Ca_04403, Ca_04403_v1.0_kabuli (mRNA) Cicer arietinum

Query:   55 PSLSFLTS---QNLTLFGDASFTDNSITLTKQLTCLSS---------SSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASN-GQGSSFHLVHHWKFKTL-SYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSS-----IVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSS--STRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLSADEAPYLTPRSQF 2034
            P+LS   S   QNLTL+GDA F D +I+LT+Q  C  S         SS  GRA Y+YP++FL+P TN+T                     GDG AFLI+S    S +  NG++GLP+    + S+ AVEFDT FDP  GDIN NH+GID+S++ S +SVDA+S+G DLKSGK + AWIEY D +K++RVWVGYS  +P +P+L++ +DLS + KE+MHVGFSASN G GS+ H+V  WKF+T  S+S ++   +  ++ +C +C                        L I                  +      G  ++I E         ++P RLSL+EI SAT GFN++ +VG+GASA VY+GS+P  G VAVKRF++     C  NPF TEF TM G LRHKNLVQ +GWC EG E  LV+EYLPNGSL + LH+  +S      IVLSWKQRVNIILGVA+ALTYLHEECERQIIHRDVKTCN+MLDA+FNAKLGDFGLAE+YEHS+  + R AT+PAGTMGYLAPEYVY+GVP+ KTDVYSFGVVV+EV TGR+PVG+DG V+ D +W+ WE  ++++ AD  L  +FD  EMER+L+VG+VC HPD EKRPRV+DA R+I+ EAPLP+LP  +P +RIRP       E + ++ D L  ++ P++TP+S F
Sbjct:   22 PTLSHRFSPPLQNLTLYGDAFFRDRTISLTQQQPCFPSVTTPPSKPSSSGIGRALYVYPIKFLEPSTNTTASFSCRFSFSIIASPSCPF--GDGFAFLITSNAD-SFVFSNGFLGLPNP---DDSFIAVEFDTRFDPVHGDINDNHVGIDVSSIFSVSSVDAISKGFDLKSGKKMMAWIEYSDVLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGIGSALHIVERWKFRTFGSHSDAIQEEEEEKDEECLVCSGEVSENPKEIHRKGFNFRVTVVGLKIPVWSLLPGLAAIVILVAFIVFSLICG-KKRISEEADSNSGLVRMPGRLSLAEIKSATSGFNENAIVGQGASATVYRGSIPSIGSVAVKRFDREHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSALLAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPVGDDGAVLVDLMWSHWETGKVLDGADIMLREEFDAEEMERVLMVGMVCAHPDSEKRPRVKDAVRIIRGEAPLPVLPARRPLLRIRP-----ANEAEEMIVDGLVGEDLPWMTPKSHF 690          

Query:   73 TSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYF-AVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDAL-SRGVDLKSGKIITAWIEYRDDMKMVRVWVGYS-----STRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYS---------HSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRK----IKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDV-AVKRFEKVDDLDCLHNPFA--TEFA---TMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHR-NLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGED----GTV-VGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKP 1923
            T +NLT  GD+   +  + LT++L    +SS  G   Y  P+RF DP +N+T                     GDG+AF +S        S  GY+GL + +Q   + F A+EFDT  DP   D NGNHIG+D+ ++ S ++ D L S  +DLKSGK IT+WI+Y++D++++ V++ Y+     + +P  P+L+  +DLS      M+VGFS S    +  HL+ +W FKT  +          H+VS   ++ +    +                        A+G+G               IC+ L     F  K    +K  +  + +        S  E+ +AT GF+   ++G GA   VY+      G + AVKR          HN     TEF    +++ CLRHKNLVQL+GWC E  EL+LVYE++PNGSLDK+L++ + T ++ L W  R+NI +G+A+AL+YLH ECE+Q++HRD+KT N+MLD +FNA+LGDFGLA + EH  S   +T+ AGTMGYLAPEY+  G  T KTD +S+GVV++EVA GR+P+ ++     TV + D+VW L  + R++EA D +L G+FD   M+++LLVGL C HPD  +RP +R   +++  E     +P+ KP
Sbjct:   39 TIRNLTFLGDSHLRNGVVGLTRELGVPDTSS--GTVIYNNPIRFYDPDSNTTASFSTHFSFTVQNLNPDPTSAGDGLAFFLSHDNDTLG-SPGGYLGLVNSSQPMKNRFVAIEFDTKLDPHFNDPNGNHIGLDVDSLNSISTSDPLLSSQIDLKSGKSITSWIDYKNDLRLLNVFLSYTDPVTTTKKPEKPLLSVNIDLSPFLNGEMYVGFSGSTEGSTEIHLIENWSFKTSGFLPVRSKSNHLHNVSDSSVVNDDPVVI-------------PSKKRRHRHNLAIGLG---------ISCPVLICLALFVFGYFTLKKWKSVKAEKELKTELITGLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVSSGTISAVKRSR--------HNSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTEHDKSP-VSTLTAGTMGYLAPEYLQYGTATEKTDAFSYGVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVLEAVDERLKGEFDEEMMKKLLLVGLKCAHPDSNERPSMRRVLQILNNEIEPSPVPKMKP 653          

Query:   61 LSFLTSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEE-------GDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDV-AVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPV----GEDGTVVG------DYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKP 1923
            L  LT  +L L GDA   + +I LT++L+  +S++  G+A Y  PV+F  P T S                      G G+AF+IS    +   S  G++GL  +    S + AVEFDT  D    D+NGNH+G+DL+ VVS A  D  +  +DLKSG  + +WI Y    +++ V+V YS+ +P +PIL+  +DL     + M VGFS S    +  H V  W F +     S SP  M                                          + G              + +++  KK  ++  ++ +S   +  K P   +  E+  AT  F+   ++G GA   VYKG L   G++ A+KR   +   +     F +E + ++G LRH+NL++L+G+C E  E++L+Y+ +PNGSLDK L+ + T+   L W  R  I+LGVA+AL YLH+ECE QIIHRDVKT N+MLDA+FN KLGDFGLA   EH  S  DAT  AGTMGYLAPEY+ +G  T KTDV+S+G VV+EV TGR+P+     E G   G      D+VW L+ + +++ A D +L  +F+  EM R+++VGL C  PD   RP +R   +++  EA +P +P +KP
Sbjct:   39 LGTLTLSSLKLLGDAHLNNGTIKLTRELSVPTSTA--GKALYGKPVKFRHPETKSPASFTTYFSFSVTNLNPSSI--GGGLAFVISPDEDYLG-STGGFLGLTEETGSGSGFVAVEFDTLMDVQFKDVNGNHVGLDLNAVVSAAVADLGNVDIDLKSGNAVNSWITYDGSGRVLTVYVSYSNLKPKSPILSVPLDLDRYVSDSMFVGFSGSTQGSTEIHSVDWWSFSSSFEESSESPPPMPNSPPPSSPSSSITPSLSTVRRKTADPSSSCRNKLCKKSPAAVAGVVTAGAFFLALFAGVIIWVYSKK--IKYTRKSESLASEIMKSPREFTYKELKLATDCFSSSRVIGNGAFGTVYKGILQDSGEIIAIKRCSHISQGN---TEFLSELS-LIGTLRHRNLLRLQGYCREKGEILLIYDLMPNGSLDKALYESPTT---LPWPHRRKILLGVASALAYLHQECENQIIHRDVKTSNIMLDANFNPKLGDFGLARQTEHDKSP-DATAAAGTMGYLAPEYLLTGRATEKTDVFSYGAVVLEVCTGRRPITRPEPEPGLRPGLRSSLVDWVWGLYREGKLLTAVDERL-SEFNPEEMSRVMMVGLACSQPDPVTRPTMRSVVQILVGEADVPEVPIAKP 661          

Query:   76 SQNLTLFGDASFTDN-SITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEE--SSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDA-------LSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIK-EGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGD--VAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVG----EDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLP 1902
            S NLTL G A      +I LT +     +    G AFY  P+RF     N                       G G+AF I+ T        + Y+GL + ++    S +FAVEFDT  D    DIN NH+GID++++ S  S  A         + + L  G++I AWI+Y  + K + V +   S +P   +L+  VDLS    + M+VGFSAS G  +S H +  W F     + S+S   +                                 LG+                  V +      VRK+K E +   ++ +  P R S  E+  AT GF    L+G G   KVYKG LP G D  VAVKR             F +E ++ +G LRH+NLVQL GWC   ++L+LVY+++PNGSLD  L       ++L+WKQR  II GVA+ L YLHE  E+ +IHRD+K  NV+LD++ N ++GDFGLA++YEH S    AT   GT GYLAPE   SG  T  TDVY+FG V++EVA GR+P+      +  V+ D+VW+ W+   I +  DR+L G+FD  E+  ++ +GL+C +   E RP +R     ++K+ P P
Sbjct:   35 SPNLTLNGVAEIAPTGAIRLTTE-----TQRVIGHAFYSLPIRFKPIGVNRA--LSFSTSFAIAMVPEFVTLGGHGLAFAITPTPDLRGSLPSQYLGLLNSSRVNFSSHFFAVEFDTVRDLEFEDINDNHVGIDINSMESSISTPAGYFLANSTKKELFLDGGRVIQAWIDYDSNKKRLDVKLSPFSEKPKLSLLSYDVDLSSVLGDEMYVGFSASTGLLASSHYILGWNFNMSGEAFSLSLPSL---------------PRIPSSIKKRKKKRQSLILGVS--------LLCSLLIFAVLVAASLFVVRKVKDEDRVEEWELDFGPHRFSYRELKKATNGFGDKELLGSGGFGKVYKGKLP-GSDEFVAVKRISHESRQGV--REFMSEVSS-IGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGSLDMYLFDE-NPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDP-GATRVVGTFGYLAPELTKSGKLTTSTDVYAFGAVLLEVACGRRPIETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNGEFDEEEVVMVIKLGLLCSNNSPEVRPTMRQVVMYLEKQFPSP 624          

Query:   64 SFLTSQNLTLFGDASFTD--NSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLI---SSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRG---------VDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRF-----EKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNE-LVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLM--GKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKK 1887
            S  T+ N  L G+A+     + +TLT Q T      S GR   LYP R ++  ++S                      G G AF+    S T+  SS    G     ++    S  FAVEFD   +    DIN NH+G+D++++ S AS  A   G         + L SG+   AWIE+      V +    SS +P  P+++  ++L+    + M VGF+AS GQ    H +  W F   ++S           GD  +                           I G              +C ++ R++   R+  EG    ++T   P R+   ++  AT GF+ + ++G G ++KVY+G L  G +VAVKR      E V       + F  E +++ G LRHKN+V LKGW  +G E L+L+YEY+ NGS+DK   R    + +L+W++R+ +I  +A+ + YLHE  E +++HRD+K+ NV+LD D NA++GDFGLA++   S      T   GT GY+APE V +G  + +TDVYSFGV V+EV  GR+P+ E    + +++W L EK+++++  D ++   G F V E+E  L +GL+CVHPD   RP++R   +++++
Sbjct:   30 SNFTTTNTLLLGNATVKSPPSILTLTNQTTF-----SIGRG--LYPSR-INASSSSASPLPFATSFIFSMAPFKHLSPGHGFAFVFLPFSETSAASSSQHLGLFNFTNNGDPNSRIFAVEFDVFANQEFNDINDNHVGVDVNSLTSVASETAGFYGGRDGQRFTELKLNSGENYQAWIEFNGSAINVTM-ARASSRKPIRPLISIPLNLTGVLLDDMFVGFTASTGQLVQSHRILSWSFSNSNFSI----------GDALITRNLPSFKLSGDSVLKSKGF-------IAGVSSGVVLLVSVIGLLCFYVVRRR---RQRLEGDVEDWETEYWPHRVQYKDVLEATKGFSDENMIGYGGNSKVYRGVLE-GKEVAVKRIMMSPRESVGAT----SEFLAEVSSL-GRLRHKNIVGLKGWSKKGGESLILIYEYMENGSVDK---RIFDCNEMLNWEERMRVIRDLASGMLYLHEGWETKVLHRDIKSSNVLLDKDMNARVGDFGLAKLQNTSKEMVSTTHVVGTAGYMAPELVKTGRASAQTDVYSFGVFVLEVVCGRRPIEEGREGIVEWIWGLMEKDKVVDGLDERIKANGVFVVEEVEMALRIGLLCVHPDPRVRPKMRQVVQILEQ 621          

Query:   82 NLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRF-SSLSRNGYMGL---PSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDAL--------SRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSST------------RPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVL-HRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDG----TVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLL 1908
            +L L G A+     + LT      ++++  G AFY  P++F     +S                      G G+AF++S T    S+ S N  +G+    +DN+  +  FAVE DT+ +    D  GN +GID++++VS  S DA         +  + L SGK I  WI+Y    K++ V +    T            +P  P+L+  ++LSE F E M+VGFS S G   S   +  W FK    + S   +D+       L                         L +GG                V+L +KK +   +++     ++    P R S   +  AT GF ++ L+G G   KVYKG LP G  +AVKR     D +     +  E A+M G LRHKNLV L G+C    EL+LVY+Y+PNGSLD  L H+N      L+W QRVNII GVA+AL YLHEE E+ ++HRD+K  N++LDAD N KLGDFGLA  ++   +  +AT   GT+GY+APE    GV T  TDVY+FG  ++EV  GR+PV  D      ++  +V +  +++ + +  D KL+  F V E + +L +G++C   + E RP +R   + ++    +P +
Sbjct:   39 DLELDGMANTNHGPLHLTN-----NTNTGTGHAFYNIPIKFT---ASSLSSFSFSTEFVFAIFPLQKSTYGHGMAFVVSPTKDLRSNGSANSNLGIFNRANDNKTATHIFAVELDTNQNSESFDKGGNDVGIDINSIVSVESADASYFNARKGKNISLPLASGKSILVWIDYDGIEKVLNVTLAPVQTPKPDSPYFSSFIKPKVPLLSRSINLSEIFTETMYVGFSGSTGSIKSNQYILGWSFKQGGKAES---LDISR-----LSNPPPSPKRFPLKEVLGATISTIAFLTLGGI---------------VYLYKKKKYAEVLEQ-----WEKEYSPQRYSFRILYKATKGFRENQLLGAGGFGKVYKGILPSGTQIAVKRV--YHDAEQGMKQYVAEIASM-GRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNKLKD--LTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNL-EATRVVGTIGYMAPELTAMGVTTTCTDVYAFGAFILEVVCGRRPVDPDAPREQVILVKWVASCGKRDALTDTVDSKLI-DFKVEEAKLLLKLGMLCSQINPENRPSMRQILQYLEGNVSVPAI 633          

Query:  973 RKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGD-VAVKRFEKVDDLDCLH------NPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTV----VG------DYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKP 1923
            ++++   S   +  K P   S  E+ + T  FN+  ++G GA   VY+G LP  GD VAVKR        C H      N F +E + ++G LRH+NLV+L+GWC E  E++LVY+ +PNGSLDK L     S   L W  R  I+LGVA+AL YLH ECE Q+IHRDVK+ N+MLD  FNAKLGDFGLA   EH  S  +AT+ AGTMGYLAPEY+ +G  + KTDV+S+G VV+EV +GR+P+ +D  V    VG      ++VW L+++ ++  AAD +L GKFD  EM R+L+VGL C HPD   RP +R   +M+  EA +P++P+S+P
Sbjct:  345 KRVERSDSFASEIIKAPKEFSYKELKAGTKNFNESRIIGHGAFGVVYRGILPETGDIVAVKR--------CSHSSQDKKNEFLSELS-IIGSLRHRNLVRLQGWCHEKGEILLVYDLMPNGSLDKALFE---SRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDESFNAKLGDFGLARQIEHDKSP-EATVAAGTMGYLAPEYLLTGRASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQRHNVGVNPNLVEWVWGLYKEGKVSAAADSRLEGKFDEGEMWRVLVVGLACSHPDPAFRPTMRSVVQMLIGEADVPVVPKSRP 665          

Query:   64 SFLTSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKT 744
            S L   NL L GDA  ++  + LT+ L+  +S +  G+  Y  P+RF  P T+                       G G+AF+IS       ++  G +GL   N   S + AVEFDT  D    DIN NH+G D++ VVS  S D  +  +DLKSG  I +WIEY    ++  V V YS+ +P  PIL+  +DL     +FM VGFS S    +  H +  W F +
Sbjct:   27 STLAISNLKLLGDARLSNGIVGLTRDLSVPNSGA--GKVLYSNPIRFRQPGTHFPTSFSSFFSFSITNVNPSSI--GGGLAFVISPDANSIGIA-GGSLGLTGPNGSGSKFVAVEFDTLMDVDFKDINSNHVGFDVNGVVSSVSGDLGTVNIDLKSGNTINSWIEYDGLTRVFNVSVSYSNLKPKVPILSFPLDLDRYVNDFMFVGFSGSTQGSTEIHSIEWWSFSS 248          

Query:   73 TSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRF---SSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDL-------SNVVSFASVDALS-RGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHS-----------VSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGG-DVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCC-EGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLM---GKFDVV-EMERMLLVGLVCVHPDYEKRPRVRDAARMIK 1884
            +S N++LFG A+     +TLT Q     +S + GRA Y   +R  DP+T+S                      G GI FL + +T     SS    G   L ++    +  F VEFD   +    DI+ NH+GID+       SN   + S D +  + + L  G+    WI+YRD +  V + V     RP  P+L++ ++LS+  ++ M VGF+A+ G+    H +  W F   ++S S           V P D I +   F+                         + + G              + +F   +K   R  K      ++    P R+   EI S T GF++  ++G G + KVYKG L  G  +VAVKR  + +  D +   F  E +++ G L+H+NLV L+GWC  E    +LVY+Y+ NGSLD+ +  N      LS ++R+ I+ GVA+ + YLHE  E +++HRD+K  NV+LD D   +L DFGLA V+ H    R   +  GT GYLAPE V +G  + +TDV+++G++V+EV  GR+P+ E    + D+VW L E+  I+   D ++M   G  +V+ E ER+L +GL+C HPD  KRP +R   ++ +
Sbjct:   31 SSSNVSLFGIATIESKILTLTNQ-----TSFATGRALYNRTIRTKDPITSSV--LPFSTSFIFTMAPYKNTLPGHGIVFLFAPSTGINGSSSAQHLGLFNLTNNGNPSNHIFGVEFDVFANQEFSDIDANHVGIDVNSLHSVYSNTSGYWSDDGVVFKPLKLNDGRNYQVWIDYRDFVVNVTMQVA-GKIRPKIPLLSTSLNLSDVVEDEMFVGFTAATGRLVQSHKILAWSFSNSNFSLSNSLITTGLPSFVLPKDSIVKAKWFV---------------FVLVLICFLVVALVG--------------LVLFAVVRKRLERARKRALMEDWEMEYWPHRIPYEEIESGTKGFDEKNVIGIGGNGKVYKGLLQGGVVEVAVKRISQ-ESSDGMRE-FVAEISSL-GRLKHRNLVSLRGWCKKEVGSFMLVYDYMENGSLDRWIFENDEKITTLSCEERIRILKGVASGILYLHEGWESKVLHRDIKASNVLLDRDMIPRLSDFGLARVHGHEQPVRTTRV-VGTAGYLAPEVVKTGRASTQTDVFAYGILVLEVMCGRRPIEEGKKPLMDWVWGLMERGEILNGLDPQMMMTQGVTEVIDEAERVLQLGLLCAHPDPAKRPSMRQVVQVFE 621          

Query:   82 NLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGL---PSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDA-------LSRGVDLKSGKIITAWIEYRDDMKMVRVWVG-YSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLP-LGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPV-----GEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLL 1908
            +L++ G  + T N +      T   +    G AFY  P+RF D    +                      G GIAF+++        + + Y+GL    ++  E +  FAVE DT       D N NH+GID++++ S  S  A         + + L S K +  W++Y      + V +  ++  +P  P++ ++ DLS    + M+VGFS++ G   S H +  W F     +    P+ +                                   IG               +C  +RR++ F  +++E +   F  N    R    ++  AT GF +  L+G G    VYKG +P    ++AVKR             F  E  + +G + H+NLV L G+C    EL+LVY+Y+PNGSLDK L+   T  + L+WKQR+ +ILGVA+ L YLHEE E+ +IHRDVK  NV+LD + N +LGDFGLA +Y+H S  +  T   GT+GYLAPE+  +G  T+ TDV++FG  ++EVA GR+P+      ++  ++ D+V+ LW K  I+ A D  +  + D  E+E +L +GL+C H D   RP +R     ++ +A LP L
Sbjct:   38 DLSIQGITTVTPNGLLKLTNTTVQKT----GHAFYTKPIRFKDSPNGTVSSFSTSFVFAIHSQIAILS--GHGIAFVVAPNASLPYGNPSQYIGLFNLANNGNETNHVFAVELDTILSTEFNDTNDNHVGIDINSLKSVQSSPAGYWDEKGQFKNLTLISRKPMQVWVDYDGRTNKIDVTMAPFNEDKPTRPLVTAVRDLSSVLLQDMYVGFSSATGSVLSEHYILGWSF---GLNEKAPPLALSR----------------LPKLPRFEPKRISEFYKIGMPLISLFLIFSFIFLVCYIVRRRRKFAEELEEWEK-EFGKN----RFRFKDLYYATKGFKEKGLLGTGGFGSVYKGVMPGTKLEIAVKRVSHESRQGM--KEFVAEIVS-IGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYN--TPEVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQ-TTHVVGTLGYLAPEHTRTGRATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLRGDAKLPEL 627          

Query:  292 GDGIAFLISSTTRFSSLSRNGYMGL---PSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSR-------GVDLKSGKIITAWIEYRDDMKMVRVWVG-YSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGG-DVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPV-----GEDGTVVGDYVWNLWEKNRIIEAADRKL-MGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLL 1908
            G GIAF+++ T        + Y+GL    ++  + +  FAVEFDT      GD N NH+GIDL+ + S     A  R        + L S K I  WI+Y +    + V V  + S +P  P+++ + DLS    E M+VGFS++ G   S H +  W F+     +  +PM  + +                                IG                   +RRKK +  ++ + ++  F  N    R    E+  AT GF +  L+G G   +VY+G LP    +VAVKR     D       F  E  + +G + H+NLV L G+C    EL+LVY+Y+PNGSLDK L+ N  ++  L WKQR  II GVA+ L YLHEE E+ +IHRDVK  NV+LDADFN +LGDFGLA +Y+H S  +  T   GT+GYLAPE+  +G  T  TDVY+FG  ++EV +GR+P+      +D  ++ ++V++LW +  I+EA D KL    +D+ E+E +L +GL+C H D   RP +R   + ++ +  LP L
Sbjct:  102 GHGIAFVVAPTLGLPFALPSQYIGLFNISNNGNDTNHIFAVEFDTIQSSEFGDPNDNHVGIDLNGLRSANYSTAGYRDDHDKFQNLSLISRKRIQVWIDYDNRSHRIDVTVAPFDSDKPRKPLVSYVRDLSSILLEDMYVGFSSATGSVLSEHFLVGWSFRL----NGEAPMLSLSK---------------LPKLPRFEPRRISEFYKIGMPLISLSLIFSIIFLAFYIVRRKKKYEEELDDWET-EFGKN----RFRFKELYHATKGFKEKDLLGSGGFGRVYRGILPTTKLEVAVKRVSH--DSKQGMKEFVAEIVS-IGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPETT--LDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQ-TTHVVGTLGYLAPEHSRTGRATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLRGDMALPEL 628          

Query:   55 PSLSFLTSQNLTLFGDASFTDNSITLTKQL-TCLSSSSS----FGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXX-ICVFLRRKKG-FVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLSADEAPYLTPRSQFY 2037
            PSLS L SQN+TLFGDAS+TD SITLTKQ  TCLSSSSS     GRAFYLYPVRFLDPLTNST                      DGIAFLISSTT FSSLS NGYMGLP  +Q+  SYFAVEFDTSFDPSLGDINGNH+GIDL +VVSFAS D LSR +DLKSGKII AWIEYRDDMKMVRVWV YSSTRPPTPI+AS +DLSERFKEFMHVGFSASNG+GSS HLVHHW+FKTLSYSHSV PMD +EEGDCFLCY                      ALGIGG               ICV ++RK+G  +RKI+EGQS RFQTNKVP++LSLSEITSATMGFN+D LVGEGASAKVYKGSLP GGDVAVKRFEK+D+LD LHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNL+SS VLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCN+MLD DFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVV+IEVATGRKPV +DGTV+GDYVW+LWEKNR++EAAD KLMG+FDV+EMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLP +KP VRI PVCPNDTPETQ+VVGDW+S DEAPYLTPRSQFY
Sbjct:   20 PSLS-LPSQNITLFGDASYTDTSITLTKQQHTCLSSSSSSSSGIGRAFYLYPVRFLDPLTNSTASFSCRFSFSILSSPSCPSS-SDGIAFLISSTTDFSSLS-NGYMGLPHSDQD--SYFAVEFDTSFDPSLGDINGNHVGIDLGSVVSFASADLLSRRIDLKSGKIINAWIEYRDDMKMVRVWVSYSSTRPPTPIIASFIDLSERFKEFMHVGFSASNGKGSSIHLVHHWQFKTLSYSHSVGPMDNVEEGDCFLCYAGDSKI----------------ALGIGGITAFVVGSALALIVVICVLIKRKRGGVIRKIREGQSSRFQTNKVPVKLSLSEITSATMGFNRDRLVGEGASAKVYKGSLPFGGDVAVKRFEKIDELDRLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLSSSFVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNIMLDVDFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVIIEVATGRKPVADDGTVIGDYVWSLWEKNRLVEAADPKLMGEFDVIEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPTTKPWVRIMPVCPNDTPETQDVVGDWVSNDEAPYLTPRSQFY 666          

Query:   58 SLSFLTSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVS-FASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXX------ALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKI---KEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCP-NDTPETQNVVGDWLSADEAPYLTPRSQFY 2037
            +L F  S NLTL+GDA FT N+ITLT Q +   SSSS GRAF++YPVRFLDP TNST                      DG+AFLI+S+T F +LS +GYMGLPS +   SS+FAVEFDT+F P LGDIN NH+ +D++++ S FASVDA SRGVDLKSGKIITAW+EYR  M+MVRVW+GYSSTRPPTPILA+ +DLSER ++FMHVGF+ASNG+GSS HLVHHW+FKT  Y      MD++EEGDCFLCY                            ALG+ G              +CVFL + K  +RK    ++GQSCRFQT+KVP RLSLS+I SATMGFN+D LVGEGASAKVYKG LP GGDVAVKRFE+ + LDCLHNPFATEFATMVG LRHKNLVQLKGWCCEGNELVLVYE+LPNGSL+KVLHRN  SSIVLSW+QR+NI+LGVA+ALTYLHEECERQIIHRDVKTCN+MLDADF AKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVV+EVATGRKPV +DGTVV D+VW LW K ++IEAAD +LMGKFD  EMERMLLVGL+CVHPDYEKRPRVR+A R++KKEAPLPLLP SKPRVRIRP+CP +DT E Q+VV DWLS D+APYLTPRSQFY
Sbjct:   21 TLPFFPSDNLTLYGDAFFTRNAITLTTQHS-KCSSSSIGRAFFIYPVRFLDPQTNSTASFSCRFSFSILSSPSCPS--ADGLAFLIASSTHFPTLS-SGYMGLPSSSF--SSFFAVEFDTAFHPFLGDINDNHVAVDVNSLASSFASVDAASRGVDLKSGKIITAWVEYRHAMRMVRVWIGYSSTRPPTPILATQIDLSERLEDFMHVGFTASNGEGSSVHLVHHWQFKTFGYDDDSRSMDVVEEGDCFLCYEGDSTGKREGSSMSNKDDIERRKKIGEMALGLAGLTAFVVSGLAAMVVVCVFLTKNKACIRKKNKEEQGQSCRFQTSKVPTRLSLSDIKSATMGFNRDRLVGEGASAKVYKGYLPFGGDVAVKRFERDNGLDCLHNPFATEFATMVGYLRHKNLVQLKGWCCEGNELVLVYEFLPNGSLNKVLHRNFNSSIVLSWQQRLNIVLGVASALTYLHEECERQIIHRDVKTCNIMLDADFTAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVLEVATGRKPVEDDGTVVVDFVWGLWGKRKLIEAADPRLMGKFDEKEMERMLLVGLLCVHPDYEKRPRVREATRILKKEAPLPLLPTSKPRVRIRPICPDDDTSEAQSVVADWLSTDDAPYLTPRSQFY 685          

Query:   76 SQNLTLFGDASFTDNSITLTKQLT-CLSSSSS------FGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQ-EESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXX---ALGIGGXXXXXXXXXXXXXXICVF-LRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVG--DWLSADEAPYLTPRSQF 2034
            + N+TL GDA   +N+I+LT  LT C SSSSS       GRAFY YP+RFLD  TN+T                     GDGIAF+I+      S SR GYMGLP      + S+FAVEFDT FDP +GDINGNHIGID++ VVS ASVD +S+G+DL SG+ ITAWIEYRD +KM+RVWVGYSSTRPPTP+L + +DLS++FKEFM VGFSASNGQGSS H+V  WKFKT        PM+ +EEGDCF+C                          ALG+GG              IC   ++R+K   R+ +EGQ+CR +  +VP  LSL+EI SATMGFN++ +VGEGASAKVYKGSLP GG+VAVKRFE+ D + CL +PF TEFATMVGCLRHKNLVQL GWCCEGNELVLVYE +PNGSL+K+LH++  SS+VLSWKQR+NI+LGVA+AL YLHEECERQIIHRDVKTCN+MLDADFNAKLGDFGLAEVYEHSS  RDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVV+EVATGRKPV +DGTVV D+VW +WE  ++IEAADR+LMGKF++VEMER L+ GL CVHP++ +RP +++AAR++  EAPLP+LP SKPRV + PV P+D+ E  N  G    L  ++  YLTP+S F
Sbjct:   32 TNNVTLSGDAYINNNAISLTHSLTTCPSSSSSSSTTSGIGRAFYAYPIRFLDSKTNATASFLCRFSFSITPSSQLCSC-GDGIAFVITPDVDSLSSSR-GYMGLPEPTSTSKESFFAVEFDTRFDPMVGDINGNHIGIDVNTVVSVASVDVVSKGIDLTSGREITAWIEYRDAIKMIRVWVGYSSTRPPTPLLVAQIDLSKQFKEFMRVGFSASNGQGSSIHIVDRWKFKTFGSLPPGIPMNAVEEGDCFMCSSPEDSSINSGLVDLSHERKTKMVEMALGLGGLAAFLFSIFAFLFVICFMCVKRRKVIARRSREGQTCRVEAKRVPTSLSLAEIRSATMGFNRNRVVGEGASAKVYKGSLPSGGEVAVKRFERADKIGCLRSPFTTEFATMVGCLRHKNLVQLHGWCCEGNELVLVYELMPNGSLNKILHKSFNSSVVLSWKQRLNIVLGVASALAYLHEECERQIIHRDVKTCNIMLDADFNAKLGDFGLAEVYEHSSIARDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVLEVATGRKPVEDDGTVVVDWVWGMWENGKLIEAADRRLMGKFNMVEMERTLMTGLACVHPNHVRRPTMKEAARILNGEAPLPVLPASKPRVNLLPVFPDDSEEIPNFCGLRPSLELEDVQYLTPKSHF 696          

Query:   79 QNLTLFGDASFTDNSITLTKQLTCLSSSSS-------FGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDN-QEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXX-ALGIGGXXXXXXXXXXXXXXICVF-LRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGD-WLSADEAPYLTPRSQF 2034
            +N+TL+GDA  T+N+I+LT+Q TC +SSSS        G+A YLYP+RFLDP+TN+T                     GDG+AFLI+S     SLS+ GYMGLP      + S+ AVEFDTS DPSLGDI+ NHIGID + +VSFA++DA+S G+DL+SG+ ITAWIEY D  K+++VWV Y   RPP+PIL + VDLSE FKE+MHVGFSASNGQGS+ H+V HW+FKT +   SV+P D  ++GDC +CY                       ALG+GG              I  F +++ KG   + KEG+      N+VP RLS++EI +ATMGF++  ++G+GASA V+KG L   G VAVKRF++   ++C  NPF TEFATMVGCLRH+NLVQL+GWCCEG  L LVYEYLPNGSL++VLH+N +S+I L WKQRVNI+LGVA+AL+YLHEECERQIIHRDVK CN++LDA+FNAKLGDFGLAEVYEHSS  R ATIPAGT GYLAPEYVY GVP+VK+DVYSFGVV++EVATG++PV + G V+ D VW+ WEK ++IEAAD KL+G F+ +E+ERML+VGL CVHP++E RP V++AA +++ +APLP+LPQ KP V  + V   D+ ET N+ GD     D+  ++TPR+ F
Sbjct:   23 RNVTLYGDAHLTNNAISLTQQHTCPASSSSSSSSSNGVGKALYLYPIRFLDPITNTTASFFCRFSFSIIRSPLCSS--GDGMAFLITSNADSFSLSK-GYMGLPEPALNPQDSFIAVEFDTSCDPSLGDISSNHIGIDANTIVSFAAIDAVSVGIDLQSGRQITAWIEYSDSSKLIQVWVSYFQVRPPSPILVAQVDLSEHFKEYMHVGFSASNGQGSAVHIVDHWRFKTYATLSSVTPRDTSDKGDCLMCYPENPMYNYGPGTQNGWKKKLLEMALGLGGLAAFTVSLIVVLFVIIFFAIKKGKGVGGRTKEGR-----INRVPRRLSITEIRTATMGFHRSRIIGQGASATVFKGYLSSCGSVAVKRFDQAG-IECARNPFITEFATMVGCLRHENLVQLQGWCCEGTVLALVYEYLPNGSLNEVLHKNSSSAIFLLWKQRVNIVLGVASALSYLHEECERQIIHRDVKACNILLDAEFNAKLGDFGLAEVYEHSSVMRAATIPAGTTGYLAPEYVYYGVPSVKSDVYSFGVVMLEVATGKRPVDDVGAVLVDRVWSFWEKGKLIEAADSKLVGMFNTLEVERMLMVGLSCVHPNHEMRPTVKEAAVILRGQAPLPVLPQRKPAVGFQSVLSEDSDETLNLAGDNSPCTDDVTWMTPRTSF 676          

Query:   70 LTSQNLTLFGDASFTDNSITLTKQLTCL----SSSSSF-----------GRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDN-QEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXX-ALGIGGXXXXXXXXXXXXXXICVFLRRKKGFV--RKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRV 1929
            L ++N+TL+GDA   +N+I+LT+   C     SSSSSF           GRA YLYPVRFLD  T S P                    GDG+AFLI+S     SLS NGYMGLP      + S+ AVEFDTSFDP L DING+HIGID++ VVSFASVDALS G+DLKSGK + AWIEY D  K+++VWV  S  RPP PIL + VDLSE FKEFMHVGF+ASNGQGS+ HL+ HW+FKT   + + + +   E  DCFLCY                       ALG+GG              I +F+ RKK  V  R+ KEGQ   F     P R S+ EI +ATMGF+++ ++GEGASA VYKGSLP  G VAVKRF K + ++C  NPF TEFAT+VGCL+H NLVQL+GWCCE +ELVLVYEYLPNGSL K+LH N +SS  LSWKQR+NI LGVA+AL+YLHEE ERQIIHRDVKTCN+MLD +FNAKLGDFGLAEVYEHSSSTR+ATIPAGTMGYLAPEYVYSGVP+VKTDVYSFGVVV+EVATG++PV +DGTV+ D+VW  WE+ ++IEAAD KL GKF+  EM+RMLLVGL CVHP++E+RP +++AA+++K EAPLP+LP  KP+V
Sbjct:   29 LQAKNVTLYGDAHLRNNAISLTQDHGCSPPPSSSSSSFFFSDPSSYSGVGRALYLYPVRFLDS-TTSIPASFSCRFSFSIIKSPLCSF-GDGMAFLITSNAESFSLS-NGYMGLPGPALNPQDSFVAVEFDTSFDPFLSDINGDHIGIDVNTVVSFASVDALSNGIDLKSGKQMIAWIEYSDIAKLIQVWVSDSQNRPPNPILEARVDLSENFKEFMHVGFTASNGQGSAVHLIDHWRFKTYWSAPAATNVQASEGEDCFLCYLEDSSENGDPTNLDEKTNKMKEIALGLGGLAAFILSIALILAIIFLFVIRKKRVVFGRRTKEGQF--FIHKGGPTRFSIVEIKAATMGFHRNRIIGEGASATVYKGSLPDLGAVAVKRFNKTE-IECCRNPFITEFATIVGCLKHNNLVQLQGWCCEESELVLVYEYLPNGSLAKILHNNTSSSNFLSWKQRMNIALGVASALSYLHEESERQIIHRDVKTCNIMLDEEFNAKLGDFGLAEVYEHSSSTREATIPAGTMGYLAPEYVYSGVPSVKTDVYSFGVVVLEVATGKRPVDDDGTVLVDWVWGFWEQGKLIEAADSKLKGKFNGAEMQRMLLVGLCCVHPNHEERPTIKEAAKILKGEAPLPVLPSRKPKV 661          

Query:   58 SLSFLTSQ-NLTLFGDASFTDNSITLTKQLTCLSS-------SSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEE-SSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRK--KGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSS-----IVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSS--STRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLSADEAPYLTPRSQF 2034
            SL F  SQ NLTL+GDA F  ++I+LT+Q  C  S       SS  GRA Y+YP++FLD  TN+T                     GDG AFLI+S     + S NG++GLP    +   S+ AVEFDT+FDPS GDIN NH+GID++++VS ASVDA+S+G+DLKSG+ +  WIEY D +K++RVWVGYS  +P +P+L++ VDL+ +F+E+MHVGFSASN  GS+FH+V  WKF+T   SH   P  + E+ D  +C+                       +G+                +  F+     +G  R + EG       N+VP RLSL+EI SAT GFN++ +VG GASA VY+GS+P+ G VAVKRF++     C  NPF TEF TM G LRHKNLVQ +GWC EG E  LV+EYLPNGSL   LH+  +S      +VLSWKQRVNIILGVA+ALTYLHEECERQIIHRDVK+CN+MLDA+FNAKLGDFGLAEVYEHS+  S R+AT+PAGTMGYLAPEYVY+GVP+ K+DVYSFGVV++EV TGR+PVG+DG+++ D +W+LWEK ++++  D  L  +FD  EMER+L+VG+VC HPD +KRPRV++A R+I+ EAPLP+LP  +P +RI     +   E   ++ D L  +E P++TP+S F
Sbjct:   23 SLRFSPSQPNLTLYGDAFFRGHTISLTQQQPCFPSPSPRNCSSSGIGRALYVYPIKFLDLSTNTTASFSCRFSFTIIASPSCPF--GDGFAFLIASNADSFTFS-NGFLGLPDPALDPLGSFVAVEFDTAFDPSHGDINDNHVGIDVNSIVSVASVDAISKGIDLKSGREMMVWIEYSDVLKLIRVWVGYSRVKPKSPVLSAQVDLAGKFREYMHVGFSASNALGSAFHIVERWKFRTFG-SH---PDAVQEDDDWLVCFENPGNTRHRYGLDVRVS-----VVGLRIPFWSLLPGLAAVVVLTAFIAYSLIRGKKRIVCEGVGL----NRVPGRLSLAEIKSATSGFNENTIVGHGASATVYRGSIPMVGSVAVKRFDRAHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSDFLHKKPSSDPSEEFVVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKSCNIMLDAEFNAKLGDFGLAEVYEHSAMLSGRNATLPAGTMGYLAPEYVYTGVPSEKSDVYSFGVVILEVCTGRRPVGDDGSILIDLMWSLWEKGKVLDGVDVMLKEEFDAEEMERVLMVGMVCSHPDCDKRPRVKEAVRIIRGEAPLPVLPAKRPLLRI-----HLATEADEMIADSLVGEELPWMTPKSHF 678          

Query:   55 PSLSFLTS---QNLTLFGDASFTDNSITLTKQLTCLSS---------SSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASN-GQGSSFHLVHHWKFKTL-SYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSS-----IVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSS--STRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLSADEAPYLTPRSQF 2034
            P+LS   S    NLTL+GDA F D +I+LT+Q  C  S         SS  GRA Y+YP++FL+P TN+T                     GDG AFLI+S    S +  NG++GLP+    + S+ AVEFDT FDP  GDIN NH+GID++++ S ASVDA+S+G DLKSG+ + AWIEY D +K++RVWVGYS  +P +P+L++ +DLS + KE+MHVGFSASN G GS+ H+V  WKF T  S+S ++   +  +E +C +C                          I                  +      G  ++I EG       N++P RLSL+EI SAT GFN++ +VG+GASA VY+GS+P  G VAVKRF++     C  NPF TEF TM G LRHKNLVQ +GWC EG E  LV+EYLPNGSL + LH+  +S      IVLSWKQRVNIILGVA+ALTYLHEECERQIIHRDVKTCN+MLDA+FNAKLGDFGLAE+YEHS+  + R AT+PAGTMGYLAPEYVY+GVP+ KTDVYSFGVVV+EV TGR+PVG+DGTV+ D +W+LWE  ++++ AD  L  +FD  EMER+L+VG+VC HPD EKRPRV++A R+I+ EAPLP+LP  +P +RIR        E + ++ D L  ++  ++TP+S F
Sbjct:   21 PTLSHRFSPPLHNLTLYGDAFFRDRTISLTQQQPCFPSATTPPSKPTSSGIGRALYVYPIKFLEPSTNTTASFSCRFSFSIISSPSCPF--GDGFAFLITSNAD-SFVFSNGFLGLPNP---DDSFIAVEFDTGFDPGHGDINDNHVGIDVNSIFSVASVDAISKGFDLKSGREMMAWIEYSDVLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGVGSALHIVERWKFTTFESHSDAIQEEEEKDE-ECLVCSGEVFENPMGIHRKGFDFRVSVVGFKIPFWSLLPGMAAIVILVAFIVFSLISG-KKRISEGADTNSGINRMPGRLSLAEIKSATSGFNENTIVGQGASATVYRGSIPSIGSVAVKRFDRDHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEFIVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSALLAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPVGDDGTVLVDLMWSLWETGKVLDGADIMLREEFDAGEMERVLMVGMVCAHPDCEKRPRVKEAVRIIRGEAPLPVLPARRPLLRIR-----SATEAEEMIADGLGREDLTWMTPKSHF 688          

Query:   55 PSLS--FLTSQNLTLFGDASFTDNSITLTKQLTCLSSSSS-----FGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYS-STRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKT--LSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXA---LGIGGXXXXXXXXXXXXXXICVFL--RRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLS-ADEAPYLTPRSQF 2034
            PSLS  FL   N+TL+GDASFT  SITLT++  C SSSS+      GRAFY YPVRFLD LTN+T                     GDG+ FL++S     S+S +GYMGLP+ + E+S + AVEF+          N N IG+D   + S AS +  S G+DLKSGK +   IEY+D  KM+RVW+GY    RPP P+L++ +D+S + KEFM +GF+A   +GS+ + +  W+F+T  L  S   S  D  +EG+C +C+                      +   L  GG              + V    R+K+  V +  E Q CR Q N+VP RLSLSEI SAT  FN + ++GEGASA VY+G +P  G VAVKRF +   L   H PF TEFA+MVGCLRHKNL+QL+GWCCE NELVLVYE++PNGSLDK+LH     +  L+W++R+NI++GV++AL YLHEECE  IIHRDVK+CN+MLDA+FNAKLGDFGLAEV++ +S TRDAT+PAGTMGY APEYVY+G+PTVKTDVYSFGVVV+EVA+GRKP+ E G ++ D+VW+LWEK RI EAAD KLMG+F   EM+RML+VGL CVHPD+EKRPR+RD  RM+K EAPL +LP  KP VRI+ V P    E  N    W +  ++ P+ TPR+ F
Sbjct:   22 PSLSAPFLPINNVTLYGDASFTAKSITLTQERNCSSSSSTPPISGIGRAFYTYPVRFLDSLTNNTASFLCTFSFTILPTPSCPF--GDGMGFLVTSDVDSLSIS-DGYMGLPNPDSEDS-FLAVEFNA---------NDNRIGVDTKEIRSLASTNVDSAGIDLKSGKEMAGRIEYKDSEKMIRVWIGYELQIRPPNPVLSTRIDVSNQLKEFMRIGFTA---KGSAVYSISRWRFRTFGLISSPISSSWDQSDEGNCLMCFPEEEIGGHISDSHHSSSSSGSKSLLKLTYGGLAAIVTLVGCALSVVFVLALRRKKRDRVGETNERQMCRLQGNRVPQRLSLSEIKSATECFNHERIIGEGASAVVYEGEIPSRGSVAVKRFVQGSRLGPSHIPFNTEFASMVGCLRHKNLIQLQGWCCERNELVLVYEFMPNGSLDKILHERSHLTKFLTWERRLNIVIGVSSALMYLHEECENHIIHRDVKSCNIMLDAEFNAKLGDFGLAEVFD-NSKTRDATVPAGTMGYFAPEYVYTGIPTVKTDVYSFGVVVLEVASGRKPIDEGGGLITDWVWDLWEKGRITEAADPKLMGRFQKNEMDRMLIVGLSCVHPDHEKRPRMRDVFRMLKDEAPLLILPPMKPTVRIQSVLPESCEEIMN----WAARMEDTPWSTPRTHF 676          

Query:   55 PSLS--FLTSQNLTLFGDASFTDNSITLTKQLTCLSSS----SSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYS-STRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKT--LSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGI--GGXXXXXXXXXXXXXXICVFL--RRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLS-ADEAPYLTPRSQF 2034
            PSLS  FL   N+TL+GDASFT  SITLT+   C SSS    S  GRAFY YPVRFLD LTN+T                     GDG+AFL++S     S+S +GYMGLP+ + E+S + AVEF+          N N IG+D   + S AS    S G+DLKSGK +   IEY+D  K++RVW+GY    RPP P+L++ +D+S +  EFM +GF+A   +GS+ + +  W+F+T  L  S   S  D  +EG+C +C+                       L +  GG              + V    R+K+  V + KE Q CR Q N+VP RLSLSEI SAT  FN + ++GEGASA VY+G +P  G VAVKRF     L   H PF TEFA+MVGCLRHKNL+QL+GWCCE NELVLVYE++PNGSLDK+LH     +  L+W++R+NI++GV++AL YLH+ECE  IIHRDVK+CN+MLDA+FNAKLGDFGLAEV++ +S TRDAT+PAGTMGY APEYVY+G+PTVKTDVYSFGVVV+EVA+GRKP+ E G ++ D+VW++WEK RI EAAD KLMG+F   EM+RML+VGL CVHPD+EKRPR+RD  RM+K EAPL +LP  KP VR++ + P    E  N    W +  ++ P+ TPR+ F
Sbjct:   22 PSLSVPFLPINNVTLYGDASFTAKSITLTQDRNCSSSSTPPISGIGRAFYTYPVRFLDSLTNNTASFLCTFSFTILPTPSCPF--GDGMAFLVTSDVDSLSIS-DGYMGLPNPDSEDS-FLAVEFNA---------NDNRIGVDTKEIRSLASASVDSAGIDLKSGKEMAGRIEYKDSEKIIRVWIGYELQIRPPNPVLSTRIDVSNQLNEFMRIGFTA---KGSAVYSISRWRFRTFGLISSPISSSWDQSDEGNCLMCFPEEEIGGHISDSHHSSSTSSKSLLKLTYGGLAAIVTLVGCALSVVFVLALRRKKRDRVGENKERQMCRLQGNRVPQRLSLSEIKSATECFNHERIIGEGASAVVYEGEIPSRGSVAVKRFVHGSRLGPSHIPFNTEFASMVGCLRHKNLIQLQGWCCERNELVLVYEFMPNGSLDKILHERSHLTKFLTWERRLNIVIGVSSALMYLHDECENHIIHRDVKSCNIMLDAEFNAKLGDFGLAEVFD-NSKTRDATVPAGTMGYFAPEYVYTGIPTVKTDVYSFGVVVLEVASGRKPIDEGGGLITDWVWDMWEKGRITEAADPKLMGRFQKNEMDRMLIVGLSCVHPDHEKRPRMRDVFRMLKDEAPLLILPPMKPTVRLQSILPESCEEIMN----WAARMEDTPWSTPRTHF 674          

Query:   55 PSLSFLTS---QNLTLFGDASFTDNSITLTKQLTCLSS---------SSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQ----GSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFV--------RKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSS-----IVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSS--STRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLSADEAPYLTPRSQF 2034
            P+LS   S    NLTL+GDA F D +I+LT+Q  C  S         SS  GRA Y+YP++F +P TN+T                     GDG AFLI+S    S +  NG++GLP+ +    S+ AVEFDT FDP  GDIN NH+GID+++V S +SVDALS+G DLKSG+ + AWIEY D +K++RVWVGYS  +P +PILA+ +DLS + KE+MHVGFSASN      GS+ H+V  WKF T + SHS    D I+E D                            + + G              I V +    GF+        +KI E +       ++P RLSL+EI SAT+GFN++ +VG+GASA VY+GS+P  G VAVKRF++     C  NPF TEF TM G LRHKNLVQ +GWC EG E  LV+EYLPNGSL + LH+  +S      IVLSWKQRVNIILGVA+ALTYLHEECERQIIHRDVKTCN+MLD++FNAKLGDFGLAE+YEH++  S R AT+PAGTMGYLAPEYVY+GVP+ KTDVYSFGVVV+EV TGR  VG DGT + D++WNLWE  + +  AD  L   FD  EMER+L+VG+VC H D EKRP+V++A R+I+ EAPLP+LP  KP +RIR        E + ++ D L  ++ P++TP+S F
Sbjct:   25 PTLSHRFSPPLHNLTLYGDAYFRDRTISLTRQQPCFPSATTPPSNPSSSGIGRALYVYPIKFSEPSTNTTASFSCRFSFSIIASPSCPF--GDGFAFLITSNAD-SFVFSNGFLGLPNPHD---SFIAVEFDTRFDPGHGDINDNHVGIDVNSVFSVSSVDALSKGFDLKSGREMMAWIEYSDVLKLIRVWVGYSRVKPTSPILATQIDLSGKVKEYMHVGFSASNAAASVGGSALHIVERWKFTTFA-SHS----DAIQEEDS-------EEEEEEVSRNPIRPKGFGFRVSVVGFKIPFWSLLPGLAAIVVLV----GFIVFSLIVGKKKITE-EGADTGLTRMPGRLSLAEIKSATLGFNENTIVGQGASATVYRGSIPSIGSVAVKRFDREHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEFIVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDSEFNAKLGDFGLAEIYEHNALLSGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRMAVGNDGTGLVDFMWNLWETGKFLTGADIMLKEDFDAEEMERVLMVGMVCTHADCEKRPKVKEAVRIIRGEAPLPVLPAKKPLLRIRSAI-----EAEEMIADDLVGEDLPWMTPKSNF 687          

Query:   55 PSLSFLTS---QNLTLFGDASFTDNSITLTKQLTCLSS---------SSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASN-GQGSSFHLVHHWKFKTL-SYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSS-----IVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSS--STRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKPRVRIRPVCPNDTPETQNVVGDWLSADEAPYLTPRSQF 2034
            P+LS   S   QNLTL+GDA F D +I+LT+Q  C  S         SS  GRA Y+YP++FL+P TN+T   S    FS     S     GDG AFLI+S    S +  NG++GLP+ +    S+ AVEFDT FDP  GDIN NH+GID+S++ S +SVDA+S+G DLKSGK + AWIEY D +K++RVWVGYS  +P +P+L++ +DLS + KE+MHVGFSASN G GS+ H+V  WKF+T  S+S ++   +  ++ +C +C G+ S   K+  +     ++  + L I   +     A    +V  +      G  ++I E         ++P RLSL+EI SAT GFN++ +VG+GASA VY+GS+P  G VAVKRF++     C  NPF TEF TM G LRHKNLVQ +GWC EG E  LV+EYLPNGSL + LH+  +S      IVLSWKQRVNIILGVA+ALTYLHEECERQIIHRDVKTCN+MLDA+FNAKLGDFGLAE+YEHS+  + R AT+PAGTMGYLAPEYVY+GVP+ KTDVYSFGVVV+EV TGR+PVG+DG V+ D +W+ WE  ++++ AD  L  +FD  EMER+L+VG+VC HPD EKRPRV+DA R+I+ EAPLP+LP  +P +RIRP       E + ++ D L  ++ P++TP+S F
Sbjct:   22 PTLSHRFSPPLQNLTLYGDAFFRDRTISLTQQQPCFPSVTTPPSKPSSSGIGRALYVYPIKFLEPSTNTT--ASFSCRFSFSIIASPSCPFGDGFAFLITSNAD-SFVFSNGFLGLPNPDD---SFIAVEFDTRFDPVHGDINDNHVGIDVSSIFSVSSVDAISKGFDLKSGKKMMAWIEYSDVLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGIGSALHIVERWKFRTFGSHSDAIQEEEEEKDEECLVCSGEVSENPKEIHRKGFNFRVTVVGLKIPVWSLLPGLAAIVILVAFIVFSLICG-KKRISEEADSNSGLVRMPGRLSLAEIKSATSGFNENAIVGQGASATVYRGSIPSIGSVAVKRFDREHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSALLAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPVGDDGAVLVDLMWSHWETGKVLDGADIMLREEFDAEEMERVLMVGMVCAHPDSEKRPRVKDAVRIIRGEAPLPVLPARRPLLRIRPAN-----EAEEMIVDGLVGEDLPWMTPKSHF 690          

Query:   70 LTSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYF-AVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDAL-SRGVDLKSGKIITAWIEYRDDMKMVRVWVGYS-----STRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTL---------SYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRK----IKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDV-AVKRFEKVDDLDCLHNPF--ATEFA---TMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHR-NLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGED----GTV-VGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKP 1923
             T +NLT  GD+   +  + LT++L    +SS  G   Y  P+RF DP +N+T SFS  FSF++ +    P+S+GDG+AF +S     +  S  GY+GL + +Q   + F A+EFDT  DP   D NGNHIG+D+ ++ S ++ D L S  +DLKSGK IT+WI+Y++D++++ V++ Y+     + +P  P+L+  +DLS      M+VGFS S    +  HL+ +W FKT          ++ H+VS   ++ +    +                +R+    +A+G+G         ++  V+IC+ L     F  K    +K  +  + +        S  E+ +AT GF+   ++G GA   VY+      G + AVKR          HN     TEF    +++ CLRHKNLVQL+GWC E  EL+LVYE++PNGSLDK+L++ + T ++ L W  R+NI +G+A+AL+YLH ECE+Q++HRD+KT N+MLD +FNA+LGDFGLA + EH  S   +T+ AGTMGYLAPEY+  G  T KTD +S+GVV++EVA GR+P+ ++     TV + D+VW L  + R++EA D +L G+FD   M+++LLVGL C HPD  +RP +R   +++  E     +P+ KP
Sbjct:   38 FTIRNLTFLGDSHLRNGVVGLTRELGVPDTSS--GTVIYNNPIRFYDPDSNTTASFSTHFSFTVQNLNPDPTSAGDGLAFFLSHDND-TLGSPGGYLGLVNSSQPMKNRFVAIEFDTKLDPHFNDPNGNHIGLDVDSLNSISTSDPLLSSQIDLKSGKSITSWIDYKNDLRLLNVFLSYTDPVTTTKKPEKPLLSVNIDLSPFLNGEMYVGFSGSTEGSTEIHLIENWSFKTSGFLPVRSKSNHLHNVSDSSVVNDDPVVI-------------PSKKRRHRHNLAIGLG---------ISCPVLICLALFVFGYFTLKKWKSVKAEKELKTELITGLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVSSGTISAVKR--------SRHNSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTEHDKSPV-STLTAGTMGYLAPEYLQYGTATEKTDAFSYGVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVLEAVDERLKGEFDEEMMKKLLLVGLKCAHPDSNERPSMRRVLQILNNEIEPSPVPKMKP 653          

Query:   73 TSQNLTLFGDASFT-DNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEE--SSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDA-------LSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIK-EGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGD--VAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDG----TVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLP 1902
             S NLTL G A      +I LT +     +    G AFY  P+RF     N     S   SF+I   P   +  G G+AF I+ T        + Y+GL + ++    S +FAVEFDT  D    DIN NH+GID++++ S  S  A         + + L  G++I AWI+Y  + K + V +   S +P   +L+  VDLS    + M+VGFSAS G               L+ SH +   +    G+ F           +     +++K    +L +G      +   A  V   +F+      VRK+K E +   ++ +  P R S  E+  AT GF    L+G G   KVYKG LP G D  VAVKR             F +E ++ +G LRH+NLVQL GWC   ++L+LVY+++PNGSLD  L  +    ++L+WKQR  II GVA+ L YLHE  E+ +IHRD+K  NV+LD++ N ++GDFGLA++YEH S    AT   GT GYLAPE   SG  T  TDVY+FG V++EVA GR+P+         V+ D+VW+ W+   I +  DR+L G+FD  E+  ++ +GL+C +   E RP +R     ++K+ P P
Sbjct:   34 ASPNLTLNGVAEIAPTGAIRLTTE-----TQRVIGHAFYSLPIRFKPIGVNRA--LSFSTSFAIAMVPEFVTLGGHGLAFAITPTPDLRGSLPSQYLGLLNSSRVNFSSHFFAVEFDTVRDLEFEDINDNHVGIDINSMESSISTPAGYFLANSTKKELFLDGGRVIQAWIDYDSNKKRLDVKLSPFSEKPKLSLLSYDVDLSSVLGDEMYVGFSASTG--------------LLASSHYILGWNFNMSGEAF---SLSLPSLPRIPSSIKKRKKKRQSLILGVSLLCSLLIFAVLVAASLFV------VRKVKDEDRVEEWELDFGPHRFSYRELKKATNGFGDKELLGSGGFGKVYKGKLP-GSDEFVAVKRISHESRQGV--REFMSEVSS-IGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGSLDMYLF-DENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDP-GATRVVGTFGYLAPELTKSGKLTTSTDVYAFGAVLLEVACGRRPIETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNGEFDEEEVVMVIKLGLLCSNNSPEVRPTMRQVVMYLEKQFPSP 624          

Query:  973 RKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGD-VAVKRFEKVDDLDCLH------NPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTV----VG------DYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLLPQSKP 1923
            ++++   S   +  K P   S  E+ + T  FN+  ++G GA   VY+G LP  GD VAVKR        C H      N F +E  +++G LRH+NLV+L+GWC E  E++LVY+ +PNGSLDK L     S   L W  R  I+LGVA+AL YLH ECE Q+IHRDVK+ N+MLD  FNAKLGDFGLA   EH  S  +AT+ AGTMGYLAPEY+ +G  + KTDV+S+G VV+EV +GR+P+ +D  V    VG      ++VW L+++ ++  AAD +L GKFD  EM R+L+VGL C HPD   RP +R   +M+  EA +P++P+S+P
Sbjct:  345 KRVERSDSFASEIIKAPKEFSYKELKAGTKNFNESRIIGHGAFGVVYRGILPETGDIVAVKR--------CSHSSQDKKNEFLSEL-SIIGSLRHRNLVRLQGWCHEKGEILLVYDLMPNGSLDKAL---FESRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDESFNAKLGDFGLARQIEHDKSP-EATVAAGTMGYLAPEYLLTGRASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQRHNVGVNPNLVEWVWGLYKEGKVSAAADSRLEGKFDEGEMWRVLVVGLACSHPDPAFRPTMRSVVQMLIGEADVPVVPKSRP 665          

Query:   61 LSFLTSQNLTLFGDASFTDNSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHW 732
             S L   NL L GDA  ++  + LT+ L+  +S +  G+  Y  P+RF  P T+     S    FS   +   PSS G G+AF+IS       ++  G +GL   N   S + AVEFDT  D    DIN NH+G D++ VVS  S D  +  +DLKSG  I +WIEY    ++  V V YS+ +P  PIL+  +DL     +FM VGFS S    +  H +  W
Sbjct:   26 FSTLAISNLKLLGDARLSNGIVGLTRDLSVPNSGA--GKVLYSNPIRFRQPGTHFP--TSFSSFFSFSITNVNPSSIGGGLAFVISPDANSIGIA-GGSLGLTGPNGSGSKFVAVEFDTLMDVDFKDINSNHVGFDVNGVVSSVSGDLGTVNIDLKSGNTINSWIEYDGLTRVFNVSVSYSNLKPKVPILSFPLDLDRYVNDFMFVGFSGSTQGSTEIHSIEWW 244          

Query:  292 GDGIAFLISSTTRFSSLSRNGYMGL--PSDNQEESSY-FAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSR-------GVDLKSGKIITAWIEYRDDMKMVRVWVG-YSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGG-DVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPV-----GEDGTVVGDYVWNLWEKNRIIEAADRKLMGK-FDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLL 1908
            G GIAF+++ T        + Y+GL   S+N  ++++ FAVEFDT      GD N NH+GIDL+ + S     A  R        + L S K I  WI+Y +    + V V  + S +P  P+++ + DLS    E M+VGFS++ G   S H +  W F+     +  +PM  + +      +    I    K               IG     +    +   +    +RRKK +  ++ + ++  F  N    R    E+  AT GF +  L+G G   +VY+G LP    +VAVKR     D       F  E  + +G + H+NLV L G+C    EL+LVY+Y+PNGSLDK L+ N  ++  L WKQR  II GVA+ L YLHEE E+ +IHRDVK  NV+LDADFN +LGDFGLA +Y+H S  +   +  GT+GYLAPE+  +G  T  TDVY+FG  ++EV +GR+P+      +D  ++ ++V++LW +  I+EA D KL    +D+ E+E +L +GL+C H D   RP +R   + ++ +  LP L
Sbjct:  102 GHGIAFVVAPTLGLPFALPSQYIGLFNISNNGNDTNHIFAVEFDTIQSSEFGDPNDNHVGIDLNGLRSANYSTAGYRDDHDKFQNLSLISRKRIQVWIDYDNRSHRIDVTVAPFDSDKPRKPLVSYVRDLSSILLEDMYVGFSSATGSVLSEHFLVGWSFRL----NGEAPMLSLSKLPKLPRFEPRRISEFYK---------------IGMPLISLSLIFSIIFLAFYIVRRKKKYEEELDDWET-EFGKN----RFRFKELYHATKGFKEKDLLGSGGFGRVYRGILPTTKLEVAVKRVSH--DSKQGMKEFVAEIVS-IGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPETT--LDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHV-VGTLGYLAPEHSRTGRATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLRGDMALPEL 628          

Query:  292 GDGIAFLISSTTRF-SSLSRNGYMGL---PSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDA----LSRGVD----LKSGKIITAWIEYRDDMKMVRVWVGYSST------------RPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVL-HRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDG----TVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLL 1908
            G G+AF++S T    S+ S N  +G+    +DN+  +  FAVE DT+ +    D  GN +GID++++VS  S DA      +G +    L SGK I  WI+Y    K++ V +    T            +P  P+L+  ++LSE F E M+VGFS S G   S   +  W FK    + S   +D+       L     S       ++          L +GG                V+L +KK +   +++     ++    P R S   +  AT GF ++ L+G G   KVYKG LP G  +AVKR     D +     +  E A+M G LRHKNLV L G+C    EL+LVY+Y+PNGSLD  L H+N      L+W QRVNII GVA+AL YLHEE E+ ++HRD+K  N++LDAD N KLGDFGLA  ++   +  +AT   GT+GY+APE    GV T  TDVY+FG  ++EV  GR+PV  D      ++  +V +  +++ + +  D KL+  F V E + +L +G++C   + E RP +R   + ++    +P +
Sbjct:  101 GHGMAFVVSPTKDLRSNGSANSNLGIFNRANDNKTATHIFAVELDTNQNSESFDKGGNDVGIDINSIVSVESADASYFNARKGKNISLPLASGKSILVWIDYDGIEKVLNVTLAPVQTPKPDSPYFSSFIKPKVPLLSRSINLSEIFTETMYVGFSGSTGSIKSNQYILGWSFKQGGKAES---LDISR-----LSNPPPSPKRFPLKEVLGATISTIAFLTLGG---------------IVYLYKKKKYAEVLEQ-----WEKEYSPQRYSFRILYKATKGFRENQLLGAGGFGKVYKGILPSGTQIAVKRV--YHDAEQGMKQYVAEIASM-GRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNKLKD--LTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNL-EATRVVGTIGYMAPELTAMGVTTTCTDVYAFGAFILEVVCGRRPVDPDAPREQVILVKWVASCGKRDALTDTVDSKLI-DFKVEEAKLLLKLGMLCSQINPENRPSMRQILQYLEGNVSVPAI 633          

Query:   61 LSFLTSQNLTLFGDASFTDNSITLTKQLTCL---------SSSSSFGRAFYLYPVRFLD--PLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGL--PSDNQEESSY-FAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDA--LSR------GVDLKSGKIITAWIEYRDDMKMVRVWVGYSSTRPPTPILASLVDLSERF-KEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVG-----DYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLP 1902
            +SF TS   T F    F  +++ L    T L          S    G AF   P+ F    PL+ ST        F     P      G GI F+IS T  F+      YMG+   S N   SS+ FAVE DT  +P   + N NHIGID++N +S  S  A   S+       ++L SGK I  W++Y  ++  V V     + +P  P+L+  ++LSE F +  + VGF+A+ G   S+H +  W F T              E    L +       + + +  + +    IAL +      +++ +  AV+  V+  RKK +  ++ E    ++ T+    R S   +  AT GF+KD  +G G   +VY+G LPL   VAVKR     D +     F  E  +M   L+H+NLV L G+C    EL+LV EY+PNGSLD+ L  +   S VLSW QR  I+ G+A+AL YLH E E+ ++HRD+K  NVMLDA+ N +LGDFG+A  ++H  +    T   GT+GY+APE +  G  T+ TDVY+FGV ++EVA GRKPV E G  V       +V   W+K+ +++A D +L  +F   E+E ++ +GL+C +   E RP +      +    PLP
Sbjct:   17 ISFSTSSKDTSFVFNGFGQSNLALDGSATLLPNGLLQLAKDSQHQMGHAFIKKPIDFSSSKPLSFST-------HFVCALVPKPGFEGGHGITFVISPTVDFTRAQPTRYMGIFNASTNGSPSSHLFAVELDTVRNPDFRETNNNHIGIDVNNPISVESAPASYFSKTAQKNVSINLSSGKPIQVWVDYHGNVLNVSV-APLEAEKPSLPLLSRSMNLSEIFSRRRLFVGFAAATGTSISYHYLLGWSFST------------NRELSQLLDFSKLPQVPRPRAEHKKVQFALIIALPV------ILAIVVMAVLAGVYYHRKKKYA-EVSEPWEKKYGTH----RFSYKSLYIATKGFHKDRFLGRGGFGEVYRGDLPLNKTVAVKRVSH--DGEQGMKQFVAEVVSM-KSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDD--QSPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGNAA-TTAAVGTVGYMAPELITMGASTI-TDVYAFGVFLLEVACGRKPV-EFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLSGNLPLP 619          

Query:  172 GRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLISSTTRFSSLSRNGYMGL---PSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDA-------LSRGVDLKSGKIITAWIEYRDDMKMVRVWVG-YSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLP-LGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPV-----GEDGTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLPLL 1908
            G AFY  P+RF D    +    S   SF           SG GIAF+++        + + Y+GL    ++  E +  FAVE DT       D N NH+GID++++ S  S  A         + + L S K +  W++Y      + V +  ++  +P  P++ ++ DLS    + M+VGFS++ G   S H +  W   +   +    P+ +                S+         K       IG     +    +   ++C  +RR++ F  +++E     F  N    R    ++  AT GF +  L+G G    VYKG +P    ++AVKR             F  E  + +G + H+NLV L G+C    EL+LVY+Y+PNGSLDK L+   T  + L+WKQR+ +ILGVA+ L YLHEE E+ +IHRDVK  NV+LD + N +LGDFGLA +Y+H S  +   +  GT+GYLAPE+  +G  T+ TDV++FG  ++EVA GR+P+      ++  ++ D+V+ LW K  I+ A D  +  + D  E+E +L +GL+C H D   RP +R     ++ +A LP L
Sbjct:   64 GHAFYTKPIRFKDSPNGTV--SSFSTSFVFAIHSQIAILSGHGIAFVVAPNASLPYGNPSQYIGLFNLANNGNETNHVFAVELDTILSTEFNDTNDNHVGIDINSLKSVQSSPAGYWDEKGQFKNLTLISRKPMQVWVDYDGRTNKIDVTMAPFNEDKPTRPLVTAVRDLSSVLLQDMYVGFSSATGSVLSEHYILGW---SFGLNEKAPPLAL----------------SRLPKLPRFEPKRISEFYKIGMPLISLFLIFSFIFLVCYIVRRRRKFAEELEE-WEKEFGKN----RFRFKDLYYATKGFKEKGLLGTGGFGSVYKGVMPGTKLEIAVKRVSHESRQGM--KEFVAEIVS-IGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYN--TPEVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTHV-VGTLGYLAPEHTRTGRATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLRGDAKLPEL 627          

Query:  292 GDGIAFLISS--TTRFSSLSRNGYMGL---PSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVS--------FASVDALSRGVDLKSGKIITAWIEYRDDMKMVRVWVG------------YSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICV------FLRRKKGFV---RKIKEGQSCRFQTNKV-PMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRFEKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNELVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGED----GTVVGDYVWNLWEKNRIIEAADRKLMGKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKKEAPLP 1902
            G G+AF+++     R+S  + + Y+GL    +DN+ E+   AVE DT+  P   + + NH+GID+++++S        F+  +  +    L S K I  WI+Y    K++ V V              SS +P  P+L+  +++SE F   M VGFS S G   S   +  W FK    + S+    +++  +                     +      + I                ICV      FL    GF+   +K K  +      N+  P R S   +  A  GF ++ L+G G   KVYKG LP G  +AVKR     + +     +A E A+M G LRHKNLVQL G+C    EL+LVY+Y+PNGSLD  L  N      L+W QRVNII GVA+AL YLHEE E+ ++HRD+K  N++LDAD N +LGDFGLA  ++   + + AT   GT+GY+APE    GV T KTD+Y+FG  ++EV  GR+PV  D       +  +V    +++ +++  D KL G F   E + +L +G++C   + E RP +R   + ++  A +P
Sbjct:   99 GQGMAFVVAPFMDIRYSGDAAS-YLGLFNRKNDNKTENHILAVELDTNSSPEAIEDSDNHVGIDINSIISEDSANASYFSGTEGKNISFRLASEKSILVWIDYNGTEKLLNVTVAPVPTPKPALPYLSSSIKPRKPLLSRFINISEIFNGTMFVGFSGSTGTVKSDQYILGWSFKKGGQAESLDLSKILDPPNRPPPPSSPPPPPPPPPTPPTSRSKDSKNIII----------------ICVTVTSIAFLLMLGGFLYLYKKKKYAEVLEHWENEYSPQRYSFRNLYKAIRGFRENRLLGAGGFGKVYKGELPSGTQIAVKRV--YHNAEQGMKQYAAEIASM-GRLRHKNLVQLLGYCRRKGELLLVYDYMPNGSLDDYLF-NKNKLKDLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDRGENLQ-ATRVVGTIGYMAPELTAMGVATTKTDIYAFGSFILEVVCGRRPVEPDRPPEQMHLLKWVATCGKRDTLMDVVDSKL-GDFKAKEAKLLLKLGMLCSQSNPESRPSMRHIIQYLEGNATIP 651          

Query:   64 SFLTSQNLTLFGDASFTD--NSITLTKQLTCLSSSSSFGRAFYLYPVRFLDPLTNSTPXXXXXXXXXXXXXXXXXXXXGDGIAFLI---SSTTRFSSLSRNGYMGLPSDNQEESSYFAVEFDTSFDPSLGDINGNHIGIDLSNVVSFASVDALSRG---------VDLKSGKIITAWIEYRD---DMKMVRVWVGYSSTRPPTPILASLVDLSERFKEFMHVGFSASNGQGSSFHLVHHWKFKTLSYSHSVSPMDMIEEGDCFLCYXXXXXXXXXXXXXXXXXXXXXXALGIGGXXXXXXXXXXXXXXICVFLRRKKGFVRKIKEGQSCRFQTNKVPMRLSLSEITSATMGFNKDMLVGEGASAKVYKGSLPLGGDVAVKRF-----EKVDDLDCLHNPFATEFATMVGCLRHKNLVQLKGWCCEGNE-LVLVYEYLPNGSLDKVLHRNLTSSIVLSWKQRVNIILGVAAALTYLHEECERQIIHRDVKTCNVMLDADFNAKLGDFGLAEVYEHSSSTRDATIPAGTMGYLAPEYVYSGVPTVKTDVYSFGVVVIEVATGRKPVGEDGTVVGDYVWNLWEKNRIIEAADRKLM--GKFDVVEMERMLLVGLVCVHPDYEKRPRVRDAARMIKK 1887
            S  T+ N  L G+A+     + +TLT Q T      S GR   LYP R     ++++P          ++     S  G G AF+    S T+  SS    G     ++    S  FAVEFD   +    DIN NH+G+D++++ S AS  A   G         + L SG+   AWIE+     ++ M R     SS +P  P+++  ++L+    + M VGF+AS GQ     LV   +  + S+S+S   +     GD  +     S        +  +         I GV++ VV  ++   ++C ++ R++   R+  EG    ++T   P R+   ++  AT GF+ + ++G G ++KVY+G L  G +VAVKR      E V       + F  E +++ G LRHKN+V LKGW  +G E L+L+YEY+ NGS+DK   R    + +L+W++R+ +I  +A+ + YLHE  E +++HRD+K+ NV+LD D NA++GDFGLA++   S      T   GT GY+APE V +G  + +TDVYSFGV V+EV  GR+P+ E    + +++W L EK+++++  D ++   G F V E+E  L +GL+CVHPD   RP++R   +++++
Sbjct:   30 SNFTTTNTLLLGNATVKSPPSILTLTNQTTF-----SIGRG--LYPSRINASSSSASPLPFATSFIFSMAPFKHLSP-GHGFAFVFLPFSETSAASSSQHLGLFNFTNNGDPNSRIFAVEFDVFANQEFNDINDNHVGVDVNSLTSVASETAGFYGGRDGQRFTELKLNSGENYQAWIEFNGSAINVTMARA----SSRKPIRPLISIPLNLTGVLLDDMFVGFTASTGQ-----LVQSHRILSWSFSNSNFSI-----GDALITRNLPSFKLSGDSVLKSKGF-------IAGVSSGVVLLVSVIGLLCFYVVRRR---RQRLEGDVEDWETEYWPHRVQYKDVLEATKGFSDENMIGYGGNSKVYRGVLE-GKEVAVKRIMMSPRESVGAT----SEFLAEVSSL-GRLRHKNIVGLKGWSKKGGESLILIYEYMENGSVDK---RIFDCNEMLNWEERMRVIRDLASGMLYLHEGWETKVLHRDIKSSNVLLDKDMNARVGDFGLAKLQNTSKEMVSTTHVVGTAGYMAPELVKTGRASAQTDVYSFGVFVLEVVCGRRPIEEGREGIVEWIWGLMEKDKVVDGLDERIKANGVFVVEEVEMALRIGLLCVHPDPRVRPKMRQVVQILEQ 621