Ca_01504, Ca_01504_v1.0_kabuli (mRNA) Cicer arietinum

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITR-THTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPN-DNKLIVVEYMPNGSLHDLLHSTT----RPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRR 1077
            MGYL CN +SA+A CD + W  N R+   +P  R    +  F Y ++  ATN FSA ++LGKGSHGRVY+A L+    +G L+ AVK T +T+                N  S V+NEIEILS+V    +VN+IGYC D     KL+VVEYMPNG+LHD LHS +    R   W RRI+ ALQ+A AV  LH +   VIHRDIKS NVLID D  AR+ DFGLAL G+V+D R+K TPPAGTLGYLDP YLAP DL+AKSDVFSFGILLLEIISGR AID+NYSP  +VDWAVPLI+RGD+  +CD +I                     STA+KRP M+EVVEC+K  R+    SP W  LRRR
Sbjct:    1 MGYLSCNGESAVAICDTYNW--NPRRRSKVPEKRHPPKLRVFNYDELAVATNGFSANNFLGKGSHGRVYKAVLD----DGKLLAAVKRTTITTTVGNN----------NNNVSQVDNEIEILSRVRHRWMVNLIGYCVDHRRKTKLLVVEYMPNGTLHDQLHSRSSLDSRLSSWNRRIKHALQIAIAVHALHTAETQVIHRDIKSCNVLIDGDGNARLADFGLALIGNVDDERLKYTPPAGTLGYLDPSYLAPADLTAKSDVFSFGILLLEIISGREAIDLNYSPSCIVDWAVPLIKRGDYDAICDLKIKNRPYYAVIRKLAVMAARCVRSTAKKRPDMLEVVECLKTVRQL---SPAWNKLRRR 346          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSI------PITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTT-----RPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVV 1011
            MGYL C A SA+A         +   +         PI     +  FL+ D+ +AT  F   + LG+GSHG VY+A +      G+  +AVK    +                   +    NE EILS++ SPR VN++G+  D +   L+VVE+M NGSL+D++HS T         W++RI+ ALQ+AKAV  LH+   P+IHRDIKS+NVL+D++  A++GDFGLA+R +V+D +VK TPPAGT+GYLDP Y+    LS K+DVFSFGILLLEIISGR AIDV YSP  +VDWA+P+I+RG   G+ D RIG P+D +              +  EKRPGM EVV
Sbjct:    1 MGYLSCKAGSAVAIAVSSAASTSGSTSSKASAPPESPIEDRPRLRRFLHRDLESATGGFDINNLLGRGSHGSVYKAVI------GSRHIAVKRPSKSR----------------EISREFHNEFEILSRIRSPRFVNLLGFSADNSKEPLLVVEFMGNGSLYDVIHSDTVLNSGAISSWSKRIKIALQIAKAVHLLHSQETPIIHRDIKSANVLMDKNLNAKLGDFGLAIRCNVDDQKVKSTPPAGTMGYLDPDYVTADRLSTKTDVFSFGILLLEIISGRKAIDVRYSPSFIVDWAIPMIKRGKIGGIYDPRIGPPIDVSVRNHLGLVAAKCVRTCREKRPGMEEVV 326          

Query:  118 EFLYTDIVTATNAFSAESYLGKGSHGRVYRATLN--TVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVP-SPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRP-PGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALR-GHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLC-DRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEV-VECIKLARKRISESPLWRSLRRRVARVE 1092
            EF Y  +VTA + FS    +GKGSHG VY+A L+   V      VVA+KT    S            +     T  +ENEI+++S +P  P +++ +G+     + KL+VVEYMPN SL+ LLH +T P P W +RI  ALQ+A AV  LH     +IHRDIKS N+L D +W+A++ DFGLA+  G  + +R     PAGT+GYLDPCY  P +LS K+DV+S+G++LLEI+S R AIDV+ SP S+VDWAVPLI+ G    +C     G+ + +               S  E RP   E+  E +    + +   PLW S+ RRV +++
Sbjct:    3 EFDYDKLVTAIDRFSPSKLIGKGSHGYVYKALLHHQDVDETRQRVVAIKTPSSLSPSSPSSSS----SSKSEQTKKLENEIDVMSSLPYHPHVLSFLGHA----EKKLMVVEYMPNESLYQLLHVSTDPLPTWLKRIEIALQIASAVHFLHEHG--IIHRDIKSENILFDSNWEAKLADFGLAVDFGGDKKIR---PAPAGTIGYLDPCYTLPENLSMKTDVYSYGVVLLEIVSCRKAIDVSRSPASIVDWAVPLIKEGRIGEICGGGGGGSGVFRGMSLRLLRMAARCVSSDVESRPCFGEITAEIVACLAEPLKSLPLWMSVLRRVVKLK 321          

Query:  118 EFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLH----STTRPPGWTRRIRFALQVAKAVRTLHA-SNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESP 1053
            EF Y ++  AT  FS +S +GKGS   V++  L         VVAVK     S                  +    NE+++LS++    L+N++GYC D ++ +L+V E+M +GSL+  LH    +  +   W RR+  A+Q A+ +  LH  + PPVIHRDIKSSN+LID D  ARV DFGL++ G  +        PAGTLGYLDP Y     L+ KSDV+SFG++LLEI+SGR AID+ +   ++V+WAVPLI+ GD   + D  +  P D                   + RP M +V   ++ A   +  SP
Sbjct:  492 EFSYEELEQATGGFSEDSQVGKGSFSCVFKGILRD-----GTVVAVKRAIKASDVK-------------KSSKEFHNELDLLSRLNHAHLLNLLGYCEDGSE-RLLVYEFMAHGSLYQHLHGKDPNLKKRLNWARRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEGNIVEWAVPLIKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTALEHALALLMGSP 789          

Query:  121 FLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP----GWTRRIRFALQVAKAVRTLHA-SNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESP 1053
            F Y ++  A + F  ES +GKGS   VY+  L          VAVK   ++S                  ++    E+++LS++    L++++GYC +  + +L+V E+M +GSLH+ LH   +       W +R+  A+Q A+ +  LH  + PPVIHRDIKSSN+LID +  ARV DFGL+L G V+        PAGTLGYLDP Y     L+ KSDV+SFG+LLLEI+SGR AID++Y   ++V+WAVPLI+ GD   L D  +  P +                   + RP M +V   ++ A  ++  +P
Sbjct:  500 FTYEELEKAADGFKEESIVGKGSFSCVYKGVLRD-----GTTVAVKRAIMSSDKQKN-------------SNEFRTELDLLSRLNHAHLLSLLGYCEECGE-RLLVYEFMAHGSLHNHLHGKNKALKEQLDWVKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEEHNARVADFGLSLLGPVDSGSPLAELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVLLLEILSGRKAIDMHYEEGNIVEWAVPLIKAGDINALLDPVLKHPSEIEALKRIVSVACKCVRMRGKDRPSMDKVTTALERALAQLMGNP 796          

Query:  121 FLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVN--YSPPSVVDWAVPLIRR----GDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIK 1023
            F Y ++  ATN FS  + LG+G  G V++  L + K      VAVK  K                G G      + E+EI+S+V    LV++IGYC      +L+V E++PN +L   LH   RP   W+ R++ AL  AK +  LH   NP +IHRDIK+SN+LID  ++A+V DFGLA      +  V  T   GT GYL P Y A G L+ KSDVFSFG++LLE+I+GR  +D N  Y   S+VDWA PL+ R    GDF GL D ++G   D+                +A +RP M ++V  ++
Sbjct:  268 FTYEELSRATNGFSEANLLGQGGFGYVHKGILPSGKE-----VAVKQLK---------------AGSGQGEREFQAEVEIISRVHHRHLVSLIGYCM-AGVQRLLVYEFVPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCNPKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVS-TRVMGTFGYLAPEYAASGKLTEKSDVFSFGVVLLELITGRRPVDANNVYVDDSLVDWARPLLNRASEEGDFEGLADSKMGNEYDREEMARMVACAAACVRHSARRRPRMSQIVRALE 554          

Query:  115 TEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSP---PSVVDWAVPLIRR----GDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECI 1020
            T F Y ++   T  FS  + LG+G  G VY+  LN  K     +VAVK  K+               G G      + E+EI+S+V    LV+++GYC   ++ +L++ EY+PN +L   LH   RP   W RR+R A+  AK +  LH   +P +IHRDIKS+N+L+D +++A+V DFGLA         V  T   GT GYL P Y   G L+ +SDVFSFG++LLE+I+GR  +D  Y P    S+V+WA PL+ +    GDF+ L DRR+     +                +  KRP MV+VV  +
Sbjct:  339 THFTYEELTDITEGFSKHNILGEGGFGCVYKGKLNDGK-----LVAVKQLKV---------------GSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSE-RLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVS-TRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVD-QYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVVRAL 626          

Query:   73 RKNKSIP-----ITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVN--YSPPSVVDWAVPL----IRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIK 1023
            R +K++P     +   H  T F Y ++  ATN FS  + LG+G  G VY+  LN    NGN  VAVK  K+               G        + E+ I+SQ+    LV+++GYC      +L+V E++PN +L   LH   RP   W+ R++ A+  +K +  LH + NP +IHRDIK++N+LID  ++A+V DFGLA      +  V  T   GT GYL P Y A G L+ KSDV+SFG++LLE+I+GR  +D N  Y+  S+VDWA PL    +   +F GL D ++    D+                TA +RP M +VV  ++
Sbjct:  151 RDDKALPAPIGLVLGIHQST-FTYGELARATNKFSEANLLGEGGFGFVYKGILN----NGN-EVAVKQLKV---------------GSAQGEKEFQAEVNIISQIHHRNLVSLVGYCI-AGAQRLLVYEFVPNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEAKVADFGLAKIALDTNTHVS-TRVMGTFGYLAPEYAASGKLTEKSDVYSFGVVLLELITGRRPVDANNVYADDSLVDWARPLLVQALEESNFEGLADIKLNNEYDREEMARMVACAAACVRYTARRRPRMDQVVRVLE 457          

Query:  112 ITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHASN-PPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVE--DVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVN--YSPPSVVDWAVPLIRRGDFAGLCDRRI--GTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRR 1074
            + EF   ++  AT+ FS   +LG GS G VY+  L+  +      VA+K  +LT+                +  S   NE+E +S++    LV ++G+  D  + +++V EYM NGSL D LH+    P  W  R+  AL  A+ ++ LH    PPVIHRDIKSSN+L+D  W A+V DFGL+  G  E  DV       AGTLGY+DP Y     L+ KSDV+SFG++LLE++SG  AI  N   +P ++V++ VP I   +   + D+RI   TP +                  + KRP MVEVV  ++ A      +P   ++ R
Sbjct:  428 LMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVLSDGRH-----VAIKRAELTNPTLSGTTMRHRRA---DKDSAFVNELESMSRLNHKNLVRLLGFYED-TEERILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPVIHRDIKSSNILLDATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPEYYKFQQLTTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRILDQRIPPPTPYEIEAVAHVGYLAAECLMPCSRKRPSMVEVVSKLESALAACLTAPKTETVSR 747          

Query:  121 FLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVN--YSPPSVVDWAVPLIRR----GDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIK 1023
            F Y ++  ATN FS  + LG+G  G V++  L   K      VAVK  K                G        + E+ I+S+V    LV ++GYC   +  +L+V E++PN +L   LH   RP   W+ R++ A+  AK +  LH + NP +IHRDIK+SN+LID  ++A+V DFGLA      +  V  T   GT GYL P Y + G L+ KSDVFSFG++LLE+I+GR  IDVN  ++  S+VDWA PL+ +    G+F  + D+++    D+               STA +RP M +V   ++
Sbjct:  342 FNYEELSRATNGFSEANLLGQGGFGYVFKGMLRNGKE-----VAVKQLK---------------EGSSQGEREFQAEVGIISRVHHRHLVALVGYCI-ADAQRLLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCNPKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVS-TRVMGTFGYLAPEYASSGKLTEKSDVFSFGVVLLELITGRRPIDVNNVHADNSLVDWARPLLNQVSELGNFEVVVDKKLNNEYDKEEMARMVACAAACVRSTAPRRPRMDQVARVLE 628          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLT--SXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVARVESAQPLMKWE 1119
            MGYLFCNA+SAIATCDPHYWDL KR +K++   RTH I EFLYTD+VTAT++FSAESYLGKGSHGRVY+A LN  K N  +VVAVKTTKLT  S           CTGCGNCTSP ENEIEILSQVP+PRLVN+IGYCTDPN NKLIVVEYMPNGSLHDLLHS+++PPGWTRR RFALQVAKAVRTLH SNPPVIHRDIKSSNVLID+D+KAR+GDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAP DLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIR+GDF G+CDRRIG P D                STAEKRPGMVEVVEC+KLARKR   SP+W S RRRV RVE+AQPLM+ E
Sbjct:    1 MGYLFCNAESAIATCDPHYWDLKKR-SKTLTTNRTHIIKEFLYTDLVTATDSFSAESYLGKGSHGRVYKAKLNGDKDN--IVVAVKTTKLTTKSKHSHINGNNKNCTGCGNCTSPAENEIEILSQVPNPRLVNLIGYCTDPNGNKLIVVEYMPNGSLHDLLHSSSKPPGWTRRFRFALQVAKAVRTLHGSNPPVIHRDIKSSNVLIDQDFKARLGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPEDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRKGDFVGICDRRIGAPSDLVMLRQIAVIAARCVRSTAEKRPGMVEVVECLKLARKRFHSSPIWCSWRRRVTRVENAQPLMRCE 372          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVARVESAQPL 1107
            MGYL CNA S+IATC PH+           P+  T  I  F Y DIV A N FS++++LG+GSHGRVYRATL+     G L+ AVKTTKL +           CTGCGNCTSP ENEIEILSQ+PSPRLVN+IG+ TDPN NKL+VVEYMPNGSLHDLLHS  +PPGW RR+RFALQVAKAVR LH+SNPPVIHRD+KSSNVLID++W AR+GDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAP DLSAKSDVFSFGILLLEIISGRNAIDVN+SPPSVVDWAVPLI+ GDFAG+CDRRIG P D                STAEKRP M EVVEC+ LARKRI  SP+W SLRRRVARVESA P+
Sbjct:   16 MGYLSCNAHSSIATCHPHHK----------PLAAT-PIRHFPYADIVAAANGFSSDTFLGRGSHGRVYRATLDA----GKLLAAVKTTKLVATSTSKNHATK-CTGCGNCTSPAENEIEILSQIPSPRLVNLIGFSTDPNGNKLLVVEYMPNGSLHDLLHSVKKPPGWNRRVRFALQVAKAVRELHSSNPPVIHRDVKSSNVLIDQEWNARLGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPEDLSAKSDVFSFGILLLEIISGRNAIDVNFSPPSVVDWAVPLIKIGDFAGICDRRIGPPPDPAVVRQLAVLAARCVRSTAEKRPSMAEVVECLNLARKRIRASPIWNSLRRRVARVESALPV 368          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVARVESAQPLMKWE 1119
            MGYL CNA+SAIATCDPH+     +K+K +  T    I  F Y DI  A N FSA+++LG+GSHGRVYRATL+     G L+ AVKTTKL             CTGCGNCTSP ENEIEILSQVPSPR VN++G+ TDPN NKLIVVEYMPNGSLHDLLHS  +PPGW+ R+RFALQVAKAVR LH+SNPPVIHRD+KSSNVLID +W AR+GDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAP DLSAKSDVFSFGILLLEIISGRNAIDVN+SPPSVVDWAVPLI+ GDFAG+CDRRIG   D                STAEKRP M EVVEC+ LARKR   SP+W +LRRRVA VESA P+  WE
Sbjct:    1 MGYLSCNAESAIATCDPHF-----KKHKPLAAT---PIRHFHYADIAAAANGFSADTFLGRGSHGRVYRATLD----GGKLLAAVKTTKLAGTTSKNHASK--CTGCGNCTSPAENEIEILSQVPSPRFVNLLGFSTDPNGNKLIVVEYMPNGSLHDLLHSVKKPPGWSLRVRFALQVAKAVRELHSSNPPVIHRDVKSSNVLIDEEWNARLGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPEDLSAKSDVFSFGILLLEIISGRNAIDVNFSPPSVVDWAVPLIKLGDFAGICDRRIGPQPDPAVLRQLAVLAARCVRSTAEKRPSMAEVVECLNLARKRNRASPIWNNLRRRVASVESALPV--WE 357          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRK--NKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDP-NDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWR---------SLRRRVARVES 1095
            MGYL CNA+SAIATCDP+ WD  ++   NK+ P  +   I  F Y D+V ATN F+AES+LGKGSHG VY+A L+     G+LV AVK TK +             T         ENEIEILS+V  PRLVN+IG+C+D  ND KLIVVEYMPNGSL+DLLH  +RPPGWTRRIRF L VAKAV+ LH+S+PPVIHRDIKSSNVLID+DW AR+GD GLALRGHVEDVR+KCTPPAGTLGYLDP YLAPGDLSAKSDVFSFGILLLEI+SGRNAIDVNYSPPSVVDWAVP+I+RGDFAG+CD+RIG P D                STAEKRP M EVVEC+K+  KRI    +W+          + RRVA+ +S
Sbjct:    1 MGYLSCNAESAIATCDPYNWDRRRKPKTNKTKPNNKPIKIRHFYYDDLVAATNGFAAESFLGKGSHGSVYKAFLD----GGSLVAAVKKTKSSQT-----------TSSSASLHNAENEIEILSRVHHPRLVNLIGFCSDSANDTKLIVVEYMPNGSLYDLLHLNSRPPGWTRRIRFGLHVAKAVQALHSSSPPVIHRDIKSSNVLIDKDWNARLGDLGLALRGHVEDVRIKCTPPAGTLGYLDPGYLAPGDLSAKSDVFSFGILLLEILSGRNAIDVNYSPPSVVDWAVPIIKRGDFAGICDQRIGPPADPAVIRHVAVLAAKCVRSTAEKRPTMAEVVECLKVMIKRIHAPSIWKCEGEGEGEEMIDRRVAKSKS 362          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVAR 1086
            MGYL CNA+SAIATCDP+ WD NKRK           IT F Y D+ +ATN FSAES+LGKGS+G VYRA L+    +G L+ AVK                 C+ C N TSP +NEIEILS+V +PRLVN++G+  D N+ KLIVVE+MPNGSL+D+LHS+ RPP W RR+R+A Q+AKAV +LH+SNPPVIHRDIKSSNVL+D  W AR+GDFGLALRGHVEDVRV+CTPPAGTLGYLDP YLAPGDLS KSDVFSFGILLLE+ISGRNAIDVNYSPPSVVDWAVPLI+  +F+ +CD RIG P D                STAEKRP   EVV+C++  RK +   P+W ++RRRV R
Sbjct:    1 MGYLSCNAESAIATCDPYIWD-NKRK--------PFQITNFSYADLESATNGFSAESFLGKGSYGSVYRALLH----HGKLIAAVKRAIGPQQHNNKCASCTNCSTCSNSTSPADNEIEILSRVRNPRLVNLLGFSVDRNEKKLIVVEFMPNGSLYDILHSSPRPPSWRRRVRWASQIAKAVESLHSSNPPVIHRDIKSSNVLLDGKWNARLGDFGLALRGHVEDVRVRCTPPAGTLGYLDPGYLAPGDLSTKSDVFSFGILLLEMISGRNAIDVNYSPPSVVDWAVPLIKHTNFSAICDPRIGEPEDPRVIRQLAVLAARCVRSTAEKRPAATEVVDCLRNVRKMVQSPPIWGNVRRRVQR 349          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVARVESAQP 1104
            M YL CNA+SAIA CDP+    N +++ + P+     + +F Y  +V ATN FSA+ +LGKGSHG VY+A L+    +G L+ AVK T  T             + C  CTSP ENEIEILS++  PRLVN+IGYCTD    KL+VVEYM NGSL+ LLH   RPPGWTRR+R+ALQVAKAV  LH ++PPVIHRD+KSSNVLID  W+AR+GDFGLALRGHVEDVRVKCTPPAGTLGYLDP YLAP DLS KSDVFSFGILLLEIISGRNAIDVNYSPPS+V+WA+PLI+RGD++ +CD RIG+P+D                STAEKRPGM EVVE +K   KR+    LW  LR RV       P
Sbjct:    1 MDYLCCNAESAIAACDPYN---NSKRSSNKPVK----LRDFTYHQLVKATNGFSADCFLGKGSHGTVYKANLD----DGKLIAAVKKTYPTPSTTNH-------SNCSTCTSPAENEIEILSRIQHPRLVNLIGYCTD---RKLLVVEYMQNGSLYSLLHCCPRPPGWTRRVRYALQVAKAVHALHTAHPPVIHRDVKSSNVLIDDKWRARLGDFGLALRGHVEDVRVKCTPPAGTLGYLDPGYLAPADLSTKSDVFSFGILLLEIISGRNAIDVNYSPPSIVEWALPLIKRGDYSIICDHRIGSPVDPGIIKILAVLAARCVRSTAEKRPGMAEVVEGLKFVSKRVHAPLLWNRLRMRVGETRQFDP 347          

Query:   25 DSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVAR 1086
            +SAIATCDP+ WD NKRK           IT F Y D+ +ATN FSAES+LGKGS+G VYRA L+    +G L+ AVK                 C+ C N TSP +NEIEILS+V +PRLVN++G+  D N+ KLIVVE+MPNGSL+D+LHS+ RPP W RR+R+A Q+AKAV +LH+SNPPVIHRDIKSSNVL+D  W AR+GDFGLALRGHVEDVRV+CTPPAGTLGYLDP YLAPGDLS KSDVFSFGILLLE+ISGRNAIDVNYSPPSVVDWAVPLI+  +F+ +CD RIG P D                STAEKRP   EVV+C++  RK +   P+W ++RRRV R
Sbjct:  205 ESAIATCDPYIWD-NKRK--------PFQITNFSYADLESATNGFSAESFLGKGSYGSVYRALLH----HGKLIAAVKRAIGPQQHNNKCASCTNCSTCSNSTSPADNEIEILSRVRNPRLVNLLGFSVDRNEKKLIVVEFMPNGSLYDILHSSPRPPSWRRRVRWASQIAKAVESLHSSNPPVIHRDIKSSNVLLDGKWNARLGDFGLALRGHVEDVRVRCTPPAGTLGYLDPGYLAPGDLSTKSDVFSFGILLLEMISGRNAIDVNYSPPSVVDWAVPLIKHTNFSAICDPRIGEPEDPRVIRQLAVLAARCVRSTAEKRPAATEVVDCLRNVRKMVQSPPIWGNVRRRVQR 545          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVARVESAQPLMKWE 1119
            MGYL CNA+SAIATCD   W+  K +  + P T    I EF Y+D+ +ATNAFS ++ LGKGSHG VYRA L+  K     +VAVK  KLT                 +  SP ENEIEILS+V  PRLVN++GY  D N NKLIVVE+MPNGSL++LLHS ++PP WTRR+RFALQ+A+ V  LH+SNPPVIHRDIKSSN+LID ++ AR+GDFGL+LRGHVEDV VK TPPAGTLGYLDP YLAP DLS KSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLI+ G++  + D R+ +P D                 TA KRP M EVVE +KL  KR+S SP+W ++ RRV RV  +  ++K+E
Sbjct:    1 MGYLSCNAESAIATCDS--WNFKKTRTHNKPFT----IREFSYSDLHSATNAFSQDNLLGKGSHGYVYRAHLHQTKLT---LVAVKRGKLTEPRN------------SSSNSPAENEIEILSRVHHPRLVNLLGYAVDSNQNKLIVVEFMPNGSLYELLHSHSKPPNWTRRVRFALQIARGVHFLHSSNPPVIHRDIKSSNILIDGNFSARLGDFGLSLRGHVEDVVVKSTPPAGTLGYLDPAYLAPSDLSTKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIKSGEYTDIYDPRLTSPEDDGALRQLAVVAARCVRKTAAKRPAMAEVVEWLKLVYKRMS-SPIWNNIGRRVGRVRESTRVVKYE 351          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHT-----ITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRVARVESAQPLMKWE 1119
            MGYL CNA+SAIATCD      N +K      T+THT     I E+ Y+D+ +ATNAFS ++ LGKGSHG VYRA L+ VK +   VVAVK  KLT                 +  SP ENEIEILS+V  PRLVN++GY  D N NKLIVVE+MPNGSL++LLHS ++PP W RR+RFA Q+A+ V  LH+SNPPVIHRDIKSSN+LID ++ AR+GDFGL+LRG+VEDV VK TPPAGTLGYLDP YLAP DLS KSDVFS+GILLLEIISGRNAIDVNYSPPSVVDWAVPLI+ G+++ + D R+ +P D                 TA KRP M EVVE +K   KR+S SP+W ++ RRV RV  +  ++K+E
Sbjct:    1 MGYLSCNAESAIATCD----SCNFKK------TKTHTNKSLKIREYSYSDLHSATNAFSQDNLLGKGSHGYVYRAHLHQVKLS---VVAVKRGKLTEPRN------------SSSNSPAENEIEILSRVHHPRLVNLLGYAVDENQNKLIVVEFMPNGSLYELLHSHSKPPNWIRRVRFASQIARGVHFLHSSNPPVIHRDIKSSNILIDGNFSARLGDFGLSLRGNVEDVVVKSTPPAGTLGYLDPAYLAPSDLSTKSDVFSYGILLLEIISGRNAIDVNYSPPSVVDWAVPLIKSGEYSEIYDPRLTSPEDDGALRQLAIVAARCVRKTAAKRPAMAEVVEWLKQVYKRMS-SPIWNNIGRRVGRVRESTRVVKYE 352          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVP-SPRLVNIIGYCTDP------NDNKLIVVEYMPNGSLHDLLHST---TRPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRRV 1080
            M YL CNA+SAIATCDPH   L K+K    P  +   +  F Y+DI+ ATN FSA+++LGKGSHG VY+A  +     G LV AVK TK                          NEIEILS +  +PRLVN+IG+C D       N+NKLIVVEYMPNGSLH+LLHST    RPP WT R+RFA+QVAKAVR LH+S PPVIHRDIKSSNVLID  W AR+GDFGLA+RGHV D RV   PPAGTLGYLDPCYLAPGDLS+KSDVFSFG+LLLEI SGR+A+DV +SPPSV+DWAVPL+RRG+F  +CD RIG P D                ST E+RP MVEV+EC+   RK      +W+ ++RRV
Sbjct:    1 MPYLTCNAESAIATCDPH--SLKKKKKPKSP-AQAQPVRHFAYSDILDATNNFSADTFLGKGSHGTVYKAAFH----GGALVAAVKITK----------------------PKTSNEIEILSHLKKNPRLVNLIGFCNDQTQTNNINNNKLIVVEYMPNGSLHELLHSTKKPVRPPSWTARVRFAVQVAKAVRLLHSSEPPVIHRDIKSSNVLIDEKWNARLGDFGLAVRGHVADSRV---PPAGTLGYLDPCYLAPGDLSSKSDVFSFGVLLLEIASGRHALDVRHSPPSVLDWAVPLVRRGEFKEICDPRIGAPPDMAAFRRMAVLAARCVRSTPERRPSMVEVLECLTAVRKCFRAPVMWKRIKRRV 338          

Query:    1 MGYLFCNADSAIATCDPHYWDLNKRKNKSIPITRTH-TITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPN-DNKLIVVEYMPNGSLHDLLHSTTRPPG----WTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESPLWRSLRRR 1077
            MGYL CN +SA+A CD + W  N R+   +P  R    +  F Y ++  ATN FSA ++LGKGSHGRVY+A L+    +G L+ AVK T +T+   +N+ N           S V+NEIEILS+V    +VN+IGYC D     KL+VVEYMPNG+LHD LHS +        W RRI+ ALQ+A AV  LH +   VIHRDIKS NVLID D  AR+ DFGLAL G+V+D R+K TPPAGTLGYLDP YLAP DL+AKSDVFSFGILLLEIISGR AID+NYSP  +VDWAVPLI+RGD+  +CD +I       V+R LAV+AARCVRSTA+KRP M+EVVEC+K  R+    SP W  LRRR
Sbjct:    1 MGYLSCNGESAVAICDTYNW--NPRRRSKVPEKRHPPKLRVFNYDELAVATNGFSANNFLGKGSHGRVYKAVLD----DGKLLAAVKRTTITTTVGNNNNN----------VSQVDNEIEILSRVRHRWMVNLIGYCVDHRRKTKLLVVEYMPNGTLHDQLHSRSSLDSRLSSWNRRIKHALQIAIAVHALHTAETQVIHRDIKSCNVLIDGDGNARLADFGLALIGNVDDERLKYTPPAGTLGYLDPSYLAPADLTAKSDVFSFGILLLEIISGREAIDLNYSPSCIVDWAVPLIKRGDYDAICDLKIKNRPYYAVIRKLAVMAARCVRSTAKKRPDMLEVVECLKTVRQL---SPAWNKLRRR 346          

Query:   91 PITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTT-----RPPGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVV 1011
            PI     +  FL+ D+ +AT  F   + LG+GSHG VY+A +      G+  +AVK    +                   +    NE EILS++ SPR VN++G+  D +   L+VVE+M NGSL+D++HS T         W++RI+ ALQ+AKAV  LH+   P+IHRDIKS+NVL+D++  A++GDFGLA+R +V+D +VK TPPAGT+GYLDP Y+    LS K+DVFSFGILLLEIISGR AIDV YSP  +VDWA+P+I+RG   G+ D RIG P+D +V   L ++AA+CVR+  EKRPGM EVV
Sbjct:   37 PIEDRPRLRRFLHRDLESATGGFDINNLLGRGSHGSVYKAVI------GSRHIAVKRPSKSR----------------EISREFHNEFEILSRIRSPRFVNLLGFSADNSKEPLLVVEFMGNGSLYDVIHSDTVLNSGAISSWSKRIKIALQIAKAVHLLHSQETPIIHRDIKSANVLMDKNLNAKLGDFGLAIRCNVDDQKVKSTPPAGTMGYLDPDYVTADRLSTKTDVFSFGILLLEIISGRKAIDVRYSPSFIVDWAIPMIKRGKIGGIYDPRIGPPIDVSVRNHLGLVAAKCVRTCREKRPGMEEVV 326          

Query:  112 ITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLN--TVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVP-SPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRP-PGWTRRIRFALQVAKAVRTLHASNPPVIHRDIKSSNVLIDRDWKARVGDFGLALR-GHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRR 876
            + EF Y  +VTA + FS    +GKGSHG VY+A L+   V      VVA+KT    S +  + ++    +     T  +ENEI+++S +P  P +++ +G+     + KL+VVEYMPN SL+ LLH +T P P W +RI  ALQ+A AV  LH     +IHRDIKS N+L D +W+A++ DFGLA+  G  + +R     PAGT+GYLDPCY  P +LS K+DV+S+G++LLEI+S R AIDV+ SP S+VDWAVPLI+ 
Sbjct:    1 MKEFDYDKLVTAIDRFSPSKLIGKGSHGYVYKALLHHQDVDETRQRVVAIKTPSSLSPSSPSSSS----SSKSEQTKKLENEIDVMSSLPYHPHVLSFLGHA----EKKLMVVEYMPNESLYQLLHVSTDPLPTWLKRIEIALQIASAVHFLHEHG--IIHRDIKSENILFDSNWEAKLADFGLAVDFGGDKKIR---PAPAGTIGYLDPCYTLPENLSMKTDVYSYGVVLLEIVSCRKAIDVSRSPASIVDWAVPLIKE 247          

Query:  115 TEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVN--YSPPSVVDWAVPLIRR----GDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIK 1023
            + F Y ++  ATN FS  + LG+G  G V++  L + K      VAVK  K                G G      + E+EI+S+V    LV++IGYC      +L+V E++PN +L   LH   RP   W+ R++ AL  AK +  LH   NP +IHRDIK+SN+LID  ++A+V DFGLA      +  V  T   GT GYL P Y A G L+ KSDVFSFG++LLE+I+GR  +D N  Y   S+VDWA PL+ R    GDF GL D ++G   D+  +  +   AA CVR +A +RP M ++V  ++
Sbjct:  266 STFTYEELSRATNGFSEANLLGQGGFGYVHKGILPSGK-----EVAVKQLK---------------AGSGQGEREFQAEVEIISRVHHRHLVSLIGYCM-AGVQRLLVYEFVPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCNPKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHV-STRVMGTFGYLAPEYAASGKLTEKSDVFSFGVVLLELITGRRPVDANNVYVDDSLVDWARPLLNRASEEGDFEGLADSKMGNEYDREEMARMVACAAACVRHSARRRPRMSQIVRALE 554          

Query:  121 FLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP----GWTRRIRFALQVAKAVRTLHA-SNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESP 1053
            F Y ++  A + F  ES +GKGS   VY+  L          VAVK   ++S  + N             ++    E+++LS++    L++++GYC +  + +L+V E+M +GSLH+ LH   +       W +R+  A+Q A+ +  LH  + PPVIHRDIKSSN+LID +  ARV DFGL+L G V+        PAGTLGYLDP Y     L+ KSDV+SFG+LLLEI+SGR AID++Y   ++V+WAVPLI+ GD   L D  +  P +   L+ +  +A +CVR   + RP M +V   ++ A  ++  +P
Sbjct:  500 FTYEELEKAADGFKEESIVGKGSFSCVYKGVLRD-----GTTVAVKRAIMSSDKQKN-------------SNEFRTELDLLSRLNHAHLLSLLGYCEECGE-RLLVYEFMAHGSLHNHLHGKNKALKEQLDWVKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEEHNARVADFGLSLLGPVDSGSPLAELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVLLLEILSGRKAIDMHYEEGNIVEWAVPLIKAGDINALLDPVLKHPSEIEALKRIVSVACKCVRMRGKDRPSMDKVTTALERALAQLMGNP 796          

Query:  118 EFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLH----STTRPPGWTRRIRFALQVAKAVRTLHA-SNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESP 1053
            EF Y ++  AT  FS +S +GKGS   V++  L     +G +V   +  K +   K               +     E+++LS++    L+N++GYC D ++ +L+V E+M +GSL+  LH    +  +   W RR+  A+Q A+ +  LH  + PPVIHRDIKSSN+LID D  ARV DFGL++ G  +        PAGTLGYLDP Y     L+ KSDV+SFG++LLEI+SGR AID+ +   ++V+WAVPLI+ GD + L D  +  P D   L+ +A +A +CVR  A+ RP M +V   ++ A   +  SP
Sbjct:  491 EFSYEELEQATGGFSEDSQVGKGSFSCVFKGILR----DGTVVAVKRAIKASDVKKS--------------SKEFHTELDLLSRLNHAHLLNLLGYCEDGSE-RLLVYEFMAHGSLYQHLHGKDPNLKKRLNWARRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEGNIVEWAVPLIKAGDISALLDPVLSPPSDLEALKKIAAVACKCVRMRAKDRPSMDKVTTALERALALLMGSP 788          

Query:   73 RKNKSIP-----ITRTHTITEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVN--YSPPSVVDWAVPL----IRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIK 1023
            R +K++P     +   H  T F Y ++  ATN FS  + LG+G  G VY+  LN    NGN  VAVK  K+               G        + E+ I+SQ+    LV+++GYC      +L+V E++PN +L   LH   RP   W+ R++ A+  +K +  LH + NP +IHRDIK++N+LID  ++A+V DFGLA      +  V  T   GT GYL P Y A G L+ KSDV+SFG++LLE+I+GR  +D N  Y+  S+VDWA PL    +   +F GL D ++    D+  +  +   AA CVR TA +RP M +VV  ++
Sbjct:  151 RDDKALPAPIGLVLGIHQST-FTYGELARATNKFSEANLLGEGGFGFVYKGILN----NGN-EVAVKQLKV---------------GSAQGEKEFQAEVNIISQIHHRNLVSLVGYCI-AGAQRLLVYEFVPNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEAKVADFGLAKIALDTNTHV-STRVMGTFGYLAPEYAASGKLTEKSDVYSFGVVLLELITGRRPVDANNVYADDSLVDWARPLLVQALEESNFEGLADIKLNNEYDREEMARMVACAAACVRYTARRRPRMDQVVRVLE 457          

Query:  118 EFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLH----STTRPPGWTRRIRFALQVAKAVRTLHA-SNPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSPPSVVDWAVPLIRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIKLARKRISESP 1053
            EF Y ++  AT  FS +S +GKGS   V++  L     +G +V   +  K +   K               +    NE+++LS++    L+N++GYC D ++ +L+V E+M +GSL+  LH    +  +   W RR+  A+Q A+ +  LH  + PPVIHRDIKSSN+LID D  ARV DFGL++ G  +        PAGTLGYLDP Y     L+ KSDV+SFG++LLEI+SGR AID+ +   ++V+WAVPLI+ GD   + D  +  P D   L+ +A +A +CVR   + RP M +V   ++ A   +  SP
Sbjct:  492 EFSYEELEQATGGFSEDSQVGKGSFSCVFKGILR----DGTVVAVKRAIKASDVKKS--------------SKEFHNELDLLSRLNHAHLLNLLGYCEDGSE-RLLVYEFMAHGSLYQHLHGKDPNLKKRLNWARRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEGNIVEWAVPLIKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTALEHALALLMGSP 789          

Query:  115 TEFLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRPP-GWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNYSP---PSVVDWAVPLIRR----GDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECI 1020
            T F Y ++   T  FS  + LG+G  G VY+  LN  K     +VAVK  K+               G G      + E+EI+S+V    LV+++GYC   +  +L++ EY+PN +L   LH   RP   W RR+R A+  AK +  LH   +P +IHRDIKS+N+L+D +++A+V DFGLA         V  T   GT GYL P Y   G L+ +SDVFSFG++LLE+I+GR  +D  Y P    S+V+WA PL+ +    GDF+ L DRR+     +  +  +   AA CVR +  KRP MV+VV  +
Sbjct:  339 THFTYEELTDITEGFSKHNILGEGGFGCVYKGKLNDGK-----LVAVKQLKV---------------GSGQGDREFKAEVEIISRVHHRHLVSLVGYCI-ADSERLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHV-STRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVD-QYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVVRAL 626          

Query:  121 FLYTDIVTATNAFSAESYLGKGSHGRVYRATLNTVKGNGNLVVAVKTTKLTSXXXXXXXXXXXCTGCGNCTSPVENEIEILSQVPSPRLVNIIGYCTDPNDNKLIVVEYMPNGSLHDLLHSTTRP-PGWTRRIRFALQVAKAVRTLHAS-NPPVIHRDIKSSNVLIDRDWKARVGDFGLALRGHVEDVRVKCTPPAGTLGYLDPCYLAPGDLSAKSDVFSFGILLLEIISGRNAIDVNY---SPPSVVDWAVPL----IRRGDFAGLCDRRIGTPLDQTXXXXXXXXXXXXXXSTAEKRPGMVEVVECIK 1023
            F Y D+  AT+ FS  + LG+G  G V+R  L  V G    +VA+K  K               +G G      + EI+ +S+V    LV+++GYC      +L+V E++PN +L   LH   RP   W++R++ AL  AK +  LH   NP  IHRD+K++N+LID  ++A++ DFGLA      D  V  T   GT GYL P Y + G L+ KSDVFS G++LLE+I+GR  +D +       S+VDWA PL    +  G+F GL D R+    D   +  +   AA  VR +A++RP M ++V   +
Sbjct:  131 FTYEDLSKATSNFSNTNLLGQGGFGYVHRGVL--VDGT---LVAIKQLK---------------SGSGQGEREFQAEIQTISRVHHRHLVSLLGYCI-TGAQRLLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCNPKTIHRDVKAANILIDDSYEAKLADFGLARSSLDTDTHV-STRIMGTFGYLAPEYASSGKLTEKSDVFSIGVVLLELITGRRPVDKSQPFADDDSIVDWAKPLMIQALNDGNFDGLVDPRLENDFDINEMTRMVACAAASVRHSAKRRPKMSQIVRAFE 418