFADITWYPSKNTAVYRYDSRVPLDASGNGIYDFIGFQANSILISKSVRVAEKLLESAKSVNGKCLTAATTLGYKKLVGNGLKNNGLIFTGYPVVGYQGKMQTSGSCLYSTRFDTACAWDPRINGLFFYESTAIFPASKFGDFIRDVRKLRDLKPENFCGIDNYNGILIRFIKASNAYLGQSEDSVVIDFNYYRANDASTPRLNQDVWEEVEQLAFFKYGAKPHWAKNRNIAFLGVQHKYPKFDQFIATKHKLDPQSVFSSTWSEEILYGKESEKYDGCALEGLCICSEDKHCSPQMGYYCRQGLVYKEARVCR 578          

Query:   12 LCIVPLIHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTD-IENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSVSTDSLL 583
            LC +  +H   PQSP++C+ + C L NSYG W DR+ C A+NVTYPTTE+QLR AV++ V+NNLK K+VTKFSHTIP L+CP+   +      ISTEKYDSGI+IDA N+AVT D+GV L +LID VE  GFSLV  PYWEGVT+ GV+S+GAHGSSWWGKGG+ H+ V+ ITVVVPGS+SEGYAK+LRL+   P+ NAAK+SLGVLGAISKVKLSIEHR KRSIT+NFT+  D IE+VY+EHAKKYEFADITWY SRHT VYRYD RVPLNASGDG+ DFIGFQ NSILI ESVR AEKLLE T N+ GKCLTA+TTL FKKL  NGLKNNG++F+GYPV+GYQGKMQTSGSCLYS+R DTSCAWDPRIKGLFFYESTAIFPAS FGDFI+DV+KLRD+ P+NFCG+DNYNG+LIR+IKAS AYLG  EDS+V+DFNYYRAND   PRLNQDVWEELEQ+AFFKYGAKPHWAKNR +AFLGVQ KYPKF+ FI AK++MDPQNVFS +WSD +LYGKE  K DGCALEG+CICSEDRHCSPQKG+ C+HGLVYKEARVCR L +S+S  S +
Sbjct:   21 LCSITTVHGKVPQSPVECSSSGCILRNSYGAWGDRRDCSAINVTYPTTEEQLRSAVSYAVRNNLKVKVVTKFSHTIPKLACPQ---SAGATLLISTEKYDSGIEIDAVNMAVTADAGVGLRQLIDAVESEGFSLVAAPYWEGVTVAGVISTGAHGSSWWGKGGSVHDHVVGITVVVPGSRSEGYAKVLRLEAQDPMLNAAKLSLGVLGAISKVKLSIEHRLKRSITYNFTEKEDLIEDVYVEHAKKYEFADITWYPSRHTVVYRYDSRVPLNASGDGLNDFIGFQPNSILISESVRAAEKLLERTRNANGKCLTAATTLGFKKLVGNGLKNNGRMFSGYPVVGYQGKMQTSGSCLYSTRFDTSCAWDPRIKGLFFYESTAIFPASAFGDFIRDVRKLRDLKPENFCGVDNYNGLLIRFIKASSAYLGQHEDSVVVDFNYYRANDPSDPRLNQDVWEELEQLAFFKYGAKPHWAKNRKVAFLGVQHKYPKFDMFIAAKQKMDPQNVFSSEWSDAVLYGKEAEKVDGCALEGLCICSEDRHCSPQKGFYCSHGLVYKEARVCRYLQSSMSPSSTI 590          

Query:   21 LTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSVSTDS 581
            + P+SP+QC  + CTL NSYG W DRK C ALNVTYPTTE QLR AV++ V+NNLKAK+VT FSHTIP L+CP+     N   FIST+KY+S IQIDA NL VTVD+GV L +LID VE  GFSLV  PYWEGVT+ G++S+GAHGSSWWG+GGA H+ V+ IT+VVP SKSEGYAK+LRLD   PL NAAKVSLGVLGAISKVKLS+EHRFKRSIT+NFT D  IE+VY EHAK+YEFADITWY SRHTAVYRYD RVP+NASGDG+ DFIGFQ N ILI ESVR AEKLLE+T N  GKCLTA+TTL FKKL  NGLKNNG IF+GYPV+G+QGKMQTSGSCLYS+R+DTSCAWDPRIKG FFYESTAIFPASKFGDF++DV+KLRD+NP+NFCG+DNYNG+LIR+IKAS AYLG  EDS+V+DFNYYRAND   PRLNQDVWEE+EQ+AFFK+GAKPHWAKNRN+AFLGVQ+KYP+FN F+ AK++MDPQNVFS  WSD+ILYGKEL KFDGCALEG CICSED+HCSPQKGYLC+ GLVYKEARVCR L +S+ + S
Sbjct:    1 MIPRSPLQCTASGCTLSNSYGAWGDRKDCSALNVTYPTTEDQLRSAVSYAVRNNLKAKVVTGFSHTIPKLACPQ-----NATVFISTDKYNSTIQIDAVNLVVTVDAGVGLRQLIDAVEAKGFSLVAAPYWEGVTVAGLISTGAHGSSWWGRGGAVHDYVIGITLVVPASKSEGYAKVLRLDAQDPLLNAAKVSLGVLGAISKVKLSLEHRFKRSITYNFTGDDGIEDVYTEHAKQYEFADITWYPSRHTAVYRYDSRVPINASGDGLNDFIGFQPNPILISESVRAAEKLLESTKNPNGKCLTAATTLGFKKLAGNGLKNNGMIFSGYPVVGFQGKMQTSGSCLYSTRIDTSCAWDPRIKGFFFYESTAIFPASKFGDFVRDVRKLRDLNPQNFCGVDNYNGLLIRFIKASSAYLGQPEDSVVVDFNYYRANDPSDPRLNQDVWEEVEQLAFFKHGAKPHWAKNRNIAFLGVQQKYPRFNMFVAAKQKMDPQNVFSSKWSDDILYGKELEKFDGCALEGQCICSEDKHCSPQKGYLCSPGLVYKEARVCRYLPSSIPSSS 556          

Query:   12 LCIVPLIHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNT--TNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTD-IENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCR 571
            LC +  ++ + PQSP++C+ + C L NSYG W DR+ C ALNVTYPTTE+QLR AV++ V+NNLK K+VTKFSHTIP L+CP+ ++  +      ISTEKYDSGI+IDA N+AVT D+GV L +LID VE  GFSLV  PYWEGVT+ GV+S+GAHGSSWWGKGG+ H+ VL IT+VVP S+SEGYAK+LRL+   P+ NAAK+SLGVLGAISKVKLSIEHRFKRSI ++F++  D IE+VY+EHAKKYEFADITWY SRHT VYRYD RVPLNASGDGV DFIGFQ NSILI ESVR AEKLLE+T N+ GKCLTA+TTL FK+   NGLKNNGQIF+GYPV+GYQG MQTSGSCLYS+R DTSCAWDPRIKGLFFYESTAIFPAS FGDF++DV+KLRD+ P+NFCG+DNYNG+LIR+IKAS AYLG  EDS+V+DFNYYRAND   PRLNQD+ EE+EQ+AFFKYGAKPHWAKNRN+AFLGVQ KYPKF+ FI AK++MDPQNVFS +WSD ILYGKE  K DGCALEG+CICSEDRHCSPQKG+ C+HGLVY EARVCR
Sbjct:   42 LCSITTVYGMVPQSPVECSSSGCILRNSYGAWGDRRDCSALNVTYPTTEEQLRSAVSYAVRNNLKVKVVTKFSHTIPKLACPQGSSRASAGATLLISTEKYDSGIEIDAANMAVTADAGVGLRQLIDAVETGGFSLVAAPYWEGVTVAGVISTGAHGSSWWGKGGSVHDHVLAITLVVPASRSEGYAKVLRLEAQDPMLNAAKLSLGVLGAISKVKLSIEHRFKRSIRYDFSEKDDAIEDVYVEHAKKYEFADITWYPSRHTVVYRYDSRVPLNASGDGVNDFIGFQPNSILISESVRAAEKLLESTRNTNGKCLTAATTLGFKRFVGNGLKNNGQIFSGYPVVGYQGTMQTSGSCLYSTRFDTSCAWDPRIKGLFFYESTAIFPASAFGDFVRDVRKLRDLKPENFCGVDNYNGLLIRFIKASSAYLGQPEDSVVVDFNYYRANDPSNPRLNQDLLEEVEQLAFFKYGAKPHWAKNRNVAFLGVQHKYPKFDMFIAAKQKMDPQNVFSSEWSDAILYGKESEKVDGCALEGLCICSEDRHCSPQKGFYCSHGLVYNEARVCR 604          

Query:   12 LCIVPLIHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNT--TNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTD-IENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCR 571
            LC +  ++ + PQSP++C+ + C L NSYG W DR+ C ALNVTYPTTE+QLR AV++ V+NNLK K+VTKFSHTIP L+CP+ ++  +      ISTEKYDSGI+IDA N+AVT D+GV L +LID VE  GFSLV  PYWEGVT+ GV+S+GAHGSSWWGKGG+ H+ VL IT+VVP S+SEGYAK+LRL+   P+ NAAK+SLGVLGAISKVKLSIEHRFKRSI +NF++  D IE+VY EHAKKYEFADITWY SRHT VYRYD RVPLNASGDG+ DFIGFQ NSI+I ESVR AEKLLE+T N  GKCLTA+TTL FK+L  NGLKNNGQIF+GYPV+GYQGKMQTSGSCLYS+R DTSCAWDPRIKGLFFYESTAIFP+S FGDF++DV+KLRD+ P+NFCG+DNYNG+LIR+IKAS AYLG  EDS+V+DFNYYRAND   PRLNQD+ EE+EQ+AFFKYGAKPHWAKNRN+AFLGVQ KYPKF+ FI AK++MDPQNVFS +WSD ILYGKE  K DGCALEG+CICSEDRHCSPQKG+ C+HGLVY EARVCR
Sbjct:   42 LCSITTVYGMVPQSPVECSSSGCILRNSYGAWGDRRDCSALNVTYPTTEEQLRSAVSYAVRNNLKVKVVTKFSHTIPKLACPQGSSRASAGATILISTEKYDSGIEIDAANMAVTADAGVGLRQLIDVVESRGFSLVAAPYWEGVTVAGVISTGAHGSSWWGKGGSVHDHVLAITLVVPASRSEGYAKVLRLEAQDPMLNAAKLSLGVLGAISKVKLSIEHRFKRSIRYNFSEKDDVIEDVYAEHAKKYEFADITWYPSRHTVVYRYDSRVPLNASGDGLNDFIGFQPNSIVISESVRAAEKLLESTRNVNGKCLTAATTLGFKRLVGNGLKNNGQIFSGYPVVGYQGKMQTSGSCLYSTRFDTSCAWDPRIKGLFFYESTAIFPSSAFGDFVRDVRKLRDLKPENFCGVDNYNGLLIRFIKASSAYLGQPEDSVVVDFNYYRANDPSNPRLNQDLLEEVEQLAFFKYGAKPHWAKNRNVAFLGVQHKYPKFDMFIAAKQKMDPQNVFSSEWSDAILYGKESEKVDGCALEGLCICSEDRHCSPQKGFYCSHGLVYMEARVCR 604          

Query:   18 IHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHH--PLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSS--RVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKY-PKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSV 577
            + S+ PQ PI+C+QT CT+ N+YGTW DRKTC+A NVTYPTTE+ LR AVA+  ++NLK K VTKFSHTIP L+CP    + + A  IST KY+S I+I+ + L VT DSGV L ELI++VE  GFS+   PYWEGV+IGG++S+G+HGSSW G+GG+ H+ V+ I++VVP ++SEG+AK++RL+E     L NA KVSLGVLG ISKVKLSIE  FKRS+T+NFT D  +E++++EH KKYEF DITWY SR TAVYRYD R P+N SG+GV DF+GFQ+N ILI + VR  EK  E++ N  GKC TA TTLA+KKL  NGLKN+G IFTGYPVIG QGK+QTSGSCLYSS  R+D +CAWDPR  GLFFYE+TAIFP S+F DF+ DVKKLRD+ P+  CGID YNGI IR+IK S+AYLG +EDS+VIDFNYYRA+D+ TPRLNQDV EE+EQMAF K+GAKPHW KNR + F GV++K  P F+ F++ K ++DP+ +FS +WSDEIL G E  K+DGCALEG C+CSE+RHC+P KGY C  GLVY +ARVCR     V
Sbjct:   22 VQSVPPQPPIRCDQTGCTVSNAYGTWPDRKTCHAANVTYPTTEEDLRKAVAYAAEHNLKVKTVTKFSHTIPKLACP----SGSDALLISTSKYNSVIEIEPELLTVTADSGVSLRELIEKVEGAGFSIGTSPYWEGVSIGGLISTGSHGSSWSGRGGSVHDHVVGISLVVPANQSEGFAKVVRLEEGRDDTLLNAVKVSLGVLGVISKVKLSIEKAFKRSVTYNFTSDVALEDIFMEHGKKYEFGDITWYPSRKTAVYRYDIRAPVNVSGNGVNDFLGFQSNPILISKGVRALEKGFESSKNENGKCTTADTTLAYKKLIGNGLKNSGLIFTGYPVIGRQGKIQTSGSCLYSSSIRIDVACAWDPRYNGLFFYETTAIFPVSRFRDFLLDVKKLRDMKPERLCGIDIYNGIFIRFIKGSKAYLGQTEDSVVIDFNYYRADDELTPRLNQDVMEEMEQMAFVKHGAKPHWGKNRKVGFFGVKQKIGPNFDKFLEVKNKLDPKKMFSSEWSDEILLGTEASKYDGCALEGNCVCSEERHCNPSKGYFCKEGLVYTQARVCRFSPAQV 582          

Query:   13 CIVPLIHSLT---PQSPIQC--NQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPL--FNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCL--YSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEIL--YGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
            C+  L+H++    P+ P++C    T C + NS G + DR TC A NV YPTTE +L   VA   +   K ++ T++SH+IP L+C    T  N   FIST+  +  +Q DA  + +TV+SGV L +LI +  K G +L   PYW GVT+GG++ +GAHGSS WGKG A H+ V EI +V PGS ++G+AKI  L E      FNAAKVSLGVLG IS+V   ++  FKRS+ +   +D D  +  +   KK+EFAD  W  S+   VYR D RV +N  G+G+YDF  F++    +  + R +E+  E   ++ GKC+TA+T  +    T+ GL NNG  FTGYPVIG Q +M +SGSCL     ++ ++CAWD R+KG+F++++T   P ++   FI D+K L  I+ K+ CG++ Y GIL+RY+ +S AYLG   ++I  D  YYRAND  TPRL +D  EE+EQ+A  KY A PHW KNRNLAF GV +KY    AF+  K+  DP  +FS +W+D+IL   G   +  DGCALEG+CICS+D HC+P KGYLC  G VYKEARVC
Sbjct:   21 CLFTLVHTVISTPPEDPVKCVSGNTNCIVTNSLGAFPDRSTCRAANVAYPTTEAELVSIVAAATKAGRKMRVTTRYSHSIPKLTC----TDGNDGLFISTKFLNHTVQADAKAMTLTVESGVTLRQLIAEAAKVGLALPYAPYWWGVTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRMVSPGSVNDGFAKIRVLSETTTPNEFNAAKVSLGVLGVISQVTFELQPMFKRSLKYVMRNDLDFNDEALTFGKKHEFADFVWLPSQGKVVYRMDDRVAVNTLGNGLYDFFPFRSQLSAVLATTRSSEETQETLRDAHGKCVTATTISSTLFSTSYGLTNNGITFTGYPVIGSQNRMMSSGSCLDGLEDKLTSACAWDSRVKGVFYHQTTFSIPLTQVKSFINDIKSLLKIDSKSLCGLELYYGILMRYVTSSPAYLGKETEAIDFDITYYRANDPLTPRLYEDFIEEIEQIALLKYNALPHWGKNRNLAFDGVIKKYKNAPAFLKVKESYDPNGLFSSEWTDQILGIKGNPTIVKDGCALEGLCICSDDAHCAPSKGYLCRPGKVYKEARVC 585          

Query:    8 IWWVLCIVPLIHSLTPQSPIQC--NQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPL--FNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEIL--YGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
            ++++  ++    S  P  P++C    T CT+ NSYG + DR TC A NV YP TE +L   VA   Q   K ++ T++SH+I  L C    T      FIST+  +  +Q DA  + +TV+SG+ L +LI +  K G +L   PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PGS +EG+AKI  L E      FNAAKVSLGVLG IS+V   ++  FKRS+T+   +D+D E+  +   KK+EFAD  W  S+   VYR D RV +N SG+G++DF+ F++        +R +E+  E   ++ GKC+ A+   +     + GL NNG IFTGYPV+G Q +M +SGSCL S +  + T+CAWD RIKG FF+++T   P ++   FI D+K L  I  K+ CG++ + GIL+RY+ +S AYLG   +++  D  YYRA D  TPRL +D  EE+EQ+A FKY A PHW KNRNLAF GV  KY    AF+  K   DP+ +FS +W+D+IL   G   +  DGCALEG+CICS+D HC+P KGYLC  G VYKEARVC
Sbjct:   15 LYYIFTLMHTAVSTPPDDPVKCVSGNTNCTVTNSYGAFPDRSTCRAANVAYPKTEAELVSVVAAATQAGRKMRVTTRYSHSITKLVC----TDGTEGLFISTKFLNHTVQADATAMTMTVESGMTLRQLIVEAAKVGLALPYAPYWWGLTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRMVSPGSVNEGFAKIRILSETTTPNEFNAAKVSLGVLGVISQVTFELQPMFKRSLTYTMRNDSDFEDQAVTFGKKHEFADFIWLPSQGKVVYRRDDRVAVNTSGNGLFDFLPFRSQLSAAIAIIRTSEETQERFRDANGKCVGATIISSTLFAPSYGLTNNGIIFTGYPVVGSQNRMMSSGSCLDSLQDGLITACAWDSRIKGEFFHQTTLSVPLTQVKSFISDIKSLVKIEQKSLCGLELHYGILMRYVTSSPAYLGKETEALDFDITYYRAKDPLTPRLYEDFIEEIEQIALFKYNALPHWGKNRNLAFDGVIRKYNNAPAFLKVKDSYDPKGLFSSEWTDQILGIKGNASIVKDGCALEGLCICSKDAHCAPAKGYLCRPGKVYKEARVC 581          

Query:    8 IWWVLCIVPLIH---SLTPQSPIQC--NQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKI--LRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEIL--YGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
            I+ V CI  L+    S  P+ P++C    T CT+ NSYG + DR TC A NV YPTTE +L   VA   +   K ++ T++SH+I  L+C    T       IST+  +  ++ DA  + +TV+SGV L +LI +  K G +L   PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PGS ++G+AK+  LR       FNAAKVSLGVLG IS+V L ++  FKRS+ +   +D+D  +  +    K+EFAD  W  S+   VYR D RV +N SG+G+ DF+ F++        +R +E+  E   ++ GKC  A+   +    T+ GL NNG IFTGYPVIG Q +M +SGSCL S    + T+C WD RIK  FF+++T   P ++   FI D+K L  I  K+ C ++ Y+GIL+RY+ +S AYLG   +++  D  YYRA D  +PRL +D  EE+EQ+A FKY A PHW KNRNLAF GV +KY    AF+  K+  DP  +FS +W+D+IL   G   +  DGCALEG+C+CSED HC+P KGY C  G VYKEARVC
Sbjct:   20 IFVVHCISTLVFTTISTPPEDPVKCVSGNTNCTVTNSYGAFPDRSTCRAANVAYPTTEAELISVVAAATKAGRKMRVTTRYSHSITKLAC----TDGTDGLLISTKFLNHTVRTDATAMTLTVESGVTLRQLIAEAAKVGLALPYAPYWWGLTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRIVSPGSVNDGFAKVRVLRETTTPKEFNAAKVSLGVLGVISQVTLKLQPMFKRSLRYVMRNDSDFGDQAVTFGMKHEFADFIWLPSQGKVVYRMDDRVAVNTSGNGLLDFMPFRSQLSAALAIIRSSEETQERFRDANGKCAGATLITSTLFATSYGLTNNGMIFTGYPVIGSQNRMMSSGSCLDSLHDGLITACPWDSRIKSEFFHQTTFSIPLTQVKSFINDIKSLVKIESKSLCVLELYDGILMRYVTSSPAYLGKETEALDFDLTYYRAKDPLSPRLYEDFIEEIEQIALFKYNALPHWGKNRNLAFDGVIKKYKNVPAFLKVKESYDPMGLFSSEWTDQILGIKGNVTIIKDGCALEGLCVCSEDAHCAPTKGYFCRPGKVYKEARVC 589          

Query:    5 TYFIWWVLCIVPLIHSLTPQSPIQCN--QTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDE--HHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVD---TSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRA-NDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEI--LYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLST 575
            ++++  + C      S  P  P+ C    T+CT+ NSYG + DR  C A  V YP TE +L   VA   +   K ++VT++SH+ P L C    T       IST+  +  +  + +   +TV+SGV L +LI++  K   +L   PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PG  S+GY K+  L E      F AAKVSLGVLG IS+V   ++  FKRS+ +   +D+D  +  +   +++EFAD  W  S+   VYR D RVPLN SGDG+++F  F++   L+    R  E+  E+  ++  KC+ A    +   L + G+ NNG IFTGYPVIG Q  M +SGSCL  SR D   T+C WDPRIKG FF+++T     +    FI D+K L  I PK+ C ++  NGILIRY+ +S A+LG  E ++  D  YYR+ ND   PRL +D  EE+EQMA FKY A PHW KNRNLAF G   KY   NAF+  K++ D   +FS +W+D+I  L G   +   GCALEG+CICSED HC+P KGYLC  G VY+EARVC  +S+
Sbjct:    2 SFWLSLIFCFFTFASSSPPDDPVNCEFGNTMCTVTNSYGAFPDRSICKAAKVEYPRTEAELVSIVAAATRAGQKMRVVTRYSHSFPKLVC----TDGKDGTLISTKFLNHVVTTNPEAKTLTVESGVTLRQLIEEAAKFDLALPYAPYWWGLTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRLVSPGLASDGYVKVQVLSETIDPEEFRAAKVSLGVLGVISQVTFELQPMFKRSLNYVMRNDSDFGDQAVSFGERHEFADFLWLPSQGKVVYRMDGRVPLNTSGDGLFEFFPFRSQLSLVLAIDRSLEESEESLEDANMKCVRAKLVSSSMFLMSYGVTNNGLIFTGYPVIGMQNHMMSSGSCL-DSRQDGLITACPWDPRIKGQFFHQTTFSVSLTNVKSFINDIKALVKIEPKSLCVLEGSNGILIRYVTSSLAFLGKEEKALDFDLTYYRSKNDPLAPRLYEDYIEEIEQMAIFKYNALPHWGKNRNLAFDGAIRKYKNANAFLKVKEKFDSLGLFSTEWTDQILGLKGNVTIVKQGCALEGLCICSEDSHCAPTKGYLCRPGKVYREARVCTRVSS 577          

Query:   12 LCIVPLIHSLTPQSPIQCNQ--TICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDE--HHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRA-NDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEI--LYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
             C      S  P  P++C     +CT+ NSYG + DR  C A  V YP TE +L   VA   +   K ++VT++ H+IP L C    T       IST+  ++ +  + +   +TV+SGV L +LI +  +   +L + PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PG  S+GY K+  L E      F AAKVSLGVLG IS+V   ++  FKRS+TF   +D+D  +  +   +K+EFAD  W  S+   VYR D RVP+N SG+G++DF  F+    +    +R  E+  E++G++  KC  A    +F    + G+ NNG  FTGYPVIG Q  M +SG+CL S +  + TSC WDPRIKG FF+++    P ++   FI D+K L  I PK+ C ++  NGILIRY+ +S A+LG  E ++  D  YYR+ +D   PRL +D  EE+EQMA FKY A PHW KNRNLAF GV  KY   N F+  K++ DP  +FS +W+++I  L G   +  +GCALEG+C+CS+D HC+P+KGYLC  G VY +ARVC
Sbjct:   10 FCFCTFASSTPPDDPVKCESGNNMCTVTNSYGAFPDRSICEAAKVEYPKTEAELVSIVAAATRAGQKVRVVTRYVHSIPKLVC----TDGKDGVLISTKFLNNVVGTNPEAKTLTVESGVTLRQLIGEAAELELALPHAPYWWGLTVGGLMGTGAHGSSLWGKGSAVHDYVSEIRMVSPGLASDGYVKVRVLSETIDPDEFRAAKVSLGVLGVISQVTFQLQPMFKRSLTFVMQNDSDFGDQAVTFGEKHEFADFLWLPSQGKVVYRMDDRVPVNTSGNGLFDFFPFRPQLSVALAIIRSLEESEESSGDANDKCARAEQITSFLFSISYGVTNNGMEFTGYPVIGKQNHMMSSGTCLDSHQDGLITSCPWDPRIKGQFFHQTAFSIPLTRVKGFINDIKALVKIEPKSLCALERSNGILIRYVTSSPAFLGKEEKALDFDLTYYRSKDDPLAPRLYEDFIEEIEQMAIFKYNALPHWGKNRNLAFDGVIRKYKNANTFLKVKERFDPLGLFSTEWTNQILGLKGNVTIVKEGCALEGLCVCSDDAHCAPKKGYLCRPGKVYTKARVC 573          

Query:  345 IFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRA-NDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEI--LYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLS 574
            IFTGYPVIG Q ++ +SG+CL S +  + TSC WDPRIKG FFY++    P +   DFI D+K L  I PK+ CG++   G+L+RY+ +S AYL   E ++  D  YYR+ +D +TPRL +D  EE+EQMA  KY A PHW KNRNLAF G  +KY   N F+  K+++DP  +FS +W+D+I  L G   +   GCA EG+CICS+D HC+P KGY+C  G VYKEARVC L++
Sbjct:   17 IFTGYPVIGSQDRIMSSGACLDSHQNGLITSCPWDPRIKGEFFYQTALSVPLTHVKDFINDIKALVKIEPKSLCGLELNYGVLVRYVTSSPAYLRKEEKALDFDLTYYRSKDDPWTPRLYEDYMEEIEQMAILKYNALPHWGKNRNLAFDGAIKKYKNANTFLKVKERLDPWGLFSTEWTDQILGLKGNVTIVKQGCAPEGLCICSDDSHCAPNKGYMCRPGKVYKEARVCTLVT 251          

Query:   40 YGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFK-RSITFNFTDDTDIENVYIEHAKKYEFADITWYASRH--TAVYRYDFRVPLNASGDGVYDF-IGFQANSIL--IPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGP--SEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILY 526
            +  W     C       PT+ +++R  +A   Q N + K+V    H+   ++C          F I   K +  +++D +   VTV++G+ L +L  Q++K+G +L N+     VT GGV+ SG H +    K G    QV+E+T++ P    +G   +     +  +F AA+V LG LG I  V L    +F  +  TF  T    ++N+   H KK E+    W+      + +Y+     P ++S +  +D+ IGF     L  I   V G               L       F  L  NG K N  +   + +  Y+        C +   V                +  AI P  K  + + ++K + + +PK    +  +  + +R+ +A +  L P    DS  ++   YR   +  PRL  D W   E +   K G +PHWAK  N      ++ YP F  F   ++++DP  +F   + +++ Y
Sbjct:   10 FQNWAKTYGCCPEMYYQPTSVEEIREVLALARQQNKRVKVVGG-GHSPSDIAC-------TDGFMIHMGKMNRVLKVDMEKKQVTVEAGILLADLHPQLDKHGLALSNLGAVSDVTAGGVIGSGTHNTGI--KHGILATQVVELTLLTP----DGTVLVCSESSNAEVFQAARVHLGCLGVILTVTLQCVPQFHLQETTFPSTLKEVLDNL-DSHLKKSEYFRFLWFPHSENVSVIYQDHTNKPPSSSANWFWDYAIGFYLLEFLLWISTFVPG---------------LVGWINRFFFWLLFNGKKENCNL--SHKIFTYE--------CRFKQHV----------------QDWAI-PREKTKEALLELKAMLEAHPK----VVAHYPVEVRFTRADDILLSPCFQRDSCYMNIIMYRPYGKDVPRL--DYWLAYETI-MKKVGGRPHWAKAHNCTRKDFEKMYPAFRKFCAIREKLDPTGMFLNAYLEKVFY 440          

Query:   57 PTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDE--HHPLFNAAKVSLGVLGAISKVKLSIEHRFK-RSITFNFTDDTDIENVYIEHAKKYEFADITWYASRH--TAVYRYDFRVPLNASGDGVYDF-IGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGP--SEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILY 526
            PT+ +++R  +A   Q N + K+V    H+   ++C          F I   K +  +++D +   VTV++G+ L +L  Q++K+G +L N+     VT GGV+ SG H +    K G    QV+ +T++           IL   E  +  +F AA+V LG LG I  V L    +F  +  TF  T    ++N+   H KK E+    W+      + +Y+     P ++S +  +D+ IGF              E LL  +    G  L       F  L  NG K N  +   + +  Y+        C +   V                +  AI P  K  + + ++K + + NPK    +  +  + +R+ +  +  L P    DS  ++   YR   +  PRL  D W   E +   K G +PHWAK  N      ++ YP F  F   ++++DP  +F   + +++ Y
Sbjct:   27 PTSVEEVREVLALARQQNKRVKVVGG-GHSPSDIAC-------TDGFMIHMGKMNRVLKVDTEKKQVTVEAGILLADLHPQLDKHGLALSNLGAVSDVTAGGVIGSGTHNTGI--KHGILATQVVALTLLTAN------GTILECSESSNAEVFQAARVHLGCLGVILTVTLQCVPQFHLQETTFPSTLKEVLDNL-DSHLKKSEYFRFLWFPHSENVSVIYQDHTNKPPSSSANWFWDYAIGFYL-----------LEFLLWISTFLPG--LVGWINRFFFWLLFNGKKENCNL--SHKIFTYE--------CRFKQHV----------------QDWAI-PREKTKEALLELKAMLEANPK----VVAHYPVEVRFTRGDDILLSPCFQRDSCYMNIIMYRPYGKDVPRL--DYWLAYETI-MKKVGGRPHWAKAHNCTRKDFEKMYPAFQRFCAIREKLDPTGMFLNAYLEKVFY 440          

Query:   40 YGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFK-RSITFNFTDDTDIENVYIEHAKKYEFADITWYASRH--TAVYRYDFRVPLNASGDGVYDF-IGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGP--SEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEILY 526
            +  W     C       PT+  ++R  +A   Q N K K+V    H+   ++C          F I   K +  +Q+D +   VTV++G+ L +L  Q++K+G +L N+     VT+GGV+ SG H +    K G    QV+ +T++    K++G         +  +F AA+V LG LG I  V L    +F     +F  T    ++N+   H KK E+    W+      + +Y+       +++ +  +D+ IGF     L+  S                  L       F  L  N  K +  +   + +  Y+        C +   V                +  AI P  K  + + ++K + + +PK    +  +  + +R+ +  +  L P    DS  ++   YR   +  PRL  D W   E +   K+G +PHWAK  N      ++ YP F+ F D ++++DP  +F   + +++ Y
Sbjct:   10 FQNWAKTYGCSPEMYYQPTSVGEVREVLALARQQNKKVKVVGG-GHSPSDIAC-------TDGFMIHMGKMNRVLQVDKEKKQVTVEAGILLTDLHPQLDKHGLALSNLGAVSDVTVGGVIGSGTHNTGI--KHGILATQVVALTLM----KADGTVLECSESSNADVFQAARVHLGCLGVILTVTLQCVPQFHLLETSFPSTLKEVLDNL-DSHLKKSEYFRFLWFPHSENVSIIYQDHTNKEPSSASNWFWDYAIGFYLLEFLLWTSTYLPR-------------LVGWINRFFFWLLFNCKKESSNL--SHKIFSYE--------CRFKQHV----------------QDWAI-PREKTKEALLELKAMLEAHPK----VVAHYPVEVRFTRGDDILLSPCFQRDSCYMNIIMYRPYGKDVPRL--DYWLAYETI-MKKFGGRPHWAKAHNCTRKDFEKMYPAFHKFCDIREKLDPTGMFLNSYLEKVFY 440          

Query:   18 IHSLTPQSPIQCNQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHH--PLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSS--RVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKY-PKFNAFIDAKKQMDPQNVFSGDWSDEILYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLSTSV 577
            + S+ PQ PI+C+QT CT+ N+YGTW DRKTC+A NVTYPTTE+ LR AVA+  ++NLK K VTKFSHTIP L+CP    + + A  IST KY+S I+I+ + L VT DSGV L ELI++VE  GFS+   PYWEGV+IGG++S+G+HGSSW G+GG+ H+ V+ I++VVP ++SEG+AK++RL+E     L NA KVSLGVLG ISKVKLSIE  FKRS+T+NFT D  +E++++EH KKYEF DITWY SR TAVYRYD R P+N SG+GV DF+GFQ+N ILI + VR  EK  E++ N  GKC TA TTLA+KKL  NGLKN+G IFTGYPVIG QGK+QTSGSCLYSS  R+D +CAWDPR  GLFFYE+TAIFP S+F DF+ DVKKLRD+ P+  CGID YNGI IR+IK S+AYLG +EDS+VIDFNYYRA+D+ TPRLNQDV EE+EQMAF K+GAKPHW KNR + F GV++K  P F+ F++ K ++DP+ +FS +WSDEIL G E  K+DGCALEG C+CSE+RHC+P KGY C  GLVY +ARVCR     V
Sbjct:   22 VQSVPPQPPIRCDQTGCTVSNAYGTWPDRKTCHAANVTYPTTEEDLRKAVAYAAEHNLKVKTVTKFSHTIPKLACP----SGSDALLISTSKYNSVIEIEPELLTVTADSGVSLRELIEKVEGAGFSIGTSPYWEGVSIGGLISTGSHGSSWSGRGGSVHDHVVGISLVVPANQSEGFAKVVRLEEGRDDTLLNAVKVSLGVLGVISKVKLSIEKAFKRSVTYNFTSDVALEDIFMEHGKKYEFGDITWYPSRKTAVYRYDIRAPVNVSGNGVNDFLGFQSNPILISKGVRALEKGFESSKNENGKCTTADTTLAYKKLIGNGLKNSGLIFTGYPVIGRQGKIQTSGSCLYSSSIRIDVACAWDPRYNGLFFYETTAIFPVSRFRDFLLDVKKLRDMKPERLCGIDIYNGIFIRFIKGSKAYLGQTEDSVVIDFNYYRADDELTPRLNQDVMEEMEQMAFVKHGAKPHWGKNRKVGFFGVKQKIGPNFDKFLEVKNKLDPKKMFSSEWSDEILLGTEASKYDGCALEGNCVCSEERHCNPSKGYFCKEGLVYTQARVCRFSPAQV 582          

Query:   13 CIVPLIHSLT---PQSPIQC--NQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPL--FNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCL--YSSRVDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEIL--YGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
            C+  L+H++    P+ P++C    T C + NS G + DR TC A NV YPTTE +L   VA   +   K ++ T++SH+IP L+C    T  N   FIST+  +  +Q DA  + +TV+SGV L +LI +  K G +L   PYW GVT+GG++ +GAHGSS WGKG A H+ V EI +V PGS ++G+AKI  L E      FNAAKVSLGVLG IS+V   ++  FKRS+ +   +D D  +  +   KK+EFAD  W  S+   VYR D RV +N  G+G+YDF  F++    +  + R +E+  E   ++ GKC+TA+T  +    T+ GL NNG  FTGYPVIG Q +M +SGSCL     ++ ++CAWD R+KG+F++++T   P ++   FI D+K L  I+ K+ CG++ Y GIL+RY+ +S AYLG   ++I  D  YYRAND  TPRL +D  EE+EQ+A  KY A PHW KNRNLAF GV +KY    AF+  K+  DP  +FS +W+D+IL   G   +  DGCALEG+CICS+D HC+P KGYLC  G VYKEARVC
Sbjct:   21 CLFTLVHTVISTPPEDPVKCVSGNTNCIVTNSLGAFPDRSTCRAANVAYPTTEAELVSIVAAATKAGRKMRVTTRYSHSIPKLTC----TDGNDGLFISTKFLNHTVQADAKAMTLTVESGVTLRQLIAEAAKVGLALPYAPYWWGVTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRMVSPGSVNDGFAKIRVLSETTTPNEFNAAKVSLGVLGVISQVTFELQPMFKRSLKYVMRNDLDFNDEALTFGKKHEFADFVWLPSQGKVVYRMDDRVAVNTLGNGLYDFFPFRSQLSAVLATTRSSEETQETLRDAHGKCVTATTISSTLFSTSYGLTNNGITFTGYPVIGSQNRMMSSGSCLDGLEDKLTSACAWDSRVKGVFYHQTTFSIPLTQVKSFINDIKSLLKIDSKSLCGLELYYGILMRYVTSSPAYLGKETEAIDFDITYYRANDPLTPRLYEDFIEEIEQIALLKYNALPHWGKNRNLAFDGVIKKYKNAPAFLKVKESYDPNGLFSSEWTDQILGIKGNPTIVKDGCALEGLCICSDDAHCAPSKGYLCRPGKVYKEARVC 585          

Query:    8 IWWVLCIVPLIHSLTPQSPIQC--NQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDEHHPL--FNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEIL--YGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
            ++++  ++    S  P  P++C    T CT+ NSYG + DR TC A NV YP TE +L   VA   Q   K ++ T++SH+I  L C    T      FIST+  +  +Q DA  + +TV+SG+ L +LI +  K G +L   PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PGS +EG+AKI  L E      FNAAKVSLGVLG IS+V   ++  FKRS+T+   +D+D E+  +   KK+EFAD  W  S+   VYR D RV +N SG+G++DF+ F++        +R +E+  E   ++ GKC+ A+   +     + GL NNG IFTGYPV+G Q +M +SGSCL S +  + T+CAWD RIKG FF+++T   P ++   FI D+K L  I  K+ CG++ + GIL+RY+ +S AYLG   +++  D  YYRA D  TPRL +D  EE+EQ+A FKY A PHW KNRNLAF GV  KY    AF+  K   DP+ +FS +W+D+IL   G   +  DGCALEG+CICS+D HC+P KGYLC  G VYKEARVC
Sbjct:   15 LYYIFTLMHTAVSTPPDDPVKCVSGNTNCTVTNSYGAFPDRSTCRAANVAYPKTEAELVSVVAAATQAGRKMRVTTRYSHSITKLVC----TDGTEGLFISTKFLNHTVQADATAMTMTVESGMTLRQLIVEAAKVGLALPYAPYWWGLTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRMVSPGSVNEGFAKIRILSETTTPNEFNAAKVSLGVLGVISQVTFELQPMFKRSLTYTMRNDSDFEDQAVTFGKKHEFADFIWLPSQGKVVYRRDDRVAVNTSGNGLFDFLPFRSQLSAAIAIIRTSEETQERFRDANGKCVGATIISSTLFAPSYGLTNNGIIFTGYPVVGSQNRMMSSGSCLDSLQDGLITACAWDSRIKGEFFHQTTLSVPLTQVKSFISDIKSLVKIEQKSLCGLELHYGILMRYVTSSPAYLGKETEALDFDITYYRAKDPLTPRLYEDFIEEIEQIALFKYNALPHWGKNRNLAFDGVIRKYNNAPAFLKVKDSYDPKGLFSSEWTDQILGIKGNASIVKDGCALEGLCICSKDAHCAPAKGYLCRPGKVYKEARVC 581          

Query:    8 IWWVLCIVPLIH---SLTPQSPIQC--NQTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKI--LRLDEHHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRANDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEIL--YGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
            I+ V CI  L+    S  P+ P++C    T CT+ NSYG + DR TC A NV YPTTE +L   VA   +   K ++ T++SH+I  L+C    T       IST+  +  ++ DA  + +TV+SGV L +LI +  K G +L   PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PGS ++G+AK+  LR       FNAAKVSLGVLG IS+V L ++  FKRS+ +   +D+D  +  +    K+EFAD  W  S+   VYR D RV +N SG+G+ DF+ F++        +R +E+  E   ++ GKC  A+   +    T+ GL NNG IFTGYPVIG Q +M +SGSCL S    + T+C WD RIK  FF+++T   P ++   FI D+K L  I  K+ C ++ Y+GIL+RY+ +S AYLG   +++  D  YYRA D  +PRL +D  EE+EQ+A FKY A PHW KNRNLAF GV +KY    AF+  K+  DP  +FS +W+D+IL   G   +  DGCALEG+C+CSED HC+P KGY C  G VYKEARVC
Sbjct:   20 IFVVHCISTLVFTTISTPPEDPVKCVSGNTNCTVTNSYGAFPDRSTCRAANVAYPTTEAELISVVAAATKAGRKMRVTTRYSHSITKLAC----TDGTDGLLISTKFLNHTVRTDATAMTLTVESGVTLRQLIAEAAKVGLALPYAPYWWGLTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRIVSPGSVNDGFAKVRVLRETTTPKEFNAAKVSLGVLGVISQVTLKLQPMFKRSLRYVMRNDSDFGDQAVTFGMKHEFADFIWLPSQGKVVYRMDDRVAVNTSGNGLLDFMPFRSQLSAALAIIRSSEETQERFRDANGKCAGATLITSTLFATSYGLTNNGMIFTGYPVIGSQNRMMSSGSCLDSLHDGLITACPWDSRIKSEFFHQTTFSIPLTQVKSFINDIKSLVKIESKSLCVLELYDGILMRYVTSSPAYLGKETEALDFDLTYYRAKDPLSPRLYEDFIEEIEQIALFKYNALPHWGKNRNLAFDGVIKKYKNVPAFLKVKESYDPMGLFSSEWTDQILGIKGNVTIIKDGCALEGLCVCSEDAHCAPTKGYFCRPGKVYKEARVC 589          

Query:    5 TYFIWWVLCIVPLIHSLTPQSPIQCN--QTICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDE--HHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSRVD---TSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRA-NDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEI--LYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLST 575
            ++++  + C      S  P  P+ C    T+CT+ NSYG + DR  C A  V YP TE +L   VA   +   K ++VT++SH+ P L C    T       IST+  +  +  + +   +TV+SGV L +LI++  K   +L   PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PG  S+GY K+  L E      F AAKVSLGVLG IS+V   ++  FKRS+ +   +D+D  +  +   +++EFAD  W  S+   VYR D RVPLN SGDG+++F  F++   L+    R  E+  E+  ++  KC+ A    +   L + G+ NNG IFTGYPVIG Q  M +SGSCL  SR D   T+C WDPRIKG FF+++T     +    FI D+K L  I PK+ C ++  NGILIRY+ +S A+LG  E ++  D  YYR+ ND   PRL +D  EE+EQMA FKY A PHW KNRNLAF G   KY   NAF+  K++ D   +FS +W+D+I  L G   +   GCALEG+CICSED HC+P KGYLC  G VY+EARVC  +S+
Sbjct:    2 SFWLSLIFCFFTFASSSPPDDPVNCEFGNTMCTVTNSYGAFPDRSICKAAKVEYPRTEAELVSIVAAATRAGQKMRVVTRYSHSFPKLVC----TDGKDGTLISTKFLNHVVTTNPEAKTLTVESGVTLRQLIEEAAKFDLALPYAPYWWGLTVGGMMGTGAHGSSLWGKGSAVHDYVTEIRLVSPGLASDGYVKVQVLSETIDPEEFRAAKVSLGVLGVISQVTFELQPMFKRSLNYVMRNDSDFGDQAVSFGERHEFADFLWLPSQGKVVYRMDGRVPLNTSGDGLFEFFPFRSQLSLVLAIDRSLEESEESLEDANMKCVRAKLVSSSMFLMSYGVTNNGLIFTGYPVIGMQNHMMSSGSCL-DSRQDGLITACPWDPRIKGQFFHQTTFSVSLTNVKSFINDIKALVKIEPKSLCVLEGSNGILIRYVTSSLAFLGKEEKALDFDLTYYRSKNDPLAPRLYEDYIEEIEQMAIFKYNALPHWGKNRNLAFDGAIRKYKNANAFLKVKEKFDSLGLFSTEWTDQILGLKGNVTIVKQGCALEGLCICSEDSHCAPTKGYLCRPGKVYREARVCTRVSS 577          

Query:   12 LCIVPLIHSLTPQSPIQCNQ--TICTLENSYGTWNDRKTCYALNVTYPTTEQQLRLAVAHVVQNNLKAKIVTKFSHTIPSLSCPKQNTTNNHAFFISTEKYDSGIQIDADNLAVTVDSGVRLGELIDQVEKNGFSLVNVPYWEGVTIGGVVSSGAHGSSWWGKGGAFHEQVLEITVVVPGSKSEGYAKILRLDE--HHPLFNAAKVSLGVLGAISKVKLSIEHRFKRSITFNFTDDTDIENVYIEHAKKYEFADITWYASRHTAVYRYDFRVPLNASGDGVYDFIGFQANSILIPESVRGAEKLLENTGNSKGKCLTASTTLAFKKLTANGLKNNGQIFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRA-NDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEI--LYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVC 570
             C      S  P  P++C     +CT+ NSYG + DR  C A  V YP TE +L   VA   +   K ++VT++ H+IP L C    T       IST+  ++ +  + +   +TV+SGV L +LI +  +   +L + PYW G+T+GG++ +GAHGSS WGKG A H+ V EI +V PG  S+GY K+  L E      F AAKVSLGVLG IS+V   ++  FKRS+TF   +D+D  +  +   +K+EFAD  W  S+   VYR D RVP+N SG+G++DF  F+    +    +R  E+  E++G++  KC  A    +F    + G+ NNG  FTGYPVIG Q  M +SG+CL S +  + TSC WDPRIKG FF+++    P ++   FI D+K L  I PK+ C ++  NGILIRY+ +S A+LG  E ++  D  YYR+ +D   PRL +D  EE+EQMA FKY A PHW KNRNLAF GV  KY   N F+  K++ DP  +FS +W+++I  L G   +  +GCALEG+C+CS+D HC+P+KGYLC  G VY +ARVC
Sbjct:   10 FCFCTFASSTPPDDPVKCESGNNMCTVTNSYGAFPDRSICEAAKVEYPKTEAELVSIVAAATRAGQKVRVVTRYVHSIPKLVC----TDGKDGVLISTKFLNNVVGTNPEAKTLTVESGVTLRQLIGEAAELELALPHAPYWWGLTVGGLMGTGAHGSSLWGKGSAVHDYVSEIRMVSPGLASDGYVKVRVLSETIDPDEFRAAKVSLGVLGVISQVTFQLQPMFKRSLTFVMQNDSDFGDQAVTFGEKHEFADFLWLPSQGKVVYRMDDRVPVNTSGNGLFDFFPFRPQLSVALAIIRSLEESEESSGDANDKCARAEQITSFLFSISYGVTNNGMEFTGYPVIGKQNHMMSSGTCLDSHQDGLITSCPWDPRIKGQFFHQTAFSIPLTRVKGFINDIKALVKIEPKSLCALERSNGILIRYVTSSPAFLGKEEKALDFDLTYYRSKDDPLAPRLYEDFIEEIEQMAIFKYNALPHWGKNRNLAFDGVIRKYKNANTFLKVKERFDPLGLFSTEWTNQILGLKGNVTIVKEGCALEGLCVCSDDAHCAPKKGYLCRPGKVYTKARVC 573          

Query:  345 IFTGYPVIGYQGKMQTSGSCLYSSR--VDTSCAWDPRIKGLFFYESTAIFPASKFGDFIKDVKKLRDINPKNFCGIDNYNGILIRYIKASEAYLGPSEDSIVIDFNYYRA-NDQFTPRLNQDVWEELEQMAFFKYGAKPHWAKNRNLAFLGVQEKYPKFNAFIDAKKQMDPQNVFSGDWSDEI--LYGKELVKFDGCALEGMCICSEDRHCSPQKGYLCTHGLVYKEARVCRLLS 574
            IFTGYPVIG Q ++ +SG+CL S +  + TSC WDPRIKG FFY++    P +   DFI D+K L  I PK+ CG++   G+L+RY+ +S AYL   E ++  D  YYR+ +D +TPRL +D  EE+EQMA  KY A PHW KNRNLAF G  +KY   N F+  K+++DP  +FS +W+D+I  L G   +   GCA EG+CICS+D HC+P KGY+C  G VYKEARVC L++
Sbjct:   17 IFTGYPVIGSQDRIMSSGACLDSHQNGLITSCPWDPRIKGEFFYQTALSVPLTHVKDFINDIKALVKIEPKSLCGLELNYGVLVRYVTSSPAYLRKEEKALDFDLTYYRSKDDPWTPRLYEDYMEEIEQMAILKYNALPHWGKNRNLAFDGAIKKYKNANTFLKVKERLDPWGLFSTEWTDQILGLKGNVTIVKQGCAPEGLCICSDDSHCAPNKGYMCRPGKVYKEARVCTLVT 251