Ca_07442, Ca_07442_v1.0_kabuli (mRNA) Cicer arietinum

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELT-DQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGGNSP---APRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQIL 1734
            +FVEIDPTGRYGRY+EVLGKGAFK+VYRAFD+LEGIEVAWNQVK+ D   +S DLDRLYSEVHLLKTLKHK+IIKFY SW+D ++  IN ITE+FTSG LRQYRKKHK VDLRALKKWSRQILEGL YLHSH PPVIHRDLKCDN+F+NGNQGEVKIGDLGLAAIL +A SAHSVIGTPEFMAPELYEE+YN LVDIYAFGMCLLELVT EYPY EC NAAQIY+KVTSGIKPA+L  VTDP+V+AFIEKCI++ S RL AK LL DPFL+                    N +N   I +   ++ V      TVEGQR+D+NTIFLKLRI DS G IRNIHFPFNI  DTS SVA EMVEEL+LT DQD+STIAK ID+EI  HIP W PS    ++S             A      SP +L L+  PSGRK+WS SPK   G+S    APR  S LS                       +A  P +                  +E+ V     +E + ++  K       QREE++E++R  +  V++FL EF PEIC++ L
Sbjct:   11 EFVEIDPTGRYGRYKEVLGKGAFKEVYRAFDQLEGIEVAWNQVKLDDKFCSSEDLDRLYSEVHLLKTLKHKSIIKFYTSWIDHQHMTINLITEVFTSGNLRQYRKKHKCVDLRALKKWSRQILEGLVYLHSHDPPVIHRDLKCDNIFINGNQGEVKIGDLGLAAILHRARSAHSVIGTPEFMAPELYEEDYNVLVDIYAFGMCLLELVTFEYPYSECTNAAQIYRKVTSGIKPAALLNVTDPQVRAFIEKCIAKVSQRLSAKELLDDPFLK------CYKENTENVSSHKENGYNGNGIVDKLSDSEVGL---LTVEGQRKDLNTIFLKLRITDSKGQIRNIHFPFNIETDTSFSVAIEMVEELDLTDDQDISTIAKMIDTEIHSHIPDWTPSRLIGDDS-------------AVQKCLSSPETLHLDRFPSGRKFWS-SPKAGAGDSRSPFAPRSNSKLS-----------------------SAQGPIN------------------QEVGV----IVEKLESLLRK-------QREEIEEMQRDQERIVTEFLKEFPPEICEEAL 503          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFN----------------HQSIGESAKENS----VETSWE--------FTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDN----------NSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADS-PFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSIC 1743
            +F E+DPT RYGRY EVLGKGAFK VY+AFD+LEG+EVAWNQ+KV D++RN+ DL+RL SEV LLKTLKHKNIIKFYNSW+D KN NINFITE+FTSGTLRQYR KHK VD+RALKKWSRQIL GL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLA IL  A SAHS+IGTPEFMAPELY+EEYNELVDIYAFGMCLLELVT EYPY EC+NAAQIYKKV+ G KP+SLAK+ DPEV+ FIEKCI++AS RL A+ LLMDPFL+                     + N                 +  G  A+E+     + ++ +         TVE Q +D+NTIFLKLRIADS+GH +NIHFPF+I ADTSISVA+EMV +L+LTDQDV+ IA+ ID+EI+ HIP W   E+ +N          +S E   +T E + E     N + +    E LPSG KYWSDSP+            S +   +  N   GIL  N  +        S      S+I    +   G +S+      +D E  + + ++ +L  LL  Q+EEL+ L+RKHK  +   L     E  ++ L+ C
Sbjct:   17 EFAEVDPTARYGRYTEVLGKGAFKTVYKAFDQLEGLEVAWNQIKVGDILRNNDDLERLRSEVRLLKTLKHKNIIKFYNSWLDKKNNNINFITEVFTSGTLRQYRIKHKKVDVRALKKWSRQILSGLVYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLATILDNARSAHSIIGTPEFMAPELYDEEYNELVDIYAFGMCLLELVTFEYPYCECSNAAQIYKKVSDGEKPSSLAKIEDPEVRFFIEKCIAKASQRLSAQELLMDPFLRDDGEKIFYPLQSNTKASDGAGSSNSSMGYKYDRDASSMAIREHTGSFAEEHPSDRYIHSTMDPQAAAGRIITVESQMKDLNTIFLKLRIADSTGHAQNIHFPFDIEADTSISVATEMVVQLDLTDQDVTAIAEMIDAEIRAHIPDWALEESVENQGDERAHSETDSSEADDETSELRNEP----NATHNGFVQEHLPSGHKYWSDSPR-----RNIEMSHSAVEPHIGGNMPNGILKKNDTDDTVSNLGTSVDLPNPSMI----DRKSGVASVSTSPQSFDDEHIEAD-VSERLVNLLAQQQEELNVLRRKHKADIEVILKGVPEEHREETLTRC 608          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQS----------IGESAKENS-VETSW--------------------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNP 1215
            ++ E+DPTGRYGRY +VLGKGA K VYRAFDE +G+EVAWNQVK+ D +++  DL+RLY E+HLLKTLKH+NI+KFY SWVD    NINFITE+FTSGTLRQYR+KH  V++ A+K W RQIL GL YLHSH PP+IHRDLKCDN+FVNGNQGEVKIGDLGLAAIL+++ + H V GTPEFMAPE+YEEEYNELVDIY+FGMC+LE+VT EYPY EC +  QIYKKV SG KP +L KV DP V+ F+EKC++ AS RL A+ LL DPFLQ                      +   +          + ES  E++  E  W                          + T++G++ +  +IFL+LRIAD+ GH+RNI+FPF+I ADT++SVA+EMV EL++TD +V+ IA+ ID E+   +P W P
Sbjct:   16 EYAEVDPTGRYGRYNDVLGKGASKTVYRAFDEYQGMEVAWNQVKLHDFLQSPEDLERLYCEIHLLKTLKHRNIMKFYTSWVDVSRRNINFITEMFTSGTLRQYRQKHMRVNIWAVKHWCRQILSGLLYLHSHDPPIIHRDLKCDNIFVNGNQGEVKIGDLGLAAILRKSHAVHCV-GTPEFMAPEVYEEEYNELVDIYSFGMCVLEMVTFEYPYSECTHPVQIYKKVISGTKPEALYKVKDPMVRQFVEKCLATASRRLSARELLKDPFLQVDDLVFCPGDGDYSLMNYLRQPYLEHAYSNVSMMSNGLSESIDEDTPTEDRWDCEDDDIKADGIDLFNGHEDEPLGNVDITIKGRKSEDGSIFLRLRIADNDGHVRNIYFPFDIEADTALSVATEMVAELDITDHEVTRIAEMIDGEVSALVPDWRP 442          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQS----------IGESAKENS-VETSW--------------------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNP 1215
            ++ E+DPTGRYGRY +VLGKGA K VYRAFDE +G+EVAWNQVK+ D +++  DL+RLY E+HLLKTLKH+NI+KFY SWVD    NINFITE+FTSGTLRQYR+KH  V++ A+K W RQIL GL YLHSH PP+IHRDLKCDN+FVNGNQGEVKIGDLGLAAIL+++ + H V GTPEFMAPE+YEEEYNELVDIY+FGMC+LE+VT EYPY EC +  QIYKKV SG KP +L KV DP V+ F+EKC++ AS RL A+ LL DPFLQ                      +   +          + ES  E++  E  W                          + T++G++ +  +IFL+LRIAD+ GH+RNI+FPF+I ADT++SVA+EMV EL++TD +V+ IA+ ID E+   +P W P
Sbjct:   16 EYAEVDPTGRYGRYNDVLGKGASKTVYRAFDEYQGMEVAWNQVKLHDFLQSPEDLERLYCEIHLLKTLKHRNIMKFYTSWVDVSRRNINFITEMFTSGTLRQYRQKHMRVNIWAVKHWCRQILSGLLYLHSHDPPIIHRDLKCDNIFVNGNQGEVKIGDLGLAAILRKSHAVHCV-GTPEFMAPEVYEEEYNELVDIYSFGMCVLEMVTFEYPYSECTHPVQIYKKVISGTKPEALYKVKDPMVRQFVEKCLATASRRLSARELLKDPFLQVDDLVFCPGDGDYSLMNYLRQPYLEHAYSNVSMMSNGLSESIDEDTPTEDRWDCEDDDIKADGIDLFNGHEDEPLGNVDITIKGRKSEDGSIFLRLRIADNDGHVRNIYFPFDIEADTALSVATEMVAELDITDHEVTRIAEMIDGEVSALVPDWRP 442          

Query:   46 FVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNN--FNHQSIGESAKENSVETSW---------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSW--------NPSETPDNNSFEFSGQ 1257
            FVEIDP+GRYGRY E+LGKGA K VYRAFDE EGIEVAWNQVK+ +  RN  +L++ + E+HLLKTL H+NI+KFY SWVD  N +INF+TE+FTSGTLRQYR +H+ V++RA+K+W +QIL+GL YLHS  PP+IHRDLKCDN+F+NGNQGEVKIGDLGLAAIL++ S A   +GTPEFMAPE+Y+EEYNELVD+YAFGMC+LE+VT +YPY EC + AQIYKKVTSG KP +   V DPEV+ F+EKC++  + RL A  LL DPFLQ                          H  I +    +  E+S                + +++G+R   + IFL+LRI+D+ G IRNI+FPF    DT+ SVA EMV EL++T+QDV+ IA+ ID+EI   +P W        N +   +NN+  F G+
Sbjct:   14 FVEIDPSGRYGRYDEILGKGASKTVYRAFDEYEGIEVAWNQVKLRNFTRNPEELEKFFREIHLLKTLNHQNIMKFYTSWVDTNNLSINFVTELFTSGTLRQYRLRHRRVNIRAVKQWCKQILKGLLYLHSRSPPIIHRDLKCDNIFINGNQGEVKIGDLGLAAILRK-SHAVRCVGTPEFMAPEVYDEEYNELVDVYAFGMCVLEMVTFDYPYSECTHPAQIYKKVTSGKKPEAFYLVKDPEVREFVEKCLANVTCRLTALELLQDPFLQDDNMDGFVMRPIDYYNGYDETGVFLRHPLIDDPLYHDQFESSQICEIDLFANDDEDHVDISIKGKRNGDDGIFLRLRISDAEGRIRNIYFPFETAIDTAWSVAVEMVSELDITNQDVAKIAEMIDAEIAALVPDWKNDTESSQNVNNNKNNNTAGFCGE 441          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSI-------GESAKENSV--------------ETSWEFTVEGQRRDVNTIF-------------LKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPET-KTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGG--NSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRK 1671
            + +E+DPT RY RY+EV+GKGAFK VY+AFDE++GIEVAWNQV++ D++++   L+RLYSEV LLK+LKH NII+FYNSW+D KN+ +N ITE+FTSG+LR YRKKH+ V+++A+K W+RQIL GL YLH  +PP+IHRDLKCDN+F+NGN GEVKIGDLGLA +++QA +A SVIGTPEFMAPELY+E YNEL DIY+FGMC+LE+VT +YPY EC N+AQIYKKV+SGIKPASL++V DPEVK FIEKC+  AS+RL AK LL+DPFLQ                      F  + +          +K  S+              + S    +E +R      F             L LRI D +G +RNIHF F    DT+  V+SEMVE+LELTDQ+V+ IA+ ID  +   IP+W    T D+       Q   +   EA P   +                + D+ + V    NS  PR            +DE       A K  D+++    +E +      E    +  LEEI  +Y    ED+  IATK E  ++  +++L  +K K
Sbjct:   17 EVLEVDPTFRYIRYKEVIGKGAFKTVYKAFDEVDGIEVAWNQVRIDDVLQSPNCLERLYSEVRLLKSLKHNNIIRFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVNMKAVKNWARQILMGLRYLHGQEPPIIHRDLKCDNIFINGNHGEVKIGDLGLATVMEQA-NAKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFDYPYCECKNSAQIYKKVSSGIKPASLSRVKDPEVKQFIEKCLLPASERLSAKELLLDPFLQLNGLTMNNPLPLPDIVMPKEGAFGDRCLMSEGPPTTRPSKTLSIDLDEDSNLPIVTFSDNSGSRCIEVRRAKRGNFFVLKGEENDEQSVSLILRIVDENGRVRNIHFLFYQEGDTASKVSSEMVEQLELTDQNVTFIAELIDILLVNMIPTWKTDVTVDHLIHSQLNQNSRSHHNEAKPQKQE-------------ETVFHDTCELVSHSCNSDCPR------------SDEEDKQCVDATKGEDKSSIQEVEEATEPVSLEEEERLRQELEEIEAKYQ---EDMKEIATKREEAIMETKKKLSLMKLK 567          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFL------QXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEF----TVE------------------------------GQRRD-VNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWN 1212
            ++VE+DPTGRYGRY EVLGKG+ K VYR FDE +GIEVAWNQVK+ D +++  +L+RLY E+HLLKTLKHK+I+KFY SWVD  N NINF+TE+FTSGTLRQYR KHK V++RA+K W RQIL GL+YLH+H PPVIHRDLKCDN+F+NGNQGEVKIGDLGLAA LQ + +AH V GTPEFMAPE+Y+EEYN+LVDIY+FGMC+LE+VT +YPY EC++ AQIYK+V SG KP  L KV DPEV+ FIEKC++  S RL A  LL D FL                            +  H S G  +  N  +  W++    TVE                              G+RRD  + +FL+L+  +  G +RNI+FPF+I  DT+ISVA EMVEELE+ D+DV+ IA  ID EI   +P+W+
Sbjct:   14 EYVEVDPTGRYGRYNEVLGKGSSKTVYRGFDEYQGIEVAWNQVKLYDFLQSPQELERLYCEIHLLKTLKHKSIMKFYASWVDTDNRNINFVTEMFTSGTLRQYRLKHKRVNIRAVKNWCRQILRGLNYLHTHDPPVIHRDLKCDNIFINGNQGEVKIGDLGLAACLQHSHAAHCV-GTPEFMAPEVYKEEYNQLVDIYSFGMCVLEMVTFDYPYSECSHPAQIYKRVISGKKPDGLDKVKDPEVRGFIEKCLATVSLRLSACELLDDHFLCIDESDMRRVESEKGLIDEAGTPLRHSYHIPHYSNGYYSLYN--QNQWDYNGDETVESHEIDLLEFQNDDDEEEEDKRFGSVDISIKGKRRDNGDGLFLRLKTVNKEGCVRNIYFPFDIETDTAISVAREMVEELEMDDRDVTKIANMIDGEIASLVPNWS 441          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWE---------------------------------FTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDN 1233
            + +EIDPT RY RY+EV+GKGA K V++ FDE++GIEVAWNQV++ DL+++   L+RLYSEV LLK+LKHKNII+FYNSW+D KN+ +N ITE+FTSG+LRQYRKKH+ V+++A+K W+RQIL GL YLHS  PP+IHRD+KCDN+F+NGN GEVKIGDLGLA +++QA +A SVIGTPEFMAPELY+E YNEL DIY+FGMC+LE+VT EYPY EC N+AQIYKKV+SGIKPASL+KV DPEV  FIEKC+  AS+RL A+ LL+D FL                      +F  + +      N+   +                                   F ++G+  D N++ L LRI D +G +RNIHF F    DT+ +V+SEMVE+LELTD++V  IA+ ID  +   IP+W      D+
Sbjct:   17 EVLEIDPTCRYIRYKEVIGKGASKTVFKGFDEVDGIEVAWNQVRIDDLLQSPDCLERLYSEVRLLKSLKHKNIIRFYNSWIDDKNKTVNIITELFTSGSLRQYRKKHRKVNMKAVKCWARQILTGLKYLHSQDPPIIHRDIKCDNIFINGNHGEVKIGDLGLATVMEQA-NAKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFEYPYCECRNSAQIYKKVSSGIKPASLSKVKDPEVMKFIEKCLLPASERLSAEELLLDSFLNVNGLVMNNPLPLPDIVMPKEGSFGERCLMSEGPPNARNRTMSMNLDEDNNLPIVISSNNSGTNCIEVRRAKRGNFFVLKGEENDENSVSLILRIVDENGRVRNIHFLFFQEGDTASNVSSEMVEQLELTDKNVKFIAELIDVLLVNLIPNWKTDVAVDH 445          

Query:   40 IDFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVET-SWEFTVEGQ-RRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSET 1224
            I +VE DP+GRYGR+REVLGKGA K VY+AFD++ G+EVAWNQVK++++ R+   L RLYSEVHLLK L H++II++  SW+D      NFITE+FTSGTLR+YR+K++ VD+RA+K W+RQIL GL+YLH H PPVIHRDLKCDN+FVNG+ G+VKIGDLGLAAIL+ + +AHSVIGTPEFMAPELYEE+YNELVDIY+FGMC+LE++T EYPY EC N AQIYKKVTSG  P S   +   E + F+ KC+   S RLPAK LL DPFL                     N   + ++ E     +  T + + ++ G+   + +TIFL+++I D  GH+RNI FPFNI +DT + VA EMV+ELE+TD D   IA  I++EI   +P+W  +++
Sbjct:   13 IAYVETDPSGRYGRFREVLGKGAMKTVYKAFDQVLGMEVAWNQVKLNEVFRSPEPLQRLYSEVHLLKNLNHESIIRYCTSWIDVNRRTFNFITELFTSGTLREYRRKYQKVDIRAIKSWARQILNGLAYLHGHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLAAILRGSQNAHSVIGTPEFMAPELYEEDYNELVDIYSFGMCVLEMLTGEYPYSECTNPAQIYKKVTSGKLPDSFHLIQHTEAQRFVGKCLETVSRRLPAKELLADPFLAATDERDLAPLFRLPQQLAIQNLAANGTVVEHLPSTTDPTRTTDMSITGKMNSEDHTIFLQVQILDGDGHMRNIQFPFNILSDTPLEVALEMVKELEITDWDPLEIAAMIENEISLLVPNWRANDS 409          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXN--NFNHQSIGESAKENSVETS-----W-------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLET--------LLVMQREELDELKRK 1671
            DF E DP+GRY RY +VLG+GAFK VY+AFDE++GIEVAWN V + D+++    L+RLYSEVHLLK LKH+NIIK + SWVD KN+ IN ITE+FTSG+LR YRKKH+ VD +A+K W+RQIL+GL+YLHS  PPVIHRDLKCDN+FVNGN GEVKIGDLGLA +LQQ  +A SVIGTPEFMAPELYEEEYNELVDIY+FGMC+LE+VT EYPY EC N AQIYKKVTS IKP SL KV DP+V+ FIEKC+  AS R  A  L  DPFL                           H  +     EN   +S     W             EF + G+R D  T  + LRIAD SG  R +HF F + +DT+ ++A EMVEEL LT Q+V  IA  ID  I   + S   S   + NS   + +  E   + +    D  +        +G+   SD                +  Y    +A++G     +A  E  R A+S       +S Y ++    S++  +S+  +   ED+ T    +E+        LL ++ + ++  KRK
Sbjct:   18 DFAEKDPSGRYIRYDDVLGRGAFKTVYKAFDEVDGIEVAWNLVSIEDVMQMPGQLERLYSEVHLLKALKHENIIKLFYSWVDEKNKTINMITELFTSGSLRVYRKKHRKVDPKAIKNWARQILKGLNYLHSQNPPVIHRDLKCDNIFVNGNTGEVKIGDLGLATVLQQ-PTARSVIGTPEFMAPELYEEEYNELVDIYSFGMCMLEMVTCEYPYNECRNQAQIYKKVTSNIKPQSLGKVDDPQVRQFIEKCLLPASSRPTALELSKDPFLARDGGKDSALLASSSTSSKYVRPPQLEHLPMDVDHNENKSVSSNEDYPWSQTIELQRIAENKEFRLRGERSDDVTASMVLRIADPSGKCRIVHFAFYLESDTATAIAEEMVEELHLTSQEVVVIADMIDDFIM-QLLSDRTSSHHNQNSPRLTHEDHEAANQQTVNSKDEEA--------AGQSMKSD---------------ISADYYFPYSANDG-----NAAMEAGRDAES-------MSSYLDSCSMMSTIYNLSISDNDYPEDLKTELNLIESQFNQSFQDLLKLKEDAIENAKRK 551          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRY-DSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            +FVEIDPT RYGRY+E+LGKGAFKKVYRAFDELEGIEVAWNQVKVSDL+RNS DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA+SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPY+EC NAAQIYKKV SGIKPASLAKV DPEVKAFIEKC +  S+RLPAKALLMDPFLQ                    NNF++QSIG+SA +NS ET  EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPF+I ADTSISVASEMVEELELTDQDVSTIA TIDSEI+YHIP+WNPSET DN+S + SG T ET  EASP+GN+SP SLALEILPSGRKYWSDSPKGVGGNSP    ASNLSYE DV A+EG LFANS  KECD TADSPF+E+SI SD SEATGG SS EEIS    DSE EDIN IATKLETLLVMQR+ELDELKRKHKLAVSDFL+EFSPEI  Q+L++CN +MPD EM
Sbjct:   15 EFVEIDPTARYGRYKEILGKGAFKKVYRAFDELEGIEVAWNQVKVSDLLRNSEDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHNPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQATSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYVECTNAAQIYKKVISGIKPASLAKVNDPEVKAFIEKCTAHVSERLPAKALLMDPFLQSDWDGDSVGRSSRSRTQHSGNNFDNQSIGKSANDNSAETGREFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFDIEADTSISVASEMVEELELTDQDVSTIAMTIDSEIRYHIPNWNPSETLDNSSCQESGHTLETMPEASPMGNESPGSLALEILPSGRKYWSDSPKGVGGNSPCLHAASNLSYEGDVIAEEGSLFANSVGKECDGTADSPFNEKSITSDCSEATGGMSSQEEISASLKDSETEDINKIATKLETLLVMQRDELDELKRKHKLAVSDFLNEFSPEISLQVLNMCNLQMPDGEM 591          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRY-DSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            +F EIDPTGRYGRY+E+LGKGAFKKVYRAFDELEGIEVAWNQVKVSDL+RNS DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA+SAHSVIGTPEFMAP LYEEEYNELVDIYAFGMCLLELVTVEYPY+ECANAAQIYKKVTSGIKPASLAKV DPEVKAFIEKC +  ++RLPAKALLMDPFLQ                    NNF++QSIG+SA +NS ET  EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPF+I ADTSISVASEMVEELELTDQDVSTIA TIDSEI+YHIP+WNP ET DN+S + SG T ET  EASP+GN+SP SLALEILPSGRKYWSDSPKGVGGNSP    ASNLSYE DV A+EG LFANS  KECD TADSP +E+SI SD SEATGG SS EEISV   DSE EDIN IATKLETLLVMQ++ELDELKRKHKLAVSDFL+EFSPEI  Q+L++CN +MPD EM
Sbjct:   15 EFAEIDPTGRYGRYKEILGKGAFKKVYRAFDELEGIEVAWNQVKVSDLLRNSEDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHNPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQATSAHSVIGTPEFMAPXLYEEEYNELVDIYAFGMCLLELVTVEYPYVECANAAQIYKKVTSGIKPASLAKVNDPEVKAFIEKCTAHVTERLPAKALLMDPFLQSDWDGDSVGRSSRSRTQQSGNNFDNQSIGKSANDNSTETGREFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFDIEADTSISVASEMVEELELTDQDVSTIAMTIDSEIRYHIPNWNPIETLDNSSCQDSGHTLETMPEASPMGNESPGSLALEILPSGRKYWSDSPKGVGGNSPCLHAASNLSYEGDVIAEEGSLFANSTGKECDGTADSPSNEKSITSDCSEATGGMSSQEEISVSLKDSETEDINKIATKLETLLVMQQDELDELKRKHKLAVSDFLNEFSPEISLQVLNMCNLQMPDGEM 591          

Query:   40 IDFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKEN----------SVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGND---SPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFAN-----------SAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRY-DSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            I+FVE+DPTGRYGRY+EVLGKGAFKKVYRAFDELEGIEVAWNQVKV+DL+RNS DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYRKKHKHVDLRA+KKWSRQILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA+SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIEC NAAQIYKKVTSGIKPASLAKV D EVKAFIEKCI+  S+RL AK LLMDPFLQ                    ++ ++ S+G+S++            +VE S EFTVEGQRRD +TIFLKLRIADSSG+IRNIHFPF+I ADTSISVA EMVEELELTDQDV+TIA+ IDSEI+YHIPSWN SETP + + + S  T ET+ E SP+ ND   SP SLALEILPSGR+YWSDSP+GVGGNSP+    S LS E  VNA+EG L  N           +AE+ECD  ADSP  E SI S    AT  KSS +EIS    DSE E IN I TKLE LLV QREELDELKRKHKLAVSD L E  PE+CQ++L++CN +MPD EM
Sbjct:   15 IEFVEVDPTGRYGRYKEVLGKGAFKKVYRAFDELEGIEVAWNQVKVADLLRNSEDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRKKHKHVDLRAVKKWSRQILEGLLYLHSHNPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQANSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECTNAAQIYKKVTSGIKPASLAKVADLEVKAFIEKCIADVSERLSAKDLLMDPFLQ--------------------SDNDNDSVGQSSRSQTHHSGNSSHIAVEPSREFTVEGQRRDNHTIFLKLRIADSSGNIRNIHFPFDIEADTSISVAGEMVEELELTDQDVTTIARMIDSEIRYHIPSWNFSETPLDINHQDSSCTSETRPETSPMKNDSIASPGSLALEILPSGRRYWSDSPRGVGGNSPSQHFTSILSNETGVNAEEGNLITNGDISANDCVDGTAERECDEIADSPSSEISITSG---ATSEKSSQKEISRSLKDSETEYINQITTKLENLLVKQREELDELKRKHKLAVSDLLMEIPPEMCQKVLNVCNLQMPDGEM 593          

Query:   40 IDFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDS---PSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFAN-----------SAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            I+FVEIDPTGRYGRY+EVLGKGAFKKVYRAFDELEGIEVAWNQVKV+DL+RNS DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYRKKHKHVDLRA+KKWSRQILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA+SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIEC NAAQIYKKVTSGIKPASLAKV D EVKAFIEKCI+  S+RL AK LL+DPFLQ                    NN ++Q+I   A++NSVETS EFTVEGQR+D +TIFLKLRIADSSG+IRNIHFPF+  ADTSISVASEMVEELELTDQDV+TIA  IDSEI+YHIPSWN SETP + + + S  T ET+ EASP+  DS   P SLALEILPSGRKYWSDSP+G GGNSP+    S LS E  VN++E    AN           + E+ECD  ADSP  E+                        SE+E IN I TKLE LLV QREELDELKRKHKLAVSD L E  PE+CQ++L+ICN +MPDSEM
Sbjct:   15 IEFVEIDPTGRYGRYKEVLGKGAFKKVYRAFDELEGIEVAWNQVKVADLLRNSDDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRKKHKHVDLRAVKKWSRQILEGLLYLHSHNPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQANSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECTNAAQIYKKVTSGIKPASLAKVADLEVKAFIEKCIADVSERLSAKDLLIDPFLQSDYDNDSVGRSSRSQTHHSGNNSHNQAI---AEDNSVETSREFTVEGQRKDNHTIFLKLRIADSSGNIRNIHFPFDTEADTSISVASEMVEELELTDQDVTTIAGMIDSEIRYHIPSWNFSETPVDFNHQDSSYTSETRPEASPMKIDSVVAPGSLALEILPSGRKYWSDSPRGFGGNSPSRHMTSILSNEAGVNSEEDNPTANGGISADDCVDGTIEQECDEIADSPSSEK------------------------SEMEYINQITTKLENLLVKQREELDELKRKHKLAVSDLLMEIPPEMCQKVLNICNLQMPDSEM 578          

Query:   40 IDFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGND---SPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFAN-----------SAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRY-DSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            I+FVE+DPTGRYGRY+EVLGKGAFKKVYRAFDELEGIEVAWNQVKV+DL+RNS DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYRKKHKHVDLRA+KKWSRQILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA+SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIEC NAAQIYKKVTSGIKPASLAKV D EVKAFIEKCI+  S+RL AK LLMDPFLQ                    ++ ++ S+G S+   +VE S EFTVE                   G+IRNIHFPF+I ADTSISVA EMVEELELTDQDV+TIA+ IDSEI+YHIPSWN SETP + + + S  T ET+ E SP+ ND   SP SLALEILPSGR+YWSDSP+GVGGNSP+    S LS E  VNA+EG L  N           +AE+ECD  ADSP  E SI S    AT  KSS +EIS    DSE E IN I TKLE LLV QREELDELKRKHKLAVSD L E  PE+CQ++L++CN +MPD EM
Sbjct:   15 IEFVEVDPTGRYGRYKEVLGKGAFKKVYRAFDELEGIEVAWNQVKVADLLRNSEDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRKKHKHVDLRAVKKWSRQILEGLLYLHSHNPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQANSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECTNAAQIYKKVTSGIKPASLAKVADLEVKAFIEKCIADVSERLSAKDLLMDPFLQ--------------------SDNDNDSVGNSS-HIAVEPSREFTVE-------------------GNIRNIHFPFDIEADTSISVAGEMVEELELTDQDVTTIARMIDSEIRYHIPSWNFSETPLDINHQDSSCTSETRPETSPMKNDSIASPGSLALEILPSGRRYWSDSPRGVGGNSPSQHFTSILSNETGVNAEEGNLITNGDISANDCVDGTAERECDEIADSPSSEISITSG---ATSEKSSQKEISRSLKDSETEYINQITTKLENLLVKQREELDELKRKHKLAVSDLLMEIPPEMCQKVLNVCNLQMPDGEM 563          

Query:   40 IDFVEIDPTGRYGRYREVLGKGAFKKV--YRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDS---PSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFAN-----------SAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            I+FVEIDPTGRYGRY+EVLGKGAFKK+  YRAFDELEGIEVAWNQVKV+DL+RNS DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYRKKHKHVDLRA+KKWSRQILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA+SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIEC NAAQIYKKVTSGIKPASLAKV D EVKAFIEKCI+  S+RL AK LL+DPFLQ                    NN ++Q+I   A++NSVETS EFTVE                   G+IRNIHFPF+  ADTSISVASEMVEELELTDQDV+TIA  IDSEI+YHIPSWN SETP + + + S  T ET+ EASP+  DS   P SLALEILPSGRKYWSDSP+G GGNSP+    S LS E  VN++E    AN           + E+ECD  ADSP  E+                        SE+E IN I TKLE LLV QREELDELKRKHKLAVSD L E  PE+CQ++L+ICN +MPDSEM
Sbjct:   15 IEFVEIDPTGRYGRYKEVLGKGAFKKILIYRAFDELEGIEVAWNQVKVADLLRNSDDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRKKHKHVDLRAVKKWSRQILEGLLYLHSHNPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQANSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECTNAAQIYKKVTSGIKPASLAKVADLEVKAFIEKCIADVSERLSAKDLLIDPFLQSDYDNDSVGRSSRSQTHHSGNNSHNQAI---AEDNSVETSREFTVE-------------------GNIRNIHFPFDTEADTSISVASEMVEELELTDQDVTTIAGMIDSEIRYHIPSWNFSETPVDFNHQDSSYTSETRPEASPMKIDSVVAPGSLALEILPSGRKYWSDSPRGFGGNSPSRHMTSILSNEAGVNSEEDNPTANGGISADDCVDGTIEQECDEIADSPSSEK------------------------SEMEYINQITTKLENLLVKQREELDELKRKHKLAVSDLLMEIPPEMCQKVLNICNLQMPDSEM 561          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSW-NPSETPDNNSFEFSGQTPETKTEASPIGND---SPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            +FVEIDPTGRYGRY+EVLG+GAFKKVYRAFDE EGIEVAWNQVKV+DL+RNSVDL+RLYSEVHLL TLKHKNIIKFYNSW+D KNENINFITEIFTSGTLRQYR+KHKHV LRALKKWSRQILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPY+EC NAAQIYKKVTSGIKPASLAKV DP VKAFIEKC ++ SDRLPAK LLMDPFLQ                     + +   + E AK++S E   +FTV+GQR+D+NTIFLKLRIADS+GHIRNIHFPF++  DT+I+VASEMVEEL+LTDQDVSTIA  IDSEI+ HIP W + + +P+N   E S    ETK ++SP+ N+   SP SL LE LPSGRKYWSDSPK V GNSP+    SNLS       +  +   N+A       A+S  D+     D + A  G +  +++    +     +  IA KL+ LLVMQ++EL+ELKRKHK+A+ D L+E SPEI Q +L+IC  ++P  EM
Sbjct:   17 EFVEIDPTGRYGRYKEVLGRGAFKKVYRAFDEFEGIEVAWNQVKVADLLRNSVDLERLYSEVHLLNTLKHKNIIKFYNSWIDTKNENINFITEIFTSGTLRQYRQKHKHVGLRALKKWSRQILEGLLYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQARSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYVECTNAAQIYKKVTSGIKPASLAKVKDPAVKAFIEKCTAKVSDRLPAKELLMDPFLQSDEENESVGHSFRPKAHSSGGSSDQIDVNEIAKDSSAEPIRDFTVQGQRKDINTIFLKLRIADSTGHIRNIHFPFDVEVDTAIAVASEMVEELDLTDQDVSTIAAMIDSEIRSHIPGWASHNVSPENLVAEDSEPPFETKDDSSPLSNESIPSPGSLVLERLPSGRKYWSDSPKDVDGNSPSKLGRSNLSCH-----EPSLSCPNAARSNGQLEAESMSDD-----DDNSAKHGSNRSDDLQYA-NRNSTSVKIIAEKLDKLLVMQQQELEELKRKHKVAILDLLNEVSPEIRQDVLNICKLKIPVHEM 585          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESA--KENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSE-TPDNNSFEFSGQTPETKTEASPIGND---SPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRY-DSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDSEM 1770
            +FVEIDP+GRYGRY+EVLG+GAFKKVYRAFDELEGIEVAWNQVKV+DL+RNSVDL+RL+SEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLR+YR+KHKHVDLRALKKWS+QILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPY+EC+NAAQIYKKVTSGIKPASLAKV DP VKAFIEKCI++ SDRLPAK LLMDPFL+                       +   + ESA  K+++ E+S +F+V+GQR+D+NTIFLKLRIADS+GH RNIHFPF++  DT+I+VASEMVEEL++TDQDVSTIA  IDSEI+ HIP W+ +  +P+N + E S    ETK ++SP+ N+   SP SL LE L SG KYW DSPK V G+SP+    SNLS+     +       N A+      A S       +SD  + +G   S    ++ + +     +  IA KLE LLVMQ++EL+E+KRKHK+A+SD L+E SPEIC +IL+IC  ++P  EM
Sbjct:   17 EFVEIDPSGRYGRYKEVLGRGAFKKVYRAFDELEGIEVAWNQVKVADLLRNSVDLERLFSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRKYRQKHKHVDLRALKKWSKQILEGLLYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQARSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYVECSNAAQIYKKVTSGIKPASLAKVKDPAVKAFIEKCIAKVSDRLPAKELLMDPFLRSDEENVSGGCSLRPKAHSSGGISDQLDVNESAKDKDSAAESSRDFSVQGQRKDINTIFLKLRIADSTGHFRNIHFPFDVKVDTAIAVASEMVEELDVTDQDVSTIAAMIDSEIRSHIPDWDSNNVSPENLAAEDSEPPSETKDDSSPLSNESSLSPGSLVLEKLSSGHKYWRDSPKDVDGDSPSKLGCSNLSFHRSCPSS-----PNDAQSPGQLEAGS-------MSDGDDGSGKNGSHRSDNLHFANRNSTSVKIIAEKLENLLVMQQQELEEVKRKHKVAISDLLNEVSPEICVEILNICKLKIPGYEM 587          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFE--FSGQTPETKTEASPIGND---SPSSLALEILPSGRKYWSDSPKGVGGNSPAPRCASN-LSYEVDVNADEG----------------ILFANSAE-KECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPD 1761
            +FVEIDPTGRYGRY+EVLG+GAFKKVYRAFDELEGIEVAWNQVKV++LVRN  DL+RLYSEVHLLKTLKHKNIIKFYNSWVD KNENINFITEIFTSGTLRQYR+KHKHVDLRALKKWSRQILEGLSYLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAILQQA SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVT +YPY EC NAAQI+KKVTSGIKPASLAKVTDP VKAFIEKCI+R SDRL AK LLMDPFL+                     + +    G+ A + S+E S +FTV+GQ +DVNTIFLKLRIADS+GHIRNIHFPF+I  DT+I+VASEMVEEL+LTDQDVSTIA  IDSEIQ HIP W P +   +N        +T     + SP+ N+   S  SLALE LPSGRKYWS SPK VGG+SP+    SN  SYE  +++ +                  L  NS E +E      S   +R+  S       G+ + +   +  D E  D+N +  KLE LLV Q++ELD+LKR+H+ A+SD L+E SPEI +Q+LS C   +PD
Sbjct:   17 EFVEIDPTGRYGRYKEVLGRGAFKKVYRAFDELEGIEVAWNQVKVAELVRNFDDLERLYSEVHLLKTLKHKNIIKFYNSWVDTKNENINFITEIFTSGTLRQYRRKHKHVDLRALKKWSRQILEGLSYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILQQARSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTFDYPYAECINAAQIFKKVTSGIKPASLAKVTDPSVKAFIEKCIARVSDRLSAKELLMDPFLRPDEENEIIGHSLRQKSHHPGGSPDQTISGKGAGDPSLEKSRDFTVQGQMKDVNTIFLKLRIADSTGHIRNIHFPFDIEVDTAIAVASEMVEELDLTDQDVSTIAAIIDSEIQSHIPDWTPRKLSSDNMCPEVMDSETASEIKDDSPLTNESTHSSGSLALERLPSGRKYWS-SPKAVGGSSPSKLGHSNSSSYEPSLSSHQAGNGPNVSCSLEQFEAENLSQNSREDEEASWPVGSQSRDRNSASVDQGLETGEQASDSSKISMDVE-PDVNILVQKLENLLVKQQKELDDLKRRHEEAISDLLNEVSPEISRQVLSFCKLSLPD 610          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSET--PDNNSFEFSGQ---TPETKTEASPIGNDSPSS---LALEILPSGRKYWSDSPKGVGGNSPAPRCASNLSYEVDVNADEGILF---------------ANSA------------------EKECDRTADSPFDERSIISDYSEATGGKSSLE---EISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSICNPEMPDS 1764
            +FVEIDPTGRYGRY+EVLGKGAFKKVYRAFDELEGIEVAWNQVKV+DL+RNS + +RLYSEVHLLKTLKHKNIIKFY SWVD +NENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLAAIL+QA SAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVT EYPY+ECANAAQIYKKVTSGIKPASLAKV DP V+AFI+KCI+  SDRL AK LL DPFLQ                    ++ +H + G S+K +  E+S +F V+GQRRDVNTIFLKLRIADS GHIRNIHFPF+IGADT+ISVA EMVEEL+LTDQDVSTIA  IDSEI+  I  W PS     DN S E +      PE++ +A P+ N+S +S   L LE LPSGR+YWSDSPK VGGNSP     SNLS +VD    EG                   N+A                  EKE   +A++ F +++ ++   E  GG  +        +  ++E+ D   I  KL+ L V Q++ELDELKRKH+LA+ D + E  P+I  ++ S+CN ++  S
Sbjct:   17 EFVEIDPTGRYGRYKEVLGKGAFKKVYRAFDELEGIEVAWNQVKVADLLRNSEEFERLYSEVHLLKTLKHKNIIKFYISWVDTRNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLLYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILRQARSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTFEYPYVECANAAQIYKKVTSGIKPASLAKVKDPRVRAFIDKCIANVSDRLSAKELLRDPFLQSDEENGSVGRSLQPHPHHSGSH-DHFNTGTSSKVSLPESSRDFKVQGQRRDVNTIFLKLRIADSKGHIRNIHFPFDIGADTAISVAGEMVEELDLTDQDVSTIAAMIDSEIRSIISDWPPSREVFGDNLSTEVAISDICPPESEGDALPLMNESATSSCGLVLERLPSGRRYWSDSPKAVGGNSPIRPAFSNLSSQVDSVTTEGRFSELNEQSLASPRDGDKLNTAASLDKREDERVCGDDDVEEKEASISAETQFSDQNDVA--VELLGGYRAPSWGGNCKILRETELGDAKVIVEKLKHLFVKQQKELDELKRKHELAILDLVKELPPDIRNKVSSLCNLKISGS 631          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELT-DQDVSTIAKTIDSEIQYHIPSWNPSETPDNNSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPKGVGGNSP---APRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQIL 1734
            +FVEIDPTGRYGRY+EVLGKGAFK+VYRAFD+LEGIEVAWNQVK+ D   +S DLDRLYSEVHLLKTLKHK+IIKFY SW+D ++  IN ITE+FTSG LRQYRKKHK VDLRALKKWSRQILEGL YLHSH PPVIHRDLKCDN+F+NGNQGEVKIGDLGLAAIL +A SAHSVIGTPEFMAPELYEE+YN LVDIYAFGMCLLELVT EYPY EC NAAQIY+KVTSGIKPA+L  VTDP+V+AFIEKCI++ S RL AK LL DPFL+          ++ + + H  N +N   I +   ++ V      TVEGQR+D+NTIFLKLRI DS G IRNIHFPFNI  DTS SVA EMVEEL+LT DQD+STIAK ID+EI  HIP W PS    ++S             A      SP +L L+  PSGRK+WS SPK   G+S    APR  S LS                       +A  P +                             +++  I  KLE+LL  QREE++E++R  +  V++FL EF PEIC++ L
Sbjct:   11 EFVEIDPTGRYGRYKEVLGKGAFKEVYRAFDQLEGIEVAWNQVKLDDKFCSSEDLDRLYSEVHLLKTLKHKSIIKFYTSWIDHQHMTINLITEVFTSGNLRQYRKKHKCVDLRALKKWSRQILEGLVYLHSHDPPVIHRDLKCDNIFINGNQGEVKIGDLGLAAILHRARSAHSVIGTPEFMAPELYEEDYNVLVDIYAFGMCLLELVTFEYPYSECTNAAQIYRKVTSGIKPAALLNVTDPQVRAFIEKCIAKVSQRLSAKELLDDPFLK------CYKENTENVSSHKENGYNGNGIVDKLSDSEVGL---LTVEGQRKDLNTIFLKLRITDSKGQIRNIHFPFNIETDTSFSVAIEMVEELDLTDDQDISTIAKMIDTEIHSHIPDWTPSRLIGDDS-------------AVQKCLSSPETLHLDRFPSGRKFWS-SPKAGAGDSRSPFAPRSNSKLS-----------------------SAQGPIN-----------------------------QEVGVIVEKLESLLRKQREEIEEMQRDQERIVTEFLKEFPPEICEEAL 503          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFN----------------HQSIGESAKENS----VETSWE--------FTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDN----------NSFEFSGQTPETKTEASPIGNDSPSSLALEILPSGRKYWSDSPK------------GVGGNSPAPRCASNLSYEVDVNADEGILFANSAEKECDRTADSPFDERSIISDYSEATGGKSSLEEISVRYDSEIEDINTIATKLETLLVMQREELDELKRKHKLAVSDFLSEFSPEICQQILSIC 1743
            +F E+DPT RYGRY EVLGKGAFK VY+AFD+LEG+EVAWNQ+KV D++RN+ DL+RL SEV LLKTLKHKNIIKFYNSW+D KN NINFITE+FTSGTLRQYR KHK VD+RALKKWSRQIL GL YLHSH PPVIHRDLKCDN+FVNGNQGEVKIGDLGLA IL  A SAHS+IGTPEFMAPELY+EEYNELVDIYAFGMCLLELVT EYPY EC+NAAQIYKKV+ G KP+SLAK+ DPEV+ FIEKCI++AS RL A+ LLMDPFL+ D +       S + A     + N                 +  G  A+E+     + ++ +         TVE Q +D+NTIFLKLRIADS+GH +NIHFPF+I ADTSISVA+EMV +L+LTDQDV+ IA+ ID+EI+ HIP W   E+ +N          +S E   +T E + E +   N        E LPSG KYWSDSP+             +GGN P      N + +   N    +   N           S  D +S ++  S +     S ++  +  D        ++ +L  LL  Q+EEL+ L+RKHK  +   L     E  ++ L+ C
Sbjct:   17 EFAEVDPTARYGRYTEVLGKGAFKTVYKAFDQLEGLEVAWNQIKVGDILRNNDDLERLRSEVRLLKTLKHKNIIKFYNSWLDKKNNNINFITEVFTSGTLRQYRIKHKKVDVRALKKWSRQILSGLVYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLATILDNARSAHSIIGTPEFMAPELYDEEYNELVDIYAFGMCLLELVTFEYPYCECSNAAQIYKKVSDGEKPSSLAKIEDPEVRFFIEKCIAKASQRLSAQELLMDPFLRDDGEKIFYPLQSNTKASDGAGSSNSSMGYKYDRDASSMAIREHTGSFAEEHPSDRYIHSTMDPQAAAGRIITVESQMKDLNTIFLKLRIADSTGHAQNIHFPFDIEADTSISVATEMVVQLDLTDQDVTAIAEMIDAEIRAHIPDWALEESVENQGDERAHSETDSSEADDETSELRNEPNATHN----GFVQEHLPSGHKYWSDSPRRNIEMSHSAVEPHIGGNMPNGILKKNDTDDTVSNLGTSVDLPNP----------SMIDRKSGVASVSTSP---QSFDDEHIEAD--------VSERLVNLLAQQQEELNVLRRKHKADIEVILKGVPEEHREETLTRC 608          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXX--------XXXXXXXXXXXXXXXNNFNHQSIG--ESAKENS-VETSW--------------------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPS 1218
            ++ E+DPTGRYGRY +VLGKGA K VYRAFDE +G+EVAWNQVK+ D +++  DL+RLY E+HLLKTLKH+NI+KFY SWVD    NINFITE+FTSGTLRQYR+KH  V++ A+K W RQIL GL YLHSH PP+IHRDLKCDN+FVNGNQGEVKIGDLGLAAIL+++ + H V GTPEFMAPE+YEEEYNELVDIY+FGMC+LE+VT EYPY EC +  QIYKKV SG KP +L KV DP V+ F+EKC++ AS RL A+ LL DPFLQ D             +    +    H+ +N +  S G  ES  E++  E  W                          + T++G++ +  +IFL+LRIAD+ GH+RNI+FPF+I ADT++SVA+EMV EL++TD +V+ IA+ ID E+   +P W P 
Sbjct:   16 EYAEVDPTGRYGRYNDVLGKGASKTVYRAFDEYQGMEVAWNQVKLHDFLQSPEDLERLYCEIHLLKTLKHRNIMKFYTSWVDVSRRNINFITEMFTSGTLRQYRQKHMRVNIWAVKHWCRQILSGLLYLHSHDPPIIHRDLKCDNIFVNGNQGEVKIGDLGLAAILRKSHAVHCV-GTPEFMAPEVYEEEYNELVDIYSFGMCVLEMVTFEYPYSECTHPVQIYKKVISGTKPEALYKVKDPMVRQFVEKCLATASRRLSARELLKDPFLQVDDLVFCPGDGDYSLMNYLRQPYLEHAYSNVSMMSNGLSESIDEDTPTEDRWDCEDDDIKADGIDLFNGHEDEPLGNVDITIKGRKSEDGSIFLRLRIADNDGHVRNIYFPFDIEADTALSVATEMVAELDITDHEVTRIAEMIDGEVSALVPDWRPG 443          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXX--------XXXXXXXXXXXXXXXNNFNHQSIG--ESAKENS-VETSW--------------------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPS 1218
            ++ E+DPTGRYGRY +VLGKGA K VYRAFDE +G+EVAWNQVK+ D +++  DL+RLY E+HLLKTLKH+NI+KFY SWVD    NINFITE+FTSGTLRQYR+KH  V++ A+K W RQIL GL YLHSH PP+IHRDLKCDN+FVNGNQGEVKIGDLGLAAIL+++ + H V GTPEFMAPE+YEEEYNELVDIY+FGMC+LE+VT EYPY EC +  QIYKKV SG KP +L KV DP V+ F+EKC++ AS RL A+ LL DPFLQ D             +    +    H+ +N +  S G  ES  E++  E  W                          + T++G++ +  +IFL+LRIAD+ GH+RNI+FPF+I ADT++SVA+EMV EL++TD +V+ IA+ ID E+   +P W P 
Sbjct:   16 EYAEVDPTGRYGRYNDVLGKGASKTVYRAFDEYQGMEVAWNQVKLHDFLQSPEDLERLYCEIHLLKTLKHRNIMKFYTSWVDVSRRNINFITEMFTSGTLRQYRQKHMRVNIWAVKHWCRQILSGLLYLHSHDPPIIHRDLKCDNIFVNGNQGEVKIGDLGLAAILRKSHAVHCV-GTPEFMAPEVYEEEYNELVDIYSFGMCVLEMVTFEYPYSECTHPVQIYKKVISGTKPEALYKVKDPMVRQFVEKCLATASRRLSARELLKDPFLQVDDLVFCPGDGDYSLMNYLRQPYLEHAYSNVSMMSNGLSESIDEDTPTEDRWDCEDDDIKADGIDLFNGHEDEPLGNVDITIKGRKSEDGSIFLRLRIADNDGHVRNIYFPFDIEADTALSVATEMVAELDITDHEVTRIAEMIDGEVSALVPDWRPG 443          

Query:   46 FVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNN--FNHQSIGESAKENSVETSW---------------EFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSW 1209
            FVEIDP+GRYGRY E+LGKGA K VYRAFDE EGIEVAWNQVK+ +  RN  +L++ + E+HLLKTL H+NI+KFY SWVD  N +INF+TE+FTSGTLRQYR +H+ V++RA+K+W +QIL+GL YLHS  PP+IHRDLKCDN+F+NGNQGEVKIGDLGLAAIL++ S A   +GTPEFMAPE+Y+EEYNELVD+YAFGMC+LE+VT +YPY EC + AQIYKKVTSG KP +   V DPEV+ F+EKC++  + RL A  LL DPFLQ D     V R       +        H  I +    +  E+S                + +++G+R   + IFL+LRI+D+ G IRNI+FPF    DT+ SVA EMV EL++T+QDV+ IA+ ID+EI   +P W
Sbjct:   14 FVEIDPSGRYGRYDEILGKGASKTVYRAFDEYEGIEVAWNQVKLRNFTRNPEELEKFFREIHLLKTLNHQNIMKFYTSWVDTNNLSINFVTELFTSGTLRQYRLRHRRVNIRAVKQWCKQILKGLLYLHSRSPPIIHRDLKCDNIFINGNQGEVKIGDLGLAAILRK-SHAVRCVGTPEFMAPEVYDEEYNELVDVYAFGMCVLEMVTFDYPYSECTHPAQIYKKVTSGKKPEAFYLVKDPEVREFVEKCLANVTCRLTALELLQDPFLQDDNMDGFVMRPIDYYNGYDETGVFLRHPLIDDPLYHDQFESSQICEIDLFANDDEDHVDISIKGKRNGDDGIFLRLRISDAEGRIRNIYFPFETAIDTAWSVAVEMVSELDITNQDVAKIAEMIDAEIAALVPDW 417          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWE---------------------------------FTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSW 1209
            + +EIDPT RY RY+EV+GKGA K V++ FDE++GIEVAWNQV++ DL+++   L+RLYSEV LLK+LKHKNII+FYNSW+D KN+ +N ITE+FTSG+LRQYRKKH+ V+++A+K W+RQIL GL YLHS  PP+IHRD+KCDN+F+NGN GEVKIGDLGLA +++QA +A SVIGTPEFMAPELY+E YNEL DIY+FGMC+LE+VT EYPY EC N+AQIYKKV+SGIKPASL+KV DPEV  FIEKC+  AS+RL A+ LL+D FL  +    +              +F  + +      N+   +                                   F ++G+  D N++ L LRI D +G +RNIHF F    DT+ +V+SEMVE+LELTD++V  IA+ ID  +   IP+W
Sbjct:   17 EVLEIDPTCRYIRYKEVIGKGASKTVFKGFDEVDGIEVAWNQVRIDDLLQSPDCLERLYSEVRLLKSLKHKNIIRFYNSWIDDKNKTVNIITELFTSGSLRQYRKKHRKVNMKAVKCWARQILTGLKYLHSQDPPIIHRDIKCDNIFINGNHGEVKIGDLGLATVMEQA-NAKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFEYPYCECRNSAQIYKKVSSGIKPASLSKVKDPEVMKFIEKCLLPASERLSAEELLLDSFLNVNGLVMNNPLPLPDIVMPKEGSFGERCLMSEGPPNARNRTMSMNLDEDNNLPIVISSNNSGTNCIEVRRAKRGNFFVLKGEENDENSVSLILRIVDENGRVRNIHFLFFQEGDTASNVSSEMVEQLELTDKNVKFIAELIDVLLVNLIPNW 437          

Query:   40 IDFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVET-SWEFTVEGQRR-DVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSET 1224
            I +VE DP+GRYGR+REVLGKGA K VY+AFD++ G+EVAWNQVK++++ R+   L RLYSEVHLLK L H++II++  SW+D      NFITE+FTSGTLR+YR+K++ VD+RA+K W+RQIL GL+YLH H PPVIHRDLKCDN+FVNG+ G+VKIGDLGLAAIL+ + +AHSVIGTPEFMAPELYEE+YNELVDIY+FGMC+LE++T EYPY EC N AQIYKKVTSG  P S   +   E + F+ KC+   S RLPAK LL DPFL +  + D              N   + ++ E     +  T + + ++ G+   + +TIFL+++I D  GH+RNI FPFNI +DT + VA EMV+ELE+TD D   IA  I++EI   +P+W  +++
Sbjct:   13 IAYVETDPSGRYGRFREVLGKGAMKTVYKAFDQVLGMEVAWNQVKLNEVFRSPEPLQRLYSEVHLLKNLNHESIIRYCTSWIDVNRRTFNFITELFTSGTLREYRRKYQKVDIRAIKSWARQILNGLAYLHGHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLAAILRGSQNAHSVIGTPEFMAPELYEEDYNELVDIYSFGMCVLEMLTGEYPYSECTNPAQIYKKVTSGKLPDSFHLIQHTEAQRFVGKCLETVSRRLPAKELLADPFLAATDERDLAPLFRLPQQLAIQNLAANGTVVEHLPSTTDPTRTTDMSITGKMNSEDHTIFLQVQILDGDGHMRNIQFPFNILSDTPLEVALEMVKELEITDWDPLEIAAMIENEISLLVPNWRANDS 409          

Query:   49 VEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXX------------------------XXXXXXXXXXXXNNFN--HQSIGESAKENSVETSWEFTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIP 1203
            VE+DPT RY RY EVLG+GA K VY+AFDE+EGIEVAW+QV++ +++++  +L+RLYSEVHLLK+LKH+N++KFYN WVD + + IN ITE+FTSG+LRQYR+KH  VDL+A+K W+RQ+L GL YLH+H+PP+IHRDLKCDN+FVNGN GEVKIGDLGLA ++     A SVIGTPEFMAPELY+E Y+ELVDIY+FGMC+LE+ T+EYPY EC NAAQI+KKV+ G+KPA+LAK+T+ + K FI+KC+  AS+RL AK LL DPFL SD     V                           S   +    N+    H+S+ E  + N    + E  + G++ D N++ L LRIAD  GH RNIHF F + +DT++SVA+EMVE+LEL D DV+ IA  ID  I   +P
Sbjct:   16 VEVDPTRRYIRYNEVLGRGAMKTVYKAFDEVEGIEVAWSQVEIDEVMQSPDNLERLYSEVHLLKSLKHENVMKFYNYWVDDQKKTINVITELFTSGSLRQYRQKHPRVDLKAIKNWARQVLRGLDYLHTHQPPIIHRDLKCDNIFVNGNHGEVKIGDLGLATVM-LTPRAKSVIGTPEFMAPELYDENYDELVDIYSFGMCMLEMFTLEYPYSECTNAAQIFKKVSKGVKPAALAKITNIQAKQFIDKCLVPASERLSAKELLQDPFLCSDNSSVLVGTKFPSSLPKSVDVSLEALHMDVDTNESMCTSTCKRNDLGGPHRSVLEFTRTNK---NTELKLTGEKLDDNSVSLVLRIADLCGHARNIHFLFYLDSDTAMSVAAEMVEQLELADCDVTFIADFIDLLIVNLVP 422          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRL-----------------------------PAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWE-----FTVEGQRRDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWNPSETPDN 1233
            + +E+DPT RY RY+EV+GKGAFK VY+AFDE++GIEVAWNQV++ D++++   L+RLYSEV LLK+LKH NII+FYNSW+D KN+ +N ITE+FTSG+LR YRKKH+ V+++A+K W+RQIL GL YLH  +PP+IHRDLKCDN+F+NGN GEVKIGDLGLA +++QA+ A SVIGTPEFMAPELY+E YNEL DIY+FGMC+LE+VT +YPY EC N+AQIYKKV+SGIKPASL++V DPEVK FIEKC+  AS+RL                             P +    D  L S+    +    + S      +N    +  +++    +E         F ++G+  D  ++ L LRI D +G +RNIHF F    DT+  V+SEMVE+LELTDQ+V+ IA+ ID  +   IP+W    T D+
Sbjct:   17 EVLEVDPTFRYIRYKEVIGKGAFKTVYKAFDEVDGIEVAWNQVRIDDVLQSPNCLERLYSEVRLLKSLKHNNIIRFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVNMKAVKNWARQILMGLRYLHGQEPPIIHRDLKCDNIFINGNHGEVKIGDLGLATVMEQAN-AKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFDYPYCECKNSAQIYKKVSSGIKPASLSRVKDPEVKQFIEKCLLPASERLSAKELLLDPFLQLNGLTMNNPLPLPDIVMPKEGAFGDRCLMSEGPPTTRPSKTLSIDLDEDSNLPIVTFSDNSGSRCIEVRRAKRGNFFVLKGEENDEQSVSLILRIVDENGRVRNIHFLFYQEGDTASKVSSEMVEQLELTDQNVTFIAELIDILLVNMIPTWKTDVTVDH 446          

Query:   43 DFVEIDPTGRYGRYREVLGKGAFKKVYRAFDELEGIEVAWNQVKVSDLVRNSVDLDRLYSEVHLLKTLKHKNIIKFYNSWVDAKNENINFITEIFTSGTLRQYRKKHKHVDLRALKKWSRQILEGLSYLHSHKPPVIHRDLKCDNLFVNGNQGEVKIGDLGLAAILQQASSAHSVIGTPEFMAPELYEEEYNELVDIYAFGMCLLELVTVEYPYIECANAAQIYKKVTSGIKPASLAKVTDPEVKAFIEKCISRASDRLPAKALLMDPFLQXXXXXXXXXXXXXXXXXXXXNNFNHQSIGESAKENSVETSWEFTVEGQR-RDVNTIFLKLRIADSSGHIRNIHFPFNIGADTSISVASEMVEELELTDQDVSTIAKTIDSEIQYHIPSWN---PSETPDNN 1236
            ++VE DPTGRYGR+ E+LG+GA K VY+A DE  GIEVAW+QVK+ +++R+SVDL RLYSEVHLL TL HK+II+FY SW+D  N  +NFITE+FTSGTLRQY+ K+  +D+RA+K W+RQILEGL YLH H PPVIHRDLKCDN+FVNG+ G+VKIGDLGLA +L+   SAHS+IGTPEFMAPELYEE YNEL+D+Y+FGMC LE++T E+PY EC + AQIYKKV  G  P +  +V D E + FI KC+  AS R+ AK LL DPFL              +    +   F +++  ++ K    E   E ++ G+   + N I L+++IA  +G   N+ FPF+I  DTSI VA EMV+ELE+ D +   IAK ID  I   +  W      ETP ++
Sbjct:    8 EYVETDPTGRYGRFAEILGRGAMKTVYKAIDEKLGIEVAWSQVKLKEVLRSSVDLQRLYSEVHLLSTLNHKSIIRFYTSWIDVHNHTLNFITELFTSGTLRQYKNKYLRIDIRAIKSWARQILEGLVYLHEHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLARMLRDCHSAHSIIGTPEFMAPELYEENYNELIDVYSFGMCFLEMITSEFPYSECNHPAQIYKKVVGGKLPGAFYRVGDIEAQRFIGKCLVSASKRVSAKELLQDPFL-----ASDESWMVYTSGAGNPKPFLNENEMDTLKLEDDELRTEMSIAGKLGAEDNKIDLEVQIAYDNGLANNVFFPFDIMNDTSIDVAKEMVKELEIIDWEPVEIAKMIDGAISSLVSDWKYEEDDETPHDH 404