Vfaba.Hedin2.R1.1g036600.1

Query:    1 MPKHRSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSDEDSSSLT------TLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGSVLSHS 582
            M K R+FFFFK  PP        SSP+N+TFSDAI+DENIETA  LITKWNSIST+SN+S   N+ +EAK YL AVK LQ AM YL+A+DSTS+KLI AQSLM+LAMK LETEF RIL QN +R+ S+S+SV S     R  S  DDEFSDEDSSSL+      T+ ++LKAIAECMIFTGYSKEC  +Y IVRKSI+DEAL+NLGVEKLSFSQ+QKMDWE LEWKIK W+NAVKV+VNTLF GER LC+YIF++PE+ I  SCFTEICK+GA+MLF FPENVAKCK TPEKMFR LDLYEAISDNWQ IE +F+S+S S I +QVI+S++RL E+VRTML+DFESAIQKE+SK+PVPGGGIHPLTRYVMNYI+LL+DY DA++DI  DWPQ+PLPESYYK PSHDE NPPSEI+KRLSWLIL +LCKLDGK+ELYKD+ALSYLFLANNMQYVVVKVR SNLGFILGEDWL+KHEMKVKEYV+KYERMAWSKVLSSIPENPTA+N S IFQNFN+AFEEA RTQ LWVVPDP MR+EI   L++ VV KYREFY+KYRVGL+SV+ YSPEDL +YLSEILCGSV SHS
Sbjct:    1 MSKPRNFFFFKQSPPPPQLPP--SSPRNKTFSDAIIDENIETAHCLITKWNSISTTSNHSYLFNNTEEAKHYLKAVKSLQSAMQYLVAQDSTSKKLIAAQSLMQLAMKNLETEFCRILGQNRDRFNSESVSVRSRTSSDRRSSFSDDEFSDEDSSSLSAESVSMTVIADLKAIAECMIFTGYSKECAKLYVIVRKSIVDEALYNLGVEKLSFSQIQKMDWEVLEWKIKTWLNAVKVAVNTLFHGERTLCDYIFESPEKKITDSCFTEICKDGAMMLFSFPENVAKCKKTPEKMFRTLDLYEAISDNWQQIELIFSSESNSTIRSQVISSQVRLGETVRTMLTDFESAIQKESSKVPVPGGGIHPLTRYVMNYIALLSDYGDAIADIVFDWPQSPLPESYYKNPSHDENNPPSEIAKRLSWLILVVLCKLDGKAELYKDVALSYLFLANNMQYVVVKVRKSNLGFILGEDWLMKHEMKVKEYVTKYERMAWSKVLSSIPENPTADNVSGIFQNFNVAFEEAFRTQYLWVVPDPKMREEIGAWLDVNVVYKYREFYVKYRVGLNSVIRYSPEDLRNYLSEILCGSVSSHS 586          

Query:   27 QNQTFSDAIVDENIETAQSLITKWNSISTSSNYS--LFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSD-----EDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERN-IAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCG 576
            QN+TFSDAIVDENIETA++LITKWN++STSSN+S  LFTN+ QEAK+YL AVK LQ AMMYL+ARDSTS+KL+ AQSLM+LA+KKLE EFY ILSQN +R+ S+S+S  S+ D R S S+ +    D      DS S++ + ++LKAIAECMIFTGYSKECVN+Y IVRKSIMDEAL+NLGVE LSFSQ+QKMDWE LE+K+KCW+NAVKV+VNTLF GER+LCNYIFD+PE+N I  SCF +IC+E A+MLF FPENVAKCK TPEKMFR LDLYEAIS+NW  IES+F+S+S SPI +QV+AS++RL E+VRTML+DFESAIQKE+SKIPVPGGGIHPLTRYVMNYI+LL DYS+A+ DI SDWPQTP+PESYYK P HDE NPPSEI+KRLSWLIL +LCKLDGK+E YKD+ALSYLFLANNMQYVVVKVR SNL FILGEDWL+KHEMKVKEYV+KYERMAWSKVLSSIPENPT E AS+ FQ FN+ F+EA R Q LWVVPD  +R+EIKESL  K+V KYREFY+K+RVGLDSV+ YSPEDL +YLSEIL G
Sbjct:   25 QNKTFSDAIVDENIETARTLITKWNTVSTSSNHSNSLFTNTRQEAKRYLKAVKSLQSAMMYLVARDSTSKKLVEAQSLMQLAIKKLENEFYGILSQNRDRFDSESISFRSSTDRRSSSSDEEFSDDDGSSLAADSVSMSAV-ADLKAIAECMIFTGYSKECVNIYLIVRKSIMDEALYNLGVENLSFSQIQKMDWEMLEYKMKCWLNAVKVAVNTLFHGERILCNYIFDSPEKNNIGESCFADICRESALMLFAFPENVAKCKKTPEKMFRTLDLYEAISENWNQIESIFSSESNSPIRSQVVASQVRLGETVRTMLTDFESAIQKESSKIPVPGGGIHPLTRYVMNYIALLADYSEAIGDIVSDWPQTPVPESYYKSPIHDEDNPPSEIAKRLSWLILVVLCKLDGKAEFYKDVALSYLFLANNMQYVVVKVRKSNLRFILGEDWLLKHEMKVKEYVTKYERMAWSKVLSSIPENPTVEKASENFQGFNVEFDEAFRMQYLWVVPDLELRNEIKESLVSKIVFKYREFYVKFRVGLDSVIRYSPEDLKEYLSEILRG 581          

Query:    1 MPKH--RSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYS----LFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLS-----VESTVDHRRSISEIDDEFSDEDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGSVLSHSTTDHF----KRFK 591
            MPK   ++FFFFK  P        P+S    TFSD++++ENIETA+++I+KW+ IS+S        LF+N+ QEAKQYL+AV  LQ  M +L+ARDS+S+ LI AQSLM+LAMK+L+TEFYRIL+QN +    +S++       S  D     SE +  F+ +  S++    ++LKAIAECM+  GYSKECV +Y ++RKSI+DE L++LGVEKLSFSQVQKMDWE LE KIKCW+NAVKV+V TLF GER LC+Y+F +PER IA SCF  IC+EGA  LFGFPENVAKCK TPEKMFR LDLYEAISDNWQ I S+F+ +STS + +Q  AS +RL E+VRTML+DFESAIQKE+SKIPVPGGGIHPLTRYVMNYI+ L DY DAL+DI +DWPQ PLPESYY+  +H+  N  SE+++R++WLIL +LCKLDGK+ELYKD+ALSYLFLANNMQYVVVKVR SNLGFILGEDWL KHE KVKEYVSKYER+ W+KV   + ENPTAE    IF++F +AF +ACR Q  W+VPD  +RDEIK S    +  K  EF+ K R+G D+ + +SP DL +YLS+ILCG   S S + H     +RFK
Sbjct:    1 MPKMGLKNFFFFKTSPSPPSSHPTPTSTSIITFSDSLMEENIETARTIISKWDPISSSDQSHCPSPLFSNTRQEAKQYLDAVMRLQSTMQHLVARDSSSESLIQAQSLMQLAMKRLQTEFYRILAQNRDNLDPESVTSTDRRSSSVSDDDDDFSEDEFRFAGDSVSTVAM--ADLKAIAECMVSAGYSKECVKIYILMRKSIVDETLYHLGVEKLSFSQVQKMDWEVLESKIKCWLNAVKVAVGTLFHGERTLCDYVFGSPERKIAESCFAAICREGAASLFGFPENVAKCKKTPEKMFRTLDLYEAISDNWQQIASIFSPESTSSVRSQATASLVRLGEAVRTMLTDFESAIQKESSKIPVPGGGIHPLTRYVMNYIAFLADYGDALADIVADWPQNPLPESYYRSSNHEGKNRSSEVAERIAWLILVLLCKLDGKAELYKDVALSYLFLANNMQYVVVKVRKSNLGFILGEDWLTKHESKVKEYVSKYERVGWTKVFPLLQENPTAEERRAIFESFGVAFHDACRAQSSWIVPDQKLRDEIKVS----IASKLAEFFEKLRIGSDTEIGFSPYDLGNYLSDILCGRGQSGSVSLHTPSPPRRFK 600          

Query:    5 RSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLS---VESTVDHRRSISEIDDEFSDEDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGSVLSHSTT 584
            R+ FF K  P      LPP S   +TFSD+++DENIETA+SLI+KW+  + S++  LF N+ QEAKQYL+AV  LQ  M YL+ARDS+S  LI AQSLM+LAM +L+ EFYRIL+QN +    +S++     S+          +D+F     S  T   ++LKAIAECM+  GY KECV VY ++RKS++DEAL++LGVE+LSFSQVQKMDWE L  KIKCW+NAVK++V TLF  E+ LC+Y+F +PER IA SCF  +C+EGA  LFGFPENVA+CK TPEKMFR LD+YEA+S+NW  I S+F+S+ TS + +Q  AS ++L E+VRTML+DFESAIQKE+S+IPVPGGGIHPLTRYVMNYI+ L DY DAL+DI + WPQ PLPESYY+ P  +E N  SEI++R++WLIL +LCKLDGK+ELYKD+ALSYLFLANNMQYVVVKVR SNLGFILGE+WL KHE KVKEYVSKYER+ WSK    +PENPT E A  IF++FN AF EACR Q  WVVPDP +R+EIK S+ LK+V +Y+E   KYRVG ++V  +  ED+  YL EILCGS  S S +
Sbjct:    4 RNIFFSKTTP------LPPPS---RTFSDSLMDENIETARSLISKWDP-NNSASAPLFRNTRQEAKQYLDAVVSLQTTMQYLVARDSSSLSLIQAQSLMQLAMNRLQMEFYRILTQNRDNLDPESVASTDRRSSSVSDDDDDFSEDDFRFAGDSVSTVAMADLKAIAECMVSAGYRKECVKVYILMRKSVVDEALYHLGVERLSFSQVQKMDWETLHSKIKCWLNAVKIAVRTLFHAEKTLCDYVFGSPERMIAESCFAAVCREGAASLFGFPENVARCKKTPEKMFRTLDMYEAMSENWNQIASIFSSEPTSSVRSQATASLVKLGEAVRTMLTDFESAIQKESSRIPVPGGGIHPLTRYVMNYIAFLADYRDALADIVAGWPQNPLPESYYRSPDREEKNRSSEIAERIAWLILVVLCKLDGKAELYKDVALSYLFLANNMQYVVVKVRKSNLGFILGEEWLTKHEAKVKEYVSKYERVGWSKAFPLLPENPTPEEARGIFESFNAAFHEACRVQSTWVVPDPNLREEIKASIGLKLVARYKEMCGKYRVGSETVSGFWSEDMEHYLGEILCGSGESRSVS 576          

Query:    1 MPKH--RSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYS-LFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRS-ISEIDDEFSDED----SSSLTTLE-SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGSVLSHSTTDHFKRFK 591
            MPK   ++ FFFK  P         SS   +TFSD+++D+NIETA+++I+KW  IS S   + LF+N+ QEAKQYLNAV  LQ  M +L+A DS+S  LI A  LM+LAMK+L+TEFYRIL+QN +    +S++   + DHR S +S+   +FSD++      S++T+  ++LKAIAECM+  GYSKECV +Y ++RKS++DEAL++ GVE+L+FSQ+QKMDWE LE KIK W+NAV+ +V TLF GE+ LC+Y+F +PER IA SCF  +C+EGA  LF FPE VAKCK TPEKMFR LDLYEAISDN Q IES+F+S+STS I +QV  S+ RL E+ RTML +FESAIQKE+SKIP+PGGGIHP+TRYVMNYI+ L DY DAL++I +DWPQ  LPESYY+ P  +  N  SEI++R++WLIL +LCKLDGK+ELYK++ALSYLFLANNMQYVVVKVRNSNLGFILGEDWL KHE+KVKEYVSKYE + W+KV  S+PE PTAE A  I + F++AF +AC+ Q  WVVPDP +R+EIK S+  K V  +RE + KY+VG ++V   +P+DL   LS+IL GSV S  +     RFK
Sbjct:    1 MPKMGLKNLFFFKTSPSPP------SSSPTRTFSDSLMDQNIETARAIISKWELISPSDQAAPLFSNTRQEAKQYLNAVMSLQSTMQHLVALDSSSDTLIQAHFLMQLAMKRLQTEFYRILTQNRDNLDPESVA---STDHRSSSVSDDGTDFSDDEFRFAGDSVSTVAMADLKAIAECMVSAGYSKECVKIYILMRKSMVDEALYHFGVERLTFSQIQKMDWEVLESKIKSWLNAVRFAVRTLFHGEKTLCDYVFGSPERKIAESCFAAVCREGAESLFAFPEKVAKCKKTPEKMFRTLDLYEAISDNRQQIESIFSSESTSCIRSQVTVSQARLGEAARTMLINFESAIQKESSKIPLPGGGIHPVTRYVMNYIAFLADYGDALAEIVADWPQNSLPESYYRSPDREGKNRSSEIAERMAWLILVLLCKLDGKAELYKEVALSYLFLANNMQYVVVKVRNSNLGFILGEDWLTKHELKVKEYVSKYEHVGWNKVFLSLPETPTAEQARAILECFDVAFHDACKAQFSWVVPDPKLREEIKASIASKFVPSHRELFEKYQVGSETVFGLTPDDLEHSLSDILSGSVSSSHSPSPPHRFK 591          

Query:    1 MPKH--RSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYS-LFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRS-ISEIDDEFSDED----SSSLTTLE-SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGSVLSHSTTDHFKRFK 591
            MPK   ++ FFFK  P         SS   +TFSD+++D+NIETA+++I+KW  IS S   + LF+N+ QEAKQYLNAV  LQ  M +L+A DS+S  LI A  LM+LAMK+L+TEFYRIL+QN +    +S++   + DHR S +S+   +FSD++      S++T+  ++LKAIAECM+  GYSKECV +Y ++RKS++DEAL++ GVE+L+FSQ+QKMDWE LE KIK W+NAV+  V TLF GE+ LC+Y+F +PER IA SCF  +C+EGA  LF FPE VAKCK TPEKMFR LDLYEAISDN Q IES+F+S+STS I +QV  S+ RL E+ RTML +FESAIQKE+SKIP+PGGGIHPLTRYVMNYI+ L DY DAL++I +DWPQ  LPESYY+ P  +  N  SEI++R++WLIL +LCKLDGK+ELYK++ALSYLFLANNMQYVVVKVRNSNLGFILGEDWL KHE+KVKEYVSKYE + W+KV  S+PE PTAE A  I + F++AF +AC+ Q  WVVPDP +R+EIK S+  K V  +RE + KY+VG ++V   +P+DL   LS+IL GSV S  +     RFK
Sbjct:    1 MPKMGLKNLFFFKTSPSPP------SSSPTRTFSDSLMDQNIETARAIISKWELISPSDQAAPLFSNTRQEAKQYLNAVMSLQSTMQHLVALDSSSDTLIQAHFLMQLAMKRLQTEFYRILTQNRDNLDPESVA---STDHRSSSVSDDGTDFSDDEFRFAGDSVSTVAMADLKAIAECMVSAGYSKECVKIYILMRKSMVDEALYHFGVERLTFSQIQKMDWEVLESKIKSWLNAVRFVVRTLFHGEKTLCDYVFGSPERKIAESCFAAVCREGAESLFAFPEKVAKCKKTPEKMFRTLDLYEAISDNRQQIESIFSSESTSCIRSQVTVSQARLGEAARTMLINFESAIQKESSKIPLPGGGIHPLTRYVMNYIAFLADYGDALAEIVADWPQNSLPESYYRSPDREGKNRSSEIAERMAWLILVLLCKLDGKAELYKEVALSYLFLANNMQYVVVKVRNSNLGFILGEDWLTKHELKVKEYVSKYEHVGWNKVFLSLPETPTAEQARAILECFDVAFHDACKAQFSWVVPDPKLREEIKASIASKFVPSHRELFEKYQVGSETVFGLTPDDLEHSLSDILSGSVSSSHSPSPPHRFK 591          

Query:    1 MPKH--RSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFS-DEDSSSLTTLE-------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIF--DTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENP----TAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILC 575
            MP+   RS FF   P       LPP S Q +TFSD+++DENIETA+ LITKW+    ++   LF+ + QEAKQYLNAVK LQ AM YL+A+DSTS  L+ AQ LM+LAMK L+ EFY+ILS N      +++S  S+VDHR S+S+ DDE S  ED   ++  E        +LKAIAECMI +GY KECV VY ++RKSI+DEAL++LGVEKL+ SQVQK+DWE LE KIK W+ AVKV+V TLF GER+LC+++F  D+ +R IA SCF EI K+GA+ L GFPE VAKCK +PEKMFR+LDLYEAISD W  IE +F+ +ST  I  Q + S ++L ++VRTML+DFE+AIQKE+SK PVPGGG+HPLTRYVMNY++ L DYS  L DI +D PQ+PLPESYY+ P  +E  P SE+S+R++W+IL +LCKLDGK+ELYKD+A SYLFLANNMQYVVVKVR SNLGF+LGE+WL KHE+KV+EY SKYE + WS V SS+PENP    TAE A   F  F+ AF EAC+ Q  WVV DP  RDEIK+S+  K++ KY  F+ K RVG  SV  + P+D+  YLS ILC
Sbjct:    1 MPRKGMRSIFFTSTPTA----SLPPPSRQ-RTFSDSLMDENIETAEKLITKWDDSKVTTTTQLFSGTRQEAKQYLNAVKGLQSAMQYLVAQDSTSSTLVRAQFLMQLAMKTLQKEFYQILSSNREHLDPETVSTRSSVDHRSSVSDYDDEISITEDEFRVSETERVSMLAMEDLKAIAECMISSGYGKECVKVYIVMRKSIVDEALYHLGVEKLNLSQVQKLDWEVLELKIKSWLKAVKVAVGTLFNGERILCDHVFAADSGKR-IAESCFAEITKDGAVSLLGFPEMVAKCKKSPEKMFRILDLYEAISDYWPQIEFIFSFESTVNIRTQTVTSMVKLGDAVRTMLTDFETAIQKESSKKPVPGGGVHPLTRYVMNYLTFLADYSGVLVDIIADLPQSPLPESYYRSPMREENPPASELSERIAWIILVVLCKLDGKAELYKDVAHSYLFLANNMQYVVVKVRKSNLGFLLGEEWLAKHELKVREYTSKYESVGWSAVFSSLPENPAAELTAEQARACFVRFDAAFHEACKKQASWVVSDPKFRDEIKDSIASKLMQKYSVFFEKNRVGSKSVRDFLPDDIGKYLSNILC 585          

Query:    1 MPKH--RSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFS-DEDSSSLTTLE-------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIF--DTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENP----TAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILC 575
            MP+   RS FF   P       LPP S Q +TFSD+++DENIETA+ LITKW+    ++   LF+ + QEAKQYLNAVK LQ AM YL+A+DSTS  L+ AQ LM+LAMK L+ EFY+ILS N      +++S  S+VDHR S+S+ DDE S  ED   ++  E        +LKAIAECMI +GY KECV VY ++RKSI+DEAL++LGVEKL+ SQVQK+DWE LE KIK W+ AVKV+V TLF GER+LC+++F  D+ +R IA SCF EI K+GA+ L GFPE VAKCK +PEKMFR+LDLYEAISD W  IE +F+ +ST  I  Q + S ++L ++VRTML+DFE+AIQKE+SK PVPGGG+HPLTRYVMNY++ L DYS  L DI +D PQ+PLPESYY+ P  +E  P SE+S+R++W+IL +LCKLDGK+ELYKD+A SYLFLANNMQYVVVKVR SNLGF+LGE+WL KHE+KV+EY SKYE + WS V SS+PENP    TAE A   F  F+ AF EAC+ Q  WVV DP  RDEIK+S+  K++ KY  F+ K RVG  SV  + P+D+  YLS ILC
Sbjct:    1 MPRKGMRSIFFTSTPTA----SLPPPSRQ-RTFSDSLMDENIETAEKLITKWDDSKVTTTTQLFSGTRQEAKQYLNAVKGLQSAMQYLVAQDSTSSTLVRAQFLMQLAMKTLQKEFYQILSSNREHLDPETVSTRSSVDHRSSVSDYDDEISITEDEFRVSETERVSMLAMEDLKAIAECMISSGYGKECVKVYIVMRKSIVDEALYHLGVEKLNLSQVQKLDWEVLELKIKSWLKAVKVAVGTLFNGERILCDHVFAADSGKR-IAESCFAEITKDGAVSLLGFPEMVAKCKKSPEKMFRILDLYEAISDYWPQIEFIFSFESTVNIRTQTVTSMVKLGDAVRTMLTDFETAIQKESSKKPVPGGGVHPLTRYVMNYLTFLADYSGVLVDIIADLPQSPLPESYYRSPMREENPPASELSERIAWIILVVLCKLDGKAELYKDVAHSYLFLANNMQYVVVKVRKSNLGFLLGEEWLAKHELKVREYTSKYESVGWSAVFSSLPENPAAELTAEQARACFVRFDAAFHEACKKQASWVVSDPKFRDEIKDSIASKLMQKYSVFFEKNRVGSKSVRDFLPDDIGKYLSNILC 585          

Query:    3 KHRSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNSISTSSNYS-LFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSDEDSSSLT---TLESN---------LKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTP-ERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASD----IFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGS 577
            + RS FF     P  P    PSSP  +TFSD++++EN E A+SLITKWNS++  S+ + LF  +  EAKQYLN VK LQ  M YL+A+D  S+ L+ +Q LM+LAMK LE EFYRILS N     S+++S   + D R S S+ DDE +++D   +T   T E++         LKAIA+CMI +GY +ECV +Y I+RKSI+DEAL++LGVE+LSFSQVQKM+WE +E KIK W+NAVK +V T+F GER+LC++IF T  E+  A SCF EI +EGA++LFGFPE VAKCK TPEK+F+ LDLYEAISDNW  +ES+F+ +STS +    + S L+L+++VR MLS+FESAIQK++SK+PVP GG+HPLTRYVMNYI+ L+DYS  L DI +D PQ+PLPE+YY+ P  DE    S+IS+R++WLIL +LCKLD K+ELY D+ALSY+FLANNMQYVVVKVR SNLGF+LG+DWL KHE KVKEY+SKYER+ W  VLSS+PENPTAE  ++     F +FN AF+EACR Q  W+V D  +RDEIK S+  KV  KY+EFY K+  G D V    PEDL +YLS IL G+
Sbjct:    5 RMRSIFFKSSTLPILP--FSPSSPY-RTFSDSLMEENFENAESLITKWNSVTDKSSLTPLFNGTRLEAKQYLNVVKGLQSTMKYLVAQDPNSKTLVRSQFLMQLAMKTLEKEFYRILSSNREYLDSETVSNRFSTDRRISFSDYDDEITEDDQFGVTGNSTSETDRMSMIAMADLKAIADCMISSGYGRECVKIYIIMRKSIVDEALYHLGVERLSFSQVQKMEWEVVELKIKTWLNAVKAAVGTVFYGERMLCDHIFSTATEKKFAESCFAEITREGALLLFGFPEMVAKCKKTPEKLFKTLDLYEAISDNWPQVESIFSFESTSGVRTAAVTSLLKLSDAVRAMLSEFESAIQKDSSKVPVPAGGVHPLTRYVMNYITFLSDYSSVLGDIIADCPQSPLPETYYRSPMRDENPLISDISERIAWLILLVLCKLDAKAELYNDVALSYMFLANNMQYVVVKVRRSNLGFLLGQDWLAKHETKVKEYLSKYERVGWGNVLSSLPENPTAEMTAEQIRAAFMSFNAAFQEACRKQSTWIVLDAKLRDEIKISIASKVEDKYKEFYEKHWSGSDPVNGLLPEDLRNYLSHILHGN 594          

Query:   28 NQTFSDAIVDENIETAQSLITKWNSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRS---ISEIDDEFS-DEDSSSLTTLE-------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIF--DTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENP----TAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGS 577
             +TFSD+++DENIETA+ LITKW+     +  +LF+ + QEAKQYLNAVK LQ AM YL+A+DSTS  L+ AQ LM+LAMK L+ EFY+ILS N      ++++  S+VD R     +S+ DDE S  ED   ++  E        +LKAIAE MI +GY KECV VY I+RKSI+DEAL++LGVEKLS SQVQK+DWE LE KIK W+  VKV+V TLF GER+LC+++F  D+ +R IA SCF EI K+GA+ LFGFPE VAKCK TPEKMFR+LDLYEAISD    IES+F+ +STS I +Q + S ++L ++VRTML+D E+AIQKE+SK PVPGGG+HPLTRYVMNY++ L DYS  L DI +D PQ+PLPESYY+ P  +E  P SE+S+R++W+IL +LCKLDGK+ELYKD+A SYLFLANNMQYVVVKVR SNLGF+LGE+WL KH++KV+EY SKYER+ WS V S++PENP    TAE A   F  F+ AF EACR Q  W V DP  RDEIK S+  K+V KY EFY K RVG +SV  + P+D+  YLS ILC  
Sbjct:   27 QRTFSDSLMDENIETAEKLITKWDDSKVPTTTALFSGTRQEAKQYLNAVKGLQSAMQYLVAQDSTSSTLVRAQLLMQLAMKTLQKEFYQILSSNREHLDPETVTTRSSVDLRSVSDYVSDYDDEISITEDEFRVSETERVSMLAMEDLKAIAESMISSGYGKECVKVYIIMRKSIVDEALYHLGVEKLSLSQVQKLDWEVLELKIKSWLQVVKVAVGTLFHGERILCDHVFASDSGKR-IAESCFAEITKDGAVSLFGFPEMVAKCKKTPEKMFRILDLYEAISDYLPQIESIFSFESTSNIRSQAVTSMVKLGDAVRTMLTDLETAIQKESSKKPVPGGGVHPLTRYVMNYLTFLADYSGVLVDIIADLPQSPLPESYYRSPMREENPPASELSERIAWIILVVLCKLDGKAELYKDVAHSYLFLANNMQYVVVKVRKSNLGFLLGEEWLDKHKLKVREYASKYERVGWSAVFSALPENPAAELTAEQARACFVRFDAAFHEACRKQASWFVSDPKFRDEIKGSIASKLVQKYSEFYEKNRVGSESVRGFLPDDIGKYLSNILCNG 592          

Query:   24 SSPQNQTFSDAIVDENIETAQSLITKW--NSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSD--------EDSSSLTTLE-------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWP---QTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPT---AENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKY------RVGLDSVVSYSPEDLTDYLSEILCGS 577
            +SP NQ F+ A+++E +ETA S+I KW  N+ S +   SLF +S +EAK+++  V+ L+ AM +L+++DS S KL  AQ+LM++AM +LE EF++ILS N ++   +S+S +S++       ++     D        +   S+T +E       S+LKAIAE MI  GY KECV +Y  VRKSI+DE L  LG+E    S+  + DW  LE  IK WI A K+ + TLF GE++LC+++F +   +   SCF EI  E A  LF FPE VAK K + E++F ++DL  AISD WQ IE +F  D+ + + +Q + S  +L  S+ + L+DFES IQK+ +K   PGGGIH LTR  MN+IS L+ YS  LS+I +D P    T L ESY + P  ++      +S   +WLIL +LCKLD K+E YKD++LSYLFLANN+Q ++  V ++ L  +LG+DWL KHE K+  Y   YE  AWS V  S+PE PT    E A   F+ F+ AFEEA   Q   VVP+  +RDE+K S+  K+V +YREFY KY         ++ +V + P++L +Y+S++  G+
Sbjct:   30 ASPLNQNFTQAMMEETVETADSVIRKWDPNTPSFTKIVSLFNHSRKEAKEFIRCVRDLRRAMHFLVSQDSQSPKLALAQTLMQIAMARLEKEFFQILSSNRDKLDPESVSGQSSISSNSEFEDVMGSDDDDESDNEMRKAGESITQVEKASAMVMSDLKAIAESMISCGYGKECVKIYKRVRKSIVDEGLSLLGIEIYKGSRFHRTDWVTLEHMIKNWIKAAKIGIATLFRGEKLLCDHVF-SASNSTRESCFYEIANEAATNLFKFPEFVAKEKKSHERIFPLMDLQAAISDLWQDIEMIFHFDAVAGVKSQALTSLQKLKVSIHSALTDFESIIQKDTTKALTPGGGIHKLTRSTMNFISSLSKYSGVLSEILADHPLPRNTRLLESYVRAPISEDEQHNHALSVHFAWLILVLLCKLDTKAEHYKDVSLSYLFLANNLQIIIETVGSTPLRNLLGDDWLNKHEDKLCAYAGNYEIAAWSNVFMSLPEEPTDLSPEEAKIYFRRFHTAFEEAYMKQSSRVVPNAKLRDELKVSIAKKLVPEYREFYRKYLPMLGQERNIEILVRFKPDNLENYISDLFHGT 611          

Query:   36 VDENIETAQSLITKWNSISTSSNYSLFTNSPQE-AKQYLNAVKMLQYAMMYLIARDS---TSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSL------SVESTVDHRRSISEIDDEFSDEDSSSLTTLE--------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVL-SSIPENPTAENA----------------SDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDS------VVSYSPEDLTDYLSEILCG 576
            +D  ++ A+ ++++++ +  +    L    P E  + YL+A+  L+  + Y ++  S   +   L  A SL+  A  KLE EF ++L+  +       L      S+  + D            +D+  ++  TL           L  +A+ M+  G+ ++ + +Y   R  +++E+L  LGVEKLS   VQ+M WE LE KI  WI+ ++++V  LF GER +C+ IF   + +++  CF E+      ML  F + +A+ K +PEK+F +LD+YE + +    IE++F   +   I         RLA++ +    DFE A++K+ +K  V  G +HPLT YV+NY+  L DY            QT L + + +  + D++N  S+++     ++  +   LDGKS+ YKD AL++LFL NN+ Y+V  VR S    +LG+DW+ +H   V+++ ++Y+R+AW+K+L SS  +  T+                    + F+ FN+ F+E  + Q  W VPD  +R+ ++ ++   ++  YR F  ++   ++S       + Y+ EDL   L E+  G
Sbjct:   66 IDRTLKAAEVILSQFDLLRQAETKVL--KGPHEDLESYLDAIAQLRKIIRYFMSNKSFKSSDGVLNHANSLLAKAQSKLEEEFKQLLASYSKAVEPDRLFDGLPNSLRPSSDGDGGGKPHGGHHNDDAETAAYTLPILIPSRVLPLLHDLAQQMVQAGHQQQLLQIYRDTRSFVLEESLKKLGVEKLSKEDVQRMQWEVLEAKIGNWIHFMRIAVKLLFAGERQVCDQIFRGFD-SLSDQCFAEVTVSSVSMLLSFGDAIARSKRSPEKLFVLLDMYEIMRELHTEIETIFKGKACLEIRDSATGLTKRLAQTAQETFGDFEEAVEKDATKTAVLDGTVHPLTSYVINYVKFLFDY------------QTTLKQLFLEFGNGDDSN--SQLASVTMRIMQALQNNLDGKSKQYKDPALTHLFLMNNIHYMVRSVRRSEAKDLLGDDWVQRHRRIVQQHANQYKRVAWTKILQSSSAQGLTSSGGGSLEGGNSSGVSRGLLKERFKMFNMQFDELHQRQSQWTVPDTELRESLRLAVAEVLLPAYRSFLKRFGPLVESGKNPQKYIKYTAEDLERLLGELFEG 630          

Query:   96 LITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHR---RSISEIDDEFSDEDSSSLTTLE-----------------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSC-----FTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDI-------FQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYR----VG--LDSVVSYSPEDLTDYLSEILCGS 577
            L  A  +M+ AM ++E EF  ++ +    +G         ++HR       + D +F++ D   +   +                 ++L  +A+ M+  G+ K C +VYS  R+  ++E++  LG++KLS  +V KM W+ LE +I  WI A  V++  LFP ER LC+ +F        FS      F E+C+   I L  F + +A    +PE++F+VLD++E + D     ES+F+    S +  + +    RL E++R +  + E+ I+++ +K  VPGGG+HP+TRYVMNY+         L  +F         E    +PS D     + ++ ++SW++  +   L+ KS++YKD AL Y+FL NN +Y+V KV++ +LG +LG+DW+ KH +KVK+Y   Y+R +W+K+L  +  + TA   + +        + FN+ F+E C+    WVV D  +++E+K SL   +V  Y  F  +++    +G   D  + Y  ED+   ++E+  G+
Sbjct:  119 LTRADDMMQQAMFRIEEEFRSLMERGAESFGLNPQGDAGAMNHRFDSEEEEDDDRDFNNGDDIQIPVAQPLTDYDLIIDALPSATINDLHEMAKRMLGAGFGKACSHVYSSCRREFLEESMSRLGLQKLSIEEVHKMPWQELEDEIDRWIKAANVALRILFPSERRLCDRVF------FGFSSAADLSFMEVCRGSTIQLLNFADAIAIGSRSPERLFKVLDVFETMRDLMPEFESVFSDQFCSVLRNEAVTIWKRLGEAIRGIFMELENLIRRDPAKAAVPGGGLHPITRYVMNYLRAACRSRQTLEQVF---------EESNGVPSKD----STLLTVQMSWIMELLESNLEVKSKVYKDPALCYVFLMNNGRYIVQKVKDGDLGLLLGDDWIRKHNVKVKQYHMNYQRSSWNKMLGLLKVDNTAAGMNGLGKTMKEKLKQFNIQFDEICKVHSTWVVFDEQLKEELKISLARLLVPAYGSFIGRFQNLGDIGKNADKYIKYGVEDIEARINELFKGT 619          

Query:  162 SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIF-DTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYR 552
             +L AIA  M+  G++KEC  VYS  R+  ++E+L  L +  LS  +VQ+  W+ LE +I  WI AV +  +  FP ER+LC+ +F D P  ++    F E+C+     L  F + +A     PE++F+V+DLYEA+ D    +E+LF+    SP+  + +A   RL E++R +  + E+ I+++  K   PGGGIHP+TRYVMNY+        +L  I     QT           ++  +    +S ++ W++  +   L+GK   Y+D +L +LF+ NN +Y++ K +++ LG +LGEDW++KH  K+++Y S Y R +W++V+  +  +       +  + F   F+E C+ Q  WVV D  +R+E++ S+   V   Y  F  + +
Sbjct:  187 GDLNAIAVRMVAGGFAKECSRVYSSRRREFLEESLSRLHLRGLSMEEVQESPWQDLEDEIDRWIKAVTLIFHVFFPSERLLCDRVFSDLPVSSVTDLSFMEVCRGTTTQLLNFADAIALGSRLPERLFKVVDLYEAMQDLIPKMETLFSDRYCSPLRHEALAIHKRLGEAIRGIFMELENLIRRDPPKTAFPGGGIHPITRYVMNYLRAACKSRQSLEQILD---QT----------GNETGSDTRPLSVQIIWVLELLESNLEGKKRTYRDPSLCFLFMMNNDKYILDKAKDNELGLVLGEDWIVKHAAKLRQYHSNYRRSSWNQVVGLLRTDGPYPKLVENLRLFKSQFDEVCKVQSQWVVSDGQLREELRSSVAGIVSPAYSNFIRRLK 565          

Query:   60 SLFTNSPQEAKQYLNAVKMLQYAMMYLIA---RDSTSQKLITAQSLMKL--AMKKLETEFYRILSQNTNRYGSKSLSVEST---VDHRRSISEIDDEF-----SDEDSSSLTTLES----------NLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSD-WPQTPLPESYYK--IPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPE-NPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMK--YRVGLDSVVSYSPEDLTDYLSEIL 574
            ++F     EA Q+  A+  +Q  ++   A   + +  +K +  Q+ + L  AM +LE E   +L Q+        L+V S    + +  S   +DDE      S ED   ++   +          ++KAIA  M    Y +     +  V++  ++E +  L +E+ S   V +MDWE L   ++ W   VK+        E+ LC+ I    E +I+ +CF EI K+  + L  F E V      PE + R L +YE  ++    +++LF  ++ S +         +LA+   T    F+ AI  + S  P  GGGIH LTRYVMNY+ LL +Y+D+L+ +  +      +PE   +  +PS       S +++ L  ++ T+   L+ K++LY D AL  +FL NN +Y+V KV+ S L  + G++W+ KH    +  V+ YER  WS +L+ + + N +     +  + F+LAF++  + Q  W VPD  +RD++  S  +KVV  YR F  +   R+G +  + Y+ ED+ + L ++ 
Sbjct:   88 TMFEAGLSEADQFFQALYDVQTVLVGFKALPMKTNQMEKDVYNQATVALDIAMLRLEKELCDVLHQHKRHVQPDYLAVSSRRKDIVYDESFVSLDDEVIVEASSHEDDEQISDFYNSDLVDPIVLPHIKAIANAMFACEYDQPFCEAFIGVQREALEEYMVTLEMERFSCVDVLRMDWEDLNGAMRKWTKVVKIITQVYLASEKQLCDQILGDFE-SISTACFIEISKDAILSLLNFGEAVVLRSCKPEMLERFLSMYEVSAEILVDVDNLFPDETGSSLRIAFHNLSKKLADHTTTTFLKFKDAIASDESTRPFHGGGIHHLTRYVMNYLKLLPEYTDSLNSLLQNIHVDDSIPEKTGEDVLPS-----TFSPMARHLRSIVTTLESSLERKAQLYADEALKSIFLMNNFRYMVQKVKGSELRRLFGDEWIRKHIASYQCNVTNYERSTWSSILALLRDNNDSVRTLRERCRLFSLAFDDVYKNQTRWSVPDSELRDDLHISTSVKVVQSYRGFLGRNAVRIG-EKHIRYTCEDIENMLLDLF 624          

Query:  164 LKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDT--PERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAEN-----------ASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDS------VVSYSPEDLTDYLSEILCGSVL 579
            L  +A+ M+  G+ +E    Y  +R++++ ++L  LGVE+ S   V++M+ +  E KI  WI+ +++SV  LF  E+ +C+ I D   P R+ +F+  T I   G ++ FG+   +A  + +PEK+F +LD+YE + +     E +F S   + +    +     LA++V+  ++DFE AI+ + ++  V  G +H LT YV  Y+  L DY   L  +F ++               +  +P +++   ++ ++  +   LDGKS  ++D AL+ LFL NN+ Y+V   R       LG+D +  H   V+++  +Y+ ++W+K+L  I    +                + F+ FN  FEE  + QC W V D  +R+ ++ ++   ++  Y  F  ++   ++S       + ++PEDL   L++   G  L
Sbjct:  164 LHDLAQQMVKAGHQQELFKTYRDIRRAVLAQSLEKLGVERHSKYDVERMNQDVFEAKIMNWIHYIRISVKLLFAAEKEICHQILDGVEPFRDQSFAEITTISF-GMLLSFGYA--IAISRRSPEKVFVILDMYEIMIELQPEFELIFGSKPCTEMKEDALNLTKLLAQTVKETIADFEVAIEMDATETVVMDGSVHALTSYVARYVKFLFDYEPTLRQLFQEF---------------NSNDPDTKLKSVMTGIMRALRNNLDGKSRQFEDAALTQLFLMNNVYYIVRNFRREEAKNFLGDDLVQTHRRIVQQHAKQYQTISWNKILQCITVQSSKSGLIKNESIKKTLVKEKFKTFNSQFEELHQRQCQWSVSDVELRESLRLAIAEVLLPAYGSFLKRFGPMIESGKNSQKYIRFTPEDLERMLNDFFQGKNL 580          

Query:  162 SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSF---SQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIF-DTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKE-NSKIPVPGGGIHP-LTRYVMNYISLLN--DYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCK-LDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMK--VKEYVSKYERMAW---SKVLSS----IPENPTAENAS------DIFQNFNLAFEEAC-RTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSE 572
            SN  A  +C+        C+++Y  VR     +AL  L  + L       + +M+WE LE  I  W    +V+   +   E+ LC  +  +  +  I   CF +I  +   + F F E VA+    P+K+F++LD++E++      +  +F  +S   ICA+    E  + ++   +  +F   I+   +  +P P  G  P + RY +NY+  L+  +Y   ++ +     +T L      + S  ++    ++ K     ++  L + ++ K    KD  L  +F+ N   Y+ ++ +N+ LG +LGE + IK   K   +E    Y++ AW    K+L      I E    +  S      +  + F     E C R +  + +PD  +R+++++S    +V  Y EF   Y   L   V  SP+ L   L +
Sbjct:  261 SNTLAANDCLDI------CIDIYVKVRYKRAAKALMKLNPDYLRTYTPEGIDEMEWENLETSITLWTQHFEVATKKVLLSEKKLCESVLGEIIDGLIHPECFVKISDKIMAVFFRFGEGVARSNKEPQKLFKLLDMFESLEKLKPYVLEIFDGESGEDICARFRELEKLIIDASSKVFWEFGLQIEGNVDGFLPPPQDGSVPKIVRYAVNYLKYLSTENYRTTMAKVL----RTELTWKTELMLSSKQSETDEDLLKHAICNVMEALQRNIESKRLSCKDKILVNIFMMNTYWYMYMRTKNTELGDLLGEKY-IKESYKAVAEESAYLYQKQAWLVLVKILDQDDDDIKEQKQGKEKSIGRLVNEKIETFFKCLSEICDRHRSFYSIPDVDLREQMRDSTVKLLVPVYAEFLESYSGFLQRKVYPSPQRLQGLLGK 685          

Query:    1 MPKHRSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNS--ISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVES---------------TVDHRRSISEIDDE---FSDEDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKN-TPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWP---QTPLPESYYKIPSHDEANP----PSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPT----AENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYR-----VGLDSVVS-YSPEDLTDYLSEILCGS 577
            M KH    F   PPP+ P         + + +++ V E +    ++I+KW S   S+S ++   TNS +EA++++ AV+ LQ  M  L++ + +S+KLI AQ+LM+ AMK LE+EF+R+L  N      + +SV S                 +   S  E  DE   FS  DS ++     +LK IA+CMI TGY+KECV VY  VRKSI+DE L NL +E+ +  QVQKMDWE LE KIK W+ AVK++V  LF GER+L +++F +    I  S FTEI +EGA++LF FPE  +K K  TPEKMFR LD+YEA+++ +  IES+F  +S + + +QVI S  RL ++ R M++DFESAIQKE SK P+ GGG+HPLTRYVMNY+S L DYSD+++ IF +W     TPLP+S Y I   DEANP     S +S R++W+IL  LCK+DGK++ YKD+ALSYLFLANN+QYVVVKVR+S L  +LG+DW+ +HE KVK Y  K+E++AW KVL  +PE PT     E A  +   FN  FE + R Q  WV+PDP +RD+IK +L  K++    EFY   R     VG +  +S Y+PED+ +YLS++  GS
Sbjct:    1 MGKH---LFRSSPPPEKPTA-------HLSLAESAVQECMSNINTVISKWTSPAASSSDDFLFSTNSRREAEEFVTAVRHLQSTMHRLVSVNPSSEKLIYAQNLMQSAMKLLESEFHRVLKANREYLDPECVSVRSYRSSRFSTSTTTSVSDSEDESSYEENADEEHRFSGGDSDAM----DDLKMIADCMISTGYAKECVRVYKTVRKSIVDETLHNLQMERFNLHQVQKMDWEILESKIKTWLKAVKLAVRKLFFGERILADHVFSSSGL-IVESSFTEITQEGALILFTFPEYASKIKKLTPEKMFRFLDMYEALANLYVEIESIFYFESAAAVRSQVINSLARLGDATRLMMTDFESAIQKETSKTPIIGGGVHPLTRYVMNYLSFLADYSDSIAAIFENWKLSVPTPLPDSLY-ISGGDEANPEDLYSSPVSVRIAWVILLTLCKIDGKAQPYKDVALSYLFLANNLQYVVVKVRSSTLKVLLGDDWVFRHEEKVKLYADKFEKLAWGKVLDLLPEIPTDEISPEEAKVLVARFNDEFETSYRKQTSWVIPDPKLRDQIKITLSQKLMLVCTEFYRMNRFAYGMVGDNEAISRYTPEDIGNYLSDLYFGS 599          

Query:    1 MPKHRSFFFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNS--ISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVES---------------TVDHRRSISEIDDE---FSDEDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKN-TPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWP---QTPLPESYYKIPSHDEANP----PSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPT----AENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYR-----VGLDSVVS-YSPEDLTDYLSEILCGS 577
            M KH    F   PPP+ P         + + +++ V E +    ++I+KW S   S+S ++   TNS +EA++++ AV+ LQ  M  L++ + +S+KLI AQ+LM+ AMK LE+EF+R+L  N      + +SV S                 +   S  E  DE   FS  DS ++     +LK IA+CMI TGY+KECV VY  VRKSI+DE L NL +E+ +  QVQKMDWE LE KIK W+ AVK++V  LF GER+L +++F +    I  S FTEI +EGA++LF FPE  +K K  TPEKMFR LD+YEA+++ +  IES+F  +S + + +QVI S  RL ++ R M++DFESAIQKE SK P+ GGG+HPLTRYVMNY+S L DYSD+++ IF +W     TPLP+S Y I   DEANP     S +S R++W+IL  LCK+DGK++ YKD+ALSYLFLANN+QYVVVKVR+S L  +LG+DW+ +HE KVK Y  K+E++AW KVL  +PE PT     E A  +   FN  FE + R Q  WV+PDP +RD+IK +L  K++    EFY   R     VG +  +S Y+PED+ +YLS++  GS
Sbjct:    1 MGKH---LFRSSPPPEKPTA-------HLSLAESAVQECMSNINTVISKWTSPAASSSDDFLFSTNSRREAEEFVTAVRHLQSTMHRLVSVNPSSEKLIYAQNLMQSAMKLLESEFHRVLKANREYLDPECVSVRSYRSSRFSTSTTTSVSDSEDESSYEENADEEHRFSGGDSDAM----DDLKMIADCMISTGYAKECVRVYKTVRKSIVDETLHNLQMERFNLHQVQKMDWEILESKIKTWLKAVKLAVRKLFFGERILADHVFSSSGL-IVESSFTEITQEGALILFTFPEYASKIKKLTPEKMFRFLDMYEALANLYVEIESIFYFESAAAVRSQVINSLARLGDATRLMMTDFESAIQKETSKTPIIGGGVHPLTRYVMNYLSFLADYSDSIAAIFENWKLSVPTPLPDSLY-ISGGDEANPEDLYSSPVSVRIAWVILLTLCKIDGKAQPYKDVALSYLFLANNLQYVVVKVRSSTLKVLLGDDWVFRHEEKVKLYADKFEKLAWGKVLDLLPEIPTDEISPEEAKVLVARFNDEFETSYRKQTSWVIPDPKLRDQIKITLSQKLMLVCTEFYRMNRFAYGMVGDNEAISRYTPEDIGNYLSDLYFGS 599          

Query:   29 QTFSDAIVDENIETAQSLITKWNSISTS--SNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTV-DHRRSISEIDDEFSDEDS-----SSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPE----NVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWP---QTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTA----ENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFY-MKYRV---------GLDSVVSYSPEDLTDYLSEIL 574
            Q+   A +   IE+A  +I +WN+ + +      +F  +  EA  ++  VK LQ  M  L++ D  S++L+ +  LM++AMK+L+ EFY+ILS N      +S+S  S++   R S S+  D   D D+        T + ++LK+IAECMI +GY+KEC+++Y  +RKSI+DE ++ L VEK S  +V+KM WE +E KI+ W+ AVKVS+ TLF GE++LC+++F++ +  I  SCF++I ++GA++LFGFPE      +K  + PEK+FR+LD+Y AI+ NWQ IES+F+ DS S + +  + S + L+ES+R++L +FES IQK++SK+ VPGGG+HPLT  VM+++SLL DYS+ L DI +  P   ++ LPESY+ +    + +P SE++ R +W+IL +LCK+D KS  YKD ++ YLFL NN+Q+VV + R+SNL  +LGEDW+ +H  K++++   Y+R+AW  V++++PEN T     E   + F+ F+ +FE A     + VV DP +RDEIK S+  K+V  YREFY  +  V          L+SVV ++PED+ +YLS++ 
Sbjct:   32 QSLESAAIYGVIESAADIIERWNTETNTFAKVTCMFYENKPEAMMFIERVKDLQKTMDVLVSEDPNSERLLRSHKLMQIAMKRLQKEFYQILSMNRAYLDPESVSTRSSLTSARSSYSDFPDYVEDLDTIIELEEVSTNVMTDLKSIAECMIGSGYAKECLSIYKSIRKSIIDEGIYRLEVEKTSTGKVKKMSWEVMELKIRSWLKAVKVSMETLFKGEKILCDHVFESSD-AIRESCFSDISRDGALLLFGFPEIINTKTSKKHSPPEKVFRLLDMYTAIAGNWQAIESIFSFDSISVVRSLALKSLISLSESIRSLLVEFESGIQKDSSKVVVPGGGVHPLTISVMDHLSLLADYSNVLVDILAGSPPPDRSLLPESYFNVSES-DDSPSSELTIRFAWIILVLLCKIDRKSIHYKDFSIQYLFLTNNLQHVVSRARSSNLKNLLGEDWITRHFAKMRQFAGSYKRLAWGPVVATLPENRTVEMTPEEVKERFEKFSESFENAYSKHSVCVVADPNIRDEIKVSISRKLVPIYREFYNTRGSVILGEGDGARNLNSVVRFTPEDIENYLSDLF 604          

Query:   23 PSSPQNQTFSDAIVDENIETAQSLITKW--NSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEI----DDEFSDE---DSSSLTTLE-------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWP---QTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTA----ENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKY------RVGLDSVVSYSPEDLTDYLSEILCGS 577
            P+SP NQTFS ++++E +E A+S+I KW  NS S +   SLF++S +EAK+++  ++ L+ AM +LI++ S S KL+ AQ LM++AM +LE EF++ILS N ++   +S+S  S++       ++    DDE  DE      ++T +E       S+LK IAE MI  GY KEC+  Y ++RKSI+DE L  LG+EK   S+  +MDW+ LE  IK WI A K+ V TL  GE++LC+++F +    I  SCF EI  E  I LF FPE VA+ K +PE++FR++DLY AISD    IE +F  DS + +   V++S  +L +S+ T L +FES IQK++SK    GGGIH LTR  M++IS L++YS  LS+I ++ P    T + ESY+  P  ++ +    +S  L+WLIL  LCKLD K+E YKD++LSYLFL NN+Q+VV  VR+++L  +LG+DWL KHE K++ Y + YE  AW+ V  S+PE  ++    E A   F+ F+  FEEA   Q   V+ D  +R+E+K S+  K+V +YREFY KY         ++ +VS+ P++L +YLS++  G+
Sbjct:   29 PASPLNQTFSQSMMEETVEAAESIIKKWDPNSPSYTKIISLFSHSRREAKEFIRCIRDLRRAMHFLISQHSKSAKLVLAQHLMQIAMARLEKEFFQILSSNRDQLDPESVSGHSSISSNSEFEDVMQSSDDEEEDELKKAGETITKVEKAAALVMSDLKVIAETMISCGYGKECIKSYKLIRKSIVDEGLHLLGIEKCKISRFNRMDWDVLEHMIKNWIKAAKIGVITLLRGEKLLCDHVF-SASSTIRESCFYEIVNEAGINLFKFPELVAEKKPSPERIFRLMDLYAAISDLRPDIELIFHFDSVAAVKTLVLSSLKKLKDSIYTSLMEFESTIQKDSSKALTAGGGIHKLTRSTMSFISSLSEYSRVLSEILAEHPLKKNTRMLESYFTAPILEDEHNNHAVSVHLAWLILIFLCKLDIKAESYKDVSLSYLFLVNNIQFVVDTVRSTHLRNLLGDDWLTKHEAKLRSYAANYEIAAWANVYISLPEKTSSRLSPEEAKTHFKRFHAVFEEAYMKQSSCVITDAKLRNELKVSIAKKIVPEYREFYGKYLPTLSKERNIEMLVSFKPDNLENYLSDLFHGT 611          

Query:    9 FFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKW--------NSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLS---VESTVDHRRSISEI----DDEFSDEDSSSL---------TTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSE----ISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAEN-ASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCG 576
              KP       ++ P   Q Q FS++++ +++E A + I +W        +S S S +      +  E +++L  +  LQYA+   +A +  S KL   Q LM+ AMK LE EFYR+L  N      +S+S    ES +  R S +      D E   E SS L         +    +LK IA CMI +GY K+CV +Y   RK I+ + L +LG EKL+ +Q+QK++WE LE KIK W+   +V++ TLF GER+L ++IF +   ++A SCF +I  + A+ LF F   VAK + T EK+F  LD+Y+ I      I+ +F+ DST+ +  Q   S  +L+ESV  M+++F+S+I KE+SK  + GGG+H LTRYVMN+I  L DYSD+L+ I  +    PLPE Y+   S  E NP S     ++ RL+WLIL +LCK+D KS LY D ALSYLFLANN+ YVV KVR SNL  +LG+DW+  HE+KV +Y+ KYE+MAW  V++S+P + TA   A +  + FN AFEEA +    WVVPDP +RDEI+ S+  K++  Y  FY K+ VG  ++V ++PEDL +Y++++  G
Sbjct:    3 LLKPTTLSKSSKVGPQ--QQQGFSESLIGDSVEAADAFICQWVTPHLCDSSSSSCSLSSLFSAQNRLEGRRFLEVLGKLQYAIQSTVAMNPDSAKLAKGQDLMRKAMKHLEKEFYRVLKSNRRFLSPESVSGWSSESNIPSRSSGTASDSSSDGELYSESSSELGKDIGGGGNSDAIVDLKMIANCMISSGYEKDCVKIYKKFRKKIIVDTLSHLGFEKLTSTQMQKLEWEILEKKIKIWVIVARVAITTLFNGERILSDHIFSS---SVAESCFVDITLQSALNLFIFSLTVAKSRKTAEKIFPTLDVYQTILQLTPKIDQIFSYDSTAAVRLQANESLEKLSESVNAMMTEFQSSITKESSKSAISGGGVHQLTRYVMNFIVFLADYSDSLATILKE-SSLPLPEDYFS--SSGEENPGSGDRSPMAARLAWLILVLLCKIDAKSRLYNDSALSYLFLANNLHYVVTKVRTSNLRLVLGDDWVANHEVKVNQYLEKYEKMAWGDVIASLPGDSTAGTEAEESLRRFNEAFEEAYKKHKTWVVPDPNLRDEIQASIARKLMPGYTGFYKKHPVGSCNIVRFTPEDLNNYITDLYVG 591          

Query:   24 SSPQNQTFSDAIVDENIETAQSLITKW--NSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSD--------EDSSSLTTLE-------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWP---QTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPT---AENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKY------RVGLDSVVSYSPEDLTDYLSEILCGS 577
            +SP NQ F+ A+++E +ETA S+I KW  N+ S +   SLF +S +EAK+++  V+ L+ AM +L+++DS S KL  AQ+LM++AM +LE EF++ILS N ++   +S+S +S++       ++     D        +   S+T +E       S+LKAIAE MI  GY KECV +Y  VRKSI+DE L  LG+E    S+  + DW  LE  IK WI A K+ + TLF GE++LC+++F +   +   SCF EI  E A  LF FPE VAK K + E++F ++DL  AISD WQ IE +F  D+ + + +Q + S  +L  S+ + L+DFES IQK+ +K   PGGGIH LTR  MN+IS L+ YS  LS+I +D P    T L ESY + P  ++      +S   +WLIL +LCKLD K+E YKD++LSYLFLANN+Q ++  V ++ L  +LG+DWL KHE K+  Y   YE  AWS V  S+PE PT    E A   F+ F+ AFEEA   Q   VVP+  +RDE+K S+  K+V +YREFY KY         ++ +V + P++L +Y+S++  G+
Sbjct:   30 ASPLNQNFTQAMMEETVETADSVIRKWDPNTPSFTKIVSLFNHSRKEAKEFIRCVRDLRRAMHFLVSQDSQSPKLALAQTLMQIAMARLEKEFFQILSSNRDKLDPESVSGQSSISSNSEFEDVMGSDDDDESDNEMRKAGESITQVEKASAMVMSDLKAIAESMISCGYGKECVKIYKRVRKSIVDEGLSLLGIEIYKGSRFHRTDWVTLEHMIKNWIKAAKIGIATLFRGEKLLCDHVF-SASNSTRESCFYEIANEAATNLFKFPEFVAKEKKSHERIFPLMDLQAAISDLWQDIEMIFHFDAVAGVKSQALTSLQKLKVSIHSALTDFESIIQKDTTKALTPGGGIHKLTRSTMNFISSLSKYSGVLSEILADHPLPRNTRLLESYVRAPISEDEQHNHALSVHFAWLILVLLCKLDTKAEHYKDVSLSYLFLANNLQIIIETVGSTPLRNLLGDDWLNKHEDKLCAYAGNYEIAAWSNVFMSLPEEPTDLSPEEAKIYFRRFHTAFEEAYMKQSSRVVPNAKLRDELKVSIAKKLVPEYREFYRKYLPMLGQERNIEILVRFKPDNLENYISDLFHGT 611          

Query:   29 QTFSDAIVDENIETAQSLITKW------NSISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVEST--VDHRRSISEIDDEFSDEDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHD----EANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSI----PENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEILCGS 577
            Q+FS++++ ++IE A++L  KW      +S S S +    T++  E ++++  +  LQYA+  ++  +  S KL  A +L+ +AMK+LE EFYRIL  N      +S+SV S+   + R  +S        E++  +T    +LK IA+CMI +GY  EC+ +Y  +R SIM +AL NLG E LSF ++QK+DW+ +E  IK W+ A KV +  LF GER+L +++F +P  ++A SCFTEI  + A+ LF FP +VA+CK T EK+F  LD+Y+ IS     IE +F+ DST+ +  Q   S   L E + +M+++FE++I KE+SK P+ GG +H LTRYVMN+I  L DY + L+ + ++    PLPE Y+     D    E    S ++ R++WLIL +LCK+D KS +Y D+ALSYLFLANN+ YV+ KVR SN+  +LG++W+  HE KV +Y+ KYE++AW +V++S+     E      A +    FN  FEEA + Q  WVVPD  +RD++K+S+  K+      FY KY V     V ++PEDL +YLS++  G+
Sbjct:   21 QSFSESLLMDSIEAAETLTRKWISPDLSSSSSCSLSSIFSTDNRVEGRRFVEVINSLQYAIQGVVLVNPESPKLTRAHNLVTIAMKQLEKEFYRILKSNRRNLDPESVSVRSSPSFNARNKVSIYSQVPKSEEADVMT----DLKMIADCMISSGYENECIKIYKKIRGSIMVKALSNLGFENLSFGKIQKLDWDSMEKNIKKWLEATKVLITNLFEGERILSDHVF-SPSVSVAESCFTEITLDSALTLFIFPVSVARCKKTVEKIFLTLDIYQTISQLMPQIEEIFSYDSTTAVRLQAADSLNNLGEEINSMVAEFEASITKESSKTPIRGGSVHQLTRYVMNFIVFLADYHECLAGVLTE-STLPLPEDYFGNNDEDNNEGETGSSSTVTTRIAWLILVLLCKIDTKSRMYNDMALSYLFLANNLHYVISKVRTSNMRVVLGDEWVTNHEGKVTQYLEKYEKIAWGEVITSLFDSNEEMLEEHVAKERLMRFNEGFEEAFQKQSEWVVPDSKLRDDLKDSVTEKLTTVTTTFYEKYHVENWEEVKFAPEDLDNYLSDLFLGT 579          

Query:   28 NQTFSDAIVDENIETAQSLITKWNS---ISTSSN---YSLF-TNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSDEDSSSLTTLESNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDSVVSYSPEDLTDYLSEI 573
            +Q+FS+++++  IE A+S+I +W S   + +SS     SLF T + +EAK++++AV  L   M+ LI+ + TS KL+ A++LM+++M  L  EFYRIL  N      +S+S+ S+              SD DS S +    +LK IA+CMI +GYSKEC  +Y  +RKSI++EAL  LG E L+FSQ+QK++WE +E KI+ W+     +VNTLF GE++L +++F +    I  S F EI  + A+ LF FPE +AKC+ +PEK+F  LD+Y+ I D    I  LF+SDSTS + +QV  + + L E V +M+ +FES+I KE+SK  + GGGIH LTRYVMN+I  L DYSD LSDI S  P  P PE         ++   S +  R+S LIL +LCK+D KS LY D+ALSYLFL NN+ YVVVKVR+SNL  +L EDW+ KHE KVK+YV+K+E + W ++++S+ ++ T   A +  + F+  FEEA + Q  W+VPD  +RDEIK S+ + ++ +Y  F  + RV L   V + PED+ +YLS++
Sbjct:   21 HQSFSESLMEHTIEDAESIIHRWISPEHVHSSSFCFISSLFSTENREEAKRFIDAVTTLHSGMIRLISVNPTSMKLVKAENLMRISMTHLSKEFYRILKSNRRYLDPESVSIRSSKA------------SDSDSDSDSNTMDDLKMIADCMISSGYSKECFKIYKRIRKSIINEALNQLGFENLTFSQIQKLEWEVMEKKIRKWLRTTTRAVNTLFSGEQILSDHVFSSSSSTIRESAFAEITSQTALALFTFPEKMAKCRKSPEKIFLTLDVYQTIVDLLPKINELFSSDSTSTVRSQVDLTLVNLREGVVSMIDEFESSISKESSKSLISGGGIHQLTRYVMNFIVFLADYSDTLSDIISK-PSLPSPE------EEKDSGDSSPVKSRISRLILFLLCKIDAKSRLYNDVALSYLFLINNVNYVVVKVRSSNLKTVLSEDWVKKHEAKVKKYVAKFEEIVWGEMMTSLSDDVTM-TAEEGIKRFSDGFEEAYKRQTGWIVPDSKLRDEIKRSVGMMIIPRYSGFCERNRVRLLENVGFDPEDIGNYLSDL 553          

Query:    8 FFFKPPPPKSPPQLPPSSPQNQTFSDAIVDENIETAQSLITKWNS--ISTSSNYSLFTNSPQEAKQYLNAVKMLQYAMMYLIARDSTSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVESTVDHRRSISEIDDEFSDEDSSSLTTLE---------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVA---KCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDW-----PQTPLPESYYKIPSHDEANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNSNLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENPTA-------ENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYR-----VGLDSV--VSYSPEDLTDYLSEILCGSVLS 580
            FF K    +  P L   S  +++     V++ I+ A  +I KWN+  +S    YSLF  S ++AK+++  VK LQ AM  LI  D  S+KL+ AQ+LM++AMK+L+ EF +ILS N      +S+S  S       +S  DD + +  S+  + +E         + LK+IA+CMI  G +KEC   Y  +RKSI+DE+++ LGVE +S S+ +KM  E +E K+  WI AVKVS+ TLF GE+ LC+ IF++      F CF +I KEGA++LFGFPE +    K    PEK+F +LD+Y  I+DN   IE++F+  S S +  Q  +S  RL+ES+   L DFES I+K++SK  V GGG+HP+T   MN+IS L +YS+AL +I          +  LP+SY+ +   +E+   SE+  R +W+IL +LCK+DGK+E+YKD ++ YLFLANN+Q+VV + R++N+  +LG DW+ K+  KV+++   YER+AW  + S  P   T+       E A   F+ FN  FE  C  Q   +V DP + DE++ S+  K++  YR+FY  +R      G +    V Y+PED+ ++LSE+  G  +S
Sbjct:    9 FFSKMTSSRKRPSLSLPSKSHESTD---VNKTIDNAAEIIEKWNTEYVSDKKFYSLFCESKRDAKKFVKRVKELQNAMDLLIREDPNSEKLLRAQNLMQIAMKRLQKEFLQILSMNRAHLDPESISSRSPTS---VVSNDDDVWHESRSAGDSIIEVEEVSKNSRTELKSIADCMIAAGCAKECATTYKSIRKSIVDESIYRLGVENISSSKAKKMPCEVVELKMNRWIEAVKVSMKTLFNGEKTLCDEIFESSVSLREF-CFRDISKEGALLLFGFPETITLRDKKNPHPEKIFPLLDMYCTITDNLLAIEAIFSFPSISNVRTQAHSSLSRLSESILAHLMDFESQIRKDSSKTVVRGGGVHPMTISAMNHISRLAEYSNALINILKGSSSSSSAKALLPKSYFNVSESEESPV-SELKARFAWMILVLLCKIDGKAEMYKDFSMQYLFLANNLQHVVSRARSTNVKHVLGNDWIAKNSEKVRQFARSYERLAWGPLASMCPAISTSEAVEMSPEEAMMQFKKFNETFESTCEAQSECIVLDPKLLDEMRISIGRKLLPVYRDFYNAHRNAVMLAGTEGQWNVRYNPEDIGNHLSELFSGKGIS 606          

Query:   26 PQNQTFSDAIVDENIETAQSLITKWNSISTSSNYS--LFTNSPQEAKQYLNAVKMLQYAMMYLIARDS-----------TSQKLITAQSLMKLAMKKLETEFYRILSQNTNRYGSKSLSVES---------TVDHRRSISEIDDEFSDEDSSSLTTLE-----------------------SNLKAIAECMIFTGYSKECVNVYSIVRKSIMDEALFNLGVEKLSFSQVQKMDWEFLEWKIKCWINAVKVSVNTLFPGERVLCNYIFDTPERNIAFSCFTEICKEGAIMLFGFPENVAKCKNTPEKMFRVLDLYEAISDNWQLIESLFASDSTSPICAQVIASELRLAESVRTMLSDFESAIQKENSKIPVPGGGIHPLTRYVMNYISLLNDYSDALSDIFSDWPQTPLPESYYKIPSHD--EANPPSEISKRLSWLILTILCKLDGKSELYKDIALSYLFLANNMQYVVVKVRNS-NLGFILGEDWLIKHEMKVKEYVSKYERMAWSKVLSSIPENP-----------TAENASDIFQNFNLAFEEACRTQCLWVVPDPIMRDEIKESLELKVVCKYREFYMKYRVGLDS------VVSYSPEDLTDYLSEILCGSVLSHSTTDHFKR 589
            P+N   SD     N+ETA+ +I +W+S +T       +F +   E  ++L AV  +Q ++  +    S             +  + A S +++AM +LE EF  IL  +T  +   SL +E           V    +++  ++E +    S  + L                        S+L++I + M+  GYS+EC+ VY  VRKS M+     LG+ K+S   VQ+++WE +E KI+ WI A KV +  +F  E+ LC  +FD     +  +CF E  K  A+ LF FPE ++  + +PEK+F++LDL++A++D    IE++F SDS+  I AQ +  + RLAE+ R +LS+FE+A+ +E S +PVPGG IHPLTRYVMNYI +++DY   L D+    P T    S    P  D  E +  S +   L WLI+ +   L+ KS+ Y+D +L+++F+ NN+ Y+V KV+ S  L  ++G+ +L K     +   + Y+R  W +VL+S+ +             +     + F+ FN  FEE  RTQ  W VPD  +R+E++ SL   ++  YR F  ++R  ++S       + YS ED+   + +   G    ++T  H +R
Sbjct:    4 PENSLDSDG---SNLETAERIILRWDSAATDGARGKMIFQSDRDEVDRFLRAVDEIQRSLSSVSFSSSSSSAATSAATVVDEHEVKANSAIQIAMARLEDEFRNILLSHTTTFEPDSLFLEEPSVSPSLTVEVGEDTTVTPEEEELNSPGGSGSSRLTRRRSSYRSTSSIREMDLISPEAVSDLRSIVQRMVAAGYSRECIQVYGTVRKSAMEAIFKQLGIVKISIGDVQRLEWEVVEGKIRKWIRAAKVCIRVVFSSEKRLCEQLFDGICTAMDETCFMETVKASALRLFTFPEAISISRRSPEKLFKILDLHDALTDMLPDIEAIFDSDSSDAIRAQAVEIQSRLAEAARGILSEFENAVLREPSIVPVPGGTIHPLTRYVMNYIVMISDYKQTLDDLIMSNPSTG---SDPNTPDMDFTELDSKSPLDLHLIWLIVVLHFNLEEKSKHYRDTSLAHIFIMNNIHYIVQKVKRSPELREMIGDHYLRKLTGIFRHAATNYQRATWVRVLNSLRDEGLHVSGSFSSGVSRSALRERFKAFNTMFEEVHRTQSTWSVPDAQLREELRISLSEHLIPAYRSFLGRFRGHIESGRHPENYLKYSVEDIETIVLDFFEG----YTTPPHLRR 622