Ca_04834, Ca_04834_v1.0_kabuli (mRNA) Cicer arietinum

Query:    1 MEDGALTSSTTMMEAPQPDENSMDFDYVSELLLDGCWLEASADGSDFL-LQSSPFSNPLFDP-SFTWPSLDNIDPPDNVDRHKSQDAS-LGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQ-HRRMAASLDGDFFFNET-----MGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVG---IREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSN 2685
            MED  L S   +M+A          D++  LLLDGCWLE + DGS+FL +  S  S   FDP SF W                +QD S L T      +   D         F+      +  RWWIGP    G GGS + E+L++A++ IKD+   +  LIQ+WVPVNRG  R  LT  + PFS +     LA YREISV Y FSAE++DSK L AGLPGRV+  K+PEWTPDVRFF+S+EYPRV HAQ+CD+ GTLA+PVFEQGS+ CLGVIEVVMTT+      ELE++C+AL+ VDLRS+      ++K  D SY+ ALPEI+ +LR ACE HKLPLAQTW+ C QQ K GCRH+D+NY+HC+S ++ ACY+GD +VR FHEAC EHHLLKGQGVAG AF+TN PCFS+D+++  K +YPLSHHA ++GL  AVAIRLR I++ S D+VLEFFLP DC+D  EQ+KML +LS I+  V R+LR +T+KELE+     +EV++  +         SEL  +    ASL+     N T     +G  F    +  +   LK   +   + +++ E +  SS G   + EK+R KADKTITL VLRQYFAGSLKDAAKNIGVC TTLKRICRQHGI+RWPSRKIKKVGHSLQK+Q VIDSVQG S    I SFY+   +L S            +Q  +Q +  T P P  +                             +   N+ A+   P      V   LK+  SE EL+S   D     +     S E + +            T+  +SQ +D  R+KV+YG+EK R RM  +    D++ EIG+RF++ DMS++D+KYLD+D EWVLLTCD D+EEC+DVC+++   TIKL LQ SS+
Sbjct:    1 MEDSFLQSENVVMDA----------DFMDGLLLDGCWLETT-DGSEFLNIAPSTSSVSPFDPTSFMWSP--------------TQDTSALCTSGVVSQMYGQDCVERSSLDEFQ------WNKRWWIGP----GGGGSSVTERLVQAVEHIKDYTTARGSLIQLWVPVNRGGKR-VLTTKEQPFSHDPLCQRLANYREISVNYHFSAEQDDSKAL-AGLPGRVFLGKLPEWTPDVRFFKSEEYPRVHHAQDCDVRGTLAIPVFEQGSKICLGVIEVVMTTEMVKLRPELESICRALQAVDLRSTELPIPPSLKGCDLSYKAALPEIRNLLRCACETHKLPLAQTWVSCQQQNKSGCRHNDENYIHCVSTIDDACYVGDPTVREFHEACSEHHLLKGQGVAGQAFLTNGPCFSSDVSNYKKSEYPLSHHANMYGLHGAVAIRLRCIHTGSADFVLEFFLPKDCDDLEEQRKMLNALSTIMAHVPRSLRTVTDKELEEE----SEVIEREEIVTPKIENASELHGNSPWNASLEEIQRSNNTSNPQNLGLVFDGGDKPNDGFGLKRGFDYTMDSNVN-ESSTFSSGGFSMMAEKKRTKADKTITLDVLRQYFAGSLKDAAKNIGVCPTTLKRICRQHGIQRWPSRKIKKVGHSLQKIQRVIDSVQGVSGPLPIGSFYANFPNLVSQ-----------SQEPSQQAKTTPPPPPPVQ-------LAKSPVSSYSHSSNSSQCCSSETQLNSGATTDPP---STDVGGALKKTSSEIELQSSSLDETILTL----SSLENIPQ-----------GTNLLSSQDDDFLRIKVSYGEEKIRLRMRNSRRLRDLLWEIGKRFSIEDMSRYDLKYLDEDNEWVLLTCDEDVEECVDVCRTTPSHTIKLLLQASSH 829          

Query:   52 PDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPS-FTWPSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDS----KDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLS-ANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVG----IREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASS-TFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVS-LNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFI--RSSL 2703
            P + +MD  ++  LLL+GCWLE + D S+FL  S   S   FDPS F W      D  +++ +   QD       E  S+ + + G +   +            RWWIGP   SG  G  ++E+L++A+  IKDF   +  LIQ+WVPV+RG  R  LT  + PFS +     LA YREIS  YQFS E+EDS    +DLV GLPGRV+  KVPEWTPDVRFF+++EYPRV HAQ+CD+ GTLA+PVFEQGS+ CLGVIEVVMTTQ    S +LE++C+AL+ VDLRS+      ++K  D SY+ ALPEI+ +LR ACE HKLPLAQTW+ C++Q K GCRH+D+NY+HC+S ++ ACY+GD +VR FHEAC EHHLLKGQGV G AF+TN PCFS+D++S  K +YPLSHHA +FGL   VAIRLR I++ S D+VLEFFLP +C D  EQ+KML +LS I+  V R+LR +T KELE+   S  +EV++        G T  ++++      +       + +G  F   T +   L     +E G+  S++ E N  SS      + EK+R KA+K ITL VLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI+RWPSRKIKKVGHSLQK+Q VIDSV+G S     I SFY+       PNL+ +   S+L Q     + L+    P + SP  +                          H+++  S++  ++ ED  D                    K  ++ RS   ET   H               +SQ++D  RVKV+Y +EK RF+M  +   +D++ EI +RF++ D+S++D+KYLD+D EWVLL CD D+EEC+DVC+S    TIKL LQ SS+++  RSS+
Sbjct:    7 PMDPAMDSSFMDGLLLEGCWLETT-DASEFLNFSPSTSVAPFDPSSFMWSPTQ--DTSNSLSQMYGQDCP-----ERSSLEDQNQGRDLSTFN----------RRWWIGP---SGHHGFSVMERLVQAVTHIKDFTSERGSLIQLWVPVDRGGKR-VLTTKEQPFSHDPMCQRLAHYREISENYQFSTEQEDSDSSSRDLV-GLPGRVFLGKVPEWTPDVRFFKNEEYPRVQHAQDCDVRGTLAIPVFEQGSQICLGVIEVVMTTQMVKLSPDLESICRALQAVDLRSTEIPIPPSLKGPDFSYQAALPEIRNLLRCACETHKLPLAQTWVSCLKQSKTGCRHNDENYIHCVSTIDDACYVGDPTVREFHEACSEHHLLKGQGVVGEAFLTNGPCFSSDVSSYKKSEYPLSHHATMFGLHGTVAIRLRCIHTGSVDFVLEFFLPKNCRDIEEQRKMLNALSTIMAHVPRSLRTVTQKELEEEGDSMVSEVIE-------KGVTLPKIEN---TTEVHQSISTPQNVGLVFDGGTTEMGEL----GSEYGKGVSVN-ENNTFSSASGFNRVTEKKRTKAEKNITLDVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGIQRWPSRKIKKVGHSLQKIQRVIDSVEGVSGHHLPIGSFYASF-----PNLAASPEASSLQQQSKITTFLSYSHSPPAKSPGSSC------------------------SHSSS-CSSETQVIKEDPTD--------------------KTRLVSRS-FKETQTTHL------------SPSSQEDDFLRVKVSYEEEKIRFKMRNSHRLKDLLWEIAKRFSIEDVSRYDLKYLDEDNEWVLLRCDDDVEECVDVCRSFPGQTIKLLLQLSSSYLPERSSV 803          

Query:   58 ENSMDFDYVSELLLDGCWLEASADGSDFL------LQSSPFSNPLFDPSFTWP-------SLDNID--------PPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRH---SSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNL-SANEVMDLADSGFASGATWSELQ----------------------HRRMAASLDGDF--------------FFNETMGG------KFSEQTQQQENLILKGDTE-SGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLS--GTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSS 2682
            +++MD D++ ELL DGCWLE + DG          +  S   N   + S+ +        S D+I         PP      K +D S     +  +++     S+ +  +F     EG   R+WI P  + GP  S + E+L++A++ + +  ++KD LIQIW+P+ + + + FLT ++ P     +  +L RYR++SV Y F A+E DSK+ V GLPGRV+  K+PEWTPDVRFFRS+EYPR+  A++CD+ G+LA+PVFE+GS TCLGV+E+V TTQ+ NY  EL+ +CKALE V+LRSSR     S + ++  +  Y  ALPE+ E L   C ++ LPLA TW PC +QGK G RHSD+N+  C+S V+ AC + D   R F EAC EHHLL+G+G+ G AF   +  F  ++T+ SK +YPL+HHA++ GL AA+A+ L++ +++S ++VLEFF P  C D+  Q+ ML SLS  +Q+  R+L +  +KELE   +    E +  A++   +  T  +++                       +    SL  ++              + N  +G         +EQ Q+  N  L+ D + S    S  V   LL S    EKRR K +KTI L+VLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQLVIDSVQG   + Q+DSFY+   +L+SP++S  GTS  +   Q +N VS           P  +                       Q  +T   ++    L+ E++   +LKR RSE  L ++ QD  K+  + R+ SH+T  EHP+ E    L +   +  +   A +VK T+G+ K RF +  TW + ++  EI RRFN+ +++ FD+KYLDDD EWVLLTC+ADLEECID+ +SS+  TIK+ +  +S
Sbjct:   23 DSAMDMDFMDELLFDGCWLETT-DGKSLKQTMGQQVSDSTTMNDNNNNSYLYGYQYAENLSQDHISNEETGRKFPPIPPGFLKIEDLSNQVPFDQSAVM-----SSAQAEKFLLEESEGG-RRYWIAPRTSQGPSSS-VKERLVQAIEGLNEEVQDKDFLIQIWLPIQQ-EGKNFLTTSEQPHFFNPKYSSLKRYRDVSVAYNFLADE-DSKESV-GLPGRVFLKKLPEWTPDVRFFRSEEYPRIKEAEQCDVRGSLALPVFERGSGTCLGVVEIVTTTQKMNYRPELDNICKALESVNLRSSRSLNPPSREFLQVYNEFYYAALPEVSEFLTLVCRVYDLPLALTWAPCARQGKVGSRHSDENFSECVSTVDDACIVPDHQSRHFLEACSEHHLLQGEGIVGKAFNATKLFFVPEVTTFSKTNYPLAHHAKISGLHAALAVPLKNKFNSSVEFVLEFFFPKACLDTEAQQDMLKSLSATLQQDFRSLNLFIDKELELEVVFPVREEVVFAENPLINAGTGEDMKPLPLEEISQEDSSWISHMIKANEKGKGVSLSWEYQKEEPKEEFMLTSGWDNNQIGSGHNNFLSEAEQFQKVTNSGLRIDMDPSFESASFGVGQTLLGSRRPGEKRRTKTEKTIGLEVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGITRWPSRKIKKVGHSLKKLQLVIDSVQGVQGSIQLDSFYTSFPELSSPHMSGTGTSFKNPNAQTENGVSAQGTAAAPKSPPSSS-------CSHSSGSSTCCSTGANQSTNTGTTSNTVTTLMAENA-SAILKRARSEVRLHTMNQDETKS--LSRTLSHKTFSEHPLFENPPRLPENSSRKLKAGGASKVKATFGEAKVRFTLLPTWGFRELQHEIARRFNIDNIAPFDLKYLDDDKEWVLLTCEADLEECIDIYRSSQSRTIKISVHEAS 946          

Query:   58 ENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRH---SSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRV-ITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGK----------------------------------FSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSS 2682
            + +MD D++ ELL DGCWLE +   S    + SP ++   + +  +         DN    +++   +  + E   +   + G +                 WWI P+ + GP  S + E+L++A+  + +  ++KD L+QIWVP+ + + + FLT    P        +LA YR +S  Y F A+E   KD V GLPGRV+  K PEWTPDVRFFR DEYPR+  AQ+CD+ G+LA+PVFE+GS TCLGV+E+V TTQ+ NY  ELE +CKALE VDLRSS +    S + ++     Y  ALPEI++ L + C  +  PLA +W PC +QGK G RHSD+N+  C+S ++ AC + D   + F EAC EHHLL+G+G+ G AF   +  F  ++ + SK +YPL+HHA++ GL AA+A+ L+S  S   ++VLEFF P  C D+  Q++ML SL + +Q+  R+  + I + ELE   L   E M  +++      T   L   +M  S            GK                                   +EQ QQ     L+ D     E + +  GN+LSS    EK+R K +KTI L+VLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQLV+DSVQGA  + Q+DSFY+   +L SPN+S      +L   +    LN Q D   ++ E+                       +    +NN  +  + LV ED+ D VLKR  SEA+L ++ Q+  K   + R+QSH+T  E  + +    L  +   + +   A +VK T+G+ + RF +  +W + ++ QEI RRFN+ D+S FD+KYLDDD EWVLLTC+ADL ECID+ + ++  TIK+ L  +S
Sbjct:   27 DTAMDLDFMDELLFDGCWLETTDSKSLKQTEQSPSASTAMNDNSPFLCFGENPSQDNFSNEETE--RMFPQAEKFLLEEAEVGKS-----------------WWIAPSASEGPSSS-VKERLLQAISGLNEAVQDKDFLVQIWVPIQQ-EGKSFLTTWAQPHLFNQEYSSLAEYRHVSETYNFPADE-GMKDFV-GLPGRVFLQKFPEWTPDVRFFRRDEYPRIKEAQKCDVRGSLALPVFERGSGTCLGVVEIVTTTQKMNYRQELEKMCKALEAVDLRSSSNLNTPSSEFLQVYSDFYCAALPEIKDFLATICRSYDFPLALSWAPCARQGKVGSRHSDENFSECVSTIDSACSVPDEQSKSFWEACSEHHLLQGEGIVGKAFEATKLFFVPEVATFSKTNYPLAHHAKISGLHAALAVPLKS-KSGLVEFVLEFFFPKACLDTEAQQEMLKSLCVTLQQDFRSSNLFIKDLELEV-VLPVRETMLFSENLLCGAETVESLTEIQMQESSWIAHMIKANEKGKDVSLSWEYQKEDPKELSSGRENSQLDPVPNNVPLEAEQLQQASTPGLRVDIGPSTESASTGGGNMLSSRRPGEKKRAKTEKTIGLEVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGIMRWPSRKIKKVGHSLKKLQLVMDSVQGAQGSIQLDSFYTSFPELNSPNMSSNG--PSLKSNEQPSHLNAQTDNGIMAEEN--------------PRSPSSSCSKSSGSSNNNENTGNILVAEDA-DAVLKRAHSEAQLHNVNQEETKC--LARTQSHKTFKEPLVLDNSSPLTGSSNTSLRARGAIKVKATFGEARIRFTLLPSWGFAELKQEIARRFNIDDISWFDLKYLDDDKEWVLLTCEADLVECIDIYRLTQTHTIKISLNEAS 895          

Query:  364 WWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNK------DMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNN--------------LSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGK----------FSEQTQQQENLIL----------KGDTESG---------RECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPD-PD---------SLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRI-RSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPS 2679
            W     P        + E+L RAL+ I    +++      ++L+Q+WVP   GD R  LT    PF L+ R+  LA YR +S++YQFSA+E    DL  GLPGRV+  +VPEWTPDVR+F ++EYPRV HAQ  DI G++A+PVFE  SR CLGV+E+VMTTQ+ NYSAE+E +C AL+ VDLRSS  SS    K  D SY   +PEI +VLR+ C+ H LPLAQTWIPCI Q K G RHSD++Y HC+S V+ ACY+ D SV  FH+AC EHHL +G+GV G AF TN+PCFS DIT+ SK  YPLSHHA+LFGLRAAVAI+LRS+ + S D+VLEFFLP+ C ++ EQ+ ML SLS  IQ+VC  LRV+  KEL  +                S +E +D   SG       + L+     +S        +  GGK          FS+Q  +  ++             G   SG         +E + S + +  +S    EKRR K +KT++LQ LR++FAGSLK+AAKN+GVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQ+VIDSV G   T Q+ S Y    +      S   L   ++   ++ +   +P  PD           S  ++                      +Q       A  ++  + E+    ++K    +EAEL+  +++  +  ++ RSQS   L EH   E   ++ K       + D+ ++K  YG+E+  FR+  +W ++ + +EI +RF +S  +  D+KYLDD+ EWVLLTCDADL ECIDV +SS   T+++ + PS
Sbjct:  110 WTFQTAPQEVAVEPTVKERLRRALERIASQSQSQAQRGDGELLVQVWVPTRIGD-RQVLTTCGQPFWLDRRNQRLANYRTVSMKYQFSADESARADL--GLPGRVFVGRVPEWTPDVRYFSTEEYPRVQHAQYFDIRGSVALPVFEPRSRACLGVVELVMTTQKVNYSAEIENICNALKEVDLRSSDVSSDPRSKVVDASYRAIIPEIMDVLRAVCDTHNLPLAQTWIPCICQAKRGSRHSDESYKHCVSTVDEACYVRDCSVLGFHQACSEHHLFRGEGVVGRAFGTNEPCFSPDITTYSKTQYPLSHHAKLFGLRAAVAIQLRSVKTGSLDFVLEFFLPMKCINTEEQRAMLNSLSNTIQQVCYTLRVVKPKELVNDGPFEISQPTRPEFYAKSVHEDLDELCSGINVPGRTTSLEASEEVSSWIASLVDAQNKGGKGEIDVDLPFGFSKQDDEGFSVTAGWHTSPVMAPDGSMFSGFKRHEDYDVKENTCSSDPSNSNSDKAVEKRRTKTEKTVSLQDLRKHFAGSLKEAAKNLGVCPTTLKRICRQHGINRWPSRKIKKVGHSLKKLQMVIDSVHGPEGTVQLSSLY---ENFTKTTWSERELQGDVHFPASEQNFQLEPSVPDRPCEGRFTSHTSGSNSISPSCSQSSNSSLGCSSVPKTQQQHGSAPQLAVKEEISMDENQCSTLIKSASHAEAELQMFVEE--RPTMLFRSQSQVLLSEHKPIENMSNVQKA------RSDSLKIKAIYGEERCIFRLQPSWGFQRLKEEIVKRFGISQDTHVDLKYLDDESEWVLLTCDADLLECIDVYKSSSNQTVRILVNPS 927          

Query:  364 WWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPV-NRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQG--------KDGCRHSDDNYVH--CISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRM--AASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLV----------GEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLE 2706
            W I P  N     + I  K+ +AL++ K+    + +L Q+W PV NRG  R  LT +  PF L   S  L +YR +S+ Y FS + E   +L  GLPGRV+R K+PEWTP+V+++ S E+ R+ HA   ++ GTLA+PVFE   + C+GV+E++MT+ + NY+ E+E VCKALE V+L++S   + +  +  +   + AL EI E+L   CE +KLPLAQTW+PC  +         K  C   D + +   C+S  + A Y+ D+ V  F +AC EHHL KGQGVAG AF +   CF  D+T   K DYPL H+AR+F L +  A+ L+S Y+  D+YVLEFFLP    D  EQ  +L SL   +++   +L+V++  EL +NN+S  EV++ ++ G      +S+L+  R+   A +  D+        K S  +   EN  +    E  +      E     +V   E++R K +KTI+L+VL+QYFAGSLKDAAK++GVC TT+KRICRQHGI RWPSRKI KV  SL +L+ VIDSVQGA  +  + S            LS       +  ID Q++ N    P S SP                              T+  +   +P+            E S  V L     +++  S    N  A++  +  +  T+ +H +            KA+ +ED  R K++          P++    ++ Q++ +R  + + + F++KYLDDD EWV ++CDADL EC+D   +++ +T++L +   +    SS E
Sbjct:   90 WGIMPLENPDSYCA-IKAKMTQALRYFKESTGQQHVLAQVWAPVKNRG--RYVLTTSGQPFVLGPNSNGLNQYRMVSLTYMFSLDGERDGEL--GLPGRVFRKKLPEWTPNVQYYSSKEFSRLGHALHYNVQGTLALPVFEPSRQLCVGVVELIMTSPKINYAPEVEKVCKALEAVNLKTSEILNHETTQICNEGRQNALAEILEILTVVCETYKLPLAQTWVPCRHRSVLAFGGGFKKSCSSFDGSCMGKVCMSTSDLAVYVVDAHVWGFRDACAEHHLQKGQGVAGRAFQSGNLCFCRDVTRFCKTDYPLVHYARMFKLTSCFAVCLKSTYTGDDEYVLEFFLPPAITDKSEQDCLLGSLLQTMKQHYSSLKVVSETELCENNMSL-EVVEASEDGM----VYSKLEPIRIHHPAQISKDYLELNAPEQKVSLNSDFMENNEVDDGVERFQTLDPIPEA---KTVKKSERKRGKTEKTISLEVLQQYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKVNRSLTRLKHVIDSVQGADGSLNLTS------------LSPRPWPHQIPPIDIQLAKNC--PPTSTSP---------LSNLQDVKIENRDAEDSAGSSTSRASCKVNPICETRFRLPTHNQEPSRQVAL----DDSDSSSKNMTNFWAHLTCQDTASPTILQHKLVSI---------KATYREDIIRFKIS----------PESVSITELKQQVAKRLKL-ETAAFELKYLDDDREWVSVSCDADLSECLDT-SAAKANTLRLSVHDVTFNFGSSCE 832          

Query:  415 EKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQG--------KDGCRHSDDNYVH--CISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQH-RRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTES-----GRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSL-ISTLNQIDNQVSLNTQPDPDS 2100
            E+L +AL++ K+   ++ +L+Q+W PV  GD R  LT +  PF L+ +S+ L +YR +S+ Y FS + E++ +L  GLPGRVY+ KVPEWTP+V+++ S EYPR++HA   ++HGT+A+PVF+   + C+ V+E++MT+++ NY+ E++ VCKALE V+L+S+      NV+  +   ++AL EI E+L   CE HKLPLAQTW+PC  +         K  C   D + +   C+S  + A ++ D+ +  F +AC+EHHL KGQGV+G AF+  +PCFS DI+   K++YPL H+AR+FGL    AI L+S+Y+  DDY+LEFFLP +C +  +Q  +L S+   +++  R L+V+ N +  +  L  + V+ +      +   +   +   R +   +G    +E            + +L+   ++++     GR        +L  S    E+RR KA+KTI+L VL+QYF+GSLK+AAK++GVC TT+KRICRQHGI RWPSRKI KV  SL KL+ VI+SVQG+ + F + S    L     P+    +L  ++ N++    +L  + D DS
Sbjct:  137 ERLTQALRYFKE-STDQHLLVQVWAPVKSGD-RYVLTTSGQPFVLDQQSIGLLQYRAVSMMYMFSVDGENAGEL--GLPGRVYKQKVPEWTPNVQYYSSTEYPRLNHAISYNVHGTVALPVFDPSVQNCIAVVELIMTSKKINYAGEVDKVCKALEAVNLKSTEILDHPNVQICNEGRQSALVEILEILTVVCEEHKLPLAQTWVPCKYRSVLAHGGGVKKSCLSFDGSCMGEVCMSTSDVAFHVIDAHMWGFRDACVEHHLQKGQGVSGKAFIYRRPCFSKDISQFCKLEYPLVHYARMFGLAGCFAICLQSMYTGDDDYILEFFLPPNCRNEDDQNALLESILARMKKCLRTLKVVGNGDTNEVCLQISNVLIIETEDLKTNVHFENSEGCFRESPESNGSQRVHEVDNDGNKVSIMSERHLLADDNSQNNGASVGRPNGSGASDSLHKSNKPPERRRGKAEKTISLDVLQQYFSGSLKNAAKSLGVCPTTMKRICRQHGISRWPSRKINKVNRSLSKLKQVIESVQGSDAAFNLTSITGPLPIPVGPSSDSQNLEKASPNKVAELSNLAVEGDRDS 711          

Query: 2437 VKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEI 2649
            +K ++ ++  RFR P +     +  E+ +R  + D+  FDIKYLDDD EWV L C+ADLEEC+++  S  I
Sbjct:  850 IKASFKEDIVRFRFPCSGSVTALKDEVAKRLRM-DVGMFDIKYLDDDHEWVKLACNADLEECMEISGSHVI 919          

Query:  409 IVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQG---------KDGCRHSDDNYVH--CISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKEL--EKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSF----------YSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPE 2112
            I E++ +AL++ K+    + +L Q+W PV R + R  LT    PF L      L +YR IS+ Y FS + E   +L  GLPGRV+R K+PEWTP+V+++ S E+ R+DHA   ++ GTLA+PVF    ++C+GV+E++MT+++ +Y+ E++ VCKALE V+L+SS     Q  +  + S + AL EI EVL   CE H LPLAQTW+PC Q G         K  C   D + +   C+S  + ACY+ D+ V  F +AC+EHHL KGQGVAG AF+    CF  DIT   K  YPL H+A +F L    AI L+S Y+  D Y+LEFFLP    D  EQ  +L S+ + ++   ++LRV +  +   + + LS   +  L D         S+++  R+  S    F  N T       +T      +++       + +++    ++      EK+R K +KTI+L VL+QYF GSLKDAAK++GVC TT+KRICRQHGI RWPSRKIKKV  S+ KL+ VI+SVQG      + S            +    L SPN S    +   N   N  S +  P+  + SPE
Sbjct:  147 IKERMTQALRYFKE-STEQHVLAQVWAPV-RKNGRDLLTTLGQPFVLNPNGNGLNQYRMISLTYMFSVDSESDVEL--GLPGRVFRQKLPEWTPNVQYYSSKEFSRLDHALHYNVRGTLALPVFNPSGQSCIGVVELIMTSEKIHYAPEVDKVCKALEAVNLKSSEILDHQTTQICNESRQNALAEILEVLTVVCETHNLPLAQTWVPC-QHGSVLANGGGLKKNCTSFDGSCMGQICMSTTDMACYVVDAHVWGFRDACLEHHLQKGQGVAGRAFLNGGSCFCRDITKFCKTQYPLVHYALMFKLTTCFAISLQSSYTGDDSYILEFFLPSSITDDQEQDLLLGSILVTMKEHFQSLRVASGVDFGEDDDKLSFEIIQALPDK-----KVHSKIESIRVPFS---GFKSNAT-------ETMLIPQPVVQSSDPVNEKINVATVNGVVKEKKKTEKKRGKTEKTISLDVLQQYFTGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKIKKVNRSITKLKRVIESVQGTDGGLDLTSMAVSSIPWTHGQTSAQPLNSPNGSKPPELPNTNNSPNHWSSDHSPNEPNGSPE 717          

Query: 2437 VKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLE 2706
            +K +Y D+  RFR+       ++  E+ +R  V D   FDIKYLDDD EWVL+ CDADL+EC+++ +SS    ++L +   +  + SS E
Sbjct:  866 IKASYKDDIIRFRISSGSGIMELKDEVAKRLKV-DAGTFDIKYLDDDNEWVLIACDADLQECLEIPRSSRTKIVRLLVHDVTTNLGSSCE 954          

Query:  415 EKLIRALK-WIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCI--QQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVI-----TNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLIL--KGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIG-------------VCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQV----SLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNN----FASNKDPLVGEDSVDVVLKRIRSEAELK-----------SLIQDNNKANVMPRSQSHET------LGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSS 2700
            EK+++AL  +++     + +L Q+W P+  GD    L+  D  + L+ R    ++YRE+S R+ F+AE         GLPGRV+   VPEWT +V ++++DEY R+ HA + ++ G++A+P+ E    +C  V+E+V + ++ N+  E+++VC+AL+ V+LR++     Q + +  R    AL EIQ+VLR+ C  HKLPLA  WIPC   Q  +   + S +N + CI   E ACY+ D  +  F  AC+EH L + +G+ G AF++NQP FS+D+ +    +YP+  HAR +GL AAVAI+LRS Y+  DDY+LE FLPV    S EQ+ +L SLS  +QR+CR LR +     T KE  K    ++++     S F    +    Q      SLD +F    +M   FS  +  +EN I   +G  E             +S     EK++   +K ++L  L+Q+F+GSLKDAAK++G              C TTLKRICRQHGI RWPSRKI KV  SL+K+Q V+DSVQG     + DS   +      P +        L+ +DN      S    PD  S   ++A                        + + +     + + +  L G + +  V     S  E+            S+++ N   +      S+ +           + +++Q        +        VK +Y ++  RF+   +     + +E+G+RF + D S F +KYLDD+ EWV+L  D+DL+EC+++       ++K  ++  S  + SS
Sbjct:  165 EKMLKALSLFMESSGSGEGILAQVWTPIKTGDQY-LLSTCDQAYLLDPR---FSQYREVSRRFTFAAEANQCS--FPGLPGRVFISGVPEWTSNVMYYKTDEYLRMKHAIDNEVRGSIAIPILEASGTSCCAVMELVTSKEKPNFDMEMDSVCRALQAVNLRTAAIPRPQYLSSSQRD---ALAEIQDVLRTVCHAHKLPLALAWIPCRKDQSIRVSGQKSGENCILCIE--ETACYVNDMEMEGFVHACLEHCLREKEGIVGKAFISNQPFFSSDVKAYDISEYPIVQHARKYGLNAAVAIKLRSTYTGEDDYILELFLPVSMKGSLEQQLLLDSLSGTMQRICRTLRTVSEVGSTKKEGTKPGFRSSDM-----SNFPQTTSSENFQ----TISLDSEFNSTRSM---FSGMSSDKENSITVSQGTLEQD-----------VSKARTPEKKKSTTEKNVSLSALQQHFSGSLKDAAKSLGGETSAYFQAWVYFFCPTTLKRICRQHGIMRWPSRKINKVNRSLRKIQTVLDSVQGVEGGLKFDSATGEFI-AVRPFIQEIDTQKGLSSLDNDAHARRSQEDMPDDTSFKLQEAKSVDNAIKLEEDTTMNQARPGSFMEVNASGQPWAWMAKESGLNGSEGIKSVCN--LSSVEISDGMDPTIRCSGSIVEPNQSMSCSISDSSNGSGAVLRGSSSTSMEDWNQMRTHNSNSSESGSTTLIVKASYREDTVRFKFEPSVGCPQLYKEVGKRFKLQDGS-FQLKYLDDEEEWVMLVTDSDLQECLEILHGMGKHSVKFLVRDLSAPLGSS 936          

Query:  415 EKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQG-------KDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDF---FFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPD---SLSP--------------EDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAEL------------KSLIQDNNKANVMPRSQSHET----LGEHPIT-EYHQSLLKTDRKASQKEDAH--RVKVTYGDEKSRFRM-PKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSN 2685
            EK+++AL    +F   + +L Q W P+  GD    L+  D  + L++R   L+ YRE S R+ FSAE         GLPGRV+   VPEWT +V ++++ EY R+ HA + ++ G++A+PV E    +C  V+E+V   ++ N+  E+ +VC+AL+ V+L++S     Q + +  +    AL EI++VLR+ C  H+LPLA  WIPC           K   ++S +  + CI   E +CY+ D  +  F  AC+EH+L +GQG+ G A ++N+P FS+D+ +    +YPL  HAR FGL AAVA +LRS ++  +DY+LEFFLPV    S EQ+ +L SLS  +QR+CR L+ +++ E              +  G   G+   E+ +   A    G F   F +  +    S  +    N   K +  +G + +L  E   +S     EK++   +K ++L VL+QYF+GSLKDAAK++GVC TTLKRICRQHGI RWPSRKI KV  SL+K+Q V+DSVQG     + DS   +      P +       +L+  D      +Q D D   S+ P              ED                          +  +     +   V +D  D+ ++R  S   L               ++ N+  +      S+ +    LG    + E + + ++T   + +   +    VK TY ++  RF++ P       + +E+ +RF + +   F +KYLDD+ EWV+L  D+DL EC ++       T+K  ++   N
Sbjct:  108 EKMLKALSLFMEFS-GEGILAQFWTPIKTGDQY-MLSTCDQAYLLDSR---LSGYREASRRFTFSAEANQCS--YPGLPGRVFISGVPEWTSNVMYYKTAEYLRMKHALDNEVRGSIAIPVLEASGSSCCAVLELVTCREKPNFDVEMNSVCRALQAVNLQTSTIPRRQYLSSNQKE---ALAEIRDVLRAVCYAHRLPLALAWIPCSYSKGANDELVKVYGKNSKECSLLCIE--ETSCYVNDMEMEGFVNACLEHYLREGQGIVGKALISNKPSFSSDVKTFDICEYPLVQHARKFGLNAAVATKLRSTFTGDNDYILEFFLPVSMKGSSEQQLLLDSLSGTMQRLCRTLKTVSDAE--------------SIDGTEFGSRSVEMTNLPQATVSVGSFHTTFLDTDVNSTRSTFSNISSN---KRNEMAGSQGTLQQE---ISGARRLEKKKSSTEKNVSLNVLQQYFSGSLKDAAKSLGVCPTTLKRICRQHGIMRWPSRKINKVNRSLRKIQTVLDSVQGVEGGLKFDSVTGEFV-AVGPFIQEFGTQKSLSSHDEDALARSQGDMDEDVSVEPLEVKSHDGGGVKLEEDVETNHQAGPGSLKKPWTWISKQSGLIYSDDTDIGKRSEEVNKDKEDLCVRRCLSSVALAGDGMNTRIERGNGTVEPNHSISSSMSDSSNSSGAVLLGSSSASLEQNWNQIRTHNNSGESGSSSTLTVKATYREDTVRFKLDPYVVGCSQLYREVAKRFKLQE-GAFQLKYLDDEEEWVMLVTDSDLHECFEILNGMRKHTVKFLVRDIPN 877          

Query:    4 EDGALTSSTTMMEAPQPD---ENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRS---IVNVDGGSNQKEYRFETYSGEGF---FSRWWIGPT----PNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIR---EKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXE-QQHHTNNFASNKDP-LVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLEFR 2712
            + G ++S+ TMMEAP PD     SMDFDY+ EL LDGCW+EASADGSDFLLQS  FSN LFDPSF+WP+L+        + ++SQ A+ G++QES +   +  V GG   ++++ ET+S EG      RWW  PT    P+ GPG S I+EKLIRAL WIKD++RNKDMLIQIWVPV++ + RP L A+DL FSLE++SLNLA+YREISV Y+FSAEE DSK+L  GLPGRV+RDKVPEWTPDVRFF+ DEYPRVDHAQE D+ GTLAVP+FEQGS+TCLGVIEVVMTTQQ NY  ELE+VCKALE VDLRSS+  S+QNVKA +RSYE ALPEI EVLRSACEMHKLPLAQTW+PC+QQGK+GCRHS+DNY+ CISPVE+ACY+GD S+R FHEAC EHHLLKG+GVAGGAFMTNQPCFS DITSLSK DYP+SHHARLFGLRAAVAIRLRSIY+++DD+VLEFFLPVDCND  EQ+KMLTSLS IIQRVCR+LRVI  KELE+ NLS NEV+ LADSGF      SE Q + M ASLD +   +ETMG KFSE  QQQE+ ILKG+ +  RECS SVEGN LSS G     E+RR KA+KTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGAS  FQI+SFYS   DLASPNLSGT   STLNQ DN  S +TQP+  SLSPE A                      E QQ HT N AS+KDP  VGE S DVVLK IR+EA+LKSL QD  +A ++PRS S ETLGEHP T+Y   LLKT   +S K D+HRVKVTYGDEK+RFRM K W YED++QEIGR+FNVSDMSKFD+KYLDDDCEW+LLTCDADLEECIDVCQSSE  TIKL LQPSS+ +RSSLEFR
Sbjct:    4 DGGVISSAATMMEAPPPDGTTTTSMDFDYMGELFLDGCWMEASADGSDFLLQSPSFSNTLFDPSFSWPALET-------NHNESQVAAFGSQQESHNNNMVSVVAGGDYSQQFQSETHSVEGASEGIRRWWFAPTHTPTPSPGPGPS-IMEKLIRALMWIKDYNRNKDMLIQIWVPVHK-EGRPILAADDLLFSLESKSLNLAKYREISVTYKFSAEESDSKELAWGLPGRVFRDKVPEWTPDVRFFKIDEYPRVDHAQEYDVRGTLAVPIFEQGSKTCLGVIEVVMTTQQINYGPELESVCKALEAVDLRSSKQLSIQNVKACNRSYEAALPEIHEVLRSACEMHKLPLAQTWVPCVQQGKEGCRHSEDNYLLCISPVEHACYVGDPSIRSFHEACTEHHLLKGEGVAGGAFMTNQPCFSDDITSLSKKDYPMSHHARLFGLRAAVAIRLRSIYNSTDDFVLEFFLPVDCNDIEEQRKMLTSLSNIIQRVCRSLRVIREKELEEANLSVNEVIALADSGFTRDEICSEPQQKGMVASLDTEEKSSETMGRKFSEPRQQQESPILKGNLDCVRECSTSVEGN-LSSPGTSKTGERRRVKAEKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASGAFQINSFYSNFPDLASPNLSGTGFFSTLNQSDNPNSTSTQPEHGSLSPEGASKSPSSSSSQSSISSHSCSSMSELQQQHTTNIASDKDPATVGEYSADVVLKLIRNEAKLKSLSQD--RAKLLPRSLSQETLGEHPKTQYQLPLLKT---SSSKVDSHRVKVTYGDEKTRFRMLKNWVYEDLLQEIGRKFNVSDMSKFDVKYLDDDCEWILLTCDADLEECIDVCQSSESGTIKLSLQPSSHSVRSSLEFR 909          

Query:    4 EDGALTSSTTMMEAPQPD-----ENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRS--IVNVDGGSNQKEYRFETYSGEGFFS---RWWIGPTPNSGPG-GSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIR---EKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXE-QQHHTNNFASNK-DPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLEFR 2712
            + G  +S+ TMMEAP PD       SMDFDY+ E  LDGCWLEASAD SDFLLQS  FSNPLFDPS +WP+L+        + +KSQDA+ GT+QES +  +  V GG   ++++ ET+S EG      RWW  P+P   PG G  I+EKLIRAL WIKD++RNKDMLIQIWVP+++ + RP L A+DL FSLE++SLNLA+YREISV Y+FSAEE DSK+L  GLPGRV+R KVPEWTPDVRFFRSDEYPRVDHAQE D+ GT+AVP+FEQGS+TCLGVIEVVMTTQQ NY  ELE+VCKALE VDLRSS+  S+QNVKA +R+YE ALPEI EVLRSACEMH+LPLAQTW+PC+QQGK+GCRHS+DNY+ CISPVE+ACY+GD S+R FHEAC EHHLLKG+GVAGGAFMTNQPCFS DITSLSK DYPLSH+ARLFGL AAVAIRLRSIY+++DD+VLEFFLPVDCNDS EQ+KMLT+LS+IIQRVCR+LRVI +KELE+ NLS +EV+ LADSGFA  A +SE Q++ M ASLD +   +ETMG KFS+  QQQE+ ILKG+ +  +ECS SVEGN LSS+G     E+RR KA+KTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVI+SVQGAS  FQI SFYS   DLASPNLSGT   STLNQ D   S +TQPD  SLSPE A                      E QQH T N A NK    V EDS  VVLKRI SEAELKSL QD  +A ++PRSQS ETLGEHP T+Y Q LLKT   +S K D+HRVKV YGDEK+RFRMPK+W YED++QEI RRFNVSDMSKFD+KYLDDDCEWVLLTCDADLEECIDVCQSSE  TIKL LQPSS+ +RSSLEFR
Sbjct:    3 DSGVTSSAATMMEAPPPDGTTTTATSMDFDYMGEFFLDGCWLEASADVSDFLLQSPSFSNPLFDPSLSWPALET-------NHNKSQDAAFGTQQESHNNIVSVVAGGGYSQQFQSETHSVEGVSEGVRRWWFAPSPIPSPGPGPSIMEKLIRALMWIKDYNRNKDMLIQIWVPIHK-EGRPILAADDLLFSLESKSLNLAKYREISVTYEFSAEESDSKELARGLPGRVFRYKVPEWTPDVRFFRSDEYPRVDHAQEYDVRGTVAVPIFEQGSKTCLGVIEVVMTTQQINYGPELESVCKALEAVDLRSSKQLSIQNVKACNRTYEAALPEIYEVLRSACEMHRLPLAQTWVPCVQQGKEGCRHSEDNYLLCISPVEHACYVGDPSIRSFHEACTEHHLLKGEGVAGGAFMTNQPCFSDDITSLSKKDYPLSHYARLFGLHAAVAIRLRSIYNSTDDFVLEFFLPVDCNDSEEQRKMLTALSIIIQRVCRSLRVIRDKELEEANLSVDEVIALADSGFARNAIFSEPQYKGMVASLDAEEKSSETMGRKFSDLRQQQESPILKGNLDCVKECSTSVEGN-LSSLGTNKTGERRRAKAEKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVINSVQGASGAFQIGSFYSNFPDLASPNLSGTGFFSTLNQSDYPNSTSTQPDHGSLSPEGASKSPSSSCSQSSISSHSCSSMSELQQHRTANGAGNKVSTTVSEDSAGVVLKRISSEAELKSLSQD--RAKLLPRSQSQETLGEHPKTQYQQPLLKT---SSSKVDSHRVKVAYGDEKTRFRMPKSWGYEDLLQEIARRFNVSDMSKFDVKYLDDDCEWVLLTCDADLEECIDVCQSSESGTIKLSLQPSSHSMRSSLEFR 907          

Query:    4 EDGALTSSTTMMEAPQPD---ENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRS---IVNVDGGSNQKEYRFETYSGEGF---FSRWWIGPT----PNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVK-ARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIR---EKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXE-QQHHTNNFASNKDP-LVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLEFR 2712
            + G ++S+ TMMEAP PD     SMDFDY+ EL LDGCW+EASADGSDFLLQS  FSN LFDPSF+WP+L+        + ++SQ A+ G++QES +   +  V GG   ++++ ET+S EG      RWW  PT    P+ GPG S I+EKLIRAL WIKD++RNKDMLIQIWVPV++ + RP L A+DL FSLE++SLNLA+YREISV Y+FSAEE DSK+L  GLPGRV+RDKVPEWTPDVRFF+ DEYPRVDHAQE D+ GTLAVP+FEQGS+TCLGVIEVVMTTQQ NY  ELE+VCKALE VDLRSS+  S+QNVK A +RSYE ALPEI EVLRSACEMHKLPLAQTW+PC+QQGK+GCRHS+DNY+ CISPVE+ACY+GD S+R FHEAC EHHLLKG+GVAGGAFMTNQPCFS DITSLSK DYP+SHHARLFGLRAAVAIRLRSIY+++DD+VLEFFLPVDCND  EQ+KMLTSLS IIQRVCR+LRVI  KELE+ NLS NEV+ LADSGF      SE Q + M ASLD +   +ETMG KFSE  QQQE+ ILKG+ +  RECS SVEGN LSS G     E+RR KA+KTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGAS  FQI+SFYS   DLASPNLSGT   STLNQ DN  S +TQP+  SLSPE A                      E QQ HT N AS+KDP  VGE S DVVLK IR+EA+LKSL QD  +A ++PRS S ETLGEHP T+Y   LLKT   +S K D+HRVKVTYGDEK+RFRM K W YED++QEIGR+FNVSDMSKFD+KYLDDDCEW+LLTCDADLEECIDVCQSSE  TIKL LQPSS+ +RSSLEFR
Sbjct:    4 DGGVISSAATMMEAPPPDGTTTTSMDFDYMGELFLDGCWMEASADGSDFLLQSPSFSNTLFDPSFSWPALET-------NHNESQVAAFGSQQESHNNNMVSVVAGGDYSQQFQSETHSVEGASEGIRRWWFAPTHTPTPSPGPGPS-IMEKLIRALMWIKDYNRNKDMLIQIWVPVHK-EGRPILAADDLLFSLESKSLNLAKYREISVTYKFSAEESDSKELAWGLPGRVFRDKVPEWTPDVRFFKIDEYPRVDHAQEYDVRGTLAVPIFEQGSKTCLGVIEVVMTTQQINYGPELESVCKALEAVDLRSSKQLSIQNVKQACNRSYEAALPEIHEVLRSACEMHKLPLAQTWVPCVQQGKEGCRHSEDNYLLCISPVEHACYVGDPSIRSFHEACTEHHLLKGEGVAGGAFMTNQPCFSDDITSLSKKDYPMSHHARLFGLRAAVAIRLRSIYNSTDDFVLEFFLPVDCNDIEEQRKMLTSLSNIIQRVCRSLRVIREKELEEANLSVNEVIALADSGFTRDEICSEPQQKGMVASLDTEEKSSETMGRKFSEPRQQQESPILKGNLDCVRECSTSVEGN-LSSPGTSKTGERRRVKAEKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASGAFQINSFYSNFPDLASPNLSGTGFFSTLNQSDNPNSTSTQPEHGSLSPEGASKSPSSSSSQSSISSHSCSSMSELQQQHTTNIASDKDPATVGEYSADVVLKLIRNEAKLKSLSQD--RAKLLPRSLSQETLGEHPKTQYQLPLLKT---SSSKVDSHRVKVTYGDEKTRFRMLKNWVYEDLLQEIGRKFNVSDMSKFDVKYLDDDCEWILLTCDADLEECIDVCQSSESGTIKLSLQPSSHSVRSSLEFR 910          

Query:    4 EDGALTSSTTMMEAPQPD-----ENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRS--IVNVDGGSNQKEYRFETYSGEGFFS---RWWIGPTPNSGPG-GSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVK-ARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIR---EKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXE-QQHHTNNFASNK-DPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLEFR 2712
            + G  +S+ TMMEAP PD       SMDFDY+ E  LDGCWLEASAD SDFLLQS  FSNPLFDPS +WP+L+        + +KSQDA+ GT+QES +  +  V GG   ++++ ET+S EG      RWW  P+P   PG G  I+EKLIRAL WIKD++RNKDMLIQIWVP+++ + RP L A+DL FSLE++SLNLA+YREISV Y+FSAEE DSK+L  GLPGRV+R KVPEWTPDVRFFRSDEYPRVDHAQE D+ GT+AVP+FEQGS+TCLGVIEVVMTTQQ NY  ELE+VCKALE VDLRSS+  S+QNVK A +R+YE ALPEI EVLRSACEMH+LPLAQTW+PC+QQGK+GCRHS+DNY+ CISPVE+ACY+GD S+R FHEAC EHHLLKG+GVAGGAFMTNQPCFS DITSLSK DYPLSH+ARLFGL AAVAIRLRSIY+++DD+VLEFFLPVDCNDS EQ+KMLT+LS+IIQRVCR+LRVI +KELE+ NLS +EV+ LADSGFA  A +SE Q++ M ASLD +   +ETMG KFS+  QQQE+ ILKG+ +  +ECS SVEGN LSS+G     E+RR KA+KTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVI+SVQGAS  FQI SFYS   DLASPNLSGT   STLNQ D   S +TQPD  SLSPE A                      E QQH T N A NK    V EDS  VVLKRI SEAELKSL QD  +A ++PRSQS ETLGEHP T+Y Q LLKT   +S K D+HRVKV YGDEK+RFRMPK+W YED++QEI RRFNVSDMSKFD+KYLDDDCEWVLLTCDADLEECIDVCQSSE  TIKL LQPSS+ +RSSLEFR
Sbjct:    3 DSGVTSSAATMMEAPPPDGTTTTATSMDFDYMGEFFLDGCWLEASADVSDFLLQSPSFSNPLFDPSLSWPALET-------NHNKSQDAAFGTQQESHNNIVSVVAGGGYSQQFQSETHSVEGVSEGVRRWWFAPSPIPSPGPGPSIMEKLIRALMWIKDYNRNKDMLIQIWVPIHK-EGRPILAADDLLFSLESKSLNLAKYREISVTYEFSAEESDSKELARGLPGRVFRYKVPEWTPDVRFFRSDEYPRVDHAQEYDVRGTVAVPIFEQGSKTCLGVIEVVMTTQQINYGPELESVCKALEAVDLRSSKQLSIQNVKQACNRTYEAALPEIYEVLRSACEMHRLPLAQTWVPCVQQGKEGCRHSEDNYLLCISPVEHACYVGDPSIRSFHEACTEHHLLKGEGVAGGAFMTNQPCFSDDITSLSKKDYPLSHYARLFGLHAAVAIRLRSIYNSTDDFVLEFFLPVDCNDSEEQRKMLTALSIIIQRVCRSLRVIRDKELEEANLSVDEVIALADSGFARNAIFSEPQYKGMVASLDAEEKSSETMGRKFSDLRQQQESPILKGNLDCVKECSTSVEGN-LSSLGTNKTGERRRAKAEKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVINSVQGASGAFQIGSFYSNFPDLASPNLSGTGFFSTLNQSDYPNSTSTQPDHGSLSPEGASKSPSSSCSQSSISSHSCSSMSELQQHRTANGAGNKVSTTVSEDSAGVVLKRISSEAELKSLSQD--RAKLLPRSQSQETLGEHPKTQYQQPLLKT---SSSKVDSHRVKVAYGDEKTRFRMPKSWGYEDLLQEIARRFNVSDMSKFDVKYLDDDCEWVLLTCDADLEECIDVCQSSESGTIKLSLQPSSHSMRSSLEFR 908          

Query:    1 MEDGALTS-STTMMEAPQPDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSP-FSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQ---ESRSIVNVDGGSNQKEYRFETYSG-EGF---FSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVK-ARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIR---EKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGAS-STFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSS 2682
            M DGA+T+ S  MMEAP  +E SMDF+Y+S+LLLDGCWLEASADGS+FLLQ SP FS+PLFDPSF+WP+L+  +P    D+H+SQ+A LG  Q   +S+++VNV  G    +   ET+S  EG      RWWI PT + G G S I+EKLIRALKWIK F+ NKDMLIQIWVPV RGD RP L+AN+LPFSL++ S NLARYREIS  +QFSAEE DSK+LV GLPGRV+RDKVPEWTPDVRFFRSDEYPRV+HA+E DI GTLAVP+FEQGSRTCLGVIEVVMTTQQ NY  +LE+VCKALEVVDL S +HSS+QN K ARD+SYE ALPEIQEVLRSAC MHKLPLAQTW+ C QQGKDGCRHS+DNY+HCISPVE ACY+GD SVRFFHEACMEHHLLKGQGVAG AFM NQP FS DIT LSK DYPLSHHARLFGLRAAVAIRLRSIYS++DDYVLEFFLPV+CNDS EQK ML SLS+IIQR CR+LRVIT+KELE+ + S+ EVM L DSGFA    WSE QH    ASL+ +   +ET+GGKFS+  + QE+ ILKG+ E  RECS  VEGN LSSVGI    EKRR KADKTITL+VLRQYF GSLKDAAKNIGVCTTTLKR+CRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGAS ++F+IDSFYS   DLASPNLSG SL+S LNQ +N  SL+ QPD   LSPE A                      EQQ HT++ A NKDP+VG+DS DVVLKRIRSEAELKS     NKA + PRS S ETLGEH  TEY   LLKT  KA+ KEDAHRVKVTYGDEK+RFRMPK+W YE ++QEI RRFNVSDMSKFD+KYLDDD EWVLLTCDADLEECIDVC SSE STIKLC+Q SS
Sbjct:    1 MGDGAVTTTSAAMMEAPT-NETSMDFEYMSDLLLDGCWLEASADGSNFLLQQSPPFSSPLFDPSFSWPALETNEPTHVEDQHESQEAPLGNTQLVSQSQNMVNVVDGRYNNQSETETHSVVEGTSDGVKRWWIAPTCSPGLGPS-IMEKLIRALKWIKQFNWNKDMLIQIWVPVPRGD-RPILSANNLPFSLDSGSENLARYREISEGFQFSAEE-DSKELVPGLPGRVFRDKVPEWTPDVRFFRSDEYPRVEHAREFDICGTLAVPIFEQGSRTCLGVIEVVMTTQQINYVPQLESVCKALEVVDLTSLKHSSIQNAKQARDKSYEAALPEIQEVLRSACHMHKLPLAQTWVSCFQQGKDGCRHSEDNYLHCISPVEQACYVGDPSVRFFHEACMEHHLLKGQGVAGKAFMINQPFFSTDITMLSKTDYPLSHHARLFGLRAAVAIRLRSIYSSADDYVLEFFLPVNCNDSEEQKNMLISLSIIIQRCCRSLRVITDKELERTS-SSVEVMALEDSGFARTVKWSEPQHITSVASLEPEEKSSETVGGKFSDLREHQEDSILKGNIECDRECSPFVEGN-LSSVGISKTGEKRRAKADKTITLEVLRQYFPGSLKDAAKNIGVCTTTLKRVCRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASGASFKIDSFYSNFPDLASPNLSGASLVSALNQSENPNSLSIQPDLGPLSPEGATKSLSSSCSQGSLSSHSCSSMPEQQPHTSDVACNKDPVVGKDSADVVLKRIRSEAELKS--HSENKAKLFPRSLSQETLGEHTKTEYQSYLLKTCHKATPKEDAHRVKVTYGDEKTRFRMPKSWSYEHLLQEIARRFNVSDMSKFDVKYLDDDLEWVLLTCDADLEECIDVCLSSESSTIKLCIQASS 900          

Query:    1 MEDGALTSSTTMMEAPQPDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLD-----NIDPPDNVDRHKSQ--------DASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKEL-EKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGI---REKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHH-TNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFI 2691
            M+D  L+ +T M    QPD ++ D D++ EL L+GCWLE + DG +F  QS   S+   +PS  W  L+      ++P +N ++   Q        +  +  +  S+++++VDG S        T        RWWIGP  N GP  S ++E+L RAL  I++  R+K++L+Q+WVPVN+G  R  LT ND  FSL++    L++YR+ISV YQFS  E DS +LV GLPGRV+  +VPEWTPDVRFFRSDEYPRVD+AQ  D+ GTLA+P+FEQGSRTCLGVIEVV TTQ+  Y  ELE+VCKALE VDL+SSR+ S QNVK   + Y+ ALPEIQEVLR ACE HKLPLAQTW+ CIQQGKDGCRHSDDNYVHC+S V++A ++ D  +  F+EAC EHHLLKGQG+ G AFMTNQPCFS DITS  K +YPLSHHAR+FGL AAVAIRLRS+ + S D+VLEFFLPV+C D  EQKKML SLS+IIQ++CR+LRV+T+KEL E+++   +E++  +D   +  A+++E+       S+       E +G K S+  Q Q +  LK   + GRECS   EG+  SSVG+   REKRR KA+K ITL+VLR+YF+GSLKDAA +IGVC+TTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSV+GAS  FQI+SFY+   +L SPNLSGTS  ST    D  +  N  P+   +SP+                         QQH  T N     DP+VG++S D VLKR+RSEAEL +  QD  +  ++PRSQSH+ L E    +     LK +  A Q+ +  RVKV YGDEK+RFRM   W YED+VQEI +RF+V DMSKF IKYLDDD EWVLLTCDADLEECIDVC+SS+ +TIKL L  S + +
Sbjct:    1 MDDDVLSPATMM--GAQPD-SATDLDFMDELFLEGCWLETT-DGPEFPNQSHANSSAHINPSVFWHMLEANGNLTMNPSENSNQEVIQTPFFKQLHEGPVNPQFPSQNMIDVDGYSGHSAD--PTIKSYELNRRWWIGPLGNQGPASS-VMERLTRALVCIREVMRDKNVLVQVWVPVNKGG-RNVLTTNDDLFSLDSSCPRLSKYRDISVNYQFSTGE-DSTELVKGLPGRVFSGQVPEWTPDVRFFRSDEYPRVDYAQRYDVRGTLALPIFEQGSRTCLGVIEVVTTTQKIKYQLELESVCKALEAVDLQSSRNWSTQNVKGCVKPYQAALPEIQEVLRCACETHKLPLAQTWVSCIQQGKDGCRHSDDNYVHCVSTVDHAFHVTDPYIEGFYEACSEHHLLKGQGIVGKAFMTNQPCFSDDITSCVKTEYPLSHHARMFGLHAAVAIRLRSMKTGSTDFVLEFFLPVECRDPEEQKKMLNSLSLIIQQICRSLRVVTDKELEEESDFPVSEMIVSSDPRPSGIASFTEVHLSGNDVSIFPMENPREVLGVKSSKLRQHQPDSNLKVGVKCGRECSALGEGS-FSSVGVSKTREKRRTKAEKAITLEVLRKYFSGSLKDAANSIGVCSTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVEGASGAFQINSFYTNFPELTSPNLSGTSPFSTSKLSDQPMPTNLSPEGGVVSPQATTSKSPSSSCSQSSSSSQCCSSRTQQHRPTCNVTGGDDPIVGDNSGDGVLKRVRSEAELHAFGQD--RTQLLPRSQSHKILNELQKLQPIPPSLKNNGVA-QEGEVQRVKVAYGDEKTRFRMQSDWRYEDLVQEIAKRFSVEDMSKFYIKYLDDDSEWVLLTCDADLEECIDVCRSSQSNTIKLSLHLSRHHL 902          

Query:    1 MEDGALTSSTTMMEAPQPDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSL--DNIDPPDNVDRHKSQDASLG-------------TEQESRSIVNVDGGSNQKE-YRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQH-----------------RRMAASLD-----GDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVG-IREKRRPKADKTITLQVLRQYFAGSLKDAA-KNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSL 2703
            MEDGA    T +   P   ++SMD D++ EL L GCWLE + DGS+FLLQS   S  +FDPS  WP+   +N+D   N+  +  Q+ +               T+  S+S+ NV G   Q E Y  + +       RWWI P  + GP  S ++E+LIRAL +I+   +NKD LIQIWVPVNRG  R  LT ND PFSL+     LARYR+ISV YQFSAEE DS +L AGLPGRV+  KVPEWTPDVRFFRS+EYPRVD+AQ  D+ GTLA+PVFEQGS+TCLGVIEVVMTTQ+SNY  ELE+VCKALE VDLRSS   S +NVKA ++ Y+ ALPEI EVL SAC  H LPLAQTW+PCIQQGK G RH+D NY+HC+S V+ AC + D   + FHEAC EHHLLKGQG+AG AF TN+PCFSADITS SK  YPLSHHAR+FGL AAVAIRLRSI+    D+VLEFFLPVDC D  EQK ML SLS+IIQ+VCR+LRV+T+KELE    S    + +   G        ++QH                 +    S+D           E +  K  E  Q Q++   +G  +   + +       LSSVG   E+RR KA++TITLQVL+QYFAGSLKDAA K+IGVC TTLKRICRQHGIKRWPSRKIKKVGHSL K+QLVIDSV+GAS  FQI +FYSK  +LASP LSGT   ST    D+Q  L+ QP+ D+ S   A                       Q+H +    +  DP+VGE+S + +LKR+RSE EL   I    +  ++PRSQSH++L E P  E H ++ ++   ASQ+ DA RVKVTYGDEK RFRM   W  +D+ QEIGRRFN+ D S F +KYLDDD EWVLLTC+AD EEC D+C SS+   I+L +   S+ + SSL
Sbjct:    1 MEDGAPPPETALGTVP---DSSMDLDFMDELFLGGCWLETT-DGSEFLLQSPSNSGSVFDPSSLWPTFGSNNVDLSANLSANNIQEETQRSNFPGNAVESTDKTQSLSQSMTNVAGXPVQSENYLMDDFD---LSRRWWIRPKSSPGPS-STVMERLIRALSYIRGSTKNKDALIQIWVPVNRGGRR-VLTTNDQPFSLDPSCPRLARYRDISVNYQFSAEE-DSXEL-AGLPGRVFLGKVPEWTPDVRFFRSEEYPRVDYAQHFDVRGTLALPVFEQGSQTCLGVIEVVMTTQKSNYRPELESVCKALEAVDLRSSEVLSTRNVKACNKFYQAALPEILEVLTSACGTHGLPLAQTWVPCIQQGKWGSRHTDGNYIHCVSTVDSACCVADPRTQGFHEACSEHHLLKGQGIAGRAFTTNEPCFSADITSFSKTQYPLSHHARMFGLCAAVAIRLRSIHVPVSDFVLEFFLPVDCRDPEEQKGMLCSLSIIIQKVCRSLRVVTDKELEGETPSLVSELTVLSDGSPGREETQKVQHTPTEKISQEQSSWMASLKEAQQSIDITPPSQKEKVRERLSEKSLEFRQHQQDSSQQGSFDCRDDSTFGKSS--LSSVGKTGERRRSKAEQTITLQVLQQYFAGSLKDAAIKSIGVCPTTLKRICRQHGIKRWPSRKIKKVGHSLHKIQLVIDSVKGASGAFQIGNFYSKFPELASPELSGTHPYSTSKLFDHQKPLSVQPEGDNSSTGVAASKSLSSSCSPSSSSSQCCSTGTQEHPSTCSVTGSDPMVGENSAEGMLKRVRSEVELP--ISSQEELKLLPRSQSHKSLPECPNLESHPAIPQSGSLASQEGDAWRVKVTYGDEKIRFRMQSNWGLKDLRQEIGRRFNIDDSSGFHLKYLDDDLEWVLLTCEADFEECKDICGSSQNHVIRLAIHQISHHLGSSL 926          

Query:    1 MEDGALTSSTTMMEAPQPDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWP--SLDNID------------------PPDNVDRHKSQDAS-LGTE---QESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNN-LSANEVMDLAD----------------SGFASGATWSELQHRRMAASLDGDFFFNE----TMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGI---REKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNN----------FASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQ 2673
            ME+G  +  T +       +++MDFDY+ +LLL+GCWLE + DGS+F    SP S+  F  SF WP   ++N D                  P  N   +++QD S L TE   Q+  S+V +  G+N  E             RWWIGP+   GP  S + ++LI AL +IKDF ++KD+LIQIWVPVN G  R FL  +D  F++      LA YR+IS+ Y FSA+E +SKD+V GLPGRV+  KVPEWTPDVRFFRSDEYPRVDHAQ+  + GTLA+PVFEQGSRTCLGVIEVV T  +  Y  ELE+VC+ALE VDL+SS    +QNVK  D SY++ LPEI E+LRSACE H+LPLAQTW+PCIQQGK GCRHSD+NY+ C+S V+ ACY+ D+S++ FHEAC EHHLLKGQGVAG AF+TNQPCF++DITS +K +YPLSHHAR+FGLRAAVAIRLRS+++ + D+VLEFFLPVDC D  +QKKMLTSLS+IIQ+VCR+LRV+T+KELE+ N    +EV+D +D                  +A   +W+        +  DG     E     MG KF +  + QE+  LK + E G + S++ EG+  SSV +    EKRR KA+KTITLQVLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI RWPSRKIKKVGHSLQKLQLVIDSVQGAS + QI SFY+   +L SP LS +S  ST  Q ++       P+P S+ PE+                          H  ++            +++DP++GE   + +LKR+RS+AEL +  Q   + N++PRSQSH++L E P   Y   L KT   ASQ+ DA RVKVTYG+E  RFRMP +W   D++ EI RRFN+ D++++D+KYLDDD EWVLLTCD DLEEC+D+ +     T   C +
Sbjct:    1 MEEGVFSPGTMLGTRV---DSAMDFDYMDKLLLEGCWLE-TIDGSEFF-NPSPSSSAAFIDSFLWPIPEVNNDDLASTPSQKSNPEEEQIALPHRNSLLNETQDGSPLNTEAIGQDMGSVVTL--GNNAAE-------ASEVSRRWWIGPSAIPGPKTS-VRDRLITALSYIKDFTKDKDVLIQIWVPVNSGGRR-FLVTHDQHFAVVPNCERLANYRDISINYHFSADE-NSKDMV-GLPGRVFLGKVPEWTPDVRFFRSDEYPRVDHAQQYGVRGTLALPVFEQGSRTCLGVIEVVTTAHKIIYHPELESVCRALEAVDLQSSGIPGMQNVKVCDMSYQSVLPEIHELLRSACETHQLPLAQTWVPCIQQGKGGCRHSDENYIRCVSTVDRACYVRDTSIQVFHEACSEHHLLKGQGVAGEAFLTNQPCFTSDITSYAKTEYPLSHHARMFGLRAAVAIRLRSVHTGTADFVLEFFLPVDCTDPDKQKKMLTSLSIIIQQVCRSLRVVTDKELEEENYFLVSEVVDPSDGRLTRDEMLRVGHMYSESYAGDISWTSCLTVARQSGNDGSLCQIEKQKVPMGEKFMQHKKNQEDNSLKRNIECGGDSSVA-EGS-FSSVCMGKTAEKRRTKAEKTITLQVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGINRWPSRKIKKVGHSLQKLQLVIDSVQGASGSLQIGSFYTNFPELVSPKLSRSSQFSTSKQSEH-------PEPSSIQPEEGIFSSQAAAPKSPSPSSSCSQSSSSSHCVSSGTQKTPSSCTVPTSEDPMLGEG--NAILKRVRSDAELHASSQ--AEQNLLPRSQSHKSLREQPNLGYLPPLPKTSSCASQEIDAQRVKVTYGNENIRFRMPSSWGLTDLLGEIARRFNIDDINRYDLKYLDDDSEWVLLTCDDDLEECLDIVKQWHFMTSVACFE 918          

Query:   67 MDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFS----------------RWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKEL-EKNNLSANEVMDLADSGFASG----------------------ATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIR---EKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPS 2679
            MDFDY+ ELLL+GCWLE + DGS+FL  S   S   FD SF WP+     P  N     S  +  G  QE   I    G S   + +  + +GE   S                RWWIGPTPN     S +  +LI+AL+ IKD  +NKD+LIQIWVPVNRG  R  LT +D PFSL+  S  LA YR+ISV+YQFSAEE DSKD V GLPGRV+  KVPEWTPDVRFFRSDEYPRV+HAQ  D+ GTLA+PVFEQGSRTCLGVIEVV T+Q+  Y  ELE+VCKALE VDLRSS   S+QN++A + SY+ ALPEIQ++LR+ACE H+LPLAQTW+PC QQGK GCRHS++NY  C+S V+ AC + DS+++ F EAC EHHLLKGQGVAG AFMTNQPCFS D+TS  K +YPLSHHAR+FGL AAVAIRLRSIY  + D+VLEFFLPV+C D  EQKKML SLS IIQ V + LRV+T+KEL E+ +L  +EV+  +D G +SG                      A  SE+Q      SL         +  K SE  + QE+  L+   + GR+ S S EG+  SS G     EKRR KA+KTITLQVLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQ VIDSV+GAS T QIDSFY    +LASP LS TS +STL         ++ P P  + PE                             +   A+++DP+ GE+S + VLK +RS  EL +      +   MPRSQSH+TL E         L K   + SQ+ DAHR+KVTYG+E  R RM   W ++D++QEI RRFN+ D+ +FD+KYLDDD EWVLLTCD DLEECI +C SS+  TIKL L+ S
Sbjct:    1 MDFDYMDELLLEGCWLETT-DGSEFLNPSLSNSAAFFDSSFMWPT-----PEINHGDSASSPSQKGN-QEDNQISMFPGNSTLSDIQARSPAGETAVSVAGWDDNATDGSELGKRWWIGPTPNPSVETS-VKRRLIKALECIKDLTKNKDVLIQIWVPVNRGGRR-VLTTHDQPFSLDPSSEKLASYRDISVKYQFSAEE-DSKDSV-GLPGRVFLGKVPEWTPDVRFFRSDEYPRVNHAQLYDVRGTLALPVFEQGSRTCLGVIEVVTTSQKIKYRPELESVCKALETVDLRSSEVPSIQNLQACNMSYQAALPEIQKLLRAACETHRLPLAQTWVPCTQQGKGGCRHSNENYYRCVSTVDDACCVADSAIQGFQEACSEHHLLKGQGVAGQAFMTNQPCFSGDVTSYGKTEYPLSHHARMFGLCAAVAIRLRSIYIGTTDFVLEFFLPVNCRDPQEQKKMLNSLSAIIQHVSQTLRVVTDKELVEETDLPFSEVLVPSD-GRSSGEETSTVKQSCSERHSRDNSPWTACLSEVQPSGSNISLSQKDKQKVMLREKSSENRENQEDCSLRESIKCGRD-STSAEGS-FSSAGTSKTGEKRRAKAEKTITLQVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGINRWPSRKIKKVGHSLKKLQRVIDSVEGASGTVQIDSFYKNFPELASPTLSRTSPLSTLKS-------SSHPKPSGMQPEGGTFSSQVTAPKSPSPSCSLGSSSSHSCSSGAIAASEDPVSGENSGNGVLKMVRSNVELHA--SSPGEQERMPRSQSHKTLAE---LGSIPPLSKDGSRLSQETDAHRLKVTYGNEIIRLRMSNKWGFKDLLQEIVRRFNIDDIHRFDLKYLDDDSEWVLLTCDDDLEECIAICGSSDNQTIKLLLEVS 887          

Query:   52 PDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSL---DNIDPPDNVDRHKSQDASLGTEQESRSIVNVDG---------GSNQKEYRFETYSGEGFF-------SRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVG-IREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQ-------PDPD-SLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCL-QPSSNFIRSS 2700
            P +  MD DY+  L L+GCWLE + DG++FL  S    N  FD SF WP+    +N++      +   Q+    +  E+ SI +            G N       +   E           RWWIGP  +S      ++++LI AL +I+D  R+KD+L+Q+WVP+NR D R  L+  + PF L+     LA YRE+SV YQF A E DSK++V GLPGRV+ DKVPEWTPDVRFFRS+EYPRV+HAQ+ D+ GTLAVPVFEQGSR CLGVIEVVMTTQ+  Y +ELE+VCKALE VDL +S  S+ Q+ K  D SY+ ALPE+ EVL+SACE H LPLAQTW+PCIQQGK GCRHS +N +HC+S  + ACY+ D  V+ FH+AC EHHLLKGQGV G AF TNQPCFSAD+TS SK +YPLSH+A++FGL+AAVAIRLRSI + S D+VLEFFLP DC +  + +KMLTSLS+IIQ VCR LRV+T+KEL++  +S  E+ +            S  Q R    S D +F  +  M    + Q ++ + ++ K   E     + + E  +  ++G   ++RR KA+KTITLQVL+QYFAGSLKDAAK+IGVC TTLKRICRQHGIKRWPSRKIKKVGHSLQK+Q VIDSVQGAS T QI+SFYS   +LASPN S  S  +     ++  +LNTQ       P+PD S SP  +                        Q H  +   ++D +V E+SVD  +KR++SE EL      +     +PRSQSH  + E+PI+E    +LK     SQ E+A RVKVT+G+EK RFRM  +W Y D+++EI RRF + D S   +KYLDDD EWVLLTCDADLEECIDVC SS+I  IKL L Q S +   SS
Sbjct:   15 PSDYLMDLDYMDGLFLEGCWLETT-DGNEFLQHSPGIFNAPFDSSFMWPTTIDANNVEFNGISSKDAQQEKQRPSLTENLSINHCQELNYAKVQSFGENMNNAMCTSSLSENHLVEAHELNKRWWIGPKASSS-----VMDRLIWALGYIRDCSRDKDILLQLWVPINR-DGRRVLSTTNQPFLLDLNCPQLANYREVSVNYQFPANE-DSKEIV-GLPGRVFADKVPEWTPDVRFFRSEEYPRVEHAQQYDVRGTLAVPVFEQGSRNCLGVIEVVMTTQKIKYRSELESVCKALEAVDLSTSEVSTTQDAKVCDLSYQAALPEVLEVLKSACETHGLPLAQTWVPCIQQGKGGCRHSQENLIHCVSTEDSACYVADPRVQGFHDACSEHHLLKGQGVVGRAFNTNQPCFSADLTSYSKSEYPLSHYAKMFGLQAAVAIRLRSISTGSSDFVLEFFLPSDCRNPEDHRKMLTSLSIIIQNVCRTLRVVTDKELQEETISVGEMANHTVEQHKEHTETS--QERTSWTSCDAEFQESSVMS---TFQDEKPDEMLRKDSVEFRHRKNSAYEEGVSRNLGKTGDRRRAKAEKTITLQVLQQYFAGSLKDAAKSIGVCPTTLKRICRQHGIKRWPSRKIKKVGHSLQKIQRVIDSVQGASGTLQIESFYSNFPELASPNASRMSPFADSKSNEHPTALNTQQERCITSPNPDASKSPSSS----SSRSSSSSQCCSSGTKPQSPQSHPLSIVGDEDLIVQEESVDNAVKRVKSEPELH---LSSEALKTIPRSQSHLCVAENPISE--NLVLKRSPSTSQ-EEAPRVKVTHGEEKIRFRMQNSWRYNDLLREITRRFGIDDPSGLQLKYLDDDSEWVLLTCDADLEECIDVCMSSQIQMIKLILVQDSQHHFGSS 902          

Query:    1 MEDGALTSSTTMMEAPQPDENSMDFDYVSELLLDGCWLEASADGSDFL-LQSSPFSNPLFDP-SFTW-PSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGG-KFSEQTQQQENLIL---KGDTES-----GRECSLSVEGNL--------LSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDV--VLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSN 2685
            MED  L S   +M+A          D++  LLLDGCWLE + DGS+FL +  S  S   FDP SF W P+ D               ++L T      +   D         F+      +  RWWIGP    G GGS + E+L++A++ IKD+   +  LIQ+WVPVNRG  R  LT  + PFS +     LA YREISV Y FSAE++DSK L AGLPGRV+  K+PEWTPDVRFF+S+EYPRV HAQ+CD+ GTLA+PVFEQGS+ CLGVIEVVMTT+      ELE++C+AL+ VDLRS+      ++K  D SY+ ALPEI+ +LR ACE HKLPLAQTW+ C QQ K GCRH+D+NY+HC+S ++ ACY+GD +VR FHEAC EHHLLKGQGVAG AF+TN PCFS+D+++  K +YPLSHHA ++GL  AVAIRLR I++ S D+VLEFFLP DC+D  EQ+KML +LS I+  V R+LR +T+KELE+ +        +            ++++   A+ L G+  +N ++   + S  T   +NL L    GD  +      R    +++ N+             + EK+R KADKTITL VLRQYFAGSLKDAAKNIGVC TTLKRICRQHGI+RWPSRKIKKVGHSLQK+Q VIDSVQG S    I SFY+   +L S +   +    T       V L                  + S   S   S + S     +   N+ A+   P     S DV   LK+  SE EL+S   D     +     S E + +            T+  +SQ +D  R+KV+YG+EK R RM  +    D++ EIG+RF++ DMS++D+KYLD+D EWVLLTCD D+EEC+DVC+++   TIKL LQ SS+
Sbjct:    1 MEDSFLQSENVVMDA----------DFMDGLLLDGCWLETT-DGSEFLNIAPSTSSVSPFDPTSFMWSPTQDT--------------SALCTSGVVSQMYGQDCVERSSLDEFQ------WNKRWWIGP----GGGGSSVTERLVQAVEHIKDYTTARGSLIQLWVPVNRGGKR-VLTTKEQPFSHDPLCQRLANYREISVNYHFSAEQDDSKAL-AGLPGRVFLGKLPEWTPDVRFFKSEEYPRVHHAQDCDVRGTLAIPVFEQGSKICLGVIEVVMTTEMVKLRPELESICRALQAVDLRSTELPIPPSLKGCDLSYKAALPEIRNLLRCACETHKLPLAQTWVSCQQQNKSGCRHNDENYIHCVSTIDDACYVGDPTVREFHEACSEHHLLKGQGVAGQAFLTNGPCFSSDVSNYKKSEYPLSHHANMYGLHGAVAIRLRCIHTGSADFVLEFFLPKDCDDLEEQRKMLNALSTIMAHVPRSLRTVTDKELEEESEVIEREEIVT----------PKIEN---ASELHGNSPWNASLEEIQRSNNTSNPQNLGLVFDGGDKPNDGFGLKRGFDYTMDSNVNESSTFSSGGFSMMAEKKRTKADKTITLDVLRQYFAGSLKDAAKNIGVCPTTLKRICRQHGIQRWPSRKIKKVGHSLQKIQRVIDSVQGVSGPLPIGSFYANFPNLVSQSQEPSQQAKTTPPPPPPVQL------------------AKSPVSSYSHSSNSSQCCSSETQLNSGATTDPP-----STDVGGALKKTSSEIELQSSSLDETILTL----SSLENIPQ-----------GTNLLSSQDDDFLRIKVSYGEEKIRLRMRNSRRLRDLLWEIGKRFSIEDMSRYDLKYLDEDNEWVLLTCDEDVEECVDVCRTTPSHTIKLLLQASSH 829          

Query:   52 PDENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPS-FTWPSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDS----KDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLS-ANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVG----IREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASS-TFQIDSFYSKLSDLASPNLSGTSLISTLNQ 2055
            P + +MD  ++  LLL+GCWLE + D S+FL  S   S   FDPS F W      D  +++ +   QD       E  S+ + + G +             F  RWWIGP   SG  G  ++E+L++A+  IKDF   +  LIQ+WVPV+RG  R  LT  + PFS +     LA YREIS  YQFS E+EDS    +DLV GLPGRV+  KVPEWTPDVRFF+++EYPRV HAQ+CD+ GTLA+PVFEQGS+ CLGVIEVVMTTQ    S +LE++C+AL+ VDLRS+      ++K  D SY+ ALPEI+ +LR ACE HKLPLAQTW+ C++Q K GCRH+D+NY+HC+S ++ ACY+GD +VR FHEAC EHHLLKGQGV G AF+TN PCFS+D++S  K +YPLSHHA +FGL   VAIRLR I++ S D+VLEFFLP +C D  EQ+KML +LS I+  V R+LR +T KELE+   S  +EV++        G T  ++++      +       + +G  F   T +   L     +E G+  S++ E N  SS      + EK+R KA+K ITL VLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI+RWPSRKIKKVGHSLQK+Q VIDSV+G S     I SFY+       PNL+ +   S+L Q
Sbjct:    7 PMDPAMDSSFMDGLLLEGCWLETT-DASEFLNFSPSTSVAPFDPSSFMWSPTQ--DTSNSLSQMYGQDCP-----ERSSLEDQNQGRDLST----------FNRRWWIGP---SGHHGFSVMERLVQAVTHIKDFTSERGSLIQLWVPVDRGGKR-VLTTKEQPFSHDPMCQRLAHYREISENYQFSTEQEDSDSSSRDLV-GLPGRVFLGKVPEWTPDVRFFKNEEYPRVQHAQDCDVRGTLAIPVFEQGSQICLGVIEVVMTTQMVKLSPDLESICRALQAVDLRSTEIPIPPSLKGPDFSYQAALPEIRNLLRCACETHKLPLAQTWVSCLKQSKTGCRHNDENYIHCVSTIDDACYVGDPTVREFHEACSEHHLLKGQGVVGEAFLTNGPCFSSDVSSYKKSEYPLSHHATMFGLHGTVAIRLRCIHTGSVDFVLEFFLPKNCRDIEEQRKMLNALSTIMAHVPRSLRTVTQKELEEEGDSMVSEVIE-------KGVTLPKIEN---TTEVHQSISTPQNVGLVFDGGTTEMGEL----GSEYGKGVSVN-ENNTFSSASGFNRVTEKKRTKAEKNITLDVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGIQRWPSRKIKKVGHSLQKIQRVIDSVEGVSGHHLPIGSFYASF-----PNLAASPEASSLQQ 642          

Query: 2410 ASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIK 2661
            +SQ++D  RVKV+Y +EK RF+M  +   +D++ EI +RF++ D+S++D+KYLD+D EWVLL CD D+EEC+DVC+S    TIK
Sbjct:  704 SSQEDDFLRVKVSYEEEKIRFKMRNSHRLKDLLWEIAKRFSIEDVSRYDLKYLDEDNEWVLLRCDDDVEECVDVCRSFPGQTIK 787          

Query:   58 ENSMDFDYVSELLLDGCWLEASADGSDFLLQSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRH---SSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRV-ITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGK----------------------------------FSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSS 2682
            + +MD D++ ELL DGCWLE +   S    + SP ++          ++++  P      + SQD +   E+  R     +     K    E   G+     WWI P+ + GP  S + E+L++A+  + +  ++KD L+QIWVP+ + + + FLT    P        +LA YR +S  Y F A+E   KD V GLPGRV+  K PEWTPDVRFFR DEYPR+  AQ+CD+ G+LA+PVFE+GS TCLGV+E+V TTQ+ NY  ELE +CKALE VDLRSS +    S + ++     Y  ALPEI++ L + C  +  PLA +W PC +QGK G RHSD+N+  C+S ++ AC + D   + F EAC EHHLL+G+G+ G AF   +  F  ++ + SK +YPL+HHA++ GL AA+A+ L+S  S   ++VLEFF P  C D+  Q++ML SL + +Q+  R+  + I + ELE   L   E M  +++      T   L   +M  S            GK                                   +EQ QQ     L+ D     E + +  GN+LSS    EK+R K +KTI L+VLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQLV+DSVQGA  + Q+DSFY+   +L SPN+S      +L   +    LN Q D   ++ E+            S S    S  S    +T N       LV ED+ D VLKR  SEA+L ++ Q+  K   + R+QSH+T  E  + +    L  +   + +   A +VK T+G+ + RF +  +W + ++ QEI RRFN+ D+S FD+KYLDDD EWVLLTC+ADL ECID+ + ++  TIK+ L  +S
Sbjct:   27 DTAMDLDFMDELLFDGCWLETTDSKSLKQTEQSPSAST---------AMNDNSPFLCFGENPSQD-NFSNEETERMFPQAE-----KFLLEEAEVGKS----WWIAPSASEGPSSS-VKERLLQAISGLNEAVQDKDFLVQIWVPIQQ-EGKSFLTTWAQPHLFNQEYSSLAEYRHVSETYNFPADE-GMKDFV-GLPGRVFLQKFPEWTPDVRFFRRDEYPRIKEAQKCDVRGSLALPVFERGSGTCLGVVEIVTTTQKMNYRQELEKMCKALEAVDLRSSSNLNTPSSEFLQVYSDFYCAALPEIKDFLATICRSYDFPLALSWAPCARQGKVGSRHSDENFSECVSTIDSACSVPDEQSKSFWEACSEHHLLQGEGIVGKAFEATKLFFVPEVATFSKTNYPLAHHAKISGLHAALAVPLKS-KSGLVEFVLEFFFPKACLDTEAQQEMLKSLCVTLQQDFRSSNLFIKDLELEV-VLPVRETMLFSENLLCGAETVESLTEIQMQESSWIAHMIKANEKGKDVSLSWEYQKEDPKELSSGRENSQLDPVPNNVPLEAEQLQQASTPGLRVDIGPSTESASTGGGNMLSSRRPGEKKRAKTEKTIGLEVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGIMRWPSRKIKKVGHSLKKLQLVMDSVQGAQGSIQLDSFYTSFPELNSPNMSSNG--PSLKSNEQPSHLNAQTDNGIMAEENP--------RSPSSSCSKSSGSSNNNENTGNI------LVAEDA-DAVLKRAHSEAQLHNVNQEETKC--LARTQSHKTFKEPLVLDNSSPLTGSSNTSLRARGAIKVKATFGEARIRFTLLPSWGFAELKQEIARRFNIDDISWFDLKYLDDDKEWVLLTCEADLVECIDIYRLTQTHTIKISLNEAS 895          

Query:   70 DFDYVSELLLDGCWLEASADGSDFLL--QSSPFSNPLFDPSFTWPSLDNIDPPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNK------DMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKEL--------------EKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGK----------FSEQTQQQENLILK----------GDTESG---------RECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPD-PD--------SLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTN-NFASNKDPLVGEDSVDVVLKRI-RSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPS 2679
            D D + E LL         D S+F     +SPFS PLFD   +  +L    P    D           E  SR    ++     + + F+T   E       + PT         + E+L RAL+ I    +++      ++L+Q+WVP   GD R  LT    PF L+ R+  LA YR +S++YQFSA+E    DL  GLPGRV+  +VPEWTPDVR+F ++EYPRV HAQ  DI G++A+PVFE  SR CLGV+E+VMTTQ+ NYSAE+E +C AL+ VDLRSS  SS    K  D SY   +PEI +VLR+ C+ H LPLAQTWIPCI Q K G RHSD++Y HC+S V+ ACY+ D SV  FH+AC EHHL +G+GV G AF TN+PCFS DIT+ SK  YPLSHHA+LFGLRAAVAI+LRS+ + S D+VLEFFLP+ C ++ EQ+ ML SLS  IQ+VC  LRV+  KEL              E    S +E +D   SG       + L+     +S        +  GGK          FS+Q  +  ++             G   SG         +E + S + +  +S    EKRR K +KT++LQ LR++FAGSLK+AAKN+GVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQ+VIDSV G   T Q+ S Y   +       S   L   ++   ++ +   +P  PD        S +    S SPS S S +S    S    ++QQH +    A  ++  + E+    ++K    +EAEL+  +++  +  ++ RSQS   L EH   E   ++ K       + D+ ++K  YG+E+  FR+  +W ++ + +EI +RF +S  +  D+KYLDD+ EWVLLTCDADL ECIDV +SS   T+++ + PS
Sbjct:   35 DLDLMEEFLL----ATPGFDLSEFWHPGAASPFS-PLFDIGSSVTTLTTPAPAAGEDDRDE------AEMPSRGGGGLEVSPAHRGWTFQTAPQE-----VAVEPT---------VKERLRRALERIASQSQSQAQRGDGELLVQVWVPTRIGD-RQVLTTCGQPFWLDRRNQRLANYRTVSMKYQFSADESARADL--GLPGRVFVGRVPEWTPDVRYFSTEEYPRVQHAQYFDIRGSVALPVFEPRSRACLGVVELVMTTQKVNYSAEIENICNALKEVDLRSSDVSSDPRSKVVDASYRAIIPEIMDVLRAVCDTHNLPLAQTWIPCICQAKRGSRHSDESYKHCVSTVDEACYVRDCSVLGFHQACSEHHLFRGEGVVGRAFGTNEPCFSPDITTYSKTQYPLSHHAKLFGLRAAVAIQLRSVKTGSLDFVLEFFLPMKCINTEEQRAMLNSLSNTIQQVCYTLRVVKPKELVNDGPFEISQPTRPEFYAKSVHEDLDELCSGINVPGRTTSLEASEEVSSWIASLVDAQNKGGKGEIDVDLPFGFSKQDDEGFSVTAGWHTSPVMAPDGSMFSGFKRHEDYDVKENTCSSDPSNSNSDKAVEKRRTKTEKTVSLQDLRKHFAGSLKEAAKNLGVCPTTLKRICRQHGINRWPSRKIKKVGHSLKKLQMVIDSVHGPEGTVQLSSLYENFTKT---TWSERELQGDVHFPASEQNFQLEPSVPDRPCEGRFTSHTSGSNSISPSCSQSSNSSLGCSSVPKTQQQHGSAPQLAVKEEISMDENQCSTLIKSASHAEAELQMFVEE--RPTMLFRSQSQVLLSEHKPIENMSNVQKA------RSDSLKIKAIYGEERCIFRLQPSWGFQRLKEEIVKRFGISQDTHVDLKYLDDESEWVLLTCDADLLECIDVYKSSSNQTVRILVNPS 927          

Query:  415 EKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPC-----IQQG---KDGCRHSDDNYVH--CISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATW--SELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTES-----GRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLSGTSL-ISTLNQIDNQVSLNTQPDPDS 2100
            E+L +AL++ K+   ++ +L+Q+W PV  GD R  LT +  PF L+ +S+ L +YR +S+ Y FS + E++ +L  GLPGRVY+ KVPEWTP+V+++ S EYPR++HA   ++HGT+A+PVF+   + C+ V+E++MT+++ NY+ E++ VCKALE V+L+S+      NV+  +   ++AL EI E+L   CE HKLPLAQTW+PC     +  G   K  C   D + +   C+S  + A ++ D+ +  F +AC+EHHL KGQGV+G AF+  +PCFS DI+   K++YPL H+AR+FGL    AI L+S+Y+  DDY+LEFFLP +C +  +Q  +L S+   +++  R L+V+ N +  +  L  + V+ +      +   +  SE   R    S +G    +E            + +L+   ++++     GR        +L  S    E+RR KA+KTI+L VL+QYF+GSLK+AAK++GVC TT+KRICRQHGI RWPSRKI KV  SL KL+ VI+SVQG+ + F + S    L     P+    +L  ++ N++    +L  + D DS
Sbjct:  137 ERLTQALRYFKE-STDQHLLVQVWAPVKSGD-RYVLTTSGQPFVLDQQSIGLLQYRAVSMMYMFSVDGENAGEL--GLPGRVYKQKVPEWTPNVQYYSSTEYPRLNHAISYNVHGTVALPVFDPSVQNCIAVVELIMTSKKINYAGEVDKVCKALEAVNLKSTEILDHPNVQICNEGRQSALVEILEILTVVCEEHKLPLAQTWVPCKYRSVLAHGGGVKKSCLSFDGSCMGEVCMSTSDVAFHVIDAHMWGFRDACVEHHLQKGQGVSGKAFIYRRPCFSKDISQFCKLEYPLVHYARMFGLAGCFAICLQSMYTGDDDYILEFFLPPNCRNEDDQNALLESILARMKKCLRTLKVVGNGDTNEVCLQISNVLIIETEDLKTNVHFENSEGCFRESPES-NGSQRVHEVDNDGNKVSIMSERHLLADDNSQNNGASVGRPNGSGASDSLHKSNKPPERRRGKAEKTISLDVLQQYFSGSLKNAAKSLGVCPTTMKRICRQHGISRWPSRKINKVNRSLSKLKQVIESVQGSDAAFNLTSITGPLPIPVGPSSDSQNLEKASPNKVAELSNLAVEGDRDS 711          

Query: 2437 VKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEI 2649
            +K ++ ++  RFR P +     +  E+ +R  + D+  FDIKYLDDD EWV L C+ADLEEC+++  S  I
Sbjct:  850 IKASFKEDIVRFRFPCSGSVTALKDEVAKRLRM-DVGMFDIKYLDDDHEWVKLACNADLEECMEISGSHVI 919          

Query:  364 WWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPV-NRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQG--------KDGCRHSDDNYVH--CISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVMDLADSGFASGATWSELQHRRM--AASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSF 1986
            W I P  N     + I  K+ +AL++ K+    + +L Q+W PV NRG  R  LT +  PF L   S  L +YR +S+ Y FS + E   +L  GLPGRV+R K+PEWTP+V+++ S E+ R+ HA   ++ GTLA+PVFE   + C+GV+E++MT+ + NY+ E+E VCKALE V+L++S   + +  +  +   + AL EI E+L   CE +KLPLAQTW+PC  +         K  C   D + +   C+S  + A Y+ D+ V  F +AC EHHL KGQGVAG AF +   CF  D+T   K DYPL H+AR+F L +  A+ L+S Y+  D+YVLEFFLP    D  EQ  +L SL   +++   +L+V++  EL +NN+S  EV++ ++ G      +S+L+  R+   A +  D+        K S  +   EN  +    E  +      E     +V   E++R K +KTI+L+VL+QYFAGSLKDAAK++GVC TT+KRICRQHGI RWPSRKI KV  SL +L+ VIDSVQGA  +  + S 
Sbjct:   90 WGIMPLENPDSYCA-IKAKMTQALRYFKESTGQQHVLAQVWAPVKNRG--RYVLTTSGQPFVLGPNSNGLNQYRMVSLTYMFSLDGERDGEL--GLPGRVFRKKLPEWTPNVQYYSSKEFSRLGHALHYNVQGTLALPVFEPSRQLCVGVVELIMTSPKINYAPEVEKVCKALEAVNLKTSEILNHETTQICNEGRQNALAEILEILTVVCETYKLPLAQTWVPCRHRSVLAFGGGFKKSCSSFDGSCMGKVCMSTSDLAVYVVDAHVWGFRDACAEHHLQKGQGVAGRAFQSGNLCFCRDVTRFCKTDYPLVHYARMFKLTSCFAVCLKSTYTGDDEYVLEFFLPPAITDKSEQDCLLGSLLQTMKQHYSSLKVVSETELCENNMSL-EVVEASEDGMV----YSKLEPIRIHHPAQISKDYLELNAPEQKVSLNSDFMENNEVDDGVERFQTLDPIPEAK---TVKKSERKRGKTEKTISLEVLQQYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKVNRSLTRLKHVIDSVQGADGSLNLTSL 630          

Query: 2437 VKVTYGDEKSRFRM-PKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKL 2664
            +K TY ++  RF++ P++    ++ Q++ +R  + + + F++KYLDDD EWV ++CDADL EC+D   +++ +T++L
Sbjct:  744 IKATYREDIIRFKISPESVSITELKQQVAKRLKL-ETAAFELKYLDDDREWVSVSCDADLSECLDT-SAAKANTLRL 818          

Query:  409 IVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQG---------KDGCRHSDDNYVH--CISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKEL--EKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFY----------SKLSDLASPNLSGTSLISTLNQIDNQVSLNTQPDPDSLSPE 2112
            I E++ +AL++ K+    + +L Q+W PV R + R  LT    PF L      L +YR IS+ Y FS + E   D+  GLPGRV+R K+PEWTP+V+++ S E+ R+DHA   ++ GTLA+PVF    ++C+GV+E++MT+++ +Y+ E++ VCKALE V+L+SS     Q  +  + S + AL EI EVL   CE H LPLAQTW+PC Q G         K  C   D + +   C+S  + ACY+ D+ V  F +AC+EHHL KGQGVAG AF+    CF  DIT   K  YPL H+A +F L    AI L+S Y+  D Y+LEFFLP    D  EQ  +L S+ + ++   ++LRV +  +   + + LS   +  L D         S+++  R+  S    F  N T       +T      +++       + +++    ++      EK+R K +KTI+L VL+QYF GSLKDAAK++GVC TT+KRICRQHGI RWPSRKIKKV  S+ KL+ VI+SVQG      + S            +    L SPN S    +   N   N  S +  P+  + SPE
Sbjct:  147 IKERMTQALRYFKE-STEQHVLAQVWAPV-RKNGRDLLTTLGQPFVLNPNGNGLNQYRMISLTYMFSVDSE--SDVELGLPGRVFRQKLPEWTPNVQYYSSKEFSRLDHALHYNVRGTLALPVFNPSGQSCIGVVELIMTSEKIHYAPEVDKVCKALEAVNLKSSEILDHQTTQICNESRQNALAEILEVLTVVCETHNLPLAQTWVPC-QHGSVLANGGGLKKNCTSFDGSCMGQICMSTTDMACYVVDAHVWGFRDACLEHHLQKGQGVAGRAFLNGGSCFCRDITKFCKTQYPLVHYALMFKLTTCFAISLQSSYTGDDSYILEFFLPSSITDDQEQDLLLGSILVTMKEHFQSLRVASGVDFGEDDDKLSFEIIQALPDK-----KVHSKIESIRVPFS---GFKSNAT-------ETMLIPQPVVQSSDPVNEKINVATVNGVVKEKKKTEKKRGKTEKTISLDVLQQYFTGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKIKKVNRSITKLKRVIESVQGTDGGLDLTSMAVSSIPWTHGQTSAQPLNSPNGSKPPELPNTNNSPNHWSSDHSPNEPNGSPE 717          

Query: 2437 VKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSSNFIRSSLE 2706
            +K +Y D+  RFR+       ++  E+ +R  V D   FDIKYLDDD EWVL+ CDADL+EC+++ +SS    ++L +   +  + SS E
Sbjct:  866 IKASYKDDIIRFRISSGSGIMELKDEVAKRLKV-DAGTFDIKYLDDDNEWVLIACDADLQECLEIPRSSRTKIVRLLVHDVTTNLGSSCE 954          

Query:  400 GSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQ-------GKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELEKNNLSANEVM-DLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGK-------FSEQTQQQENLILKGDTESGRECSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLAS 2013
            GS + ++++ AL   ++       L Q+W+PV + +    L+  + PF L+     LA YRE+S  + FSA+EE    L  GLPGRV+   VPEWT  V ++   EY R++HA   +I G+LA+P+++    +C  V E+V   ++ ++SAE++ VC AL+ V+L++++ SS Q     ++ +  A  EI +VLR+ C  H LPLA TW+P           GKDG   S       I   E ACY+ D  ++ F +AC   HL KGQG+AG A  +N P FS DI   S  DYPL+HHAR F L AAVAIRLRS Y+ +DDY+LEFFLPV C  SGEQ+ +L +LS  +QR+C++LR +   E++  N     V     +S   +G T S     +   S+ G  F + ++  K        +EQ Q                          SS+G  EK+R  A+K I+L VLR+YF+GSLKDAAK++GVC TTLKRICR HGI RWPSRKI KV  SL+K+Q VI+SV G   + Q D     L  + S
Sbjct:  136 GSSLADRMLMALSLFRE-SLGSGALAQVWMPVEQ-EGHVVLSTCEQPFLLDQV---LAGYREVSRHFVFSAKEEPG--LQPGLPGRVFISGVPEWTSSVLYYNRPEYLRMEHALHHEIRGSLAMPIYDPSKDSCCAVFELVTRKEKPDFSAEMDNVCNALQAVNLKATKGSSNQKFYTENQKF--AFTEILDVLRAICHAHMLPLALTWVPTSNGIDGGYVVGKDGASFSQSGKT-IIRIHESACYVNDGKMQGFLQACARRHLEKGQGIAGRALKSNLPFFSPDIREYSIEDYPLAHHARKFSLHAAVAIRLRSTYTGNDDYILEFFLPVSCKGSGEQQMLLNNLSSTMQRICKSLRTVYEAEVDNVNAGTAAVFRKNNESCLPTGHTESSSHGDQ---SITGASFEDTSLANKPGVMEPELAEQVQP-------------------------SSIGHAEKKRSTAEKNISLDVLRKYFSGSLKDAAKSLGVCPTTLKRICRHHGISRWPSRKINKVNRSLKKIQTVINSVHGVDRSLQYDPATGSLVPVVS 650          

Query: 2428 AHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKL 2664
            A  VK TY  +  RF+   +  +  +++EI +RF +     + +KY DD+ EWV+L  D+DL+EC+DV  S     +KL
Sbjct:  834 ALTVKATYNGDTVRFKFLPSMGWYHLLEEIAKRFKLP-TGAYQLKYKDDEDEWVILANDSDLQECVDVLDSIGSRIVKL 911          

Query:   58 ENSMDFDYVSELLLDGCWLEASADGSDF---LLQSSPFSNPLFDPS-----FTWPSLDNID-------------PPDNVDRHKSQDASLGTEQESRSIVNVDGGSNQKEYRFETYSGEGFFSRWWIGPTPNSGPGGSFIVEKLIRALKWIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRH---SSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCIQQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVITNKELE 1476
            +++MD D++ ELL DGCWLE + DG      + Q    S  + D +     + +   +N+              PP      K +D S     +  +++     S+ +  +F     EG   R+WI P  + GP  S + E+L++A++ + +  ++KD LIQIW+P+ + + + FLT ++ P     +  +L RYR++SV Y F A+E DSK+ V GLPGRV+  K+PEWTPDVRFFRS+EYPR+  A++CD+ G+LA+PVFE+GS TCLGV+E+V TTQ+ NY  EL+ +CKALE V+LRSSR     S + ++  +  Y  ALPE+ E L   C ++ LPLA TW PC +QGK G RHSD+N+  C+S V+ AC + D   R F EAC EHHLL+G+G+ G AF   +  F  ++T+ SK +YPL+HHA++ GL AA+A+ L++ +++S ++VLEFF P  C D+  Q+ ML SLS  +Q+  R+L +  +KELE
Sbjct:   23 DSAMDMDFMDELLFDGCWLETT-DGKSLKQTMGQQVSDSTTMNDNNNNSYLYGYQYAENLSQDHISNEETGRKFPPIPPGFLKIEDLSNQVPFDQSAVM-----SSAQAEKFLLEESEGG-RRYWIAPRTSQGPSSS-VKERLVQAIEGLNEEVQDKDFLIQIWLPIQQ-EGKNFLTTSEQPHFFNPKYSSLKRYRDVSVAYNFLADE-DSKESV-GLPGRVFLKKLPEWTPDVRFFRSEEYPRIKEAEQCDVRGSLALPVFERGSGTCLGVVEIVTTTQKMNYRPELDNICKALESVNLRSSRSLNPPSREFLQVYNEFYYAALPEVSEFLTLVCRVYDLPLALTWAPCARQGKVGSRHSDENFSECVSTVDDACIVPDHQSRHFLEACSEHHLLQGEGIVGKAFNATKLFFVPEVTTFSKTNYPLAHHAKISGLHAALAVPLKNKFNSSVEFVLEFFFPKACLDTEAQQDMLKSLSATLQQDFRSLNLFIDKELE 508          

Query: 1624 SEQTQQQENLILKGDTESGRE-CSLSVEGNLLSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIGVCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDSFYSKLSDLASPNLS--GTSLISTLNQIDNQVSLNTQPDPDSLSPEDAXXXXXXXXXXXXXXXXXXXXXXEQQHHTNNFASNKDPLVGEDSVDVVLKRIRSEAELKSLIQDNNKANVMPRSQSHETLGEHPITEYHQSLLKTDRKASQKEDAHRVKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQPSS 2682
            +EQ Q+  N  L+ D +   E  S  V   LL S    EKRR K +KTI L+VLRQYFAGSLKDAAK+IGVC TTLKRICRQHGI RWPSRKIKKVGHSL+KLQLVIDSVQG   + Q+DSFY+   +L+SP++S  GTS  +   Q +N VS        + +P+     PS+SCS SS SS  CS+ + Q  +T   ++    L+ E++   +LKR RSE  L ++ QD  K+  + R+ SH+T  EHP+ E    L +   +  +   A +VK T+G+ K RF +  TW + ++  EI RRFN+ +++ FD+KYLDDD EWVLLTC+ADLEECID+ +SS+  TIK+ +  +S
Sbjct:  601 AEQFQKVTNSGLRIDMDPSFESASFGVGQTLLGSRRPGEKRRTKTEKTIGLEVLRQYFAGSLKDAAKSIGVCPTTLKRICRQHGITRWPSRKIKKVGHSLKKLQLVIDSVQGVQGSIQLDSFYTSFPELSSPHMSGTGTSFKNPNAQTENGVSAQG----TAAAPKSP---PSSSCSHSSGSSTCCSTGANQSTNTGTTSNTVTTLMAENA-SAILKRARSEVRLHTMNQDETKS--LSRTLSHKTFSEHPLFENPPRLPENSSRKLKAGGASKVKATFGEAKVRFTLLPTWGFRELQHEIARRFNIDNIAPFDLKYLDDDKEWVLLTCEADLEECIDIYRSSQSRTIKISVHEAS 946          

Query:  415 EKLIRALK-WIKDFDRNKDMLIQIWVPVNRGDDRPFLTANDLPFSLETRSLNLARYREISVRYQFSAEEEDSKDLVAGLPGRVYRDKVPEWTPDVRFFRSDEYPRVDHAQECDIHGTLAVPVFEQGSRTCLGVIEVVMTTQQSNYSAELETVCKALEVVDLRSSRHSSLQNVKARDRSYETALPEIQEVLRSACEMHKLPLAQTWIPCI--QQGKDGCRHSDDNYVHCISPVEYACYIGDSSVRFFHEACMEHHLLKGQGVAGGAFMTNQPCFSADITSLSKIDYPLSHHARLFGLRAAVAIRLRSIYSTSDDYVLEFFLPVDCNDSGEQKKMLTSLSMIIQRVCRNLRVI-----TNKELEKNNLSANEVMDLADSGFASGATWSELQHRRMAASLDGDFFFNETMGGKFSEQTQQQENLILKGDTESGRECSLSVEGNL---LSSVGIREKRRPKADKTITLQVLRQYFAGSLKDAAKNIG-------------VCTTTLKRICRQHGIKRWPSRKIKKVGHSLQKLQLVIDSVQGASSTFQIDS 1983
            EK+++AL  +++     + +L Q+W P+  GD    L+  D  + L+ R    ++YRE+S R+ F+AE         GLPGRV+   VPEWT +V ++++DEY R+ HA + ++ G++A+P+ E    +C  V+E+V + ++ N+  E+++VC+AL+ V+LR++     Q + +  R    AL EIQ+VLR+ C  HKLPLA  WIPC   Q  +   + S +N + CI   E ACY+ D  +  F  AC+EH L + +G+ G AF++NQP FS+D+ +    +YP+  HAR +GL AAVAI+LRS Y+  DDY+LE FLPV    S EQ+ +L SLS  +QR+CR LR +     T KE  K    ++++     S F    +    Q      SLD +F    +M   FS  +  +EN I               +G L   +S     EK++   +K ++L  L+Q+F+GSLKDAAK++G              C TTLKRICRQHGI RWPSRKI KV  SL+K+Q V+DSVQG     + DS
Sbjct:  165 EKMLKALSLFMESSGSGEGILAQVWTPIKTGDQY-LLSTCDQAYLLDPR---FSQYREVSRRFTFAAEANQCS--FPGLPGRVFISGVPEWTSNVMYYKTDEYLRMKHAIDNEVRGSIAIPILEASGTSCCAVMELVTSKEKPNFDMEMDSVCRALQAVNLRTAAIPRPQYLSSSQRD---ALAEIQDVLRTVCHAHKLPLALAWIPCRKDQSIRVSGQKSGENCILCIE--ETACYVNDMEMEGFVHACLEHCLREKEGIVGKAFISNQPFFSSDVKAYDISEYPIVQHARKYGLNAAVAIKLRSTYTGEDDYILELFLPVSMKGSLEQQLLLDSLSGTMQRICRTLRTVSEVGSTKKEGTKPGFRSSDM-----SNFPQTTSSENFQ----TISLDSEFNSTRSM---FSGMSSDKENSITVS------------QGTLEQDVSKARTPEKKKSTTEKNVSLSALQQHFSGSLKDAAKSLGGETSAYFQAWVYFFCPTTLKRICRQHGIMRWPSRKINKVNRSLRKIQTVLDSVQGVEGGLKFDS 676          

Query: 2437 VKVTYGDEKSRFRMPKTWCYEDVVQEIGRRFNVSDMSKFDIKYLDDDCEWVLLTCDADLEECIDVCQSSEISTIKLCLQ 2673
            VK +Y ++  RF+   +     + +E+G+RF + D S F +KYLDD+ EWV+L  D+DL+EC+++       ++K  ++
Sbjct:  850 VKASYREDTVRFKFEPSVGCPQLYKEVGKRFKLQDGS-FQLKYLDDEEEWVMLVTDSDLQECLEILHGMGKHSVKFLVR 927