Vfaba.Hedin2.R1.1g051760.1

Query:    1 MAYPSKFEHKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSIHGNCDV-NLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQA--QDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKD---DEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            MA P++ + K IEQTLI+PS T+TISLPLTFLDLPLAGPIYV+RQFFYHFP+S  +F KT LPSLKHSLSLTLQ+FFPLAGNLISPPPP+KP+I+ TQKDSV FT+IE+SANFNHLS+N+HPKN+KD+NHLVPKLT KTT DDND IENNTFIFPLL LQ SVFPNHGLCIAITYCHVMDD CC+HFMK+WS +H NC+V +LK TPCFDR I RDPKGLENVFL DYFEERKTWK K   Q   ++YVKATIVF KEEIERMK   LNQWKK DHE + PQ LSKFVVTCGF+W+SLVKTRYRN+ D   DEKEEYFRFAGDCRDR+GY IPEGYFGNCLTLCHAT KRK MKGE GFVN VK IE A+ EMK EPFKD  EWR+TFKKMYE GSVLLVTGSPKFNVYE DFGFG+PVKVEM+HSFKCMSIAESGDREGGLEVGLVFKSGEFE FC+ IE GLEA K
Sbjct:   47 MASPTQQDLKLIEQTLIIPSSTATISLPLTFLDLPLAGPIYVRRQFFYHFPHSTTHFCKTTLPSLKHSLSLTLQHFFPLAGNLISPPPPHKPFILYTQKDSVTFTVIETSANFNHLSANHHPKNLKDYNHLVPKLTHKTTYDDND-IENNTFIFPLLALQASVFPNHGLCIAITYCHVMDDSCCSHFMKSWSFMHRNCEVVDLKSTPCFDRKIFRDPKGLENVFLRDYFEERKTWKEKLIGQTSEEEYVKATIVFAKEEIERMKIWALNQWKKNDHEVQAPQLLSKFVVTCGFIWSSLVKTRYRNENDNDDDEKEEYFRFAGDCRDRLGYKIPEGYFGNCLTLCHATVKRKVMKGEDGFVNGVKEIERAISEMKNEPFKDVGEWRDTFKKMYEVGSVLLVTGSPKFNVYETDFGFGRPVKVEMVHSFKCMSIAESGDREGGLEVGLVFKSGEFEYFCAVIEHGLEALK 513          

Query:    1 MAYPSKFEHKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSIHGNCDV-NLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQA--QDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKD---DEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            MA P++ + K IEQTLI+PS T+TISLPLTFLDLPLAGPIYV+RQFFYHFP+S  +F KT LPSLKHSLSLTLQ+FFPLAGNLISPPPP+KP+I+ TQKDSV FT+IE+SANFNHLS+N+HPKN+KD+NHLVPKLT KTT DDND IENNTFIFPLL LQ SVFPNHGLCIAITYCHVMDD CC+HFMK+WS +H NC+V +LK TPCFDR I RDPKGLENVFL DYFEERKTWK K   Q   ++YVKATIVF KEEIERMK   LNQWKK DHE + PQ LSKFVVTCGF+W+SLVKTRYRN+ D   DEKEEYFRFAGDCRDR+GY IPEGYFGNCLTLCHAT KRK MKGE GFVN VK IE A+ EMK EPFKD  EWR+TFKKMYE GSVLLVTGSPKFNVYE DFGFG+PVKVEM+HSFKCMSIAESGDREGGLEVGLVFKSGEFE FC+ IE GLEA K
Sbjct:    1 MASPTQQDLKLIEQTLIIPSSTATISLPLTFLDLPLAGPIYVRRQFFYHFPHSTTHFCKTTLPSLKHSLSLTLQHFFPLAGNLISPPPPHKPFILYTQKDSVTFTVIETSANFNHLSANHHPKNLKDYNHLVPKLTHKTTYDDND-IENNTFIFPLLALQASVFPNHGLCIAITYCHVMDDSCCSHFMKSWSFMHRNCEVVDLKSTPCFDRKIFRDPKGLENVFLRDYFEERKTWKEKLIGQTSEEEYVKATIVFAKEEIERMKIWALNQWKKNDHEVQAPQLLSKFVVTCGFIWSSLVKTRYRNENDNDDDEKEEYFRFAGDCRDRLGYKIPEGYFGNCLTLCHATVKRKVMKGEDGFVNGVKEIERAISEMKNEPFKDVGEWRDTFKKMYEVGSVLLVTGSPKFNVYETDFGFGRPVKVEMVHSFKCMSIAESGDREGGLEVGLVFKSGEFEYFCAVIEHGLEALK 467          

Query:    8 EHKFIEQTLIVPSLTSTISLP--LTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSIHGNCDV-NLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQ------DYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYR---NDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACKF 463
            E K IEQ L+ PS   T +    LTFLDLP AGP+YV+R FFYHFP+S  +F KT LPSLKHSLSLTLQ+FFPLAGNL  PP P+KP+I+CTQ DSV FTI+ESSA+FNHLS+N+HPKN+KD+N+L PKL++KTT D ND IENNTFIFPLL+LQ SVFPNHGLCIAITYCHVMDD CC+HFMK+WS IH NC+V +LK TPCFDRN LRDPKGLENVFL DYFEERKTWK+K   Q Q      +YVKATIVF KEEIERMK   L+QWKK D E + PQFLSKFVVTCGF+WAS+VKTR R   ++ DDEKEEYF F GDCR+R+GY IPEGYFGNCLTLCHAT KRKDMKGE G+VNAVKVIE  + EMK EPFKD  EWR+ FKKMYE GSVLLVTGSPKFNVYE DFGFGKP KVEM+H F CMSIAES +REGGLEVGLVFKS +F+ F S IEQGL+A KF
Sbjct:   14 EQKLIEQALVSPSTPRTTTTSLPLTFLDLPFAGPVYVERLFFYHFPHSTTHFCKTTLPSLKHSLSLTLQHFFPLAGNLQCPPQPHKPFILCTQNDSVAFTIVESSADFNHLSTNHHPKNLKDYNYLSPKLSRKTTYDGND-IENNTFIFPLLSLQASVFPNHGLCIAITYCHVMDDSCCSHFMKSWSFIHRNCEVVDLKSTPCFDRNFLRDPKGLENVFLRDYFEERKTWKDKLIGQTQSQTSEEEYVKATIVFAKEEIERMKIWALDQWKKNDCEVQAPQFLSKFVVTCGFIWASMVKTRCRKENDNDDDEKEEYFGFPGDCRERLGYKIPEGYFGNCLTLCHATMKRKDMKGEDGYVNAVKVIERVISEMKNEPFKDMGEWRDRFKKMYELGSVLLVTGSPKFNVYETDFGFGKPAKVEMVHPFTCMSIAESENREGGLEVGLVFKSEDFKYFSSIIEQGLQALKF 480          

Query:    9 HKFIEQTLIVPSL--TSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSIHGNCDV-NLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWK-NKSTSQAQ-------DYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKD-DEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACKF 463
            HK IEQT++ PS   T+T  LPLTFLDLP AGP+YV+R FFYHFP+S  +F KT LPSLKHSLSLTLQ+FFPLAGNL  P PP+KP+I+CTQ DSV FT+IESSANFNHLS+N HPKN++DFNHLVPKLT+KTT DD     N+ FIFPLL+LQV+VFPNHGLCIAI YCHVMDD+CCNH MK+WS IH   DV + K  PCFDR +LRDP+GLE++FL  Y+E+RKTW+ N+   + Q       D VKA IVFGKEEIE MK+ VLN+WKK D E + PQFLSK+VVTC FVW SLVK  +R++ + DEK+EYF F GDCRDR+GYTIPEGYFGNCL   HAT KR+D+KGE GFVNAVKVIE A+ EMK EP KDA +W  + KK+ EFG++L V GSPKFNVYE DFGFGKPVKVEMMHS KCMSIAESGDREGGLEVGL FKS ++E F S I+QGL+A KF
Sbjct:    4 HKLIEQTVVFPSTPRTTTTFLPLTFLDLPFAGPVYVERLFFYHFPHSTTHFSKTTLPSLKHSLSLTLQHFFPLAGNLHCPLPPHKPFILCTQNDSVTFTVIESSANFNHLSTNQHPKNLQDFNHLVPKLTEKTTFDDG----NDIFIFPLLSLQVTVFPNHGLCIAIKYCHVMDDNCCNHLMKSWSFIHRKGDVVDFKSQPCFDRQVLRDPEGLEDLFLKGYYEKRKTWEDNRLIGKTQSIEKHDEDCVKAIIVFGKEEIEGMKKWVLNEWKKKDQEIQAPQFLSKYVVTCAFVWVSLVKAMHRSNHNIDEKDEYFCFTGDCRDRLGYTIPEGYFGNCLAFNHATMKRRDVKGEDGFVNAVKVIEKAITEMKNEPLKDATKWEGSAKKIGEFGNLLFVRGSPKFNVYETDFGFGKPVKVEMMHSLKCMSIAESGDREGGLEVGLAFKSEDYECFSSVIQQGLQALKF 466          

Query:    8 EHKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSI--HGNCDVNL--KPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQ-----AQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDE-KEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            EHK + +  +VP++ +  +LPLTFLDLPLAGPIYV+RQFFY FP+S  +F +T LPSLK SLS TLQ+FFPLAGNLI PPPP+KP+I CT  DSV  TIIES A+F +LSSN HPK++KD +HLVPKLT   T DD       TFIFPL+ LQ +VFPNHGLCIAITYCHVMDD+CC+HFMK+WSSI   G  D+ L  K TPCFDR +L+DPKGLE +FL DYFEER +WK   TS+      +DYVKATIVFG+E+IE ++R VLNQWKK   E   PQ++SKFVV C FVWASL KTR  ND+++  KE+YF F  DCRDR+GY IPE YFGNCLTLC+A  KR D+KGE GFVNA KVIE AV +MKIEP KD   WRE+F KMY   S L+VTGSPKF VYE DFGFG+P KVEM+H FKC+S+AESGD EGGLEVGLV +S EFE+  S IEQGL+A K
Sbjct:    6 EHKLVGKIQVVPAVRTITTLPLTFLDLPLAGPIYVRRQFFYQFPHSTLHFSETTLPSLKTSLSKTLQHFFPLAGNLICPPPPHKPFIRCTDDDSVTLTIIESQADFKNLSSN-HPKSLKDLDHLVPKLTCTYTHDD-------TFIFPLVALQATVFPNHGLCIAITYCHVMDDNCCSHFMKSWSSICRSGGVDLTLVEKSTPCFDREVLKDPKGLEAIFLRDYFEERSSWKVGKTSEISNENTEDYVKATIVFGREDIEGLRRWVLNQWKK-SEEFNTPQYMSKFVVACAFVWASLDKTRCINDEEENVKEKYFGFTADCRDRLGYPIPETYFGNCLTLCYAMLKRNDLKGENGFVNAAKVIERAVADMKIEPLKDVEHWRESFMKMYVLESTLMVTGSPKFTVYETDFGFGRPTKVEMVHLFKCISLAESGDEEGGLEVGLVCRSTEFEDLFSVIEQGLKASK 461          

Query:    8 EHKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSI--HGNCDVNL--KPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQ-----AQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDE-KEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            EHK + +  +VP++ +  +LPLTFLDLPLAGPIYV+RQFFY FP+S  +F +T LPSLK SLS TLQ+FFPLAGNLI PPPP+KP+I CT  DSV  TIIES A+F +LSSN HPK++KD +HLVPKLT   T DD       TFIFPL+ LQ +VFPNHGLCIAITYCHVMDD+CC+HFMK+WSSI   G  D+ L  K TPCFDR +L+DPKGLE +FL DYFEER +WK   TS+      +DYVKATIVFG+E+IE ++R VLNQWKK   E   PQ++SKFVV C FVWASL KTR  ND+++  KE+YF F  DCRDR+GY IPE YFGNCLTLC+A  KR D+KGE GFVNA KVIE AV +MKIEP KD   WRE+F KMY   S L+VTGSPKF VYE DFGFG+P KVEM+H FKC+S+AESGD EGGLEVGLV +S EFE+  S IEQGL+A K
Sbjct:    6 EHKLVGKIQVVPAVRTITTLPLTFLDLPLAGPIYVRRQFFYQFPHSTLHFSETTLPSLKTSLSKTLQHFFPLAGNLICPPPPHKPFIRCTDDDSVTLTIIESQADFKNLSSN-HPKSLKDLDHLVPKLTCTYTHDD-------TFIFPLVALQATVFPNHGLCIAITYCHVMDDNCCSHFMKSWSSICRSGGVDLTLVEKSTPCFDREVLKDPKGLEAIFLRDYFEERSSWKVGKTSEISNENTEDYVKATIVFGREDIEGLRRWVLNQWKK-SEEFNTPQYMSKFVVACAFVWASLDKTRCINDEEENVKEKYFGFTADCRDRLGYPIPETYFGNCLTLCYAMLKRNDLKGENGFVNAAKVIERAVADMKIEPLKDVEHWRESFMKMYVLESTLMVTGSPKFTVYETDFGFGRPTKVEMVHLFKCISLAESGDEEGGLEVGLVCRSTEFEDLFSVIEQGLKASK 461          

Query:    9 HKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSIHGNCDVNLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQA-------QDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            +KFIE++ + P+ ++T SLPLTFLDL LAGP+YV+RQFFYHF +    FY+T LPSLKH+LSLTLQ+FFPLAGNL+ PPPP+KP+I CT  D+V  TIIES A+FNHLSSN HPK++KD +HLVPKLT   T DD       TFIFPL+ LQ +VFPN GLCIAITYCHVMDD CC HFMK+WSSI G+  V+  P PCFDR +L+DPKGLE +FL DYFEER TWK+K   Q        +DYVKATI FG+E+IE MKR VLNQWK+ + E K PQ+LSKFV+TC FVW SLVK +YR+D DDE EEYFRFA DCRDR  Y IP  YFGNCLT CH   KRK++KGE GFV AVK I  A+ +MK EP K A  W+  F+KM+  GS +LVTGSPKF VYE DFGFG+P KVEM+HS KCMS+AESGD+EGGLE+GLVF+SGEFE F S IEQGL A K
Sbjct:    7 YKFIEKSQVAPATSTTTSLPLTFLDLSLAGPVYVRRQFFYHFSHPTHIFYETTLPSLKHTLSLTLQHFFPLAGNLLCPPPPHKPFIRCTHDDTVTLTIIESKADFNHLSSN-HPKSLKDLDHLVPKLTCTNTHDD-------TFIFPLVALQATVFPNQGLCIAITYCHVMDDSCCGHFMKSWSSICGSGGVDFTP-PCFDREVLKDPKGLEAIFLEDYFEERSTWKDKLFGQTPKHLGGDEDYVKATIAFGREDIEGMKRWVLNQWKR-NGELKAPQYLSKFVLTCAFVWTSLVKAKYRDD-DDEGEEYFRFAADCRDRFEYPIPATYFGNCLTKCHVVMKRKELKGEGGFVKAVKAIARAIGDMKTEPLKGAENWKALFRKMFILGSTVLVTGSPKFTVYETDFGFGRPTKVEMVHSLKCMSLAESGDKEGGLELGLVFRSGEFEYFISVIEQGLVALK 456          

Query:    8 EHKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSI--HGNCDVNL--KPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQ-----AQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKD-DEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            EHK +E+  + P++ +  +LPLTFLDLPLAGPIYV+RQFFYHFP+S  +F +T LP LK SLS TLQ+FFPLAGNL+ PPPP+KP+I CT  D V  TIIES A+F +LSSN  PK++KD +HLVPKLT   T        ++TFIFPL+ LQ +VFPNHGLCIAITYCHVMDD CC+HFMK+WSSI   G  D  L  K TPCFDR +L+DPKGLE +FL DYFEER TWK   TS+     ++DYVKATIVFG+E++E ++R VLNQWK+   E   PQ++SKFVVTC FVWASLVKTR RND++ D KEE+FRFA DCRDR+ + +P+ YFGNCLTLC+A  KR+D+KGE GFVNAVKVIE AV +MK E FKDA  WRE+F KM+  GS L+VTGSPKF VYE DFGFG+P KVEM HSFK MS+AE+GD EGGLE+GLV  S E+E   S IEQGL+  K
Sbjct:    6 EHKLVEKFQVGPAVRTITTLPLTFLDLPLAGPIYVRRQFFYHFPHSTLHFCETILPCLKTSLSQTLQHFFPLAGNLLCPPPPHKPFIRCTGDDFVTLTIIESEADFKNLSSNR-PKSLKDLDHLVPKLTCSNT-------HHDTFIFPLVALQATVFPNHGLCIAITYCHVMDDSCCSHFMKSWSSICRSGGVDFTLVEKSTPCFDREVLKDPKGLEAIFLRDYFEERSTWKVGKTSEVSNGNSEDYVKATIVFGREDVEGLRRWVLNQWKR-SKEFNTPQYISKFVVTCAFVWASLVKTRCRNDEEEDVKEEFFRFAADCRDRLEHPVPKTYFGNCLTLCYAMLKREDLKGESGFVNAVKVIERAVADMKSELFKDAENWRESFTKMFVLGSTLIVTGSPKFTVYETDFGFGRPTKVEMAHSFKGMSLAETGDNEGGLEIGLVCTSTEYEYLISLIEQGLQISK 461          

Query:    8 EHKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSI--HGNCDVNL--KPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQ-----AQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKD-DEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
            EHK +E+  + P++ +  +LPLTFLDLPLAGPIYV+RQFFYHFP+S  +F +T LP LK SLS TLQ+FFPLAGNL+ PPPP+KP+I CT  D V  TIIES A+F +LSSN  PK++KD +HLVPKLT   T        ++TFIFPL+ LQ +VFPNHGLCIAITYCHVMDD CC+HFMK+WSSI   G  D  L  K TPCFDR +L+DPKGLE +FL DYFEER TWK   TS+     ++DYVKATIVFG+E++E ++R VLNQWK+   E   PQ++SKFVVTC FVWASLVKTR RND++ D KEE+FRFA DCRDR+ + +P+ YFGNCLTLC+A  KR+D+KGE GFVNAVKVIE AV +MK E FKDA  WRE+F KM+  GS L+VTGSPKF VYE DFGFG+P KVEM HSFK MS+AE+GD EGGLE+GLV  S E+E   S IEQGL+  K
Sbjct:    6 EHKLVEKFQVGPAVRTITTLPLTFLDLPLAGPIYVRRQFFYHFPHSTLHFCETILPCLKTSLSQTLQHFFPLAGNLLCPPPPHKPFIHCTGDDFVTLTIIESEADFKNLSSNR-PKSLKDLDHLVPKLTCSNT-------HHDTFIFPLVALQATVFPNHGLCIAITYCHVMDDSCCSHFMKSWSSICRSGGVDFTLVEKSTPCFDREVLKDPKGLEAIFLRDYFEERSTWKVGKTSEVSNGNSEDYVKATIVFGREDVEGLRRWVLNQWKR-SKEFNTPQYISKFVVTCAFVWASLVKTRCRNDEEEDVKEEFFRFAADCRDRLEHPVPKTYFGNCLTLCYAMLKREDLKGESGFVNAVKVIERAVADMKSELFKDAENWRESFTKMFVLGSTLIVTGSPKFTVYETDFGFGRPTKVEMAHSFKGMSLAETGDNEGGLEIGLVCTSTEYEYLISLIEQGLQISK 461          

Query:    9 HKFIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCNHFMKTWSSI--HGNCDVNL--KPTPCFDRNILRDPKG-LENVFLGDYFEERKTWKNKSTSQA-------QDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDE--KEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEACK 462
             K +E++ + P+ ++T SLPLTFLDL LAGP+YV+RQFFYHFP+  + FY+T LPSLKH+LSLTLQ+FFPLAGNL+ PPPP+KP+I CT  D+V  TIIES A+FNHLSSN HPKN+KD  HLVPKLT  T        E +TFIFP++ LQV+VFPN+GLCIAITYCHVMDD CC HFMK+WSSI   G  D+ L  K  PCFDR IL+DPKG LE +FL DYF+ER TWK+K   Q        +D++KATI FG+++IE +KR VLN WKK + E K PQ+LSKFVVTC FVW SLVK +YR+D + E  KEEYFRFA DCRDR+ Y IPE YFGNCLT C+A  KRK++KGE GFVNAVK I  A+ +MK EP + A  WR  F+KM+  GS +LVTGSPKF+VYE DFGFG+P KVEM+HS KCMS+AESGD+EGGLE+GLVF+SGEFE F S IEQG  A K
Sbjct:    7 QKLVEKSEVSPATSTTTSLPLTFLDLSLAGPVYVRRQFFYHFPHHTEIFYETTLPSLKHTLSLTLQHFFPLAGNLLCPPPPHKPFIRCTDDDTVTLTIIESKADFNHLSSN-HPKNLKDLGHLVPKLTCTTMH------EEDTFIFPIVALQVTVFPNNGLCIAITYCHVMDDRCCGHFMKSWSSICRSGGVDLTLVEKSPPCFDRKILKDPKGSLEAIFLRDYFQERSTWKDKLIGQTPKHVCDDEDFLKATIAFGRDDIESLKRYVLNHWKK-NAELKAPQYLSKFVVTCAFVWVSLVKAKYRDDDEGEEMKEEYFRFAADCRDRLDYPIPETYFGNCLTRCYAVLKRKELKGEGGFVNAVKAIARAITDMKTEPLRGAENWRALFRKMFVLGSTVLVTGSPKFSVYETDFGFGRPTKVEMVHSPKCMSVAESGDKEGGLELGLVFRSGEFEYFISVIEQGFVALK 466          

Query:    9 HKFIEQTLIVP--SLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYI-ICTQKDSVVFTIIESS-ANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCC-NHFMKTWSSIHGN-----CDVNLKPTPCFD-RNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFA--GDCRDRIGYT--IPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREM-KIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREG--GLEVGLVFKSGEFENFCSTIEQGLE 459
            +  IE   I P     ++ +LPLTF D P          FF+ +  S + F +  +P+LKHSLS+TLQ+FFP AG LI PP P+ PY+     +DS+VFT+ ES+  +F+ L S++ PK+I   + ++PKL       +   +       P++ +QV++FP  G+CI  +  HV+ D    +HFMK W S+  +       V L   P    RNI++DP  +    L + F  + + K+ S    ++ V+AT    +++I+ +K  V  Q      E + P  +S FVVT  F+W SL+KT  ++ + + K+E F      DCR+R+ YT  IP+ YFGNC+     + K+ D+ GE   + A   I + +++M   +  K A  W +  +K         + G+PK  +Y++DFG GKP K+E++H     SIA S  R+G  G+E+G+  +  + + F S +++G++
Sbjct:    8 YNIIETCHISPPKGTVASTTLPLTFFDAPWLSLPLADSLFFFSYQNSTESFLQDFVPNLKHSLSITLQHFFPYAGKLIIPPRPDPPYLHYNAGEDSLVFTVAESTETDFDQLKSDS-PKDISVLHGVLPKLPPPHVSPEGIQMR------PIMAMQVTIFPGAGICIGNSATHVVADGVTFSHFMKYWMSLTKSSGKDPATVLLPSLPIHSCRNIIKDPGEVAAGHL-ERFWSQNSAKHSSHVTPENMVRATFTLSRKQIDNLKSWVTEQ-----SENQSP--VSTFVVTLAFIWVSLIKTLVQDSETEAKDEVFHLMINVDCRNRLKYTQPIPQTYFGNCMAPGIVSVKKHDLLGEKCVMAASDAITARIKDMLSSDLLKTAPRWGQGVRKWVMSHYPTSIAGAPKLGLYDMDFGLGKPCKMEIVHIETGGSIAFSESRDGSNGVEIGIALEKKKMDVFDSLLQKGIK 461          

Query:   19 PSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPN----KPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCCN-HFMKTWSSIHGNCDV--------NLKPTPCFDRNILRDPKGLENVF----LGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKT--RYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREM---KIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREGG--LEVGLVFKSGEFENFCSTIEQGLEAC 461
            PS     SLPLTF D+       V   +FYHFPYS  +F +T +P+LKHSLS+TLQ++FP  G LI  P P+    KP I   + DSV  T  E++ +FN LS+ NHP+  ++F  LVP L        N   E++    P+ ++QV+ FPN G+ I +T  H + D      F+K W+S+   C+         N  P P FDR ++ +P+  EN      LG +++            + D V+AT V  +  I  +K++VL Q   +       ++ S F VTCG++W+ +VK+       K +++ E F  +  CR R+   +PE YFGNC   C  T K   +KGE GFV A K+I   + +M   K    + A  W + FK        + ++G+PK N Y+IDFG+GK +K E++      S++ S  +E     E+G+ F S + E F      GLE+ 
Sbjct:   19 PSTIGHRSLPLTFFDIAWLLFPPVHHLYFYHFPYSKSHFTETVIPNLKHSLSITLQHYFPFVGKLIVYPNPHDSTRKPEIRHVEGDSVALTFAETTLDFNDLSA-NHPRKCENFYPLVPPL-------GNAVKESDYVTLPVFSVQVTYFPNSGISIGLTNHHSLSDANTRFGFLKAWASV---CETGEDQPFLKNGSP-PVFDR-VVVNPQLYENRLNQTRLGTFYQAPSL-----VGSSSDRVRATFVLARTHISGLKKQVLTQLPML-------EYTSSFTVTCGYIWSCIVKSLVNMGEKKGEDELEQFIVSVGCRSRLDPPLPENYFGNCSAPCIVTIKNGVLKGENGFVMAAKLIGEGISKMVNKKGGILEYADRWYDGFKIP---ARKMGISGTPKLNFYDIDFGWGKAMKYEVVSIDYSASVSLSACKESAQDFEIGVCFPSMQMEAFGKIFNDGLESA 457          

Query:   10 KFIEQTLIVP--SLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQ-KDSVVFTIIESS-ANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCC-NHFMKTWSSIHGN-----CDVNLKPTPCFD-RNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDK----DDEKEEYFRFA--GDCRDRIGYT--IPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREM-KIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREG--GLEVGLVFKSGEFENFCSTIEQGLE 459
            K IE   I P      + +LPLTF D P          FF+ +  S + F +  +P+LKHSLS+TLQ+FFP AG LI PP P+ PY+     +DS+VFT+ ES+  +F+ L S++ PK+I   + ++PKL       +   +       P++ +QV++FP  G+CI  +  HV+ D    +HFMK W S+  +       V L   P    RN+++DP  +    L + F  + + K+ S    ++ V+AT    +++I+ +K  V  Q      E + P  +S FVVT  F+W SL+KT  ++ +    +++K+E F      DCR+R+ YT  IP+ YFGNC+     + K+ D+ GE   + A   I + +++M   +  K A  W +  +K         + G+PK  +Y++DFG GKP K+E++H     SIA S  R+G  G+E+G+  +  + + F S ++QG++
Sbjct:    9 KIIETCHISPPKGTVPSTTLPLTFFDAPWLSLPLADSLFFFSYQNSTESFLQDFVPNLKHSLSITLQHFFPYAGKLIIPPRPDPPYLHYNDGQDSLVFTVAESTETDFDQLKSDS-PKDISVLHGVLPKLPPPHVSPEGIQMR------PIMAMQVTIFPGAGICIGNSATHVVADGVTFSHFMKYWMSLTKSSGKDPATVLLPSLPIHSCRNMIKDPGEVGAGHL-ERFWSQNSAKHSSHVTPENMVRATFTLSRKQIDNLKSWVTEQ-----SENQSP--VSTFVVTLAFIWVSLIKTLVQDSETKANEEDKDEVFHLMINVDCRNRLKYTQPIPQTYFGNCMAPGIVSVKKHDLLGEKCVLAASDAITARIKDMLSSDLLKTAPRWGQGVRKWVMSHYPTSIAGAPKLGLYDMDFGLGKPCKMEIVHIETGGSIAFSESRDGSNGVEIGIALEKKKMDVFDSILQQGIK 465          

Query:   12 IEQTLIVPSLTST--ISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPP-PNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCC-NHFMKTWSSIH--GNCDVNLKP--TPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDK--DDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVRE-MKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMH----SFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGL 458
            IEQ  +VPS  S   ++LPLT+ D        ++R  FY  P S   F +T +P+LK SLSLTL+Y+ PLAGN+  P      P +     +SV     ES  +FN+L    HP+N KDF H VP+L +     D   ++    + P+L +QV++FPNHG+ I  T  HV  D      F++ W+ ++  G  +  L     P +DR++++DP G+      +  + +   K        D V+ T +  + +I ++K  VL +  K+ H T        F VTC +VW  ++K+     +  D+   E+F  A DCR +    +P  YFGN L    A  ++ D+ G+ GF  AV++I  A+R+ MK E +  +  W + + K+ +    L V GSPK ++Y  DFG+G+P K+E +         MS+++S D +G LE+GL         F +    G+
Sbjct:    5 IEQCQVVPSPGSATELTLPLTYFDHVWLAFHRMRRILFYKLPISRPDFVQTIIPTLKDSLSLTLKYYLPLAGNVACPQDWSGYPELRYVTGNSVSVIFSESDMDFNYL-IGYHPRNTKDFYHFVPQLAEPK---DAPGVQ----LAPVLAIQVTLFPNHGISIGFTNHHVAGDGATIVKFVRAWALLNKFGGDEQFLANEFIPFYDRSVIKDPNGVGMSIWNEMKKYKHMMKMSDVVTPPDKVRGTFIITRHDIGKLKNLVLTRRPKLTHVT-------SFTVTCAYVWTCIIKSEAATGEEIDENGMEFFGCAADCRAQFNPPLPPSYFGNALVGYVARTRQVDLAGKEGFTIAVELIGEAIRKRMKDEEWILSGSWFKEYDKV-DAKRSLSVAGSPKLDLYAADFGWGRPEKLEFVSIDNDDGISMSLSKSKDSDGDLEIGLSLSKTRMNAFAAMFTHGI 450          

Query:   10 KFIEQTLIVPSLTST---ISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPN---KPYIICTQKDSVVFTIIESSANFNHLSSNN--HPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHG-NCDVNLKPT---PCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQ-DYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTR----YRNDKDDEKE-EYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREM---KIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQG 457
            K +E+  + P   +T   +SLP+TF D+P      ++   FY FPY   +F  T +P+LK SLSLTL+++ PL+GNL+ P       K      + DS+   + ES  +F++L  +      ++    +++P++ +  T+ D         + PL+ +QV+VFPN G+ +A+T  H + D      F+  W+ I+    D +L      P FDR+I++D  GLE  F  +  +  + +    +   + + V+AT V    EI+++K +VLN        ++P   ++ F +TCG+VW  +VK++         +DE E EYF F  DCR  +    P  YFGNCL  C A A  K++ G+ G + AV  I  A+ +    +     DA  W      +      L +TGSPKF+ Y +DFG+GKP K ++  +   + + + +S D E G+E+G+       + F    E+G
Sbjct:    8 KVLEKCQVTPPSDTTDVELSLPVTFFDIPWLHLNKMQSLLFYDFPYPRTHFLDTVIPNLKASLSLTLKHYVPLSGNLLMPIKSGEMPKFQYSRDEGDSITLIVAESDQDFDYLKGHQLVDSNDLHGLFYVMPRVIR--TMQDYK-------VIPLVAVQVTVFPNRGIAVALTAHHSIADAKSFVMFINAWAYINKFGKDADLLSANLLPSFDRSIIKDLYGLEETFWNEMQDVLEMFSRFGSKPPRFNKVRATYVLSLAEIQKLKNKVLNL-----RGSEPTIRVTTFTMTCGYVWTCMVKSKDDVVSEESSNDENELEYFSFTADCRGLLTPPCPPNYFGNCLASCVAKATHKELVGDKGLLVAVAAIGEAIEKRLHNEKGVLADAKTWLSESNGIPS-KRFLGITGSPKFDSYGVDFGWGKPAKFDITSVDYAELIYVIQSRDFEKGVEIGVSLPKIHMDAFAKIFEEG 464          

Query:   12 IEQTLIVPSLTSTIS------LPLTFLDLPLAGPIYVKRQFFYHFPYSP-DYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHGNCDVNLKP-----TPCFDRNILRDPKGLENVFL-------GDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCL--TLCHATAKRKDMKGEYGFVNAVKVIESAVREM---KIEPFKDAAEWRETFKKM-YEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEA 460
            IE   + P+  S I+      LPLTF DLP      VKR FFY    S  D+F+   LP LK SLSL L+ + PL G++   P   KP II ++   V+ TI ES A+F+HLS     + + + + LVPKL      DD+             ++Q+++FPN G  I +   H V+D    + F+K W+ I   C   L+      TP +DR++++ P  L+   +        D    R      S+    D V AT+V  + +IER++ +V N          P   LS FV+   + W   VK R  N    ++     F GD RDR+   +P  YFGNC+    C+   K  +   E GFV A ++I   V+ +   KIE   D      +F+    +FG+   + GS +  VYE DFG+G+PVKV++  +   + +++AE  D  GG+E+G+  K  E ++  S    GL +
Sbjct:    6 IETARVTPTDYSVINSANLHKLPLTFFDLPWLLFQPVKRVFFYELTESTRDHFHSIILPKLKDSLSLILRNYLPLTGHITWEPNEPKPSIIVSENGVVLVTIAESDADFSHLSGYGQ-RPLSELHALVPKLPVS---DDSA---------TAFSIQITLFPNQGFSIGVAAHHAVLDGKTSSTFIKAWAQI---CKQELQSMPENLTPSYDRSLIKYPTYLDEKMIELVRSLKEDQTNIRSLTSLPSSKLGDDVVLATLVLSRADIERLREQVKN--------VSPSLHLSTFVIAYAYAWTCFVKARGGN---KDRSVSLLFVGDFRDRLDPKLPGTYFGNCMIPVGCY-NRKAAEFMEEKGFVTAAEIISDLVKGLSSRKIETIADTFVEGFSFQSWSTQFGT---IAGSTRLGVYEADFGWGRPVKVDIVSIDQGEAIAMAERRDESGGVEIGMCLKKTEMDSVVSFFNNGLHS 451          

Query:   19 PSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNK-PYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDH-CCNHFMKTWSSIHGNC-----DVNLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEP--FKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMH---SFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGL 458
            P   +  S+PLTF D+       + +  FY FP S  +F ++ +P LK SLS TL +FFPL+ NLI P  P K P       DSV FTI ESS +F+ L  N     ++ +N  VPKL            E++  +F +  +QV++FP  G+ I I   H + D      F+  WSS+  +      D   K  P FDR++++ P   ++++  +    +   +++  S   D ++ T VF + +I+++K  + ++   + H       LS FV    ++WA + K+   ++  D ++ +F    D R R+   +PE YFGNCL+      +R+++ GE G   A +VI + +++   +    +   +W    +K  +  S   V GS K ++Y  DFG+GK  K E++        M++ ++ D EGGLEV L     + + F +    G+
Sbjct:   11 PDSVAEQSVPLTFFDMTWLHFHPMLQLLFYEFPCSKQHFSESIVPKLKQSLSKTLIHFFPLSCNLIYPSSPEKMPEFRYLSGDSVSFTIAESSDDFDDLVGNRPESPVRLYN-FVPKLPPIVE-------ESDRKLFQVFAVQVTLFPGRGVGIGIATHHTVSDAPSFLAFITAWSSMSKHIENEDEDEEFKSLPVFDRSVIKYPTKFDSIYWRNAL--KFPLQSRHPSLPTDRIRTTFVFTQSKIKKLKGWIQSRVPSLVH-------LSSFVAIAAYMWAGITKSFTADEDQDNEDAFFLIPVDLRPRLDPPVPENYFGNCLSYALPRMRRRELVGEKGVFLAAEVIAAEIKKRINDKRILETVEKWSPEIRKALQ-KSYFSVAGSSKLDLYGADFGWGKARKQEILSIDGEKYAMTLCKARDFEGGLEVCLSLPKDKMDAFAAYFSLGI 444          

Query:   12 IEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSP-DYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSI--HGNCDVNLKPTPCFDRNILRDPKGLEN-VF-LGDYFEERKTWKNKST-----SQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNC-LTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAE-WRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDRE--GGLEVGLVFKSGEFENFCS 452
            I +  +V +    + LPLTF DL       ++R  FY    S  D F+ + LP L+ SLSL L +F PL+G+L   P   KP+I+   KD+V  T++ES A+F+++SS    +   +   LVP+L            + ++    LL+LQ+++FPN G  I  T  H VMD    + F K+W+ I  HG    +       DR ++  P GLE  +F L  Y  E K +    T         D V+ T+   + +IE++K R  N+       T+    LS FVV+  +V   +VK+      D  +   F +A D R+R+   +P  YFGNC L +     K     G+ G+VN V+++  +VR +     +   E + +  K M      + VTGS +F +Y  DFG+G+PVK ++M  +K    + S  R+  GGLE+G+  K  E   F S
Sbjct:    8 ISRVSLVTNSVEPLVLPLTFFDLLWLKLNPIERVTFYKLTESSRDSFFSSILPKLEQSLSLVLSHFLPLSGHLKWNPQDPKPHIVIFPKDTVSLTVVESEADFSYISSKEL-RLETELRPLVPEL------------QVSSDSASLLSLQITLFPNQGFSIGTTVHHVVMDGKTASKFHKSWAHICKHGTTPQDFDLPTVLDRTVINVPAGLEQKIFQLSSYISEEKDYARTLTLPPAKEIDNDVVRVTLELTEVDIEKLKERAKNE------STRSDLHLSTFVVSYAYVLTCMVKS---CGGDANRPVRFMYAADFRNRLDPPVPLTYFGNCVLPIDFNGYKATTFLGKDGYVNGVEILSDSVRGLGSRNIESIWEVYEDGTKNMKLDTQNVTVTGSNQFGIYGSDFGWGRPVKTDVMSLYKNNEFSMSARRDEIGGLEIGISLKKCEMNVFLS 441          

Query:   19 PSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNK-PYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDD-HCCNHFMKTWSSIHG---------NCDVNLKPTPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKE-EYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVR---EMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMH---SFKCMSIAESGDREGGLEVGL 440
            P   + +S+PL+F D+       V+R  FYH P S   F  T +P LK SLSL L ++ P+AGNL+ P    K P +     DSV  TI ES+++F  L + NH ++   F  L+P +            E++  +  +  +Q+++FP  G+CI  +  H + D      F+  W  I+G         N   +L   P FDR+ + DP  ++ +F           K  S     + V++T +  + +IE++K             TK P            VW+ +VK+    DK DE   E F    D R R+   IPE YFGNC+    A  +R  +  E GF  A + I   +    + + E  + A  W     K +   SVL V+GSPKF++ + DFG+GK  K+E++        MS+  S D  GGLEVGL
Sbjct:   16 PPAANDLSIPLSFFDIKWLHYHPVRRLLFYHHPSSKSQFLHTIVPHLKQSLSLALTHYLPVAGNLLYPSNTEKFPQLRYAAGDSVPVTIAESNSDFESL-TGNHTRDADQFYDLLPPIPPIEE-------ESDWKLINIFAVQITLFPGEGICIGFSNHHCLGDARSIVGFISAWGEINGIGGYEGFLSNHSDSLS-LPIFDRSFINDPNKIDAIFW--KVLRNIPLKTASFPLPTNRVRSTFLLRRSDIEKLKT-----------ATKSPASSFVAAAAF--VWSCMVKS---GDKSDENAPELFIIPADARGRVDPPIPENYFGNCIVSSVAQVERGKLAAEDGFAVAAEAIGGEIEGKLKNRDEILRGAENWMSDIFKCFGM-SVLGVSGSPKFDLLKADFGWGKARKLEVLSIDGENHSMSLCSSSDFNGGLEVGL 427          

Query:   10 KFIEQTLIVPSLTST--ISLPLTFLDLPLAGPIYVKRQFFYHFPYSP---DYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSI--HGNCDVNLKPTPCFDRNILRDPKGLENVFL-------GDYFEERKTWK---NKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNC-LTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVT-GSPKFNVYEIDFGFGKPVKVEMMHSFKC--MSIAESGDREGGLEVGLVFKSGEFENFCS 452
            K I+ + + P+  S   + +PL+F DL        ++ FFY    S    D FY + LP L+ SLSL L +F    G+L       KP+++    D++  T+ E+ A+F+ +S     + ++    L P + +     D+  +         ++LQV++FP  G CI  T  H V+D      F K W+    HG     + PT   DR+++  P GLE   L        D  E  +T K    K  +   + ++ TI    E IE++K R   +       T+    LS FVVT   VW  +VK R     D  +   F +A D R+R+   +P  YFG C L +     K K+  GE GFVN V+++  +V+ +  +  +   +  E   K  ++G+ LLV  GS +  +YE DFG+G+P+  E M  +K    S+++  D  GG+E+G+  K  E + F S
Sbjct:    4 KVIKISRVSPATASVDPLIVPLSFFDLQWLKLNPTEQVFFYKLTESSSSRDVFYSSILPKLERSLSLILTHFRLFTGHLKWDSQDPKPHLVVLSGDTLSLTVAETDADFSRISG----RGLRPELELRPLIPELPIYSDSGAV---------VSLQVTLFPKQGFCIGTTAHHVVLDGKTAEKFNKAWAHTCKHGTIP-KILPT-VLDRSVVNVPAGLEQKMLELLPYLTEDDKENGRTLKLPPVKEINAKDNVLRITIEISPENIEKLKERAKKE------STRAELHLSTFVVTFAHVWTCMVKAR---SGDPNRPVRFMYAADFRNRLEPPVPVTYFGTCVLAMDFYKYKAKEFMGEDGFVNTVEILSDSVKRLASQGVESTWKVYEEGTKTMKWGTQLLVVNGSNQIGMYETDFGWGRPIHTETMSIYKNDEFSMSKRRDGIGGVEIGISLKKLEMDTFLS 444          

Query:   10 KFIEQTLIVP--SLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQ-KDSVVFTIIESS-ANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCC-NHFMKTWSSIHGN-----CDVNLKPTPCFD-RNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDK----DDEKEEYFRFA--GDCRDRIGYT--IPEGYFGNCLTLCHATAKRKDMKGEYGFVNAVKVIESAVREM-KIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDREG--GLEVGLVFKSGEFENFCSTIEQGLE 459
            K IE   I P      + +LPLTF D P          FF+ +  S + F +  +P+LKHSLS+TLQ+FFP AG LI PP P+ PY+     +DS+VFT+ ES+  +F+ L S++ PK+I   + ++PKL       +   +       P++ +QV++FP  G+CI  +  HV+ D    +HFMK W S+  +       V L   P    RN+++DP  +    L + F  + + K+ S    ++ V+AT    +++I+ +K  V  Q      E + P  +S FVVT  F+W SL+KT  ++ +    +++K+E F      DCR+R+ YT  IP+ YFGNC+     + K+ D+ GE   + A   I + +++M   +  K A  W +  +K         + G+PK  +Y++DFG GKP K+E++H     SIA S  R+G  G+E+G+  +  + + F S ++QG++
Sbjct:    9 KIIETCHISPPKGTVPSTTLPLTFFDAPWLSLPLADSLFFFSYQNSTESFLQDFVPNLKHSLSITLQHFFPYAGKLIIPPRPDPPYLHYNDGQDSLVFTVAESTETDFDQLKSDS-PKDISVLHGVLPKLPPPHVSPEGIQMR------PIMAMQVTIFPGAGICIGNSATHVVADGVTFSHFMKYWMSLTKSSGKDPATVLLPSLPIHSCRNMIKDPGEVGAGHL-ERFWSQNSAKHSSHVTPENMVRATFTLSRKQIDNLKSWVTEQ-----SENQSP--VSTFVVTLAFIWVSLIKTLVQDSETKANEEDKDEVFHLMINVDCRNRLKYTQPIPQTYFGNCMAPGIVSVKKHDLLGEKCVLAASDAITARIKDMLSSDLLKTAPRWGQGVRKWVMSHYPTSIAGAPKLGLYDMDFGLGKPCKMEIVHIETGGSIAFSESRDGSNGVEIGIALEKKKMDVFDSILQQGIK 465          

Query:   12 IEQTLIVPSLTSTIS------LPLTFLDLPLAGPIYVKRQFFYHFPYSP-DYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHGNCDVNLKP-----TPCFDRNILRDPKGLENVFL-------GDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCL--TLCHATAKRKDMKGEYGFVNAVKVIESAVREM---KIEPFKDAAEWRETFKKM-YEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLEA 460
            IE   + P+  S I+      LPLTF DLP      VKR FFY    S  D+F+   LP LK SLSL L+ + PL G++   P   KP II ++   V+ TI ES A+F+HLS     + + + + LVPKL      DD+             ++Q+++FPN G  I +   H V+D    + F+K W+ I   C   L+      TP +DR++++ P  L+   +        D    R      S+    D V AT+V  + +IER++ +V N          P   LS FV+   + W   VK R  N    ++     F GD RDR+   +P  YFGNC+    C+   K  +   E GFV A ++I   V+ +   KIE   D      +F+    +FG+   + GS +  VYE DFG+G+PVKV++  +   + +++AE  D  GG+E+G+  K  E ++  S    GL +
Sbjct:    6 IETARVTPTDYSVINSANLHKLPLTFFDLPWLLFQPVKRVFFYELTESTRDHFHSIILPKLKDSLSLILRNYLPLTGHITWEPNEPKPSIIVSENGVVLVTIAESDADFSHLSGYGQ-RPLSELHALVPKLPVS---DDSA---------TAFSIQITLFPNQGFSIGVAAHHAVLDGKTSSTFIKAWAQI---CKQELQSMPENLTPSYDRSLIKYPTYLDEKMIELVRSLKEDQTNIRSLTSLPSSKLGDDVVLATLVLSRADIERLREQVKN--------VSPSLHLSTFVIAYAYAWTCFVKARGGN---KDRSVSLLFVGDFRDRLDPKLPGTYFGNCMIPVGCY-NRKAAEFMEEKGFVTAAEIISDLVKGLSSRKIETIADTFVEGFSFQSWSTQFGT---IAGSTRLGVYEADFGWGRPVKVDIVSIDQGEAIAMAERRDESGGVEIGMCLKKTEMDSVVSFFNNGLHS 451          

Query:   27 LPLTFLDLPLAGPIYVKRQFFYHF--PYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNN-HPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSI--HGNCDVNLKPTPCFDRNILRDPKGLEN--VFLGDYFEE-----RKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDM-KGEYGFVNAVKVIESAVREMKIEPFKDAAEW----RETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLE 459
            LPLTF DL        +R  FY      S + F    LP L+ SLS+ L+++ PLAG L       KP II +  D V  T+ ES A+F+ +S     P++  +   LVP+L+      D+  +         L+LQV++FPN G CI I   H VMD      F+K+W+ I  HG  D+    TP  DR ++  P  L+   + L  YF E     R          + D V+ ++   +E IE+++ +   +  +  HE      LS FVV   ++W  LVKTR     D+ +   F +A D R+R+   +PE YFGNC+        + ++  GE GFVN V+++  +VR + +   +   E      ++ K   + GS   + GS +F +Y  DFG+GKP   E+  +   +  S++E  D  GG+E+GL  K  E + F    + GLE
Sbjct:   27 LPLTFFDLRWLQFHPTERVIFYKLIKDSSLESFLSVILPKLELSLSIVLRHYLPLAGRLTWSSQDPKPSIIVSPNDYVSLTVAESDADFSRISGKGIRPES--EIRSLVPELSLSC---DSPSV---------LSLQVTLFPNQGFCIGIASHHSVMDGKTVVRFIKSWAHICKHGAMDLPEDLTPVLDRTVINVPASLDAKIIELLSYFSEVKDSFRSLKLLPPKEISPDLVRISLELTRENIEKLREQAKRESARSHHELH----LSTFVVANAYLWTCLVKTR---GGDENRPVRFMYAADFRNRLDPPVPEMYFGNCVFPIGCFGYKANVFLGEDGFVNMVEILSDSVRSIGLRKLETICELYINGTKSVKPGTQIGS---IAGSNQFGLYGSDFGWGKPCNSEIASIDRNEAFSMSERRDEPGGVEIGLCLKKCEMDIFIYLFQNGLE 455          

Query:   12 IEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSP-DYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSI--HGNCDVNLKPTPCFDRNILRDPKGLEN-VF-LGDYFEERKTWKNKST-----SQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNC-LTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAE-WRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFKCMSIAESGDRE--GGLEVGLVFKSGEFENFCS 452
            I +  +V +    + LPLTF DL       ++R  FY    S  D F+ + LP L+ SLSL L +F PL+G+L   P   KP+I+   KD+V  T++ES A+F+++SS    +   +   LVP+L            + ++    LL+LQ+++FPN G  I  T  H VMD    + F K+W+ I  HG    +       DR ++  P GLE  +F L  Y  E K +    T         D V+ T+   + +IE++K R  N+       T+    LS FVV+  +V   +VK+      D  +   F +A D R+R+   +P  YFGNC L +     K     G+ G+VN V+++  +VR +     +   E + +  K M      + VTGS +F +Y  DFG+G+PVK ++M  +K    + S  R+  GGLE+G+  K  E   F S
Sbjct:    8 ISRVSLVTNSVEPLVLPLTFFDLLWLKLNPIERVTFYKLTESSRDSFFSSILPKLEQSLSLVLSHFLPLSGHLKWNPQDPKPHIVIFPKDTVSLTVVESEADFSYISSKEL-RLETELRPLVPEL------------QVSSDSASLLSLQITLFPNQGFSIGTTVHHVVMDGKTASKFHKSWAHICKHGTTPQDFDLPTVLDRTVINVPAGLEQKIFQLSSYISEEKDYARTLTLPPAKEIDNDVVRVTLELTEVDIEKLKERAKNE------STRSDLHLSTFVVSYAYVLTCMVKS---CGGDANRPVRFMYAADFRNRLDPPVPLTYFGNCVLPIDFNGYKATTFLGKDGYVNGVEILSDSVRGLGSRNIESIWEVYEDGTKNMKLDTQNVTVTGSNQFGIYGSDFGWGRPVKTDVMSLYKNNEFSMSARRDEIGGLEIGISLKKCEMNVFLS 441          

Query:   23 STISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYI-ICTQKDSVVFTIIESS-ANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCHVMDDHCC-NHFMKTWSSIHGN-----CDVNLKPTPCFD-RNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFA--GDCRDRIGYT--IPEGYFGNCL 335
            ++ +LPLTF D P          FF+ +  S + F +  +P+LKHSLS+TLQ+FFP AG LI PP P+ PY+     +DS+VFT+ ES+  +F+ L S++ PK+I   + ++PKL       +   +       P++ +QV++FP  G+CI  +  HV+ D    +HFMK W S+  +       V L   P    RNI++DP  +    L + F  + + K+ S    ++ V+AT    +++I+ +K  V  Q      E + P  +S FVVT  F+W SL+KT  ++ + + K+E F      DCR+R+ YT  IP+ YFGNC+
Sbjct:   24 ASTTLPLTFFDAPWLSLPLADSLFFFSYQNSTESFLQDFVPNLKHSLSITLQHFFPYAGKLIIPPRPDPPYLHYNAGEDSLVFTVAESTETDFDQLKSDS-PKDISVLHGVLPKLPPPHVSPEGIQMR------PIMAMQVTIFPGAGICIGNSATHVVADGVTFSHFMKYWMSLTKSSGKDPATVLLPSLPIHSCRNIIKDPGEVAAGHL-ERFWSQNSAKHSSHVTPENMVRATFTLSRKQIDNLKSWVTEQ-----SENQSP--VSTFVVTLAFIWVSLIKTLVQDSETEAKDEVFHLMINVDCRNRLKYTQPIPQTYFGNCM 334          

Query:   10 KFIEQTLIVPSLTST--ISLPLTFLDLPLAGPIYVKRQFFYHFPYSP---DYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSI--HGNCDVNLKPTPCFDRNILRDPKGLENVFL-------GDYFEERKTWK---NKSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNC-LTLCHATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVT-GSPKFNVYEIDFGFGKPVKVEMMHSFKC--MSIAESGDREGGLEVGLVFKSGEFENFCS 452
            K I+ + + P+  S   + +PL+F DL        ++ FFY    S    D FY + LP L+ SLSL L +F    G+L       KP+++    D++  T+ E+ A+F+ +S     + ++    L P + +     D+  +         ++LQV++FP  G CI  T  H V+D      F K W+    HG     + PT   DR+++  P GLE   L        D  E  +T K    K  +   + ++ TI    E IE++K R   +       T+    LS FVVT   VW  +VK R     D  +   F +A D R+R+   +P  YFG C L +     K K+  GE GFVN V+++  +V+ +  +  +   +  E   K  ++G+ LLV  GS +  +YE DFG+G+P+  E M  +K    S+++  D  GG+E+G+  K  E + F S
Sbjct:    4 KVIKISRVSPATASVDPLIVPLSFFDLQWLKLNPTEQVFFYKLTESSSSRDVFYSSILPKLERSLSLILTHFRLFTGHLKWDSQDPKPHLVVLSGDTLSLTVAETDADFSRISG----RGLRPELELRPLIPELPIYSDSGAV---------VSLQVTLFPKQGFCIGTTAHHVVLDGKTAEKFNKAWAHTCKHGTIP-KILPT-VLDRSVVNVPAGLEQKMLELLPYLTEDDKENGRTLKLPPVKEINAKDNVLRITIEISPENIEKLKERAKKE------STRAELHLSTFVVTFAHVWTCMVKAR---SGDPNRPVRFMYAADFRNRLEPPVPVTYFGTCVLAMDFYKYKAKEFMGEDGFVNTVEILSDSVKRLASQGVESTWKVYEEGTKTMKWGTQLLVVNGSNQIGMYETDFGWGRPIHTETMSIYKNDEFSMSKRRDGIGGVEIGISLKKLEMDTFLS 444          

Query:   11 FIEQTLIVPSLTST---ISLPLTFLDLPLAGPIYVKRQFFYHFP-YSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHGNCDVNLKP--TPCFDRNILRDPKGLENVFLGDYFEERKTWK-------------NKSTSQAQDYVKATIVFGKEEI----ERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDM-KGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFK-KMYEFGS---------VLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENF 450
             IE   + PS + +   +SLPLT+ DL       V+R  FY     +  +F    +P+LK SLS  L ++ PLAG LI  P  +KP I+ +Q D V F++ E++A+F+ L S N P    +   LVP L      DD+  I         ++ QV++FPN G CI ++  H V+D      F+K+W+ I  + D +L     P +DR +++ P   EN  L ++    K                N S     D V+ T+   +E+I    ER+KR V +         +    LS FV+   +V   +++ R     +  +   + F+ DCR  +    P  YFGNC+  C        M  GE G + A  ++  ++            EW E+F  K+ +F +         ++LV+GS +F VYE+DFG+G+P KV +  +     +S+AES D+ G +E+G   K  E +  
Sbjct:    7 IIEVARVTPSNSDSAESLSLPLTYFDLIYYKLRAVERVIFYRITNVTRPFFDSVIVPNLKTSLSSCLSHYLPLAGKLIWEPLDHKPTIVYSQNDDVSFSVAETNADFSSL-SGNEPFPSTELYPLVPALQSS---DDSASI---------VSFQVTLFPNQGFCIGVSAHHAVLDGKTTTMFLKSWAHICKHQDFSLPQDLIPTYDRTVIKSPTDSENKVLNEWRSFTKILAGGKEPANPKSLKLNPSFEIGPDVVRYTLQLTREDIQTLRERLKREVSSSSSSTSSSKE--LRLSTFVIVYSYVLVCIIRAR---GGEPHRPVGYAFSVDCRSLMNPPTP-NYFGNCIAGCSRMMLTAKMFMGEEGLLAAATMVSDSIE-----------EWDESFAWKIPDFVAYATLPPETQLILVSGSNRFGVYELDFGWGRPDKVMVVSISPGNGISMAESRDQNGSVEIGFSLKKHEMDTL 453          

Query:   11 FIEQTLIVPSLTSTISLPLTFLDLPLAGPIYVKRQFFYHFPYSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICT--QKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHGNCDVNLKP-----TPCFDRNILRDPKGLENVFLGDYFEERKTWKN----KSTSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQF-LSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLCHATAKRKDMKGE--------YGFVNAVKVIESAVREMKIEPF-KDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEMMHSFK--CMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLE 459
             +E   + P  +++++LPLT+ DL       V R  FYH P   +    + +  LK SLS TL ++ PLAG L+      KP I+ +   KD+V  T+ ES+ + +HLS  + P+   +F+ LVP+L      D++  +         L +QV+ FPN G  + +T  H V+D      F+K W+    NC    +       P  DR I++DP GLE   L  +        +     S     D ++ T    +E+I++++ RV       + E+   Q  LS FV+T  +V   +VK R     D  +     FA D R R+   +P  +FGNC+      +   D+K E         GF+ AV+ +   V  +  E   K+     E FK+M     ++ V GS +  +Y  DFG+GKPVKVE++   K   +S++ESGD  GG+EVG+  K  + E F S    GLE
Sbjct:   10 ILEVVQVSPPSSNSLTLPLTYFDLGWLKLHPVDRVLFYHVP---ELTRSSLISKLKSSLSATLLHYLPLAGRLVWDSIKTKPSIVYSPDDKDAVYLTVAESNGDLSHLS-GDEPRPATEFHSLVPELPVS---DESARV---------LAVQVTFFPNQGFSLGVTAHHAVLDGKTTAMFLKAWAH---NCKQEQEALPHDLVPSLDRIIVQDPTGLETKLLNRWISASNNKPSLKLFPSKIIGSDILRVTYRLTREDIKKLRERV-------ETESHAKQLRLSTFVITYAYVITCMVKMR---GGDPTRFVCVGFASDFRSRLNPPLPPTFFGNCI----VGSGDFDVKAEPILEEGEGKGFITAVETLTGWVNGLCPENIEKNMLLPFEAFKRMEPGRQMISVAGSTRLGIYGSDFGWGKPVKVEIVTIDKDASVSLSESGDGSGGVEVGVCLKKDDVERFGSLFSIGLE 449          

Query:   11 FIEQTLIVPS---LTSTISLPLTFLDLPLAGPIYVKRQFFYHFP-YSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHGNCDVNLKP--TPCFDRNILRDPKGLENVFLGDYFEERKTWKNKSTSQAQ---DYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQFLSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGY-TIPEGYFGNCLTLCHATAKRKDM-KGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLE 459
            FI  + + PS    +++++LPLTF DL       V+R  FY     +   F    +P+LK SLS +L ++ PLAG++I  P   KP I+ TQ D+V FT+ ES+++F+ L +   P +  + + LVP+L      DD+  +         ++ QV++FPN G CI +T  H V D      F+K+W+ +  + D +L     P +DR +++ P  ++   L  +    K    K   + +   D V+ T    +E IE+++ ++     K +  +     LS FV+T  +V+  L+ +      D  +   +RFA DCR  I    IP  YFGNC+           M  GE GFV A ++I  +V E+         E  ET++K       + V GS +F +Y +DFG+GKP K  +  +     +SIAES D  GG+E+G   K  E       + +G++
Sbjct:    7 FIHVSRVTPSNSNSSASLTLPLTFFDLLWLKHKAVERVIFYKLTDVNRSLFDSVIVPNLKSSLSSSLSHYLPLAGHIIWEPHDPKPKIVYTQNDAVSFTVAESNSDFS-LLTGKEPFSSTELHPLVPELQNS---DDSAAV---------VSFQVTLFPNQGFCIGVTTHHAVSDGKTTTTFLKSWAHLCKHQDSSLPDDLIPFYDRTVIKGPPEIDTKVLKIWHSIHKPKSLKLLPRPEIESDVVRYTFELTRENIEKLRDKL-----KRESSSFSSVRLSTFVITFSYVFTCLIGS---GGDDPNRPVGYRFAVDCRRLIDDPPIPLTYFGNCVYSAVKIPLDAGMFLGEQGFVVAARLISDSVEELDSNVAWKIPELLETYEKAPVDSQFVSVAGSTRFGIYGLDFGWGKPFKSLLVSIDQRGKISIAESRDGSGGVEIGFSLKKQEMNVLIDLLHKGIK 448          

Query:   10 KFIEQTLIVPS---LTSTISLPLTFLDLPLAGPIYVKRQFFYHFP-YSPDYFYKTKLPSLKHSLSLTLQYFFPLAGNLISPPPPNKPYIICTQKDSVVFTIIESSANFNHLSSNNHPKNIKDFNHLVPKLTQKTTLDDNDHIENNTFIFPLLTLQVSVFPNHGLCIAITYCH-VMDDHCCNHFMKTWSSIHGNCDVNLKP--TPCFDRNILRDPKGLENVFLGDYFEERKTWKNK-------------STSQAQDYVKATIVFGKEEIERMKRRVLNQWKKIDHETKPPQF-LSKFVVTCGFVWASLVKTRYRNDKDDEKEEYFRFAGDCRDRIGYTIPEGYFGNCLTLC-HATAKRKDMKGEYGFVNAVKVIESAVREMKIEPFKDAAEWRETFKKMYEFGSVLLVTGSPKFNVYEIDFGFGKPVKVEM--MHSFKCMSIAESGDREGGLEVGLVFKSGEFENFCSTIEQGLE 459
            K I+   + PS    + +++LPLTF DL       V+R  FY     S  +F    +P+LK SLS +L ++ PLAG L+  P   KP I+ T  D+V FT+ ES+A+F+ L +   P    +   LVP+L          H+ +++     ++ QV++FPN G CI++   H V+D     +F+K+W+    N D  L     P +DR +++DP  L+   L  +    K +                S     D  + T+   +E+I++++ R+  +       + P +  LS FV+   +    L+K R     D  +   + FA DCR  +   +P  YFGNC++ C   +   +    E GF+ A +++  +V  +         E  E F  +     VL V GS +F VY +DFG+G+P KV +  +   + +S AES D  GG+E+G   K  E +     + +GLE
Sbjct:   11 KVIDVARVTPSNSDSSESLTLPLTFFDLLWYKLHAVERVIFYKLTDASRPFFDSVIVPNLKTSLSSSLSHYLPLAGKLVWEPLDPKPKIVYTPNDAVSFTVAESNADFSRL-TGKEPFPTTELYPLVPEL----------HVSDDS--ASAVSFQVTLFPNQGFCISVNAHHAVLDGKTTTNFLKSWARTCKNQDSFLPQDLIPVYDRTVIKDPMDLDTKILNAWHRVAKVFTGGKEPENPKSLKLLWSPEIGPDVFRYTLNLTREDIQKLRERLKKESSSSSVSSSPKELRLSTFVIVYSYALTCLIKAR---GGDPSRPVGYGFAVDCRSLMVPPVPSSYFGNCVSACFKMSLTAETFMSEEGFLAAARMVSDSVEALDENVALKIPEILEGFTTLSPGTQVLSVAGSTRFGVYGLDFGWGRPEKVVVVSIDQGEAISFAESRDGSGGVELGFSLKKHEMDVLVDLLHKGLE 468